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The map label for this gene is yafC [C]

Identifier: 186474802

GI number: 186474802

Start: 36108

End: 37196

Strand: Direct

Name: yafC [C]

Synonym: Bphy_0031

Alternate gene names: 186474802

Gene position: 36108-37196 (Clockwise)

Preceding gene: 186474801

Following gene: 186474806

Centisome position: 1.04

GC content: 62.81

Gene sequence:

>1089_bases
ATGGATCATTTGCAGTCGATGCGAGTTTTCGTCAAAGTGGCGGATCTCGGCAGTTTCGCCCGCGCGGCTAGCGCGATGGA
TATTTCAAACGCAGTCGCTACCCGTCACGTCGCCGATCTCGAAGGCCGTCTCGGCACCCGGCTGCTCAACCGCACCACCC
GCAGTCTTTCGCTGACTGAGTCCGGTCAGGTTTATCTGGAACGCGCGCGTCAGATTCTGGATGAGCTCGAAGACGTCGAG
CAGATGGTCGTCGCGCGTAATCACGAGCCTGTCGGCACCCTGCGCATCGTCGCGCCCGTTGTGTTCGGCCTGCACAACCT
TGCGCCCGTGCTCCAGACTTATGCTGAACGCTATCCGAAAGTGATACCCGACGTGACGCTGGTCGATCGCCAGGTCGATC
TCGTCGAAGAAGGTTTCGATGTCGGCGTTGTGATCGCGCGTCATATGCGTAGCGCGAGCATCGTGACACGGCGCCTGACG
ACGGGCTGCATGACCGTCTGCGCAACGCCCGCGTATCTCGACAAGCACGGCACGCCGACCCGCCCCGAACAGCTGCTCGA
GCATCCTTGCCTGTCCCTGCCGTCTGAATACTGGGGCGACGAGCGCGTGTTCACGGGTCCGGACGGCGAGGTGCGCGTGC
GTCCGACCAACGTGATCGTCGCGAACAACACGGAAATGCTGCGTCAGTTCGCGTTGCTCGGCATGGGCATCGCGATCCTG
CCGAGCTACCTGATCGGACGCGACACGACGCGTGGGAAACTGGTGCGTCTGTTGAGCGATTACCGCTTGCCGCAGGTCGA
GATCAACATCGCCTACCCGAGCCGCCGACACTTGCCCGCGAAGGTCCGCACCTTCATTGATCACCTCGTCGAACACTTCA
ACCAGACGCCGAACAGCAAGCTCGGCGAGCAATGGGTGAAGGACGGTGTAGAGCGCGCACCGGCGATGCGCGAATCCACA
GCCATGTCGATGGCGCCCGAAGCCTTCGACGGCGCAGAGCCGCTGTCGAGCCTGCTGGACGGCGACATTCCGGCCAAGCC
GACGCGTACGCTCAATCGCTCGCGCGGCGTTGCTTCGCCGACGCACTGA

Upstream 100 bases:

>100_bases
CACTAACTTAGGCAACTTCTGCAGGATTTCCCTGGTCGTAGGAAAATTCCAAGTGTGCTTCCTGTTCGCGAGGGGAGCGG
TACTACGGCAGGAGTTGTTC

Downstream 100 bases:

>100_bases
CGCGAGTGCTGCGACGTCAGGCAGCGATGGCGTCCACAAGTCAATAAAAAAGCGCAGTCACCGTAAAAGGCGACTGCGCT
TTTTGTTGCAGCCTCGAGGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQTYAERYPKVIPDVTLVDRQVDLVEEGFDVGVVIARHMRSASIVTRRLT
TGCMTVCATPAYLDKHGTPTRPEQLLEHPCLSLPSEYWGDERVFTGPDGEVRVRPTNVIVANNTEMLRQFALLGMGIAIL
PSYLIGRDTTRGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFNQTPNSKLGEQWVKDGVERAPAMREST
AMSMAPEAFDGAEPLSSLLDGDIPAKPTRTLNRSRGVASPTH

Sequences:

>Translated_362_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQTYAERYPKVIPDVTLVDRQVDLVEEGFDVGVVIARHMRSASIVTRRLT
TGCMTVCATPAYLDKHGTPTRPEQLLEHPCLSLPSEYWGDERVFTGPDGEVRVRPTNVIVANNTEMLRQFALLGMGIAIL
PSYLIGRDTTRGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFNQTPNSKLGEQWVKDGVERAPAMREST
AMSMAPEAFDGAEPLSSLLDGDIPAKPTRTLNRSRGVASPTH
>Mature_362_residues
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTESGQVYLERARQILDELEDVE
QMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQTYAERYPKVIPDVTLVDRQVDLVEEGFDVGVVIARHMRSASIVTRRLT
TGCMTVCATPAYLDKHGTPTRPEQLLEHPCLSLPSEYWGDERVFTGPDGEVRVRPTNVIVANNTEMLRQFALLGMGIAIL
PSYLIGRDTTRGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFNQTPNSKLGEQWVKDGVERAPAMREST
AMSMAPEAFDGAEPLSSLLDGDIPAKPTRTLNRSRGVASPTH

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=300, Percent_Identity=33.6666666666667, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=32.6530612244898, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=29.2096219931272, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI87081978, Length=311, Percent_Identity=32.1543408360129, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1787128, Length=302, Percent_Identity=29.1390728476821, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789440, Length=293, Percent_Identity=29.0102389078498, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1787589, Length=290, Percent_Identity=28.9655172413793, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=27.6264591439689, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790011, Length=297, Percent_Identity=24.5791245791246, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=140, Percent_Identity=29.2857142857143, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787879, Length=151, Percent_Identity=31.1258278145695, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790783, Length=255, Percent_Identity=23.921568627451, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788481, Length=191, Percent_Identity=26.7015706806283, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 40199; Mature: 40199

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQTYAERYPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
VIPDVTLVDRQVDLVEEGFDVGVVIARHMRSASIVTRRLTTGCMTVCATPAYLDKHGTPT
HCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
RPEQLLEHPCLSLPSEYWGDERVFTGPDGEVRVRPTNVIVANNTEMLRQFALLGMGIAIL
CHHHHHHCHHHCCCHHHCCCCCEEECCCCCEEEEECEEEEECCHHHHHHHHHHHCCHHHH
PSYLIGRDTTRGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFNQTPNSK
HHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHH
LGEQWVKDGVERAPAMRESTAMSMAPEAFDGAEPLSSLLDGDIPAKPTRTLNRSRGVASP
HHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCC
TH
CC
>Mature Secondary Structure
MDHLQSMRVFVKVADLGSFARAASAMDISNAVATRHVADLEGRLGTRLLNRTTRSLSLTE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCC
SGQVYLERARQILDELEDVEQMVVARNHEPVGTLRIVAPVVFGLHNLAPVLQTYAERYPK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHH
VIPDVTLVDRQVDLVEEGFDVGVVIARHMRSASIVTRRLTTGCMTVCATPAYLDKHGTPT
HCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCC
RPEQLLEHPCLSLPSEYWGDERVFTGPDGEVRVRPTNVIVANNTEMLRQFALLGMGIAIL
CHHHHHHCHHHCCCHHHCCCCCEEECCCCCEEEEECEEEEECCHHHHHHHHHHHCCHHHH
PSYLIGRDTTRGKLVRLLSDYRLPQVEINIAYPSRRHLPAKVRTFIDHLVEHFNQTPNSK
HHHHHCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCHH
LGEQWVKDGVERAPAMRESTAMSMAPEAFDGAEPLSSLLDGDIPAKPTRTLNRSRGVASP
HHHHHHHHHHHHCCHHHHHHHHHCCCHHCCCHHHHHHHHCCCCCCCCCHHHHHCCCCCCC
TH
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]