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The map label for this gene is pncB [H]

Identifier: 186475573

GI number: 186475573

Start: 906133

End: 907332

Strand: Direct

Name: pncB [H]

Synonym: Bphy_0808

Alternate gene names: 186475573

Gene position: 906133-907332 (Clockwise)

Preceding gene: 186475566

Following gene: 186475574

Centisome position: 26.04

GC content: 59.92

Gene sequence:

>1200_bases
ATGATCATTACATCGCTGTTCGATACCGACCTGTACAAGTTCACGATGATGCAGGTCGTGCTGCATCATTTCCCGGCCGC
CAATGTCGAATACAAGTTCCGCTGCCGTACGCCGAAAGTCAACCTCGTGCCGTACATCGACGAAATACGCAGCGAAGTGC
ACAAGCTCTGCAAGCTGCGCTTCAGCGAGGGCGAACTCGACTATTTGCGCCGGATGCGCTTCATCAAGAACGACTTCATC
GATTTCCTCGCGCTCTTCCATCTGAACGAGAAGTACATCTCCATTACGCCGTCGGCGAAAGGCAACGGCGAGATCGAGAT
CGACATCAAGGGGCCGTGGCTGCACACGATCCTCTTCGAAATCCCCGTGCTCGCGATCGTCAACGAAGTCTATTTCCGCA
ACACGCAGCAGCAGCCCGATTACAGCGAAGGGCGCGAGCGCCTGCGCGACAAGATCCAGTTGCTAGGCGCGCGCCCCGAG
TTCGCCGAATGCAAGATCGCCGACTACGGCACGCGCCGCCGCTTCTCGGGCCGCTGGCACGAAGAGGTGATCCTCACGCT
CAAGGACGGCCTGCGCGAGCAGTTCGCCGGCACCAGCAACGTGTTTTATGCGATGAAGCACGGACTCACGCCGCTCGGCA
CGATGGCGCATGAGTACCTGCAGGCCTGCCAGGCACTGGGCCCGCGCCTGCGCGATTCGCAGATCTTCGGGTTCGAAATG
TGGGCGAAGGAATATCGCGGCGACCTGGGCATCGCTTTGTCGGACGTCTATGGCATGAAGGCGTTCCTGCGTGATTTCGA
CATGTACTTCTGCAAGCTGTTCGACGGCGCGCGTCACGATTCCGGCGACCCGTTCGACTGGGGCGAGCGGCTTCTCGCGC
ACTACGAAGCGAACCGCTGCGATCCGCGCACGAAGGTGCTCGTGTTCTCCGACGCGCTCGACATTCCGAAAGTGCTGCAG
TTGTACGAGCGCTTCCGTGGCCGCTGCAAGCTGGCATTCGGCGTGGGCACGAACCTGACCAACGATCTCGGCTATAACCC
GCTGCAGATCGTGATCAAGATGGTCAAGTGCAACGGCCAGCCCGTCGCGAAGCTGTCGGACTCGCCGGGCAAGAACATGT
GCGAAGACAAGGCGTACCTCGCCTATCTGCGCCAGGTGTTCGGCATCGAGCAGCCTGAAGAAGAAGCCGCAGGCAAATAA

Upstream 100 bases:

>100_bases
CTCGCGCATTGGAACGACTGCCGGCGCGCATTCGGGTAACATGCGACAGCATCTTCGCGAGACGTCTTCCGATTCTCATG
CAGTTCCGGTTTGCAAGATC

Downstream 100 bases:

>100_bases
CGCCCCGCATGCCTTTCACAGGTGTCGCAGCGCATGTGAAGATCATTTTCGATGCTTCGCGCAAGCGCCGCTATAGACCG
TCCGGCTTGGGCGATACACT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MIITSLFDTDLYKFTMMQVVLHHFPAANVEYKFRCRTPKVNLVPYIDEIRSEVHKLCKLRFSEGELDYLRRMRFIKNDFI
DFLALFHLNEKYISITPSAKGNGEIEIDIKGPWLHTILFEIPVLAIVNEVYFRNTQQQPDYSEGRERLRDKIQLLGARPE
FAECKIADYGTRRRFSGRWHEEVILTLKDGLREQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQIFGFEM
WAKEYRGDLGIALSDVYGMKAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLAHYEANRCDPRTKVLVFSDALDIPKVLQ
LYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVKCNGQPVAKLSDSPGKNMCEDKAYLAYLRQVFGIEQPEEEAAGK

