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The map label for this gene is yngJ [H]

Identifier: 183222678

GI number: 183222678

Start: 3441913

End: 3443088

Strand: Reverse

Name: yngJ [H]

Synonym: LEPBI_I3333

Alternate gene names: 183222678

Gene position: 3443088-3441913 (Counterclockwise)

Preceding gene: 183222679

Following gene: 183222677

Centisome position: 95.65

GC content: 43.71

Gene sequence:

>1176_bases
ATGGACTTTGAAATTCCCCAAGAAGTAGAAACACTTCGTAAAAATATCCAATCCTTTATCACAGAAGAAATCATTCCTCT
GGAAAAACATTATGACTATGAAAAAGGTCGGATGCCGGAAGATATCAACCAACAAGCACGCGCTAAAGTAAAGGCAGCTG
GGTTTTGGACTCCACACCTTCCAAAAAAAGAAGGTGGATTGGGCTTGGATTTAATTGGAACTTGTATCATTTTTAGTGAA
CTCGGTCGTTCTCCCATAGCACCTTATATATTCAATTGTGATGCACCTGATGAAGGGAATATGCATTTGTTGTCTCTTGC
CGCGACAGAAAAACAAAAAGAATTGATCTTACATCCCCTGATCAAAGGAGAACTCCGCACTGGTTTTGCCATGACAGAAC
CATCACCAGGTGCTGGATCTGATCCAACATCCCTTCAAACCAATGCGGAAAAACAAGGGGATAAGTTTATTTTAAACGGA
CGAAAGTGGTATTGTACGGGAGCCAACGGAGCCAAGTATCTCATTGTTATGGCAAAGGTGAATGGGAGTTTTCGTAAAAC
CACAATGTTCCTTGTGCCTACCGATGCAAAAGGTTATACGATGGTTCGCGAAATTGAACTGATGGGATCTCATGGACCAG
GTGGTCACTGTGAACTCAATTTTGAAAATGTGGAAGTTCCAGAGGATATGGTTCTTGGTAGAGTGGGAGAGGGGTTTCGG
TTGTCGCAAGAAAGGTTGGGACCTGCTCGCCTTACGCATTGCATGCGATGGACTGGTATGGCTAGACGAGCACTTTCGAT
AGCTCGAAGTTATGCGAAAGAAAGAGAAGTGTTTAACGCAAGGATCGCAGACCACCAAGGGATCCAATGGATGTTTGCCG
AACGTGCAACAGAAATTGAGATGGCATTTTTATTAACTCTCAAAGCGGCTTGGCTCTTAAAAACAGGAAAAGATGCAAGG
CAAGAAACATCGATGGCAAAATGGAAAGTGAGTGAGTCATTATGTAATACCATCGATATGGCCATCCAAATTTGTGGGGG
CAAAGGTTATTCAAGGGACCTTCCCCTTGAATTATTCTACCGAGATGCAAGGGCCGCAAGGATCGCCGACGGCCCATCGG
AGGTGCATAAAATGGTCATTGGACGTAACTATGTTTCGGAGAAGTGGGATTTTTAA

Upstream 100 bases:

>100_bases
TTTGAAATTAGAAGAAATTCAAAAAGACAAAGACCTATTTTTCATTCACACTAAAAAAAGATTTTACGACCTTTCTTGAT
TGTGTTACTTCTTGGAAACA

Downstream 100 bases:

>100_bases
GGGAACATGGACATCAAAGAACTACAAGAAAAAGTAGAACTTCACTTAACATCGATTTGGCAAACTCCAGTGAAAGTATC
AGAAATCTTTCATTTAAGTG

Product: putative acyl-CoA dehydrogenase

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MDFEIPQEVETLRKNIQSFITEEIIPLEKHYDYEKGRMPEDINQQARAKVKAAGFWTPHLPKKEGGLGLDLIGTCIIFSE
LGRSPIAPYIFNCDAPDEGNMHLLSLAATEKQKELILHPLIKGELRTGFAMTEPSPGAGSDPTSLQTNAEKQGDKFILNG
RKWYCTGANGAKYLIVMAKVNGSFRKTTMFLVPTDAKGYTMVREIELMGSHGPGGHCELNFENVEVPEDMVLGRVGEGFR
LSQERLGPARLTHCMRWTGMARRALSIARSYAKEREVFNARIADHQGIQWMFAERATEIEMAFLLTLKAAWLLKTGKDAR
QETSMAKWKVSESLCNTIDMAIQICGGKGYSRDLPLELFYRDARAARIADGPSEVHKMVIGRNYVSEKWDF

Sequences:

>Translated_391_residues
MDFEIPQEVETLRKNIQSFITEEIIPLEKHYDYEKGRMPEDINQQARAKVKAAGFWTPHLPKKEGGLGLDLIGTCIIFSE
LGRSPIAPYIFNCDAPDEGNMHLLSLAATEKQKELILHPLIKGELRTGFAMTEPSPGAGSDPTSLQTNAEKQGDKFILNG
RKWYCTGANGAKYLIVMAKVNGSFRKTTMFLVPTDAKGYTMVREIELMGSHGPGGHCELNFENVEVPEDMVLGRVGEGFR
LSQERLGPARLTHCMRWTGMARRALSIARSYAKEREVFNARIADHQGIQWMFAERATEIEMAFLLTLKAAWLLKTGKDAR
QETSMAKWKVSESLCNTIDMAIQICGGKGYSRDLPLELFYRDARAARIADGPSEVHKMVIGRNYVSEKWDF
>Mature_391_residues
MDFEIPQEVETLRKNIQSFITEEIIPLEKHYDYEKGRMPEDINQQARAKVKAAGFWTPHLPKKEGGLGLDLIGTCIIFSE
LGRSPIAPYIFNCDAPDEGNMHLLSLAATEKQKELILHPLIKGELRTGFAMTEPSPGAGSDPTSLQTNAEKQGDKFILNG
RKWYCTGANGAKYLIVMAKVNGSFRKTTMFLVPTDAKGYTMVREIELMGSHGPGGHCELNFENVEVPEDMVLGRVGEGFR
LSQERLGPARLTHCMRWTGMARRALSIARSYAKEREVFNARIADHQGIQWMFAERATEIEMAFLLTLKAAWLLKTGKDAR
QETSMAKWKVSESLCNTIDMAIQICGGKGYSRDLPLELFYRDARAARIADGPSEVHKMVIGRNYVSEKWDF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI38505218, Length=385, Percent_Identity=35.3246753246753, Blast_Score=229, Evalue=2e-60,
Organism=Homo sapiens, GI211971008, Length=392, Percent_Identity=35.969387755102, Blast_Score=221, Evalue=9e-58,
Organism=Homo sapiens, GI48976061, Length=392, Percent_Identity=35.969387755102, Blast_Score=221, Evalue=1e-57,
Organism=Homo sapiens, GI4501859, Length=378, Percent_Identity=32.010582010582, Blast_Score=182, Evalue=7e-46,
Organism=Homo sapiens, GI4557231, Length=397, Percent_Identity=29.7229219143577, Blast_Score=172, Evalue=7e-43,
Organism=Homo sapiens, GI187960098, Length=397, Percent_Identity=29.7229219143577, Blast_Score=171, Evalue=8e-43,
Organism=Homo sapiens, GI4557233, Length=391, Percent_Identity=30.690537084399, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI21361497, Length=387, Percent_Identity=31.266149870801, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI7656849, Length=392, Percent_Identity=27.5510204081633, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI4501857, Length=390, Percent_Identity=27.6923076923077, Blast_Score=132, Evalue=7e-31,
Organism=Homo sapiens, GI226958412, Length=388, Percent_Identity=28.0927835051546, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI226958414, Length=380, Percent_Identity=28.1578947368421, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI76496475, Length=388, Percent_Identity=26.5463917525773, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI4557235, Length=388, Percent_Identity=26.5463917525773, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4503943, Length=291, Percent_Identity=28.5223367697594, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI7669494, Length=260, Percent_Identity=30, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI87081958, Length=394, Percent_Identity=27.6649746192893, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1786223, Length=325, Percent_Identity=28.9230769230769, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI87082384, Length=266, Percent_Identity=25.9398496240602, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562446, Length=360, Percent_Identity=36.9444444444444, Blast_Score=216, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17570075, Length=393, Percent_Identity=33.0788804071247, Blast_Score=207, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17534899, Length=392, Percent_Identity=31.3775510204082, Blast_Score=174, Evalue=6e-44,
Organism=Caenorhabditis elegans, GI17569725, Length=393, Percent_Identity=29.0076335877863, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17508101, Length=381, Percent_Identity=27.5590551181102, Blast_Score=154, Evalue=6e-38,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=29.1666666666667, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17538396, Length=385, Percent_Identity=29.3506493506493, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17533517, Length=394, Percent_Identity=25.6345177664975, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71990804, Length=280, Percent_Identity=30, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17551932, Length=372, Percent_Identity=24.1935483870968, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=24.9329758713137, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=288, Percent_Identity=28.4722222222222, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=28.3261802575107, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=26.4285714285714, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=221, Percent_Identity=27.1493212669683, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17534353, Length=277, Percent_Identity=24.5487364620939, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646207, Length=382, Percent_Identity=33.5078534031414, Blast_Score=196, Evalue=3e-50,
Organism=Drosophila melanogaster, GI21356377, Length=380, Percent_Identity=31.8421052631579, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24660351, Length=386, Percent_Identity=30.8290155440415, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=28.1501340482574, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=29.5629820051414, Blast_Score=143, Evalue=2e-34,
Organism=Drosophila melanogaster, GI281363737, Length=383, Percent_Identity=27.6762402088773, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920834, Length=281, Percent_Identity=27.7580071174377, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 43927; Mature: 43927

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFEIPQEVETLRKNIQSFITEEIIPLEKHYDYEKGRMPEDINQQARAKVKAAGFWTPHL
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PKKEGGLGLDLIGTCIIFSELGRSPIAPYIFNCDAPDEGNMHLLSLAATEKQKELILHPL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHH
IKGELRTGFAMTEPSPGAGSDPTSLQTNAEKQGDKFILNGRKWYCTGANGAKYLIVMAKV
HHCHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCEEEEEEEEC
NGSFRKTTMFLVPTDAKGYTMVREIELMGSHGPGGHCELNFENVEVPEDMVLGRVGEGFR
CCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHCCCCCCC
LSQERLGPARLTHCMRWTGMARRALSIARSYAKEREVFNARIADHQGIQWMFAERATEIE
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCHHH
MAFLLTLKAAWLLKTGKDARQETSMAKWKVSESLCNTIDMAIQICGGKGYSRDLPLELFY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHEE
RDARAARIADGPSEVHKMVIGRNYVSEKWDF
CCCCHHCCCCCHHHHHHHHHCCCHHHHCCCC
>Mature Secondary Structure
MDFEIPQEVETLRKNIQSFITEEIIPLEKHYDYEKGRMPEDINQQARAKVKAAGFWTPHL
CCCCCHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
PKKEGGLGLDLIGTCIIFSELGRSPIAPYIFNCDAPDEGNMHLLSLAATEKQKELILHPL
CCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEEECCCHHHHHHHHHH
IKGELRTGFAMTEPSPGAGSDPTSLQTNAEKQGDKFILNGRKWYCTGANGAKYLIVMAKV
HHCHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCEEEEEEEEC
NGSFRKTTMFLVPTDAKGYTMVREIELMGSHGPGGHCELNFENVEVPEDMVLGRVGEGFR
CCCEEEEEEEEEECCCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCHHHHHHCCCCCCC
LSQERLGPARLTHCMRWTGMARRALSIARSYAKEREVFNARIADHQGIQWMFAERATEIE
CCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHCCCHHH
MAFLLTLKAAWLLKTGKDARQETSMAKWKVSESLCNTIDMAIQICGGKGYSRDLPLELFY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHEE
RDARAARIADGPSEVHKMVIGRNYVSEKWDF
CCCCHHCCCCCHHHHHHHHHCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]