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The map label for this gene is paaG [C]

Identifier: 186474967

GI number: 186474967

Start: 222377

End: 223237

Strand: Direct

Name: paaG [C]

Synonym: Bphy_0198

Alternate gene names: 186474967

Gene position: 222377-223237 (Clockwise)

Preceding gene: 186474966

Following gene: 186474968

Centisome position: 6.39

GC content: 65.85

Gene sequence:

>861_bases
ATGTCTGCCATGTCTCACGAATCGGAATCCCACACGGTCGAACCCGCGTTCTACGCGCACTACAGGTCGCTGCGCGTGCG
GCGTCACGCGCACGGCATCCTCGAAATCGTGATGAGCGGCGAGGGCGCCAACAAAAGCAATCTCGCTACCGCCGATGCGA
ACATGCATCGTGAGCTGGCCGACATCTGGCGCGATGTCGACCGCGATCCCGACACGCGGGTCGCGGTGATTCGCGGCGAA
GGCAAGGGCTTTTCGGCGGGGGGCGATCTCGGGCTCGTCGAAGACATGGCGAACGACTTCGACGTGCGCACGCGCGTGTG
GCGCGAGGCGCGCGATCTCGTCTACAACGTGATCAACTGCAGCAAGCCGATCGTCTCGGCGATGCACGGGCCGGCCGTCG
GCGCGGGGCTCGTCGCGGGACTGCTCGCGGATATCTCGATTGCGACGAAATCGGCGCGCATCATCGATGGTCATACGCGG
CTGGGCGTCGCGGCGGGCGACCATGCGGCGATCGTTTGGCCGCTCCTGTGCGGCATGGCGAAGGCGAAGTACTACCTGAT
GCTGTGCGAACCCGTGAGCGGCGAAGAAGCGGAGCGCATCGGTCTCGTGTCGCTAGCCGTCGACGACAACGATCTGCTGC
CGAAAACCTTCGAAGTCGCGCGCAAGCTCGCGAGCGGTTCGCAGACGGCGATCCGCTGGACCAAGTACGCGCTGAACAAT
TGGCTGCGCTCGGCGGGCCCCGCTTTCGACACGTCGCTCGCGCTCGAATTCATGGGTTTCGCGGGACCGGACGTGCGCGA
GGGCGTGGCGTCGCTGCGCGAGCGGCGCGCGCCGGATTTTCCGGGCAAAGAGCCGTTCTGA

Upstream 100 bases:

>100_bases
GGTATATCAGCCGCGCTGAACGCGGCGCTTTCGGGTGACGCAGCGTCGGCTGCGTCGCGCGCCTGATGTGTGGTCCGACG
CCGACGCGTCGCTTCTTCGG

Downstream 100 bases:

>100_bases
GGGAAGATGCCTTGCGTTGCGGATCGGCGGACGCAAAACCGTCACGGCACGCGGCGCACGATAGCCGCGCGATCGCTTCG
CAAACAGTTCGCACGAAAAG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MSAMSHESESHTVEPAFYAHYRSLRVRRHAHGILEIVMSGEGANKSNLATADANMHRELADIWRDVDRDPDTRVAVIRGE
GKGFSAGGDLGLVEDMANDFDVRTRVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIATKSARIIDGHTR
LGVAAGDHAAIVWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVDDNDLLPKTFEVARKLASGSQTAIRWTKYALNN
WLRSAGPAFDTSLALEFMGFAGPDVREGVASLRERRAPDFPGKEPF

Sequences:

>Translated_286_residues
MSAMSHESESHTVEPAFYAHYRSLRVRRHAHGILEIVMSGEGANKSNLATADANMHRELADIWRDVDRDPDTRVAVIRGE
GKGFSAGGDLGLVEDMANDFDVRTRVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIATKSARIIDGHTR
LGVAAGDHAAIVWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVDDNDLLPKTFEVARKLASGSQTAIRWTKYALNN
WLRSAGPAFDTSLALEFMGFAGPDVREGVASLRERRAPDFPGKEPF
>Mature_285_residues
SAMSHESESHTVEPAFYAHYRSLRVRRHAHGILEIVMSGEGANKSNLATADANMHRELADIWRDVDRDPDTRVAVIRGEG
KGFSAGGDLGLVEDMANDFDVRTRVWREARDLVYNVINCSKPIVSAMHGPAVGAGLVAGLLADISIATKSARIIDGHTRL
GVAAGDHAAIVWPLLCGMAKAKYYLMLCEPVSGEEAERIGLVSLAVDDNDLLPKTFEVARKLASGSQTAIRWTKYALNNW
LRSAGPAFDTSLALEFMGFAGPDVREGVASLRERRAPDFPGKEPF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI31542718, Length=254, Percent_Identity=26.3779527559055, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI194097323, Length=231, Percent_Identity=23.8095238095238, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI70995211, Length=232, Percent_Identity=29.3103448275862, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787660, Length=253, Percent_Identity=31.2252964426877, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787659, Length=222, Percent_Identity=30.1801801801802, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788597, Length=262, Percent_Identity=23.6641221374046, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI221142681, Length=215, Percent_Identity=28.8372093023256, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540714, Length=198, Percent_Identity=28.2828282828283, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17534483, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=226, Percent_Identity=26.5486725663717, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560910, Length=183, Percent_Identity=27.3224043715847, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=245, Percent_Identity=24.8979591836735, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17536985, Length=209, Percent_Identity=26.7942583732057, Blast_Score=64, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19922422, Length=257, Percent_Identity=25.6809338521401, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653139, Length=242, Percent_Identity=26.4462809917355, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24654903, Length=188, Percent_Identity=25.531914893617, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI20129971, Length=239, Percent_Identity=24.6861924686192, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653477, Length=239, Percent_Identity=24.6861924686192, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 31072; Mature: 30940

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAMSHESESHTVEPAFYAHYRSLRVRRHAHGILEIVMSGEGANKSNLATADANMHRELA
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEECCHHHHHHHH
DIWRDVDRDPDTRVAVIRGEGKGFSAGGDLGLVEDMANDFDVRTRVWREARDLVYNVINC
HHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
SKPIVSAMHGPAVGAGLVAGLLADISIATKSARIIDGHTRLGVAAGDHAAIVWPLLCGMA
CHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHH
KAKYYLMLCEPVSGEEAERIGLVSLAVDDNDLLPKTFEVARKLASGSQTAIRWTKYALNN
HCEEEEEEECCCCCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
WLRSAGPAFDTSLALEFMGFAGPDVREGVASLRERRAPDFPGKEPF
HHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
SAMSHESESHTVEPAFYAHYRSLRVRRHAHGILEIVMSGEGANKSNLATADANMHRELA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEECCHHHHHHHH
DIWRDVDRDPDTRVAVIRGEGKGFSAGGDLGLVEDMANDFDVRTRVWREARDLVYNVINC
HHHHHCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHC
SKPIVSAMHGPAVGAGLVAGLLADISIATKSARIIDGHTRLGVAAGDHAAIVWPLLCGMA
CHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHHHHHHH
KAKYYLMLCEPVSGEEAERIGLVSLAVDDNDLLPKTFEVARKLASGSQTAIRWTKYALNN
HCEEEEEEECCCCCCCHHHEEEEEEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
WLRSAGPAFDTSLALEFMGFAGPDVREGVASLRERRAPDFPGKEPF
HHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA