Click here to switch to the map view.

The map label for this gene is eutR [H]

Identifier: 186474783

GI number: 186474783

Start: 13381

End: 14397

Strand: Direct

Name: eutR [H]

Synonym: Bphy_0011

Alternate gene names: 186474783

Gene position: 13381-14397 (Clockwise)

Preceding gene: 186474780

Following gene: 186474784

Centisome position: 0.38

GC content: 64.5

Gene sequence:

>1017_bases
ATGCCCCATATGACGACCGACCATCATTCCTTGTCCGCGTACCCGCCTGCGTGCCGCGTCGAAACCTGCGTTGCGCACGA
TGCCGATGAGCAGGCGCGCAATCTTCACGGCTGGACGCAGACGTACGACCAGCTCACGGCGGGCCACTTCGTCGGCAGGT
TGACGGGACTGCATCTCGACGACATGCATGTGTTCTGCGAGACGACCAGCCAGACCTTGCGACAGACCTGCGAAGTGCCA
TCGGACGCGTACTGGTTCGGCGTTCCCGCCGACGACGTAAGCATCGGCCGCATCGGTGCGCAGCCGATCAACGGCGACTC
GCTGGCGTTTCAGCGCGGCGGTGTCGAGTTCGAATTGCTCACGCCCGGCGGCTATGCGATCTTCGGTGTGGTGGTGCGCG
GCGCGACGTTGCGACGACACGCGGCTTCCGTCGAACATGCCGATCTGCTCGACCGCGCAACCCACACGGGCGTCATTCCT
ATTGCGATGGAGCACAAGGTGCGCATTTGTGGGCTCTTGCGCAGCATGCTCGACGACACCGCGCGTGCCGCCTTATCGGA
AGGCGCACGGCGCAATCTGCAAGGCTCGGTGTTGTCTTCGCTGTTCGATCTGTGCGCGACGACGGCGCTCGAACCGGTCG
CGATGCCTGCACGTCCGCGCAGACAATGGATCGTCTCGCAAGCGCGCGATTACGTGATCGCGAATCGCGAGCGTCCGGTC
GGCGTGCCGGAACTGTGCGAGCACTTGCACGTCAGCCGCCGCACCTTGCAATACTGCTTTCAGGACGTGCTGGGCCTCGC
GCCCGCAAGCTATCTGCGCGCGATCCGGCTGAACGGTGCGCGCCGCCAACTATGTGGCGCAACACCGGGTGAACTCACGG
TCCAGGACGTCGCGGCCGCGTGGGGCTTCTGGCATCTGAGCCAGTTCGCGACTGACTATCGCAAGCTTTTCGGCGTGCGT
CCGTCCGAAACATTGAAGACCGTTCCCGCGCCCCCGAGTCCGCGACTGGCTCACTAG

Upstream 100 bases:

>100_bases
CGTTGCCCGGAGCAGGCGCGGGATGATCCGTTCGGCACGGGACTTGCGTCGGAGGGCGTCTGTTTGTTCAATGTCACGTG
CAGGTGCATGTCCATCATCG

Downstream 100 bases:

>100_bases
CGCGTCCATCGCCGGGGTTGCGATTGCGTATCCGCTAGAATTGCGGCATGCGCGGCCCCGTCCCGCCGCACGACCCACCA
TCCTCATCGAACATACTGCG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: Ethanolamine operon regulatory protein [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MPHMTTDHHSLSAYPPACRVETCVAHDADEQARNLHGWTQTYDQLTAGHFVGRLTGLHLDDMHVFCETTSQTLRQTCEVP
SDAYWFGVPADDVSIGRIGAQPINGDSLAFQRGGVEFELLTPGGYAIFGVVVRGATLRRHAASVEHADLLDRATHTGVIP
IAMEHKVRICGLLRSMLDDTARAALSEGARRNLQGSVLSSLFDLCATTALEPVAMPARPRRQWIVSQARDYVIANRERPV
GVPELCEHLHVSRRTLQYCFQDVLGLAPASYLRAIRLNGARRQLCGATPGELTVQDVAAAWGFWHLSQFATDYRKLFGVR
PSETLKTVPAPPSPRLAH

Sequences:

>Translated_338_residues
MPHMTTDHHSLSAYPPACRVETCVAHDADEQARNLHGWTQTYDQLTAGHFVGRLTGLHLDDMHVFCETTSQTLRQTCEVP
SDAYWFGVPADDVSIGRIGAQPINGDSLAFQRGGVEFELLTPGGYAIFGVVVRGATLRRHAASVEHADLLDRATHTGVIP
IAMEHKVRICGLLRSMLDDTARAALSEGARRNLQGSVLSSLFDLCATTALEPVAMPARPRRQWIVSQARDYVIANRERPV
GVPELCEHLHVSRRTLQYCFQDVLGLAPASYLRAIRLNGARRQLCGATPGELTVQDVAAAWGFWHLSQFATDYRKLFGVR
PSETLKTVPAPPSPRLAH
>Mature_337_residues
PHMTTDHHSLSAYPPACRVETCVAHDADEQARNLHGWTQTYDQLTAGHFVGRLTGLHLDDMHVFCETTSQTLRQTCEVPS
DAYWFGVPADDVSIGRIGAQPINGDSLAFQRGGVEFELLTPGGYAIFGVVVRGATLRRHAASVEHADLLDRATHTGVIPI
AMEHKVRICGLLRSMLDDTARAALSEGARRNLQGSVLSSLFDLCATTALEPVAMPARPRRQWIVSQARDYVIANRERPVG
VPELCEHLHVSRRTLQYCFQDVLGLAPASYLRAIRLNGARRQLCGATPGELTVQDVAAAWGFWHLSQFATDYRKLFGVRP
SETLKTVPAPPSPRLAH

Specific function: Activates the transcription of the eut operon. Also positively regulates its own transcription. Probably binds ethanolamine and vitamin B12 as effectors [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788778, Length=309, Percent_Identity=39.1585760517799, Blast_Score=208, Evalue=3e-55,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37203; Mature: 37072

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHMTTDHHSLSAYPPACRVETCVAHDADEQARNLHGWTQTYDQLTAGHFVGRLTGLHLD
CCCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
DMHVFCETTSQTLRQTCEVPSDAYWFGVPADDVSIGRIGAQPINGDSLAFQRGGVEFELL
CHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEE
TPGGYAIFGVVVRGATLRRHAASVEHADLLDRATHTGVIPIAMEHKVRICGLLRSMLDDT
CCCCHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHH
ARAALSEGARRNLQGSVLSSLFDLCATTALEPVAMPARPRRQWIVSQARDYVIANRERPV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEECCCCCC
GVPELCEHLHVSRRTLQYCFQDVLGLAPASYLRAIRLNGARRQLCGATPGELTVQDVAAA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHH
WGFWHLSQFATDYRKLFGVRPSETLKTVPAPPSPRLAH
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PHMTTDHHSLSAYPPACRVETCVAHDADEQARNLHGWTQTYDQLTAGHFVGRLTGLHLD
CCCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCC
DMHVFCETTSQTLRQTCEVPSDAYWFGVPADDVSIGRIGAQPINGDSLAFQRGGVEFELL
CHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEEE
TPGGYAIFGVVVRGATLRRHAASVEHADLLDRATHTGVIPIAMEHKVRICGLLRSMLDDT
CCCCHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHH
ARAALSEGARRNLQGSVLSSLFDLCATTALEPVAMPARPRRQWIVSQARDYVIANRERPV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHEEECCCCCC
GVPELCEHLHVSRRTLQYCFQDVLGLAPASYLRAIRLNGARRQLCGATPGELTVQDVAAA
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHHHCCCCCCCCHHHHHHHH
WGFWHLSQFATDYRKLFGVRPSETLKTVPAPPSPRLAH
HHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8300522; 9205837; 9278503 [H]