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The map label for this gene is actR [H]

Identifier: 186474839

GI number: 186474839

Start: 77830

End: 78372

Strand: Direct

Name: actR [H]

Synonym: Bphy_0068

Alternate gene names: 186474839

Gene position: 77830-78372 (Clockwise)

Preceding gene: 186474838

Following gene: 186474849

Centisome position: 2.24

GC content: 62.98

Gene sequence:

>543_bases
ATGAGCGACAAGAATTTCCTGGTCATCGACGACGACGAAGTGTTCTCCGGCATCCTTGCGCGCGGCCTCACGCGTCGCGG
CTTTACGGTATCGGAGGCACATAACGCCGACGAAGCGATTCGCCTCGCGAACCAGCAGAAGTTCGGGCAGATCACCGTCG
ATCTGCATCTGGGCAACGACTCCGGTCTGAATCTCGTCGCACCGCTGCGCGACCTGCAACCGGACGCGCGGATGCTCGTC
CTGACCGGGTACGCGAGCATCGCCACGGCCGTCCAGGCGGTGAAGGACGGCGCGGACAATTATCTGGCGAAGCCCGCGAA
TGTCGAAACGATTCTGTCCGCGTTGCAAACCGAAGCGAGCGCATTGCAGGCCGAGGAAGCGATCGAGAATCCGACGCCCT
TGTCAGTGGCGCGGCTCGAATGGGAGCACATTCAGCGCGTGCTTGCGGAGAACGGCGGCAATATCTCGGCGACGGCGCGC
GCGCTGAACATGCATCGGCGCACGTTGCAGCGCAAGCTGGCTAAGCGGCCCGTGAAGCAGTAG

Upstream 100 bases:

>100_bases
AGCCGCGCGGCACGCGCGCGGTGTTGCGGTTGCCTCTGGCCCGCGAGCAAACGGACGCGGGCCGGCACGGCGCCGCGTCG
TCCAACACGGAGAAACAAGC

Downstream 100 bases:

>100_bases
CCCGGCCGTCGCACATGGCGCATGAAGAAGGGCGGCGCTCCTCGCGGAGCGCCGCCCTCTTGTTTGGCCGGCCCGGCTCG
CGTTACAGCACGTAGCGCGA

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSDKNFLVIDDDEVFSGILARGLTRRGFTVSEAHNADEAIRLANQQKFGQITVDLHLGNDSGLNLVAPLRDLQPDARMLV
LTGYASIATAVQAVKDGADNYLAKPANVETILSALQTEASALQAEEAIENPTPLSVARLEWEHIQRVLAENGGNISATAR
ALNMHRRTLQRKLAKRPVKQ

Sequences:

>Translated_180_residues
MSDKNFLVIDDDEVFSGILARGLTRRGFTVSEAHNADEAIRLANQQKFGQITVDLHLGNDSGLNLVAPLRDLQPDARMLV
LTGYASIATAVQAVKDGADNYLAKPANVETILSALQTEASALQAEEAIENPTPLSVARLEWEHIQRVLAENGGNISATAR
ALNMHRRTLQRKLAKRPVKQ
>Mature_179_residues
SDKNFLVIDDDEVFSGILARGLTRRGFTVSEAHNADEAIRLANQQKFGQITVDLHLGNDSGLNLVAPLRDLQPDARMLVL
TGYASIATAVQAVKDGADNYLAKPANVETILSALQTEASALQAEEAIENPTPLSVARLEWEHIQRVLAENGGNISATARA
LNMHRRTLQRKLAKRPVKQ

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=129, Percent_Identity=30.2325581395349, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788905, Length=148, Percent_Identity=31.7567567567568, Blast_Score=64, Evalue=5e-12,
Organism=Escherichia coli, GI1786784, Length=160, Percent_Identity=26.875, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789809, Length=112, Percent_Identity=29.4642857142857, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19635; Mature: 19503

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKNFLVIDDDEVFSGILARGLTRRGFTVSEAHNADEAIRLANQQKFGQITVDLHLGND
CCCCCEEEECCHHHHHHHHHHHHCCCCCEEHHHCCHHHHHHHHCCCCCCEEEEEEEECCC
SGLNLVAPLRDLQPDARMLVLTGYASIATAVQAVKDGADNYLAKPANVETILSALQTEAS
CCCEEECCHHHCCCCCEEEEEECHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
ALQAEEAIENPTPLSVARLEWEHIQRVLAENGGNISATARALNMHRRTLQRKLAKRPVKQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SDKNFLVIDDDEVFSGILARGLTRRGFTVSEAHNADEAIRLANQQKFGQITVDLHLGND
CCCCEEEECCHHHHHHHHHHHHCCCCCEEHHHCCHHHHHHHHCCCCCCEEEEEEEECCC
SGLNLVAPLRDLQPDARMLVLTGYASIATAVQAVKDGADNYLAKPANVETILSALQTEAS
CCCEEECCHHHCCCCCEEEEEECHHHHHHHHHHHHCCCHHHCCCCCCHHHHHHHHHHHHH
ALQAEEAIENPTPLSVARLEWEHIQRVLAENGGNISATARALNMHRRTLQRKLAKRPVKQ
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]