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The map label for this gene is zraR [H]

Identifier: 186475552

GI number: 186475552

Start: 882947

End: 884341

Strand: Direct

Name: zraR [H]

Synonym: Bphy_0787

Alternate gene names: 186475552

Gene position: 882947-884341 (Clockwise)

Preceding gene: 186475546

Following gene: 186475553

Centisome position: 25.38

GC content: 65.23

Gene sequence:

>1395_bases
ATGGAATCCGCCACGCGGCAACTGATTTACGTATCAAGAGATCCCAGCGCTGAGTTGAACACGCGCTTTCATGAGCGCGG
GTGGCATGTCGAGGTCGTCGGCTCAGCTCGCGACGCCCGACGCGCCGTGCGCTCGGGGATGGCGGCGGGCGGCCTGCTCG
ATCTGTCGAGCTGTTTCCAGCAGCACGAAATCGCGGCCTTCGAATCGTGCCTGACCATGCCCAACGTCGGCTGGGTCGCC
ACCACGATGGCCGGCCAGCTGCAGGACGCTGCATTGCGCCGGCTCGTGCGCGATTACTGTTTCGATTACGTGACCGTGCC
TTATTCGGGCGACCGCATCGTCGATTCCGTCGGCCATGCTTACGGCATGGTGTCGCTCGGCGAGCCTGCATCGAACGATG
CGTCGCAAGGCGGCTCGGAAGGCGAAATGGTCGGCTCGTGCGACGCGATGCTCGCGCTGTTCCGTTCTATCCGCAAAGTG
GCGATGACGGACGCCCCCGTGTTCATCTCGGGTGAATCCGGCACGGGCAAGGAACTCACGGCCGTCGCCATTCACGAGCG
CTCGTCGCGCCGCAATGCGCCGTTCATCCCCATCAACTGCGGGGCGATTCCGCCGCATCTGCTGCAATCGGAACTGTTCG
GCTACGAGCGCGGGGCCTTCACAGGCGCCAACCAGCGCAAGATCGGCCGCGTCGAAGCGGCGAACGGCGGCACGCTGTTC
CTCGATGAAATCGGCGACCTGCCGCTCGAAAGCCAGGCGAGCCTGCTGCGCTTCCTGCAGGAGCGCAAGGTCGAGCGGCT
GGGCGGGCACGGCTCGATCGAGGTGGACGTGCGGATCATTTCGGCGACACACGTCGACATGAACACGGCGATGATCGAAG
GCCGCTTCCGCTCGGACCTCTATCATCGGCTTTGCGTGCTGCAGATCGATGAGCCGCCGCTGCGCGCGCGCGGCAAGGAC
ATCGAACTGCTTGCGCGGCATATGCTCGAACGTTTCAGGAAAGACGCCAGCCGTCGGCTGCGCGGCTTTGCGCCCGACGC
GATTGCGGCGCTCCACAACTACAGCTGGCCGGGTAACGTGCGAGAACTGATCAACCGCGTGCGGCGGGCGATCGTGATGT
CGGAAGGGCGGGCCATCACGGCGCGCGATCTCGAACTGGCCGAATACGTGGAGATCGTCCCTGTGTCGCTGGCACAGGCG
CGCGAGGCGGCCGAGCGGCAGGCGATCGAGCTGGCCTTGTTGCGTCATCGCGGGCGTCTCGGCGACGCGGCACAGGAACT
CGGGATTTCGCGCGTGACGCTGTACCGGCTGTTGTGCTCGCACGGTATGCGGCATATGGAAAGCGAGCCGCTCGCGCAAC
ACGCGGACATGCCGTCGACGATGCCGCATCTGTAA

Upstream 100 bases:

>100_bases
CGCTGTTTGCGAATCCCGTGCGAATAGGCGTGCCTGAAAGCTAAATCCAGATCAGCACATGCCGTCATCCTTAACGTTCG
TTGACGAGAGGATCTGAATA

Downstream 100 bases:

>100_bases
AGCGGCGGGGCGCTGCCCCCCTGCGTGCGAGACTGTCATCGCGAATGAAGCCCGGCCGGCTGGCCGGGCTTTCCTTTCTG
CAGCGTCGCAGCGCGGGTGG

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MESATRQLIYVSRDPSAELNTRFHERGWHVEVVGSARDARRAVRSGMAAGGLLDLSSCFQQHEIAAFESCLTMPNVGWVA
TTMAGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHAYGMVSLGEPASNDASQGGSEGEMVGSCDAMLALFRSIRKV
AMTDAPVFISGESGTGKELTAVAIHERSSRRNAPFIPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQERKVERLGGHGSIEVDVRIISATHVDMNTAMIEGRFRSDLYHRLCVLQIDEPPLRARGKD
IELLARHMLERFRKDASRRLRGFAPDAIAALHNYSWPGNVRELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQA
REAAERQAIELALLRHRGRLGDAAQELGISRVTLYRLLCSHGMRHMESEPLAQHADMPSTMPHL

Sequences:

>Translated_464_residues
MESATRQLIYVSRDPSAELNTRFHERGWHVEVVGSARDARRAVRSGMAAGGLLDLSSCFQQHEIAAFESCLTMPNVGWVA
TTMAGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHAYGMVSLGEPASNDASQGGSEGEMVGSCDAMLALFRSIRKV
AMTDAPVFISGESGTGKELTAVAIHERSSRRNAPFIPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQERKVERLGGHGSIEVDVRIISATHVDMNTAMIEGRFRSDLYHRLCVLQIDEPPLRARGKD
IELLARHMLERFRKDASRRLRGFAPDAIAALHNYSWPGNVRELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQA
REAAERQAIELALLRHRGRLGDAAQELGISRVTLYRLLCSHGMRHMESEPLAQHADMPSTMPHL
>Mature_464_residues
MESATRQLIYVSRDPSAELNTRFHERGWHVEVVGSARDARRAVRSGMAAGGLLDLSSCFQQHEIAAFESCLTMPNVGWVA
TTMAGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHAYGMVSLGEPASNDASQGGSEGEMVGSCDAMLALFRSIRKV
AMTDAPVFISGESGTGKELTAVAIHERSSRRNAPFIPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLF
LDEIGDLPLESQASLLRFLQERKVERLGGHGSIEVDVRIISATHVDMNTAMIEGRFRSDLYHRLCVLQIDEPPLRARGKD
IELLARHMLERFRKDASRRLRGFAPDAIAALHNYSWPGNVRELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQA
REAAERQAIELALLRHRGRLGDAAQELGISRVTLYRLLCSHGMRHMESEPLAQHADMPSTMPHL

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=424, Percent_Identity=40.8018867924528, Blast_Score=268, Evalue=6e-73,
Organism=Escherichia coli, GI1788550, Length=357, Percent_Identity=42.8571428571429, Blast_Score=266, Evalue=2e-72,
Organism=Escherichia coli, GI1790299, Length=372, Percent_Identity=40.5913978494624, Blast_Score=249, Evalue=2e-67,
Organism=Escherichia coli, GI1788905, Length=371, Percent_Identity=39.622641509434, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI87082117, Length=283, Percent_Identity=44.8763250883392, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1789233, Length=313, Percent_Identity=44.7284345047923, Blast_Score=242, Evalue=4e-65,
Organism=Escherichia coli, GI1789087, Length=300, Percent_Identity=42.6666666666667, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082152, Length=335, Percent_Identity=39.7014925373134, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1786524, Length=319, Percent_Identity=42.6332288401254, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=36.3924050632911, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1787583, Length=335, Percent_Identity=34.3283582089552, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI87081858, Length=293, Percent_Identity=32.7645051194539, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789828, Length=242, Percent_Identity=34.297520661157, Blast_Score=127, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 51249; Mature: 51249

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESATRQLIYVSRDPSAELNTRFHERGWHVEVVGSARDARRAVRSGMAAGGLLDLSSCFQ
CCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHH
QHEIAAFESCLTMPNVGWVATTMAGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHH
YGMVSLGEPASNDASQGGSEGEMVGSCDAMLALFRSIRKVAMTDAPVFISGESGTGKELT
HCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEE
AVAIHERSSRRNAPFIPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQERKVERLGGHGSIEVDVRIISATHVDMNTAMIEGRFRSDL
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCHHHHCCCHHHHHH
YHRLCVLQIDEPPLRARGKDIELLARHMLERFRKDASRRLRGFAPDAIAALHNYSWPGNV
HHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAREAAERQAIELALLRHRGRL
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDAAQELGISRVTLYRLLCSHGMRHMESEPLAQHADMPSTMPHL
CHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCC
>Mature Secondary Structure
MESATRQLIYVSRDPSAELNTRFHERGWHVEVVGSARDARRAVRSGMAAGGLLDLSSCFQ
CCCCCCEEEEEECCCCCHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHH
QHEIAAFESCLTMPNVGWVATTMAGQLQDAALRRLVRDYCFDYVTVPYSGDRIVDSVGHA
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHH
YGMVSLGEPASNDASQGGSEGEMVGSCDAMLALFRSIRKVAMTDAPVFISGESGTGKELT
HCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEE
AVAIHERSSRRNAPFIPINCGAIPPHLLQSELFGYERGAFTGANQRKIGRVEAANGGTLF
EEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEE
LDEIGDLPLESQASLLRFLQERKVERLGGHGSIEVDVRIISATHVDMNTAMIEGRFRSDL
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEEECCHHHHCCCHHHHHH
YHRLCVLQIDEPPLRARGKDIELLARHMLERFRKDASRRLRGFAPDAIAALHNYSWPGNV
HHCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCHH
RELINRVRRAIVMSEGRAITARDLELAEYVEIVPVSLAQAREAAERQAIELALLRHRGRL
HHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GDAAQELGISRVTLYRLLCSHGMRHMESEPLAQHADMPSTMPHL
CHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11243806 [H]