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The map label for this gene is clpX [H]

Identifier: 186475777

GI number: 186475777

Start: 1134547

End: 1135818

Strand: Direct

Name: clpX [H]

Synonym: Bphy_1012

Alternate gene names: 186475777

Gene position: 1134547-1135818 (Clockwise)

Preceding gene: 186475776

Following gene: 186475778

Centisome position: 32.61

GC content: 56.21

Gene sequence:

>1272_bases
ATGGCGGACAAGAAAGGTTCGAACAGCGAGAAGCTGTTGTATTGCTCGTTCTGCGGCAAAAGTCAGCACGAGGTTAAGAA
ACTGATTGCTGGCCCGTCGGTATTCATCTGCGATGAATGTATCGACCTGTGCAACGAAATCATTCGCGACGAAGCAGCGG
GCGCGGGTCTGGAAACGGGCCTGTCCAAGTCCGATCTGCCGAGTCCTCAAGAAATTCGCGACATTCTCGATCAATACGTG
ATCGGGCAAGAGCGCGCGAAGAAAATTCTCGCGGTCGCGGTGTACAACCACTACAAGCGTCTGAAACATCTCGACAAGAA
GGACGATGTCGAGTTGTCGAAGAGCAACATCCTGCTGATCGGCCCGACGGGCTCCGGCAAGACGCTGCTCGCGCAGACCC
TTGCGCGCCTTCTGAACGTGCCGTTCGTGATCGCCGACGCGACCACGCTGACGGAAGCCGGCTATGTCGGCGAAGACGTC
GAGAACATCATTCAGAAGCTGCTGCAAAACTGCAATTACGAAGTCGACAAGGCGCAGCGCGGTATCGTCTATATCGACGA
AATCGACAAGATCAGCCGCAAGTCGGACAACCCGTCGATCACCCGCGACGTGTCGGGCGAGGGCGTCCAGCAGGCTCTGC
TGAAGCTTGTCGAAGGAACGATGGCGTCGGTGCCGCCGCAAGGCGGTCGTAAGCATCCGAACCAGGATTTCATCCAGGTC
GATACGACCAATATCCTGTTCATCTGTGGCGGTGCGTTCGATGGCCTCGAAAAGGTGATCGTCGATCGTACGGAAAAGAC
GGGCATCGGCTTCGGCGCGAGCGTCAAGAGCAAGCAGGATCGTGACGCAGGCGAAGTGCTGCGCGAAGTCGAACCAGAAG
ATCTCATCAAATTCGGCCTGATTCCAGAACTGATCGGACGTTTGCCCGTCGTGGCGACGCTCGGCAAGCTGGACGAAACC
GCGTTGATGAAGATTCTGGTCGAACCAAAGAATGCACTCGTCAAGCAGTATCACAAGCTGTTCAACATGGAACGCGTCGA
GCTGGAGATTCGTCCCGCCGCGCTGCAAGCCATTGCCCGCAAGGCTATCCGTCGCAAGACGGGGGCACGCGGCTTGCGGT
CCATCCTGGAACAGGCATTGCTTGACGTAATGTATGAATTGCCGGCAATGAAGGGCGTGAGCAAAGTCATTATTGACGAC
AATGTCATTGATGGCGACGGAAAGCCTTTACTGATCTACGAGGACGCGCCAAAGGTGGCGGGTTCGAATTGA

Upstream 100 bases:

>100_bases
AAACGCCGTCACAGCTTTTGCGCATCCGTCCCGCCCCGGACTGAACGAGGCGGGCAAACGGCGTATCATGTCATTCGAGT
GTCCGGAGGCTCACACATCT

Downstream 100 bases:

