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The map label for this gene is phbC [H]

Identifier: 186475734

GI number: 186475734

Start: 1082120

End: 1084108

Strand: Direct

Name: phbC [H]

Synonym: Bphy_0969

Alternate gene names: 186475734

Gene position: 1082120-1084108 (Clockwise)

Preceding gene: 186475733

Following gene: 186475735

Centisome position: 31.1

GC content: 61.64

Gene sequence:

>1989_bases
ATGGCTGCATCTCACACTTCCTCGACTTCTTCTCGCACGGACACCTCGTCGGACCGCACGCAGCAGCAAGCGAATGCGGC
AGGGGTGCACCAATGGTTCGACGCCTGGATGAACGCATGGCGTTCGCTGGGCGCCCAGGCTGCAGCAAACGGCAATCCTT
TTAGCGTTCCGTCCATGCCCGACTTCGCGAAAGCGGCGACGGCGCAGGCGGGTTCGCTACCGTTTTCCAATCCCTTGTTC
GAGCAAATAGCCAAACAGTTTGCGCAAACGCCTGGCCAACCGAATGGTGAGGCCGCGGGCCAGCCGTTCAACGCCTTGTT
CGGACCGGCATTCAATCCGCAGTTCGCACAACAGTTCACGCAGCAGATCGCCGGGTTGAAGATGCCAAGCGCATCGATTC
CGCCGAATCGTCTTCAGCAGTTGCAGTCCGACTATTCGCGTGAAGCAATGCAGTTGCTGCAACAGGCAGCACAGGCCACG
GCATCGGGCATCGAGCTCAAGGACCGGCGCTTCAGTTCCGAAGCCTGGAAGACGACGCCCATCTACACCCACACGGCTGC
GTGGTACCTGCTGAATGCGCGTTATCTGCAGGAACTGGTCGATGCGATCGAAACAGACCAGAAGACGCGCGAGCGCATCC
GTTTCGCCGTGCAGCAGTGGACGGCGGCCGCGTCGCCAAGCAACTTCTTTGCGCTGAATCCCGAGGCGCAGAAGACGCTG
CTCGAAAGCAATGGCGAAAGCCTGCGGCAGGGCGTGATGAACCTGCTCAGCGACATGCAGCGCGGCAAGATTTCGCAGAC
GGACGAGTCGCGCTTCGGCGTCGGCAAGAATCTCGCGATGACGGAAGGTTCCGTCGTATTCGAGAACGAGCTGATGCAGC
TGATCCAGTACACGCCGCGCACGGCGACCGTGCACGAACGTCCGCTGCTGATCGTGCCGCCTTGCATCAACAAGTATTAC
ATCCTGGATCTTCAGCCCGAGAACTCGCTGGTTGCACATGCGCTCGACTCGGGGCATCAGGTGTTTCTGATTTCGTGGCG
CAACGCAGACCAGTCGATCGCCCACAAAACATGGGACGATTACATCGCCGACGGCGTGCTGGCTGCCATCGACACCACGC
GTCAGATCAGCGGACGCGAGCAGATCAATACGCTGGGCTTCTGCATCGGTGGCACGCTGCTCGCAACGGCGCTGTCCGTC
GCCGCGGCGCGCGGCGAGCATCCCGCTGCGTCGATGACGCTGCTCACCGCGATGCTCGACTTCGCCGACACAGGCGTGCT
CGACATCTTCGTCGACGAAGCGCATGTGCAGATGCGCGAGCAGACCATCGGCGGCAAGAACGGTACGCCTCCCGGGCTCA
TGCGCGGCATCGAGTTCGCGAACACATTCTCGTTCCTGCGTCCGAACGACCTTGTGTGGAACTACGTCGTCGACAACTAT
CTAAAGGGCCGCACGCCGATGCCGTTCGACCTGCTGTACTGGAACAGCGACTCGACGAGCCTGCCCGGTCCGATGTACGT
CTGGTATCTGCGCAACACCTACCTCGACAACAAGTTGCGCCAGCCGGGCGCGCTGACCACTTGCGGCGAGAAGGTGGATC
TGTCGCGCATCGACGTGCCGACGTTCATCTACGGTTCGCGTGAAGACCACATCGTGCCGTGGCAATCGGCGTATGCGTCG
GTGCCGCTGTTGACGGGCCCGCGCAAGTTCGTGTTGGGCGCGTCGGGTCATATTGCCGGTGTGATCAATCCGCCGTCGAA
GAACAAGCGCAGTTACTGGTCGGTAGAAGGCGACGACAAGGCGCTGCCTGAGCATCCCGACGACTGGTTCGACACCGCGA
CGGAAACGCCTGGCAGCTGGTGGCCCGAGTGGACGAAGTGGCTCGCACAGTACGGCGGCAAGAAGGTGAAGCCGGCAGCG
AAAGCAGGTTCGGCCGAGTTCCCGGTGATCGAGCCCGCGCCTGGCCGTTACGTGCAACAGCGCGAATAA

