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The map label for this gene is livK [C]

Identifier: 186475355

GI number: 186475355

Start: 666197

End: 667396

Strand: Direct

Name: livK [C]

Synonym: Bphy_0588

Alternate gene names: 186475355

Gene position: 666197-667396 (Clockwise)

Preceding gene: 186475354

Following gene: 186475356

Centisome position: 19.15

GC content: 60.58

Gene sequence:

>1200_bases
ATGCGAGTCAAGTTTGCTTGTGCCGTGTCTATCGCGGCCGCGGTTGCGCTGACCGCGTGCGGCAAAAAGAACGATGGCGA
AGCGGACAAGAGCGCGTCGGCTGCGGTCGCAGCGTCGGCGGCGCCCGCAAGCGAAGTGACGATCGTGAAGATCGGTCATG
CGGCCCCATTAACGGGCGGCATCGCACATCTGGGTAAGGACAATGAAAACGGGGCGCGTCTCGCTATTGAAGAGATCAAC
GCGCAGGGATTAACCATCGACGGTCGCAAGATCCAGTTGGAACTCGACGCACAGGACGACGCGGGCGATCCGAAAACGGG
CACGCAGGTCGCGCAGAAACTGGTGGACGATCATGTAGTGGCTGTAGTCGGGCACCTGAATTCGGGCGTATCGATTCCAG
CTTCGAAGATATATAGCGACGCGGGCATTGTGCAGATCTCCCCGTCCTCGACGAATCCGGCGTACACGCGACAAGGCTTC
AAGACGACCTACCGGGTCGTCGCGACCGATGCGCAGCAGGGTCCGGCATTGGCGAATTACGCGACGAAAGCACTCGGCGC
GAAACGGATCGCGGTCGTCGACGACGCGACTGCCTATGGCAAGGGTCTCGCTGACGAGTTCGCGAAGACGGCGGAAGCGG
GCGGCGCCAAGATCGTGGCGCGCGAGGCGACCAATGACCGGGCCACGGATTTCCGGGCCATCCTCACAAAGATTAAAAGT
GCCCAGCCGGACGCCATCATGTTCGGCGGCATGGATGCAACGGGCGGGCCGTTTGCGAAACAGGCAGCGGCGCTCGGAAT
CAGGGCAAAAATCCTTGGCGGCGACGGCGTGTGCACCGACAAGGTAGGGGAACTGGCGGGCAGTGCCGTCCAGAACCTCG
TGTGTTCGGAAGCGGGCCTTGCGCTTTCGAAGATGGAAAGGGGAGCGGACTTCGAGAAGAAGTACGACGCACGCTTCCAC
ACGCCGGTGCAGATTTACGCGCCGTTCACGTATGACGCTGTGTACGTGATCGTCGATGCAATGAAGCGCGCCAATTCTAT
CGAGCCGCCCAAGGTGCTCGCTGCGATGCCTTCGACCGATTACACAGGTGTGATCGGCCACATCGCATTCGACGACAAGG
GCGACCTGAAAGAAGGCGCCATTACGCTTTACGACTTCAAGGACGGCAAGAAAGCGGTCCTCGACGTCGTGAAGATGTAA

Upstream 100 bases:

>100_bases
ACAATATTGCCCGTCGCAGAATTGGAGTTACAATGCGCGCGTTCTCAGGGCTAGAGCGCCTTGAAACGCCAGATTTTGCA
AGGCGCAGGAGACCTATTTA

Downstream 100 bases:

>100_bases
TGGCGGGACGTACAGCCTGACGGCACCGGACCATCCGACGGTGCCGTTTTTGCATCCGCGTCGAGCGCGCGGGCCGCTGC
AACCCAGCGGCCACGAGCGC

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MRVKFACAVSIAAAVALTACGKKNDGEADKSASAAVAASAAPASEVTIVKIGHAAPLTGGIAHLGKDNENGARLAIEEIN
AQGLTIDGRKIQLELDAQDDAGDPKTGTQVAQKLVDDHVVAVVGHLNSGVSIPASKIYSDAGIVQISPSSTNPAYTRQGF
KTTYRVVATDAQQGPALANYATKALGAKRIAVVDDATAYGKGLADEFAKTAEAGGAKIVAREATNDRATDFRAILTKIKS
AQPDAIMFGGMDATGGPFAKQAAALGIRAKILGGDGVCTDKVGELAGSAVQNLVCSEAGLALSKMERGADFEKKYDARFH
TPVQIYAPFTYDAVYVIVDAMKRANSIEPPKVLAAMPSTDYTGVIGHIAFDDKGDLKEGAITLYDFKDGKKAVLDVVKM

Sequences:

