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The map label for this gene is coaX [H]

Identifier: 183222617

GI number: 183222617

Start: 3385538

End: 3386329

Strand: Reverse

Name: coaX [H]

Synonym: LEPBI_I3272

Alternate gene names: 183222617

Gene position: 3386329-3385538 (Counterclockwise)

Preceding gene: 183222618

Following gene: 183222613

Centisome position: 94.07

GC content: 38.13

Gene sequence:

>792_bases
ATGTCAGAATCACCACTATTACTTGTTATCGACGTTGGGAATACCAATACTGTATTTGGAGTTTTTCGAGAAGGTGAAGA
AACGCCTGATTTTCACAAAAGAACTGTTACGCGAAGGGATCGAACTTCAGACGAACTTGGACTTTTTTTGAAAGGATTTT
TAACTCAAGAAAACGTAAAAGCTGATCGAGTGAAAAAAGCGATTTATTCCAGTGTTGTTCCTTCACTCAATCCAATTGTT
GAAAGAATGTTAGAAGATTGGTTTGATGTGAATCCACTCCGAGTTCATTACCAAATGAATTTAAATTTCGGTATCAGTTA
TCCACGACCATTTGAAATCGGAGCCGATCGGTTAGTAAACGCTGCTTATTGTGCAAAAATGTATCCAGGTAAAAAAGCGA
TTCTTGTCGATTTGGGAACAGCGACTACATTTTGTGTCATCAGCGAAAAACCTGAATACATTGGTGGAGTCATCGCACCT
GGTTTAAAAATATCTATGGATGCCTTAACAAGAAATACGGCTCAACTTCCACCAATTGTCTTCGGATCTCCCAAACATGT
ACTTGGTGATTCAACTGTAGAATCAATCCAAGCTGGATTTTTCTTTGGTTGGATTGGACTCTTGAAAGAAATTGTCCGAG
CCATTAAAGACGAACACCCAGGAGATTATGTGGTAGTTGGGACAGGTGGACTTGTCACTACGATTCATGCATCGCATAAC
CAAGTATTTGATGAAATTGATCCTATGATGACATTAAAAGGATTAAAGATTTTAGCGGATTTAAATTCCTAA

Upstream 100 bases:

>100_bases
AGTTTTGGGAATTGATGAATTAGGATTCCTTCTCATTATGACTGAAACTGGTCAAAAGATTGAACTGATGGACACGTCAC
CAAAATTTCGGATAATATAA

Downstream 100 bases:

>100_bases
TTCTTTTACCTTCATTTGGTAGAACGAAATGAATTACTTCTTCGTATAAACAATGGTTTTGTAGTGCAACCAATGGTTGG
ATGGAACAGGAATTTCCCAT

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSESPLLLVIDVGNTNTVFGVFREGEETPDFHKRTVTRRDRTSDELGLFLKGFLTQENVKADRVKKAIYSSVVPSLNPIV
ERMLEDWFDVNPLRVHYQMNLNFGISYPRPFEIGADRLVNAAYCAKMYPGKKAILVDLGTATTFCVISEKPEYIGGVIAP
GLKISMDALTRNTAQLPPIVFGSPKHVLGDSTVESIQAGFFFGWIGLLKEIVRAIKDEHPGDYVVVGTGGLVTTIHASHN
QVFDEIDPMMTLKGLKILADLNS

Sequences:

>Translated_263_residues
MSESPLLLVIDVGNTNTVFGVFREGEETPDFHKRTVTRRDRTSDELGLFLKGFLTQENVKADRVKKAIYSSVVPSLNPIV
ERMLEDWFDVNPLRVHYQMNLNFGISYPRPFEIGADRLVNAAYCAKMYPGKKAILVDLGTATTFCVISEKPEYIGGVIAP
GLKISMDALTRNTAQLPPIVFGSPKHVLGDSTVESIQAGFFFGWIGLLKEIVRAIKDEHPGDYVVVGTGGLVTTIHASHN
QVFDEIDPMMTLKGLKILADLNS
>Mature_262_residues
SESPLLLVIDVGNTNTVFGVFREGEETPDFHKRTVTRRDRTSDELGLFLKGFLTQENVKADRVKKAIYSSVVPSLNPIVE
RMLEDWFDVNPLRVHYQMNLNFGISYPRPFEIGADRLVNAAYCAKMYPGKKAILVDLGTATTFCVISEKPEYIGGVIAPG
LKISMDALTRNTAQLPPIVFGSPKHVLGDSTVESIQAGFFFGWIGLLKEIVRAIKDEHPGDYVVVGTGGLVTTIHASHNQ
VFDEIDPMMTLKGLKILADLNS

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 29072; Mature: 28941

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESPLLLVIDVGNTNTVFGVFREGEETPDFHKRTVTRRDRTSDELGLFLKGFLTQENVK
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCH
ADRVKKAIYSSVVPSLNPIVERMLEDWFDVNPLRVHYQMNLNFGISYPRPFEIGADRLVN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHH
AAYCAKMYPGKKAILVDLGTATTFCVISEKPEYIGGVIAPGLKISMDALTRNTAQLPPIV
HHHHHHCCCCCEEEEEEECCCEEEEEECCCCHHHCCEECCCCEEEHHHHHCCCCCCCCEE
FGSPKHVLGDSTVESIQAGFFFGWIGLLKEIVRAIKDEHPGDYVVVGTGGLVTTIHASHN
ECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCHH
QVFDEIDPMMTLKGLKILADLNS
HHHHHHHHHHHHHHHEEEEECCC
>Mature Secondary Structure 
SESPLLLVIDVGNTNTVFGVFREGEETPDFHKRTVTRRDRTSDELGLFLKGFLTQENVK
CCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCCH
ADRVKKAIYSSVVPSLNPIVERMLEDWFDVNPLRVHYQMNLNFGISYPRPFEIGADRLVN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCCCCCCCHHHHHH
AAYCAKMYPGKKAILVDLGTATTFCVISEKPEYIGGVIAPGLKISMDALTRNTAQLPPIV
HHHHHHCCCCCEEEEEEECCCEEEEEECCCCHHHCCEECCCCEEEHHHHHCCCCCCCCEE
FGSPKHVLGDSTVESIQAGFFFGWIGLLKEIVRAIKDEHPGDYVVVGTGGLVTTIHASHN
ECCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCHH
QVFDEIDPMMTLKGLKILADLNS
HHHHHHHHHHHHHHHEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA