Click here to switch to the map view.

The map label for this gene is livK [C]

Identifier: 186474882

GI number: 186474882

Start: 121607

End: 122752

Strand: Direct

Name: livK [C]

Synonym: Bphy_0112

Alternate gene names: 186474882

Gene position: 121607-122752 (Clockwise)

Preceding gene: 186474879

Following gene: 186474883

Centisome position: 3.5

GC content: 60.21

Gene sequence:

>1146_bases
ATGAACATCAAAATCCAAAAGCTGTTGCCGATCAGCGCTGCGGCGATGCTGTTTGCAACGTTGGCGACGACGGCTTCGGC
CGACACAGTGGTCAAGATCGGCCACGTCGCGCCTTTGACGGGTGGCATCGCTCACCTGGGCAAGGACAACGAAAACGGCG
CTCGTCTCGCAGTCGAAGAGATCAACGCCAAGGGTCTGACGATCGGCGGCCAGAAGATCACGCTGCAACTGGATGCACAA
GACGACGCAGCCGACCCGCGTACTGCTACGCAGGTCGCACAGAAGCTGGTCGACGACAAGGTTGTCGCCGTCGTTGGCCA
CCTGAACTCGGGCACGTCGATTCCGGCTTCGAAGATCTACAGCGATGCAGGCATCGTTCAGATCTCGCCGTCGGCAACGA
ACCCGGCATACACGCAACAGGGCTTCAAGACGACGTACCGCGTCGTGGCAACCGATGCGCAGCAAGGCCCGGCACTGGCC
AACTACGCAGCGAAGGGCCTGAAGGTCAAGAGCGTCGCGATCGTCGACGACTCGACGGCATACGGCCAGGGTCTCGCGAA
CGAATTCGAAAAGACGGCAAAGTCGCTCGGTCTGAACGTGATGTCGCATGACGCGACGAACGACAAGGCTGTCGACTTCC
GCGCAATTCTGACGAAGATCAAGGGCGAAAACCCGGACGCGATCATGTACGGCGGCATGGACGCCACGGGCGGCCCGTTC
GCGAAGCAAGCCAAGCAGCTTGGCCTGCGCGCGAAGGTGCTGGCGGGCGACGGCGTGTGTACCGACAAGCTGTCTGACCT
GGCTGGCGACGCAACCGACAACATCGTCTGCTCGGAAGCCGGTATGGCGCTCGAGAAGATGGAAGGCGGCCAGGCGTTCC
AGGCGAAGTATCAGAAGCGTTTCGGTCAGCCGATCCAGATTTACGCTCCGTTCACGTATGACGCTGTGTACATCATCGTC
GACGCAATGAAGCGTGCTGGCTCGACGGATCCGGCGAAGATCCTGGCAGCGATGCCGAACACCGACTACAAGGGTGTGAT
CGGCGAAACGACCTTCGACTCGAAGGGCGACCTGAAGCACGGTGTGATCTCGCTGTACAACTACAAGTCCGGCAAGAAGA
CGCTGCTCGACGTCGTGAAGATGTAA

Upstream 100 bases:

>100_bases
ATGCATCCGGCGGAGTCGTCCACGGGATTTGAGCGACACGTGAAGGAAGCGGGGCACAAGGGCGATTACGTTGTTTTTGG
GACCGAAATCGGAGACTTAC

Downstream 100 bases:

>100_bases
GAGCGGTCGGCGCAACCGGCGCGCACGCGGTCTCGCCGCGTCACGCAGGACGCAAACCGGCCTGACAAGGCATCATAGGA
GGCACGCGGGTTCATTCCCG

Product: extracellular ligand-binding receptor

Products: ADP; phosphate; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 381

Protein sequence:

>381_residues
MNIKIQKLLPISAAAMLFATLATTASADTVVKIGHVAPLTGGIAHLGKDNENGARLAVEEINAKGLTIGGQKITLQLDAQ
DDAADPRTATQVAQKLVDDKVVAVVGHLNSGTSIPASKIYSDAGIVQISPSATNPAYTQQGFKTTYRVVATDAQQGPALA
NYAAKGLKVKSVAIVDDSTAYGQGLANEFEKTAKSLGLNVMSHDATNDKAVDFRAILTKIKGENPDAIMYGGMDATGGPF
AKQAKQLGLRAKVLAGDGVCTDKLSDLAGDATDNIVCSEAGMALEKMEGGQAFQAKYQKRFGQPIQIYAPFTYDAVYIIV
DAMKRAGSTDPAKILAAMPNTDYKGVIGETTFDSKGDLKHGVISLYNYKSGKKTLLDVVKM

Sequences:

>Translated_381_residues
MNIKIQKLLPISAAAMLFATLATTASADTVVKIGHVAPLTGGIAHLGKDNENGARLAVEEINAKGLTIGGQKITLQLDAQ
DDAADPRTATQVAQKLVDDKVVAVVGHLNSGTSIPASKIYSDAGIVQISPSATNPAYTQQGFKTTYRVVATDAQQGPALA
NYAAKGLKVKSVAIVDDSTAYGQGLANEFEKTAKSLGLNVMSHDATNDKAVDFRAILTKIKGENPDAIMYGGMDATGGPF
AKQAKQLGLRAKVLAGDGVCTDKLSDLAGDATDNIVCSEAGMALEKMEGGQAFQAKYQKRFGQPIQIYAPFTYDAVYIIV
DAMKRAGSTDPAKILAAMPNTDYKGVIGETTFDSKGDLKHGVISLYNYKSGKKTLLDVVKM
>Mature_381_residues
MNIKIQKLLPISAAAMLFATLATTASADTVVKIGHVAPLTGGIAHLGKDNENGARLAVEEINAKGLTIGGQKITLQLDAQ
DDAADPRTATQVAQKLVDDKVVAVVGHLNSGTSIPASKIYSDAGIVQISPSATNPAYTQQGFKTTYRVVATDAQQGPALA
NYAAKGLKVKSVAIVDDSTAYGQGLANEFEKTAKSLGLNVMSHDATNDKAVDFRAILTKIKGENPDAIMYGGMDATGGPF
AKQAKQLGLRAKVLAGDGVCTDKLSDLAGDATDNIVCSEAGMALEKMEGGQAFQAKYQKRFGQPIQIYAPFTYDAVYIIV
DAMKRAGSTDPAKILAAMPNTDYKGVIGETTFDSKGDLKHGVISLYNYKSGKKTLLDVVKM

Specific function: Component of an amino-acid transport system (Potential) [H]

COG id: COG0683

COG function: function code E; ABC-type branched-chain amino acid transport systems, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the leucine-binding protein family [H]

Homologues:

Organism=Escherichia coli, GI1789867, Length=357, Percent_Identity=33.8935574229692, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI48994941, Length=370, Percent_Identity=31.8918918918919, Blast_Score=177, Evalue=8e-46,

Paralogues:

None

Copy number: 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001828
- InterPro:   IPR000709 [H]

Pfam domain/function: PF01094 ANF_receptor [H]

EC number: NA

Molecular weight: Translated: 40007; Mature: 40007

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKIQKLLPISAAAMLFATLATTASADTVVKIGHVAPLTGGIAHLGKDNENGARLAVEE
CCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHCCCCCCCCCEEEEEE
INAKGLTIGGQKITLQLDAQDDAADPRTATQVAQKLVDDKVVAVVGHLNSGTSIPASKIY
CCCCCEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHH
SDAGIVQISPSATNPAYTQQGFKTTYRVVATDAQQGPALANYAAKGLKVKSVAIVDDSTA
CCCCEEEECCCCCCCCHHHHCCCEEEEEEEECCCCCCHHHHHHHCCEEEEEEEEEECCCH
YGQGLANEFEKTAKSLGLNVMSHDATNDKAVDFRAILTKIKGENPDAIMYGGMDATGGPF
HCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHH
AKQAKQLGLRAKVLAGDGVCTDKLSDLAGDATDNIVCSEAGMALEKMEGGQAFQAKYQKR
HHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHCCCHHHHHHHHHH
FGQPIQIYAPFTYDAVYIIVDAMKRAGSTDPAKILAAMPNTDYKGVIGETTFDSKGDLKH
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCC
GVISLYNYKSGKKTLLDVVKM
CEEEEEECCCCHHHHHHHHCC
>Mature Secondary Structure
MNIKIQKLLPISAAAMLFATLATTASADTVVKIGHVAPLTGGIAHLGKDNENGARLAVEE
CCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHCCCCCCCCCEEEEEE
INAKGLTIGGQKITLQLDAQDDAADPRTATQVAQKLVDDKVVAVVGHLNSGTSIPASKIY
CCCCCEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHH
SDAGIVQISPSATNPAYTQQGFKTTYRVVATDAQQGPALANYAAKGLKVKSVAIVDDSTA
CCCCEEEECCCCCCCCHHHHCCCEEEEEEEECCCCCCHHHHHHHCCEEEEEEEEEECCCH
YGQGLANEFEKTAKSLGLNVMSHDATNDKAVDFRAILTKIKGENPDAIMYGGMDATGGPF
HCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHH
AKQAKQLGLRAKVLAGDGVCTDKLSDLAGDATDNIVCSEAGMALEKMEGGQAFQAKYQKR
HHHHHHCCCEEEEEECCCCCHHHHHHHCCCCCCCEEECCCCCHHHHHCCCHHHHHHHHHH
FGQPIQIYAPFTYDAVYIIVDAMKRAGSTDPAKILAAMPNTDYKGVIGETTFDSKGDLKH
CCCCEEEEECCCCCHHHHHHHHHHHCCCCCHHHHEEECCCCCCCCCCCCCCCCCCCCCCC
GVISLYNYKSGKKTLLDVVKM
CEEEEEECCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA