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The map label for this gene is grx [H]

Identifier: 186475037

GI number: 186475037

Start: 311854

End: 312102

Strand: Direct

Name: grx [H]

Synonym: Bphy_0268

Alternate gene names: 186475037

Gene position: 311854-312102 (Clockwise)

Preceding gene: 186475036

Following gene: 186475038

Centisome position: 8.96

GC content: 64.66

Gene sequence:

>249_bases
ATGTACAGCACGCAGGTGTGCCCATATTGCCAGATGGCTGAACGTCTACTAAAGTCGCGCGGCGTCGAGCACATCGAAAA
GGTGCTGATCGACAAGGATCCGGCGCGCCGCCAGGAAATGATGACGCGCACGGGCCGTCGCACGGTGCCGCAGGTGTACA
TCGGCGAGACGCACGTCGGCGGCTACGACGATCTGTCCGCGCTCGACCGCGCGGGCGGTCTGACGCCGTTGCTCGAAGCC
GTCGCCTGA

Upstream 100 bases:

>100_bases
GCTATGCGGAAGTGCACGTGCTGGAAGGCGGTGTCAACGCCTGGCAGCAGGCGGGCATGCCCGTCGTCAAACAAGGAGTT
GCGAAGTGAACAGAGTGATC

Downstream 100 bases:

>100_bases
CGTCGGAGCGAAACACCGCTTGCGCGCCGCGTCGATCGGTCGTCGCAGCGCGCGGCAGCCAATAAGATGAAGGCCGGGCA
ACGCTTTGAATCGTTCGCAC

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 82; Mature: 82

Protein sequence:

>82_residues
MYSTQVCPYCQMAERLLKSRGVEHIEKVLIDKDPARRQEMMTRTGRRTVPQVYIGETHVGGYDDLSALDRAGGLTPLLEA
VA

Sequences:

>Translated_82_residues
MYSTQVCPYCQMAERLLKSRGVEHIEKVLIDKDPARRQEMMTRTGRRTVPQVYIGETHVGGYDDLSALDRAGGLTPLLEA
VA
>Mature_82_residues
MYSTQVCPYCQMAERLLKSRGVEHIEKVLIDKDPARRQEMMTRTGRRTVPQVYIGETHVGGYDDLSALDRAGGLTPLLEA
VA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=79, Percent_Identity=50.6329113924051, Blast_Score=88, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9194; Mature: 9194

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSTQVCPYCQMAERLLKSRGVEHIEKVLIDKDPARRQEMMTRTGRRTVPQVYIGETHVG
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCC
GYDDLSALDRAGGLTPLLEAVA
CCHHHHHHHHCCCHHHHHHHHC
>Mature Secondary Structure
MYSTQVCPYCQMAERLLKSRGVEHIEKVLIDKDPARRQEMMTRTGRRTVPQVYIGETHVG
CCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCEEECCCCCCC
GYDDLSALDRAGGLTPLLEAVA
CCHHHHHHHHCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]