Click here to switch to the map view.

The map label for this gene is pepN [H]

Identifier: 186475451

GI number: 186475451

Start: 771230

End: 774013

Strand: Reverse

Name: pepN [H]

Synonym: Bphy_0686

Alternate gene names: 186475451

Gene position: 774013-771230 (Counterclockwise)

Preceding gene: 186475453

Following gene: 186475450

Centisome position: 22.25

GC content: 63.58

Gene sequence:

>2784_bases
ATGACCCGATCACCCGGCGCGCTGTCCGTTGTTGCGCTGTATACAACGCGCCGGCTTCGAGCTTATTCCCGAACGCACAT
CATGGCCGATACCGAAACGCCTCAAGTGATCCGCCGCGCCGACTACGCGCCGCCCGCCTTTCTCATCGATACCGTCGCGC
TCGAGTTCGATCTCGTGCCAGAGCGCACAGTCGTCAGGAATACGATGCGGATCCGCCGCAATCCCGACGCGGTGCGCGCC
ACGCATCTCGACCTGATGGGCGAAGATCTGACGTTCGTCGAAGCGTTGCTCGACGGCAAGCCCTACGCCGACGTGCACCC
GCATGAGCACGGTCTGACCGTCGACAACGTGCCCGATTCGTTCGAACTGACGCTGACGGGCATCTGCAACCCCGCCGCGA
ACACGACGCTGTCGGGCCTGTATGTATCGAGCGGCAACTTCTTCACGCAGTGCGAGGCCGAGGGCTTCCGGCGCATCACG
TGGTTCCTCGATCGCCCGGACGTGATGGCAACCTACACGGTCACGCTGCGCGCCGACAAGGCCGCGTATCCGGTGCTGCT
GTCCAACGGCAACCTTCTCGAACAGGGCGAGTTGCCCGACGGCCGTCATTTCGCGCGCTGGGAAGATCCGTTCAGGAAGC
CGAGCTATCTGTTCGCGCTCGTCGCGGGCAAACTCGTTGCGCTGGAAGAGCGCGTGAAGTCCGGTTCGGGCAAGGACAAG
CTGCTGCAGGTCTGGGTCGAGCCGCACGATCTCGACAAGACCCGTCATGCAATGGATTCGCTGATCCATTCCATTCGCTG
GGACGAAGCGCGCTTCGGCCTCGAACTCGACCTGGACCGCTTCATGATCGTCGCCGTGAGCGACTTCAACATGGGCGCGA
TGGAGAACAAAGGGCTCAACATCTTCAACACGAAGTATGTGCTGGCGAACCCCGAAACGGCCACCGATACCGACTTCTCC
AACATCGAAGCCGTGGTCGGCCACGAATACTTCCATAACTGGACGGGTAATCGCGTCACGTGCCGCGACTGGTTTCAACT
GAGCCTGAAGGAAGGGCTGACGGTATTCCGCGATCAGGAGTTTTCCGCGGACATGGCGAGCGGCGGCAGTGCCGGCGAGG
ATCAGGCTGCGCGCGCAACCAAGCGCATCGAAGACGTACGCGTGCTGCGTCAGATGCAGTTCGCCGAAGATGCCGGTCCG
ATGGCGCATCCCGTGCGCCCCGAAAGCTATGTGGAGATCAACAACTTCTACACGATGACGGTCTACGAGAAGGGCTCGGA
AGTCGTGCGGATGTATCAGACGTTGTTCGGACGCGAAGGCTTCCGCCGCGGCATGGATCTTTACTTCAAGCGCCACGACG
GCCAGGCGGTGACCTGCGACGACTTCCGTCACGCGATGGCCGATGCGAACGGCCGCGATCTCACGCAATACGAACGCTGG
TACAGCCAGGCGGGCACGCCGCGCATCAGCGTCGACACGCACTATGACGCCGCGCAGAAGCGCTACACGGTGAAGCTCAA
GCAAGGCTACGGCGACGCGTCGCAGGCTGCACGTGACACGCAGAAAGGCCCGCTGCTGATTCCGGTTGCGATCGGCCTGA
TCGGCGATGACGGCAATGACATGCCGCTGCGTCTCGAAGGCGAAGCAGCGGCGTCGCCCCACAGCACGCGCGTGCTCGAG
TTCACGCAAGCCGAACAGAGCTTTACGTTCGTCGACGTCGCCGAGAAGCCGCTGCCGTCGCTGCTGCGCAATTTTTCGGC
GCCCGTCGTTGTCGAGTACGACTACACGGCCGATGAACTCGCGTTCCTGCTCGCGCACGACAGCGATCCGTTCAACCGCT
GGGAAGCCGGCCAGCGCCTCGCAACGCGCGAGCTGCTCACGCTCGCCGAACACGCAGCAACGGGCAAGGCACTGGAACTG
GACGACACGGTGGTCGCCGCCTTCGGCCGCGTGCTGAACGACGAGACGCTGTCGCCAGCATTCCGCGAACTCACGCTGAT
GCTGCCTTCGGAGGCATATCTCGCCGAGCAGATGGAAGAGTCGAATCCCGCAGCCGTTCACAGCGCGCGGCAGTTCGTGC
GCAAGCGCATGGCATCGGCGCTCAAGGGCGACTGGCTCGCGATCTACGAGCGTCATCAGACGCCCGGCGCTTATGAGCCG
ACGCCCACGGCGGCCGGACATCGTGCGCTGAAGAACCTTGCGCTCGCGTATATCGCCGAACTCGATGATCCAACCGACGC
CAGGCGCCTCGCGAAGGCGCAGTACGACGCGGCAAACAACATGACGGATCGCGCGTCGGCTTTGTCCGCGCTGCTGACGG
CGGGGGTATCGAACGGCGGCGCGGCGGCGGCCGAGGCGCTCGACGACTTCTATCGCCGCTTCGAAGACGAGCCGCTCGTG
ATTGACAAGTGGTTTGCGCTGCAGGCGATGCAACGCGGCACGAAGCAGCGGCCCGTCATCGAGATCGTGCGCACGTTGAT
GACGCATCCAGCGTTCAATCTGAAAAACCCGAATCGCGCGCGCTCGCTGATCTTCAGCTTCTGCTCGGCGAACCCTGCGC
AGTTCCACGCGGAAGACGGCTCAGGCTATGCGTTCTGGGCCGACCAGGTGATCGCGCTCGACGCGCTCAATCCGCAGGTT
GCCGCACGTCTCGCAAGAGCCCTGGAACTGTGGCGGCGCTTCACGCCCCGGCTGCGCGACCAGATGCGCGCGGCACTTGA
AAAGGTCGCGGCTCAGGCGAAATCGCGCGACGTGCGCGAAATCGTCGAGAAGGCGCTGGCCTGA

Upstream 100 bases:

>100_bases
TATCGTCGCCCGGCGTCTGCCGCGCGGGCGGCCCGATGATACGCTGACTGCGAACGGCGGCAAAAAGTTCTGTCCGCACG
ATCGGCCGAGGCTTTGTACA

Downstream 100 bases:

>100_bases
TCCTGCGTTTTTCCAGCGAAGTCGGAAGCCGGCACATGTGCCGGCTTTTTTTATTTGCGACCTGCCATTGCGCTTACGCC
TTTCGTCCGACTCGTTTGTC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 927; Mature: 926

Protein sequence:

>927_residues
MTRSPGALSVVALYTTRRLRAYSRTHIMADTETPQVIRRADYAPPAFLIDTVALEFDLVPERTVVRNTMRIRRNPDAVRA
THLDLMGEDLTFVEALLDGKPYADVHPHEHGLTVDNVPDSFELTLTGICNPAANTTLSGLYVSSGNFFTQCEAEGFRRIT
WFLDRPDVMATYTVTLRADKAAYPVLLSNGNLLEQGELPDGRHFARWEDPFRKPSYLFALVAGKLVALEERVKSGSGKDK
LLQVWVEPHDLDKTRHAMDSLIHSIRWDEARFGLELDLDRFMIVAVSDFNMGAMENKGLNIFNTKYVLANPETATDTDFS
NIEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMASGGSAGEDQAARATKRIEDVRVLRQMQFAEDAGP
MAHPVRPESYVEINNFYTMTVYEKGSEVVRMYQTLFGREGFRRGMDLYFKRHDGQAVTCDDFRHAMADANGRDLTQYERW
YSQAGTPRISVDTHYDAAQKRYTVKLKQGYGDASQAARDTQKGPLLIPVAIGLIGDDGNDMPLRLEGEAAASPHSTRVLE
FTQAEQSFTFVDVAEKPLPSLLRNFSAPVVVEYDYTADELAFLLAHDSDPFNRWEAGQRLATRELLTLAEHAATGKALEL
DDTVVAAFGRVLNDETLSPAFRELTLMLPSEAYLAEQMEESNPAAVHSARQFVRKRMASALKGDWLAIYERHQTPGAYEP
TPTAAGHRALKNLALAYIAELDDPTDARRLAKAQYDAANNMTDRASALSALLTAGVSNGGAAAAEALDDFYRRFEDEPLV
IDKWFALQAMQRGTKQRPVIEIVRTLMTHPAFNLKNPNRARSLIFSFCSANPAQFHAEDGSGYAFWADQVIALDALNPQV
AARLARALELWRRFTPRLRDQMRAALEKVAAQAKSRDVREIVEKALA

Sequences:

>Translated_927_residues
MTRSPGALSVVALYTTRRLRAYSRTHIMADTETPQVIRRADYAPPAFLIDTVALEFDLVPERTVVRNTMRIRRNPDAVRA
THLDLMGEDLTFVEALLDGKPYADVHPHEHGLTVDNVPDSFELTLTGICNPAANTTLSGLYVSSGNFFTQCEAEGFRRIT
WFLDRPDVMATYTVTLRADKAAYPVLLSNGNLLEQGELPDGRHFARWEDPFRKPSYLFALVAGKLVALEERVKSGSGKDK
LLQVWVEPHDLDKTRHAMDSLIHSIRWDEARFGLELDLDRFMIVAVSDFNMGAMENKGLNIFNTKYVLANPETATDTDFS
NIEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMASGGSAGEDQAARATKRIEDVRVLRQMQFAEDAGP
MAHPVRPESYVEINNFYTMTVYEKGSEVVRMYQTLFGREGFRRGMDLYFKRHDGQAVTCDDFRHAMADANGRDLTQYERW
YSQAGTPRISVDTHYDAAQKRYTVKLKQGYGDASQAARDTQKGPLLIPVAIGLIGDDGNDMPLRLEGEAAASPHSTRVLE
FTQAEQSFTFVDVAEKPLPSLLRNFSAPVVVEYDYTADELAFLLAHDSDPFNRWEAGQRLATRELLTLAEHAATGKALEL
DDTVVAAFGRVLNDETLSPAFRELTLMLPSEAYLAEQMEESNPAAVHSARQFVRKRMASALKGDWLAIYERHQTPGAYEP
TPTAAGHRALKNLALAYIAELDDPTDARRLAKAQYDAANNMTDRASALSALLTAGVSNGGAAAAEALDDFYRRFEDEPLV
IDKWFALQAMQRGTKQRPVIEIVRTLMTHPAFNLKNPNRARSLIFSFCSANPAQFHAEDGSGYAFWADQVIALDALNPQV
AARLARALELWRRFTPRLRDQMRAALEKVAAQAKSRDVREIVEKALA
>Mature_926_residues
TRSPGALSVVALYTTRRLRAYSRTHIMADTETPQVIRRADYAPPAFLIDTVALEFDLVPERTVVRNTMRIRRNPDAVRAT
HLDLMGEDLTFVEALLDGKPYADVHPHEHGLTVDNVPDSFELTLTGICNPAANTTLSGLYVSSGNFFTQCEAEGFRRITW
FLDRPDVMATYTVTLRADKAAYPVLLSNGNLLEQGELPDGRHFARWEDPFRKPSYLFALVAGKLVALEERVKSGSGKDKL
LQVWVEPHDLDKTRHAMDSLIHSIRWDEARFGLELDLDRFMIVAVSDFNMGAMENKGLNIFNTKYVLANPETATDTDFSN
IEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSADMASGGSAGEDQAARATKRIEDVRVLRQMQFAEDAGPM
AHPVRPESYVEINNFYTMTVYEKGSEVVRMYQTLFGREGFRRGMDLYFKRHDGQAVTCDDFRHAMADANGRDLTQYERWY
SQAGTPRISVDTHYDAAQKRYTVKLKQGYGDASQAARDTQKGPLLIPVAIGLIGDDGNDMPLRLEGEAAASPHSTRVLEF
TQAEQSFTFVDVAEKPLPSLLRNFSAPVVVEYDYTADELAFLLAHDSDPFNRWEAGQRLATRELLTLAEHAATGKALELD
DTVVAAFGRVLNDETLSPAFRELTLMLPSEAYLAEQMEESNPAAVHSARQFVRKRMASALKGDWLAIYERHQTPGAYEPT
PTAAGHRALKNLALAYIAELDDPTDARRLAKAQYDAANNMTDRASALSALLTAGVSNGGAAAAEALDDFYRRFEDEPLVI
DKWFALQAMQRGTKQRPVIEIVRTLMTHPAFNLKNPNRARSLIFSFCSANPAQFHAEDGSGYAFWADQVIALDALNPQVA
ARLARALELWRRFTPRLRDQMRAALEKVAAQAKSRDVREIVEKALA

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=402, Percent_Identity=24.8756218905473, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI132814467, Length=346, Percent_Identity=25.1445086705202, Blast_Score=110, Evalue=8e-24,
Organism=Homo sapiens, GI61742777, Length=334, Percent_Identity=23.6526946107784, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI61742775, Length=334, Percent_Identity=23.6526946107784, Blast_Score=105, Evalue=2e-22,
Organism=Homo sapiens, GI310123622, Length=307, Percent_Identity=26.7100977198697, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI310133497, Length=307, Percent_Identity=26.7100977198697, Blast_Score=97, Evalue=7e-20,
Organism=Homo sapiens, GI157266300, Length=367, Percent_Identity=24.2506811989101, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI194306629, Length=307, Percent_Identity=22.8013029315961, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI11641261, Length=307, Percent_Identity=22.8013029315961, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI94818901, Length=327, Percent_Identity=22.6299694189602, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI94818891, Length=327, Percent_Identity=22.6299694189602, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI4505029, Length=393, Percent_Identity=26.4631043256997, Blast_Score=83, Evalue=1e-15,
Organism=Homo sapiens, GI7019561, Length=344, Percent_Identity=25.2906976744186, Blast_Score=80, Evalue=8e-15,
Organism=Escherichia coli, GI1787163, Length=899, Percent_Identity=46.8298109010011, Blast_Score=757, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=401, Percent_Identity=26.1845386533666, Blast_Score=127, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71989076, Length=401, Percent_Identity=26.1845386533666, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI115533278, Length=467, Percent_Identity=24.4111349036403, Blast_Score=107, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569221, Length=380, Percent_Identity=25.5263157894737, Blast_Score=107, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI115533276, Length=467, Percent_Identity=24.4111349036403, Blast_Score=107, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17569225, Length=355, Percent_Identity=27.887323943662, Blast_Score=105, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193206928, Length=399, Percent_Identity=26.3157894736842, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI193206926, Length=399, Percent_Identity=26.5664160401003, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI133903840, Length=426, Percent_Identity=20.8920187793427, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71990873, Length=358, Percent_Identity=24.8603351955307, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71984339, Length=362, Percent_Identity=23.7569060773481, Blast_Score=77, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI71984353, Length=362, Percent_Identity=23.7569060773481, Blast_Score=77, Evalue=6e-14,
Organism=Saccharomyces cerevisiae, GI6321837, Length=428, Percent_Identity=25.4672897196262, Blast_Score=115, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI9755335, Length=345, Percent_Identity=26.0869565217391, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24655257, Length=401, Percent_Identity=27.1820448877805, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24655252, Length=401, Percent_Identity=27.1820448877805, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655274, Length=401, Percent_Identity=27.1820448877805, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655260, Length=401, Percent_Identity=27.1820448877805, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655265, Length=401, Percent_Identity=27.1820448877805, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24655268, Length=401, Percent_Identity=27.1820448877805, Blast_Score=135, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24646514, Length=352, Percent_Identity=27.5568181818182, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646516, Length=350, Percent_Identity=28.2857142857143, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24646518, Length=353, Percent_Identity=28.6118980169972, Blast_Score=114, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24651025, Length=302, Percent_Identity=29.4701986754967, Blast_Score=109, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24651023, Length=302, Percent_Identity=29.4701986754967, Blast_Score=109, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24651021, Length=302, Percent_Identity=29.4701986754967, Blast_Score=109, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24646512, Length=386, Percent_Identity=25.1295336787565, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646510, Length=386, Percent_Identity=25.1295336787565, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24651016, Length=290, Percent_Identity=27.5862068965517, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI21358341, Length=462, Percent_Identity=24.4588744588745, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24648786, Length=399, Percent_Identity=26.5664160401003, Blast_Score=96, Evalue=2e-19,
Organism=Drosophila melanogaster, GI221379089, Length=358, Percent_Identity=27.0949720670391, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI45550850, Length=474, Percent_Identity=24.2616033755274, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24650973, Length=474, Percent_Identity=24.2616033755274, Blast_Score=92, Evalue=2e-18,
Organism=Drosophila melanogaster, GI161078673, Length=389, Percent_Identity=24.4215938303342, Blast_Score=90, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28571901, Length=389, Percent_Identity=24.4215938303342, Blast_Score=90, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24648790, Length=388, Percent_Identity=24.2268041237113, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28571792, Length=384, Percent_Identity=25.78125, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24585062, Length=386, Percent_Identity=24.3523316062176, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585064, Length=386, Percent_Identity=24.3523316062176, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585066, Length=386, Percent_Identity=24.3523316062176, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI45550350, Length=381, Percent_Identity=24.4094488188976, Blast_Score=74, Evalue=6e-13,
Organism=Drosophila melanogaster, GI221330574, Length=358, Percent_Identity=23.1843575418994, Blast_Score=69, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 103848; Mature: 103717

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRSPGALSVVALYTTRRLRAYSRTHIMADTETPQVIRRADYAPPAFLIDTVALEFDLVP
CCCCCCCEEEEHHHHHHHHHHHHHHEEEECCCCHHHHHHCCCCCCHHHHHHHHHEEECCC
ERTVVRNTMRIRRNPDAVRATHLDLMGEDLTFVEALLDGKPYADVHPHEHGLTVDNVPDS
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
FELTLTGICNPAANTTLSGLYVSSGNFFTQCEAEGFRRITWFLDRPDVMATYTVTLRADK
EEEEEEECCCCCCCCEEEEEEEECCCEEEEECCCCCEEEEEEECCCCEEEEEEEEEEECC
AAYPVLLSNGNLLEQGELPDGRHFARWEDPFRKPSYLFALVAGKLVALEERVKSGSGKDK
CCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
LLQVWVEPHDLDKTRHAMDSLIHSIRWDEARFGLELDLDRFMIVAVSDFNMGAMENKGLN
EEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCEEECCCEEEEEEEECCCCCCCCCCCCE
IFNTKYVLANPETATDTDFSNIEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQE
EEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCC
FSADMASGGSAGEDQAARATKRIEDVRVLRQMQFAEDAGPMAHPVRPESYVEINNFYTMT
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEE
VYEKGSEVVRMYQTLFGREGFRRGMDLYFKRHDGQAVTCDDFRHAMADANGRDLTQYERW
EECCCHHHHHHHHHHHCHHHHHCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCHHHHHHH
YSQAGTPRISVDTHYDAAQKRYTVKLKQGYGDASQAARDTQKGPLLIPVAIGLIGDDGND
HHHCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCC
MPLRLEGEAAASPHSTRVLEFTQAEQSFTFVDVAEKPLPSLLRNFSAPVVVEYDYTADEL
CCEEECCCCCCCCCCCEEEEEEHHCCCEEEEEHHHCHHHHHHHHCCCCEEEEECCCHHHH
AFLLAHDSDPFNRWEAGQRLATRELLTLAEHAATGKALELDDTVVAAFGRVLNDETLSPA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCHH
FRELTLMLPSEAYLAEQMEESNPAAVHSARQFVRKRMASALKGDWLAIYERHQTPGAYEP
HHHHEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
TPTAAGHRALKNLALAYIAELDDPTDARRLAKAQYDAANNMTDRASALSALLTAGVSNGG
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
AAAAEALDDFYRRFEDEPLVIDKWFALQAMQRGTKQRPVIEIVRTLMTHPAFNLKNPNRA
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHH
RSLIFSFCSANPAQFHAEDGSGYAFWADQVIALDALNPQVAARLARALELWRRFTPRLRD
HHHHHHHHCCCCCEEECCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCHHHHH
QMRAALEKVAAQAKSRDVREIVEKALA
HHHHHHHHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
TRSPGALSVVALYTTRRLRAYSRTHIMADTETPQVIRRADYAPPAFLIDTVALEFDLVP
CCCCCCEEEEHHHHHHHHHHHHHHEEEECCCCHHHHHHCCCCCCHHHHHHHHHEEECCC
ERTVVRNTMRIRRNPDAVRATHLDLMGEDLTFVEALLDGKPYADVHPHEHGLTVDNVPDS
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCEECCCCCC
FELTLTGICNPAANTTLSGLYVSSGNFFTQCEAEGFRRITWFLDRPDVMATYTVTLRADK
EEEEEEECCCCCCCCEEEEEEEECCCEEEEECCCCCEEEEEEECCCCEEEEEEEEEEECC
AAYPVLLSNGNLLEQGELPDGRHFARWEDPFRKPSYLFALVAGKLVALEERVKSGSGKDK
CCCCEEECCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCE
LLQVWVEPHDLDKTRHAMDSLIHSIRWDEARFGLELDLDRFMIVAVSDFNMGAMENKGLN
EEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCEEECCCEEEEEEEECCCCCCCCCCCCE
IFNTKYVLANPETATDTDFSNIEAVVGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQE
EEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHCCCEEEECCC
FSADMASGGSAGEDQAARATKRIEDVRVLRQMQFAEDAGPMAHPVRPESYVEINNFYTMT
CCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEE
VYEKGSEVVRMYQTLFGREGFRRGMDLYFKRHDGQAVTCDDFRHAMADANGRDLTQYERW
EECCCHHHHHHHHHHHCHHHHHCCCCEEEEECCCCEEEHHHHHHHHHCCCCCCHHHHHHH
YSQAGTPRISVDTHYDAAQKRYTVKLKQGYGDASQAARDTQKGPLLIPVAIGLIGDDGND
HHHCCCCEEEECCCCCCCCCEEEEEEECCCCCHHHHHHHCCCCCEEEEEEEEEECCCCCC
MPLRLEGEAAASPHSTRVLEFTQAEQSFTFVDVAEKPLPSLLRNFSAPVVVEYDYTADEL
CCEEECCCCCCCCCCCEEEEEEHHCCCEEEEEHHHCHHHHHHHHCCCCEEEEECCCHHHH
AFLLAHDSDPFNRWEAGQRLATRELLTLAEHAATGKALELDDTVVAAFGRVLNDETLSPA
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHCCCCCCHH
FRELTLMLPSEAYLAEQMEESNPAAVHSARQFVRKRMASALKGDWLAIYERHQTPGAYEP
HHHHEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCC
TPTAAGHRALKNLALAYIAELDDPTDARRLAKAQYDAANNMTDRASALSALLTAGVSNGG
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
AAAAEALDDFYRRFEDEPLVIDKWFALQAMQRGTKQRPVIEIVRTLMTHPAFNLKNPNRA
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCHHH
RSLIFSFCSANPAQFHAEDGSGYAFWADQVIALDALNPQVAARLARALELWRRFTPRLRD
HHHHHHHHCCCCCEEECCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHCHHHHH
QMRAALEKVAAQAKSRDVREIVEKALA
HHHHHHHHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]