>Translated_399_residues
MRVKFACAVSIAAAVALTACGKKNDGEADKSASAAVAASAAPASEVTIVKIGHAAPLTGGIAHLGKDNENGARLAIEEIN
AQGLTIDGRKIQLELDAQDDAGDPKTGTQVAQKLVDDHVVAVVGHLNSGVSIPASKIYSDAGIVQISPSSTNPAYTRQGF
KTTYRVVATDAQQGPALANYATKALGAKRIAVVDDATAYGKGLADEFAKTAEAGGAKIVAREATNDRATDFRAILTKIKS
AQPDAIMFGGMDATGGPFAKQAAALGIRAKILGGDGVCTDKVGELAGSAVQNLVCSEAGLALSKMERGADFEKKYDARFH
TPVQIYAPFTYDAVYVIVDAMKRANSIEPPKVLAAMPSTDYTGVIGHIAFDDKGDLKEGAITLYDFKDGKKAVLDVVKM
>Mature_399_residues
MRVKFACAVSIAAAVALTACGKKNDGEADKSASAAVAASAAPASEVTIVKIGHAAPLTGGIAHLGKDNENGARLAIEEIN
AQGLTIDGRKIQLELDAQDDAGDPKTGTQVAQKLVDDHVVAVVGHLNSGVSIPASKIYSDAGIVQISPSSTNPAYTRQGF
KTTYRVVATDAQQGPALANYATKALGAKRIAVVDDATAYGKGLADEFAKTAEAGGAKIVAREATNDRATDFRAILTKIKS
AQPDAIMFGGMDATGGPFAKQAAALGIRAKILGGDGVCTDKVGELAGSAVQNLVCSEAGLALSKMERGADFEKKYDARFH
TPVQIYAPFTYDAVYVIVDAMKRANSIEPPKVLAAMPSTDYTGVIGHIAFDDKGDLKEGAITLYDFKDGKKAVLDVVKM

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=342, Percent_Identity=31.5789473684211, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI48994941, Length=338, Percent_Identity=28.698224852071, Blast_Score=155, Evalue=5e-39,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 41316; Mature: 41316

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKFACAVSIAAAVALTACGKKNDGEADKSASAAVAASAAPASEVTIVKIGHAAPLTGG
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEECCCCCCCEEEEEECCCCCCCCC
IAHLGKDNENGARLAIEEINAQGLTIDGRKIQLELDAQDDAGDPKTGTQVAQKLVDDHVV
HHHCCCCCCCCCEEEEEECCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHE
AVVGHLNSGVSIPASKIYSDAGIVQISPSSTNPAYTRQGFKTTYRVVATDAQQGPALANY
EEEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCHHHCCCCEEEEEEEECCCCCCHHHHH
ATKALGAKRIAVVDDATAYGKGLADEFAKTAEAGGAKIVAREATNDRATDFRAILTKIKS
HHHHCCCCEEEEEECCHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHC
AQPDAIMFGGMDATGGPFAKQAAALGIRAKILGGDGVCTDKVGELAGSAVQNLVCSEAGL
CCCCEEEEECCCCCCCCHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCH
ALSKMERGADFEKKYDARFHTPVQIYAPFTYDAVYVIVDAMKRANSIEPPKVLAAMPSTD
HHHHHHCCCCCHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
YTGVIGHIAFDDKGDLKEGAITLYDFKDGKKAVLDVVKM
CCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MRVKFACAVSIAAAVALTACGKKNDGEADKSASAAVAASAAPASEVTIVKIGHAAPLTGG
CCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHEECCCCCCCEEEEEECCCCCCCCC
IAHLGKDNENGARLAIEEINAQGLTIDGRKIQLELDAQDDAGDPKTGTQVAQKLVDDHVV
HHHCCCCCCCCCEEEEEECCCCCEEECCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHE
AVVGHLNSGVSIPASKIYSDAGIVQISPSSTNPAYTRQGFKTTYRVVATDAQQGPALANY
EEEECCCCCCCCCHHHHHCCCCEEEECCCCCCCCHHHCCCCEEEEEEEECCCCCCHHHHH
ATKALGAKRIAVVDDATAYGKGLADEFAKTAEAGGAKIVAREATNDRATDFRAILTKIKS
HHHHCCCCEEEEEECCHHHCCCHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHC
AQPDAIMFGGMDATGGPFAKQAAALGIRAKILGGDGVCTDKVGELAGSAVQNLVCSEAGL
CCCCEEEEECCCCCCCCHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCH
ALSKMERGADFEKKYDARFHTPVQIYAPFTYDAVYVIVDAMKRANSIEPPKVLAAMPSTD
HHHHHHCCCCCHHHCCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCC
YTGVIGHIAFDDKGDLKEGAITLYDFKDGKKAVLDVVKM
CCEEEEEEEECCCCCCCCCCEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA