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The map label for this gene is 186475521

Identifier: 186475521

GI number: 186475521

Start: 852859

End: 853782

Strand: Direct

Name: 186475521

Synonym: Bphy_0756

Alternate gene names: NA

Gene position: 852859-853782 (Clockwise)

Preceding gene: 186475519

Following gene: 186475522

Centisome position: 24.51

GC content: 63.64

Gene sequence:

>924_bases
ATGGCAACCGGTTTCTATTCACATGCAGACTGTCTGCAGCATGAGATGGGTCAATGGCATCCCGAATGCCCGGCCCGGCT
GCAGGCAATCGAAGACCAGTTGATCGCAAGCCGCATCGGCGAGCTGATCGAGCGCGAGTCCGCACCGCTTGCCGACGAAG
CCGCGCTGTTGCGCGTGCATACGAAGGCGCACGTCGACTACCTCCGCGCACGCTCGCCGCAGAGCGGCTACGCTGAGATC
GACCCCGATACGTCGATGAACCCGCACACGTGGACGGCCGCGTTGCGCGCAGCGGGGGCAGCCGTCGCGGCCACCGACGC
CGTGATCGAAGGCCGCTACGACAACGCGTTTTGCAGCGTGCGCCCGCCGGGCCATCATGCCGAGCCTGCACGCGCCATGG
GTTTCTGTTTCTTCAACAATGTCGCGATCGCCGCGCGGCATGCGCTCGAGGTGCATAAGCTGGAGCGCGTGGCGATCATC
GATTTCGACGTGCATCATGGCAATGGCACGGAGGCCGCGTTTTCGAACGACGCGCGCGTGCTGATGTGCAGCATCTTCCA
GCACCCGTTCTATCCGTTCACGGGTGCCGACAACCAGGCACCGAACATGTGCAACGTGCCGATCGCGGCACGCTCGAAAG
GCATGGTCGTGCGCGAAGCCATCGACATGATCTGGCTGCCTCGACTCGACGCATTCAAGCCGCAGATGCTGTTCGTGTCG
GCAGGCTTCGACGCGCACCGTGAGGACGATCTTGGCAACATGGCGCTCGTCGAGGACGACTATGCGTGGATCACACAGCA
GATCCGCCTGGTCGCCGACAAGTATGCGAAAGGGCGCATCGTCAGCTGCCTGGAAGGCGGCTACAACCTGTCGGCGCTCG
GACGCAGCGTCGTCGCGCACGTAAGGGCGCTCGCGGATATCTGA

Upstream 100 bases:

>100_bases
GTAACTTCGTAGTATTCGCGCAACCCGCTTGCGTCAATGGACGGAGACATGCAGCGCAGGCTCGCCATGCCGTGCGAGGC
GCGCAGCTGAAAATCAACTC

Downstream 100 bases:

>100_bases
GCGCGAGGGCGTGCATCGCAGGAGGCGGCATCATGAATGCAGAGGCGACAGGCGCACTGATCGAACGCACGCGAGACGCG
TATGACCTCGGCGGGGTGGT

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MATGFYSHADCLQHEMGQWHPECPARLQAIEDQLIASRIGELIERESAPLADEAALLRVHTKAHVDYLRARSPQSGYAEI
DPDTSMNPHTWTAALRAAGAAVAATDAVIEGRYDNAFCSVRPPGHHAEPARAMGFCFFNNVAIAARHALEVHKLERVAII
DFDVHHGNGTEAAFSNDARVLMCSIFQHPFYPFTGADNQAPNMCNVPIAARSKGMVVREAIDMIWLPRLDAFKPQMLFVS
AGFDAHREDDLGNMALVEDDYAWITQQIRLVADKYAKGRIVSCLEGGYNLSALGRSVVAHVRALADI

Sequences:

>Translated_307_residues
MATGFYSHADCLQHEMGQWHPECPARLQAIEDQLIASRIGELIERESAPLADEAALLRVHTKAHVDYLRARSPQSGYAEI
DPDTSMNPHTWTAALRAAGAAVAATDAVIEGRYDNAFCSVRPPGHHAEPARAMGFCFFNNVAIAARHALEVHKLERVAII
DFDVHHGNGTEAAFSNDARVLMCSIFQHPFYPFTGADNQAPNMCNVPIAARSKGMVVREAIDMIWLPRLDAFKPQMLFVS
AGFDAHREDDLGNMALVEDDYAWITQQIRLVADKYAKGRIVSCLEGGYNLSALGRSVVAHVRALADI
>Mature_306_residues
ATGFYSHADCLQHEMGQWHPECPARLQAIEDQLIASRIGELIERESAPLADEAALLRVHTKAHVDYLRARSPQSGYAEID
PDTSMNPHTWTAALRAAGAAVAATDAVIEGRYDNAFCSVRPPGHHAEPARAMGFCFFNNVAIAARHALEVHKLERVAIID
FDVHHGNGTEAAFSNDARVLMCSIFQHPFYPFTGADNQAPNMCNVPIAARSKGMVVREAIDMIWLPRLDAFKPQMLFVSA
GFDAHREDDLGNMALVEDDYAWITQQIRLVADKYAKGRIVSCLEGGYNLSALGRSVVAHVRALADI

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI13128864, Length=303, Percent_Identity=33.993399339934, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI20070354, Length=326, Percent_Identity=34.3558282208589, Blast_Score=151, Evalue=8e-37,
Organism=Homo sapiens, GI17158039, Length=324, Percent_Identity=32.7160493827161, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI30795202, Length=324, Percent_Identity=32.7160493827161, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI30795204, Length=324, Percent_Identity=32.7160493827161, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI62750347, Length=327, Percent_Identity=31.8042813455657, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI62750349, Length=327, Percent_Identity=31.8042813455657, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI226529806, Length=318, Percent_Identity=31.7610062893082, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI148539870, Length=324, Percent_Identity=33.0246913580247, Blast_Score=124, Evalue=7e-29,
Organism=Homo sapiens, GI169234807, Length=245, Percent_Identity=36.734693877551, Blast_Score=124, Evalue=8e-29,
Organism=Homo sapiens, GI153085395, Length=323, Percent_Identity=31.8885448916409, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI13128860, Length=286, Percent_Identity=24.1258741258741, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI293336691, Length=286, Percent_Identity=24.1258741258741, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI13128862, Length=275, Percent_Identity=22.9090909090909, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=33.7662337662338, Blast_Score=160, Evalue=7e-40,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=33.7662337662338, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=33.7662337662338, Blast_Score=159, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193209491, Length=324, Percent_Identity=34.8765432098765, Blast_Score=155, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25154020, Length=300, Percent_Identity=30.6666666666667, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17537347, Length=308, Percent_Identity=33.7662337662338, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25154022, Length=300, Percent_Identity=30.3333333333333, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17534739, Length=310, Percent_Identity=25.8064516129032, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17508561, Length=283, Percent_Identity=24.7349823321555, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17561978, Length=268, Percent_Identity=23.134328358209, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324307, Length=317, Percent_Identity=31.8611987381703, Blast_Score=155, Evalue=9e-39,
Organism=Saccharomyces cerevisiae, GI6323999, Length=285, Percent_Identity=23.859649122807, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321244, Length=267, Percent_Identity=28.4644194756554, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325325, Length=176, Percent_Identity=26.7045454545455, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325141, Length=94, Percent_Identity=32.9787234042553, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281360899, Length=306, Percent_Identity=37.5816993464052, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24642142, Length=306, Percent_Identity=37.5816993464052, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24642146, Length=306, Percent_Identity=37.5816993464052, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24642144, Length=306, Percent_Identity=37.5816993464052, Blast_Score=174, Evalue=7e-44,
Organism=Drosophila melanogaster, GI281360801, Length=324, Percent_Identity=33.9506172839506, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI281360799, Length=324, Percent_Identity=33.9506172839506, Blast_Score=137, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24641720, Length=324, Percent_Identity=33.9506172839506, Blast_Score=137, Evalue=8e-33,
Organism=Drosophila melanogaster, GI24657891, Length=275, Percent_Identity=26.5454545454545, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644244, Length=333, Percent_Identity=23.4234234234234, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24649807, Length=244, Percent_Identity=25.8196721311475, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 33762; Mature: 33630

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGFYSHADCLQHEMGQWHPECPARLQAIEDQLIASRIGELIERESAPLADEAALLRVH
CCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
TKAHVDYLRARSPQSGYAEIDPDTSMNPHTWTAALRAAGAAVAATDAVIEGRYDNAFCSV
HHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHEECCCCCCEEEE
RPPGHHAEPARAMGFCFFNNVAIAARHALEVHKLERVAIIDFDVHHGNGTEAAFSNDARV
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCHH
LMCSIFQHPFYPFTGADNQAPNMCNVPIAARSKGMVVREAIDMIWLPRLDAFKPQMLFVS
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDLGNMALVEDDYAWITQQIRLVADKYAKGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHH
VRALADI
HHHHHCC
>Mature Secondary Structure 
ATGFYSHADCLQHEMGQWHPECPARLQAIEDQLIASRIGELIERESAPLADEAALLRVH
CCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
TKAHVDYLRARSPQSGYAEIDPDTSMNPHTWTAALRAAGAAVAATDAVIEGRYDNAFCSV
HHHHHHHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHEECCCCCCEEEE
RPPGHHAEPARAMGFCFFNNVAIAARHALEVHKLERVAIIDFDVHHGNGTEAAFSNDARV
CCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCCCCCHH
LMCSIFQHPFYPFTGADNQAPNMCNVPIAARSKGMVVREAIDMIWLPRLDAFKPQMLFVS
HHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHCCCCCCCCCEEEEEE
AGFDAHREDDLGNMALVEDDYAWITQQIRLVADKYAKGRIVSCLEGGYNLSALGRSVVAH
CCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCHHHHHHHHHHH
VRALADI
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]