Upstream 100 bases:

>100_bases
CCACTGGGCAAGGACGTAACGCGGTCGCGATGCAGTGCTGTTCCCGCGCAAGTACCTGCCTCTCAACCCGTCCGCGAGGA
CTTTTCGGTCAAAAGCAGGC

Downstream 100 bases:

>100_bases
GCGTCGCGCGGCGGGTTGGATGATTCGCGAGTGGTCGCCGGTGAAGCGCAATGAGCAACCGCCGCCAACGAACACCGGGT
GAAGATGGATGGAGTGAGAC

Product: poly(R)-hydroxyalkanoic acid synthase, class I

Products: NA

Alternate protein names: PHA synthase; PHB synthase; Poly(3-hydroxyalkanoate) polymerase; PHA polymerase; Poly(3-hydroxybutyrate) polymerase; PHB polymerase; Polyhydroxyalkanoic acid synthase [H]

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MAASHTSSTSSRTDTSSDRTQQQANAAGVHQWFDAWMNAWRSLGAQAAANGNPFSVPSMPDFAKAATAQAGSLPFSNPLF
EQIAKQFAQTPGQPNGEAAGQPFNALFGPAFNPQFAQQFTQQIAGLKMPSASIPPNRLQQLQSDYSREAMQLLQQAAQAT
ASGIELKDRRFSSEAWKTTPIYTHTAAWYLLNARYLQELVDAIETDQKTRERIRFAVQQWTAAASPSNFFALNPEAQKTL
LESNGESLRQGVMNLLSDMQRGKISQTDESRFGVGKNLAMTEGSVVFENELMQLIQYTPRTATVHERPLLIVPPCINKYY
ILDLQPENSLVAHALDSGHQVFLISWRNADQSIAHKTWDDYIADGVLAAIDTTRQISGREQINTLGFCIGGTLLATALSV
AAARGEHPAASMTLLTAMLDFADTGVLDIFVDEAHVQMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNY
LKGRTPMPFDLLYWNSDSTSLPGPMYVWYLRNTYLDNKLRQPGALTTCGEKVDLSRIDVPTFIYGSREDHIVPWQSAYAS
VPLLTGPRKFVLGASGHIAGVINPPSKNKRSYWSVEGDDKALPEHPDDWFDTATETPGSWWPEWTKWLAQYGGKKVKPAA
KAGSAEFPVIEPAPGRYVQQRE

Sequences:

>Translated_662_residues
MAASHTSSTSSRTDTSSDRTQQQANAAGVHQWFDAWMNAWRSLGAQAAANGNPFSVPSMPDFAKAATAQAGSLPFSNPLF
EQIAKQFAQTPGQPNGEAAGQPFNALFGPAFNPQFAQQFTQQIAGLKMPSASIPPNRLQQLQSDYSREAMQLLQQAAQAT
ASGIELKDRRFSSEAWKTTPIYTHTAAWYLLNARYLQELVDAIETDQKTRERIRFAVQQWTAAASPSNFFALNPEAQKTL
LESNGESLRQGVMNLLSDMQRGKISQTDESRFGVGKNLAMTEGSVVFENELMQLIQYTPRTATVHERPLLIVPPCINKYY
ILDLQPENSLVAHALDSGHQVFLISWRNADQSIAHKTWDDYIADGVLAAIDTTRQISGREQINTLGFCIGGTLLATALSV
AAARGEHPAASMTLLTAMLDFADTGVLDIFVDEAHVQMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNY
LKGRTPMPFDLLYWNSDSTSLPGPMYVWYLRNTYLDNKLRQPGALTTCGEKVDLSRIDVPTFIYGSREDHIVPWQSAYAS
VPLLTGPRKFVLGASGHIAGVINPPSKNKRSYWSVEGDDKALPEHPDDWFDTATETPGSWWPEWTKWLAQYGGKKVKPAA
KAGSAEFPVIEPAPGRYVQQRE
>Mature_661_residues
AASHTSSTSSRTDTSSDRTQQQANAAGVHQWFDAWMNAWRSLGAQAAANGNPFSVPSMPDFAKAATAQAGSLPFSNPLFE
QIAKQFAQTPGQPNGEAAGQPFNALFGPAFNPQFAQQFTQQIAGLKMPSASIPPNRLQQLQSDYSREAMQLLQQAAQATA
SGIELKDRRFSSEAWKTTPIYTHTAAWYLLNARYLQELVDAIETDQKTRERIRFAVQQWTAAASPSNFFALNPEAQKTLL
ESNGESLRQGVMNLLSDMQRGKISQTDESRFGVGKNLAMTEGSVVFENELMQLIQYTPRTATVHERPLLIVPPCINKYYI
LDLQPENSLVAHALDSGHQVFLISWRNADQSIAHKTWDDYIADGVLAAIDTTRQISGREQINTLGFCIGGTLLATALSVA
AARGEHPAASMTLLTAMLDFADTGVLDIFVDEAHVQMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNYL
KGRTPMPFDLLYWNSDSTSLPGPMYVWYLRNTYLDNKLRQPGALTTCGEKVDLSRIDVPTFIYGSREDHIVPWQSAYASV
PLLTGPRKFVLGASGHIAGVINPPSKNKRSYWSVEGDDKALPEHPDDWFDTATETPGSWWPEWTKWLAQYGGKKVKPAAK
AGSAEFPVIEPAPGRYVQQRE

Specific function: Polymerizes d(-)-3-hydroxybutyryl-CoA to create PHB which consists of thousands of hydroxybutyrate molecules linked end to end. PHB serves as an intracellular energy reserve material when cells grow under conditions of nutrient limitation [H]

COG id: COG3243

COG function: function code I; Poly(3-hydroxyalkanoate) synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHA/PHB synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR010963
- InterPro:   IPR010941 [H]

Pfam domain/function: PF00561 Abhydrolase_1; PF07167 PhaC_N [H]

EC number: NA

Molecular weight: Translated: 73192; Mature: 73061

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASHTSSTSSRTDTSSDRTQQQANAAGVHQWFDAWMNAWRSLGAQAAANGNPFSVPSMP
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCC
DFAKAATAQAGSLPFSNPLFEQIAKQFAQTPGQPNGEAAGQPFNALFGPAFNPQFAQQFT
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHH
QQIAGLKMPSASIPPNRLQQLQSDYSREAMQLLQQAAQATASGIELKDRRFSSEAWKTTP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
IYTHTAAWYLLNARYLQELVDAIETDQKTRERIRFAVQQWTAAASPSNFFALNPEAQKTL
CEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHH
LESNGESLRQGVMNLLSDMQRGKISQTDESRFGVGKNLAMTEGSVVFENELMQLIQYTPR
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCEEECCCCEEEHHHHHHHHHCCCC
TATVHERPLLIVPPCINKYYILDLQPENSLVAHALDSGHQVFLISWRNADQSIAHKTWDD
CCEECCCCEEEECCCCCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCHHHHHHHHHH
YIADGVLAAIDTTRQISGREQINTLGFCIGGTLLATALSVAAARGEHPAASMTLLTAMLD
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FADTGVLDIFVDEAHVQMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNY
HHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LKGRTPMPFDLLYWNSDSTSLPGPMYVWYLRNTYLDNKLRQPGALTTCGEKVDLSRIDVP
HCCCCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
TFIYGSREDHIVPWQSAYASVPLLTGPRKFVLGASGHIAGVINPPSKNKRSYWSVEGDDK
EEEECCCCCCCCCHHHHHCCCCEECCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCCC
ALPEHPDDWFDTATETPGSWWPEWTKWLAQYGGKKVKPAAKAGSAEFPVIEPAPGRYVQQ
CCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCEECCCCCCCCCC
RE
CC
>Mature Secondary Structure 
AASHTSSTSSRTDTSSDRTQQQANAAGVHQWFDAWMNAWRSLGAQAAANGNPFSVPSMP
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCC
DFAKAATAQAGSLPFSNPLFEQIAKQFAQTPGQPNGEAAGQPFNALFGPAFNPQFAQQFT
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHH
QQIAGLKMPSASIPPNRLQQLQSDYSREAMQLLQQAAQATASGIELKDRRFSSEAWKTTP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCC
IYTHTAAWYLLNARYLQELVDAIETDQKTRERIRFAVQQWTAAASPSNFFALNPEAQKTL
CEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHH
LESNGESLRQGVMNLLSDMQRGKISQTDESRFGVGKNLAMTEGSVVFENELMQLIQYTPR
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCEEECCCCEEEHHHHHHHHHCCCC
TATVHERPLLIVPPCINKYYILDLQPENSLVAHALDSGHQVFLISWRNADQSIAHKTWDD
CCEECCCCEEEECCCCCCEEEEEECCCCCHHHHHHCCCCEEEEEEECCCCHHHHHHHHHH
YIADGVLAAIDTTRQISGREQINTLGFCIGGTLLATALSVAAARGEHPAASMTLLTAMLD
HHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
FADTGVLDIFVDEAHVQMREQTIGGKNGTPPGLMRGIEFANTFSFLRPNDLVWNYVVDNY
HHCCCEEEEEECHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LKGRTPMPFDLLYWNSDSTSLPGPMYVWYLRNTYLDNKLRQPGALTTCGEKVDLSRIDVP
HCCCCCCCEEEEEECCCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
TFIYGSREDHIVPWQSAYASVPLLTGPRKFVLGASGHIAGVINPPSKNKRSYWSVEGDDK
EEEECCCCCCCCCHHHHHCCCCEECCCCEEEEECCCCEEEEECCCCCCCCCEEEECCCCC
ALPEHPDDWFDTATETPGSWWPEWTKWLAQYGGKKVKPAAKAGSAEFPVIEPAPGRYVQQ
CCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCCCCCCEECCCCCCCCCC
RE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670936; 1987116 [H]