>100_bases
TCGGCTGCCCGATTTTTGAAAAAAAGCCGTTCATGGCGACGTGAACGGCTTTTTTCGTTTATCGTGTCGACAGGATGGAC
CGTTTTTCTGGAGTCACTGA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAGAGLETGLSKSDLPSPQEIRDILDQYV
IGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
DTTNILFICGGAFDGLEKVIVDRTEKTGIGFGASVKSKQDRDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDET
ALMKILVEPKNALVKQYHKLFNMERVELEIRPAALQAIARKAIRRKTGARGLRSILEQALLDVMYELPAMKGVSKVIIDD
NVIDGDGKPLLIYEDAPKVAGSN

Sequences:

>Translated_423_residues
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAGAGLETGLSKSDLPSPQEIRDILDQYV
IGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
DTTNILFICGGAFDGLEKVIVDRTEKTGIGFGASVKSKQDRDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDET
ALMKILVEPKNALVKQYHKLFNMERVELEIRPAALQAIARKAIRRKTGARGLRSILEQALLDVMYELPAMKGVSKVIIDD
NVIDGDGKPLLIYEDAPKVAGSN
>Mature_422_residues
ADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAGAGLETGLSKSDLPSPQEIRDILDQYVI
GQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVE
NIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQVD
TTNILFICGGAFDGLEKVIVDRTEKTGIGFGASVKSKQDRDAGEVLREVEPEDLIKFGLIPELIGRLPVVATLGKLDETA
LMKILVEPKNALVKQYHKLFNMERVELEIRPAALQAIARKAIRRKTGARGLRSILEQALLDVMYELPAMKGVSKVIIDDN
VIDGDGKPLLIYEDAPKVAGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=329, Percent_Identity=52.5835866261398, Blast_Score=317, Evalue=2e-86,
Organism=Escherichia coli, GI1786642, Length=415, Percent_Identity=74.2168674698795, Blast_Score=620, Evalue=1e-179,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=46, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988663, Length=404, Percent_Identity=42.0792079207921, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71982908, Length=297, Percent_Identity=47.8114478114478, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71982905, Length=297, Percent_Identity=47.8114478114478, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=43.7751004016064, Blast_Score=187, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319704, Length=428, Percent_Identity=39.4859813084112, Blast_Score=275, Evalue=7e-75,
Organism=Drosophila melanogaster, GI24648289, Length=324, Percent_Identity=46.2962962962963, Blast_Score=285, Evalue=4e-77,
Organism=Drosophila melanogaster, GI24648291, Length=324, Percent_Identity=46.2962962962963, Blast_Score=285, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46372; Mature: 46241

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAGAGLETG
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHCC
LSKSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLI
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQR
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DTTNILFICGGAFDGLEKVIVDRTEKTGIGFGASVKSKQDRDAGEVLREVEPEDLIKFGL
ECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCC
IPELIGRLPVVATLGKLDETALMKILVEPKNALVKQYHKLFNMERVELEIRPAALQAIAR
HHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEECHHHHHHHHH
KAIRRKTGARGLRSILEQALLDVMYELPAMKGVSKVIIDDNVIDGDGKPLLIYEDAPKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCCEEEEECCCCCCC
GSN
CCC
>Mature Secondary Structure 
ADKKGSNSEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAGAGLETG
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHCC
LSKSDLPSPQEIRDILDQYVIGQERAKKILAVAVYNHYKRLKHLDKKDDVELSKSNILLI
CCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEEE
GPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQR
ECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHCC
GIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLVEGTMASVPPQGGRKHPNQDFIQV
CEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEE
DTTNILFICGGAFDGLEKVIVDRTEKTGIGFGASVKSKQDRDAGEVLREVEPEDLIKFGL
ECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHCC
IPELIGRLPVVATLGKLDETALMKILVEPKNALVKQYHKLFNMERVELEIRPAALQAIAR
HHHHHCCCHHHHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHCCHHEEEEECHHHHHHHHH
KAIRRKTGARGLRSILEQALLDVMYELPAMKGVSKVIIDDNVIDGDGKPLLIYEDAPKVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEECCCCCEEEEECCCCCCC
GSN
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA