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The map label for this gene is sucD [H]

Identifier: 186475212

GI number: 186475212

Start: 504234

End: 505115

Strand: Direct

Name: sucD [H]

Synonym: Bphy_0444

Alternate gene names: 186475212

Gene position: 504234-505115 (Clockwise)

Preceding gene: 186475211

Following gene: 186475213

Centisome position: 14.49

GC content: 62.47

Gene sequence:

>882_bases
ATGTCGATTCTGATCAACAAAGACACCAAGGTCATCACGCAGGGCATCACCGGCAAGACCGGTCAGTTCCACACGCGCGC
ATGCCGTGAATACGCAAACGGCCGCGAAGCATTCGTCGCAGGCGTGAACCCCAAGAAAGCCGGCGAAGACTTCGAAGGCA
TTCCTATCTACGCGAGCGTCAAGGAAGCGAAGGCGGAAACGGGCGCAACCGTTTCGGTCATCTACGTGCCGCCCGCAGGC
GCCGCTGCTGCGATCTGGGAAGCCGTCGAAGCCGACCTCGATCTCGCGATCTGCATCACGGAAGGCATCCCCGTGCGCGA
CATGATCGAAGTGAAGGACCGTATGCGCCGCGAGGGCCGCAAGACGCTGCTGCTTGGACCGAACTGCCCGGGCACGATCA
CGCCGGACGAACTGAAGATCGGCATCATGCCGGGCCACATCCACCGCAAGGGCCGCATCGGCGTCGTGTCGCGTTCGGGC
ACGCTGACGTATGAAGCAGTCGGCCAGCTGACGGCACTGGGCCTCGGCCAGTCGTCGGCAGTCGGTATCGGCGGCGATCC
GATCAACGGTCTGAAACACATCGACGTGATGAAGATGTTCAACGACGATCCGGATACGGACGCCGTCATCATGATCGGCG
AAATCGGCGGTCCGGACGAAGCGAACGCTGCGTACTGGATCAAGGACAACATGAAGAAGCCGGTGGTCGGCTTCATCGCG
GGCGTCACGGCGCCTCCGGGCAAGCGCATGGGCCACGCCGGCGCGCTGATCTCGGGCGGTGCGGATACGGCCGACGCGAA
GCTGGAAATCATGGACGCGTGCGGCATCAAAGTCACGAAGAACCCGTCCGAAATGGCCCGACTGCTGAAGTCGGTGCTGT
AA

Upstream 100 bases:

>100_bases
ATCACCGGATTACGAATGGCGGCGCGCGAGCGTCGCGGGCAAAGGCTATTTGCCGCGCGAGACGCGTTGAGCGCGCCACC
AAACGAACAGAGGTCAATAC

Downstream 100 bases:

>100_bases
GAAGGGTTGCGATAAGCTCAAGAAACGCCGGTCGACGCCGGCGTTTTTTGATACTCTTGCGAAGGCCTTTCGTAAGACGC
AGCGACAAGCGAGGGAGCGA

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVIMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTADAKLEIMDACGIKVTKNPSEMARLLKSVL

Sequences:

>Translated_293_residues
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVIMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTADAKLEIMDACGIKVTKNPSEMARLLKSVL
>Mature_292_residues
SILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAGA
AAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGT
LTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVIMIGEIGGPDEANAAYWIKDNMKKPVVGFIAG
VTAPPGKRMGHAGALISGGADTADAKLEIMDACGIKVTKNPSEMARLLKSVL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=55.4006968641115, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI38569423, Length=209, Percent_Identity=29.6650717703349, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI38569421, Length=209, Percent_Identity=29.6650717703349, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=54.6075085324232, Blast_Score=315, Evalue=2e-87,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=28.1081081081081, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=54.5138888888889, Blast_Score=296, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI17553126, Length=296, Percent_Identity=53.0405405405405, Blast_Score=290, Evalue=4e-79,
Organism=Caenorhabditis elegans, GI17557344, Length=321, Percent_Identity=26.1682242990654, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=47.6351351351351, Blast_Score=259, Evalue=3e-70,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=48.6301369863014, Blast_Score=279, Evalue=1e-75,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=53.0821917808219, Blast_Score=270, Evalue=1e-72,
Organism=Drosophila melanogaster, GI281363477, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI281363475, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281363473, Length=256, Percent_Identity=26.171875, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30830; Mature: 30699

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASV
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCEEEEEH
KEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGR
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
EEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCCCEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPDTDAVIMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHEE
GVTAPPGKRMGHAGALISGGADTADAKLEIMDACGIKVTKNPSEMARLLKSVL
CCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHC
>Mature Secondary Structure 
SILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKKAGEDFEGIPIYASV
EEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCHHCCCCCCCCEEEEEH
KEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGR
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
EEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCCCEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPDTDAVIMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCHHHHEE
GVTAPPGKRMGHAGALISGGADTADAKLEIMDACGIKVTKNPSEMARLLKSVL
CCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]