Sequences:

>Translated_399_residues
MIITSLFDTDLYKFTMMQVVLHHFPAANVEYKFRCRTPKVNLVPYIDEIRSEVHKLCKLRFSEGELDYLRRMRFIKNDFI
DFLALFHLNEKYISITPSAKGNGEIEIDIKGPWLHTILFEIPVLAIVNEVYFRNTQQQPDYSEGRERLRDKIQLLGARPE
FAECKIADYGTRRRFSGRWHEEVILTLKDGLREQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQIFGFEM
WAKEYRGDLGIALSDVYGMKAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLAHYEANRCDPRTKVLVFSDALDIPKVLQ
LYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVKCNGQPVAKLSDSPGKNMCEDKAYLAYLRQVFGIEQPEEEAAGK
>Mature_399_residues
MIITSLFDTDLYKFTMMQVVLHHFPAANVEYKFRCRTPKVNLVPYIDEIRSEVHKLCKLRFSEGELDYLRRMRFIKNDFI
DFLALFHLNEKYISITPSAKGNGEIEIDIKGPWLHTILFEIPVLAIVNEVYFRNTQQQPDYSEGRERLRDKIQLLGARPE
FAECKIADYGTRRRFSGRWHEEVILTLKDGLREQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQIFGFEM
WAKEYRGDLGIALSDVYGMKAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLAHYEANRCDPRTKVLVFSDALDIPKVLQ
LYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVKCNGQPVAKLSDSPGKNMCEDKAYLAYLRQVFGIEQPEEEAAGK

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=392, Percent_Identity=42.6020408163265, Blast_Score=325, Evalue=4e-90,
Organism=Saccharomyces cerevisiae, GI6324783, Length=414, Percent_Identity=28.9855072463768, Blast_Score=191, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 46173; Mature: 46173

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIITSLFDTDLYKFTMMQVVLHHFPAANVEYKFRCRTPKVNLVPYIDEIRSEVHKLCKLR
CEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
FSEGELDYLRRMRFIKNDFIDFLALFHLNEKYISITPSAKGNGEIEIDIKGPWLHTILFE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHH
IPVLAIVNEVYFRNTQQQPDYSEGRERLRDKIQLLGARPEFAECKIADYGTRRRFSGRWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCHH
EEVILTLKDGLREQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQIFGFEM
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMKAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLAHYEANRC
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVKCNGQ
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
PVAKLSDSPGKNMCEDKAYLAYLRQVFGIEQPEEEAAGK
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCC
>Mature Secondary Structure
MIITSLFDTDLYKFTMMQVVLHHFPAANVEYKFRCRTPKVNLVPYIDEIRSEVHKLCKLR
CEECCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHC
FSEGELDYLRRMRFIKNDFIDFLALFHLNEKYISITPSAKGNGEIEIDIKGPWLHTILFE
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCHHHHHHHH
IPVLAIVNEVYFRNTQQQPDYSEGRERLRDKIQLLGARPEFAECKIADYGTRRRFSGRWH
HHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCCHH
EEVILTLKDGLREQFAGTSNVFYAMKHGLTPLGTMAHEYLQACQALGPRLRDSQIFGFEM
HHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WAKEYRGDLGIALSDVYGMKAFLRDFDMYFCKLFDGARHDSGDPFDWGERLLAHYEANRC
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
DPRTKVLVFSDALDIPKVLQLYERFRGRCKLAFGVGTNLTNDLGYNPLQIVIKMVKCNGQ
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCC
PVAKLSDSPGKNMCEDKAYLAYLRQVFGIEQPEEEAAGK
CCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA