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The map label for this gene is slyD [H]

Identifier: 183222472

GI number: 183222472

Start: 3240807

End: 3241298

Strand: Direct

Name: slyD [H]

Synonym: LEPBI_I3126

Alternate gene names: 183222472

Gene position: 3240807-3241298 (Clockwise)

Preceding gene: 183222470

Following gene: 183222473

Centisome position: 90.03

GC content: 44.11

Gene sequence:

>492_bases
ATGAATATGTCAAAAACCATCAGCAAAGGAATGGTTGTAGGATTTTCCTATCACCTCAAGAACGCCCAGGGAGAAACTCT
GGACCAATCAGACGAACCGCTATTATACCTCCACGGCTGGCAAAATATCATCCCTGGACTGGAAAAAGAATTGGAAGGTC
TTGTGAACGGAGATTCTAAAAATGTCACAGTTCCACCTGAAGAAGGTTATGGGACATATAACGAAGCCCTCATTTTCCAA
GTTCCCAAAACAGAACTTCCTGCCGAAGCAGAACTCGAAGTGGGAATGGAATTCCAAACCGACACACCAGAAGGTAGAAT
GATTCTATATCTCCAAGAAGTACGAGATGCGGATGTAATCCTAAACGGCAATCACCCGTTAGCTGGAGAAACCCTTCATT
TTGATGTCACAATCAAATCGATTCGTGAAGCAACAGATGAAGAAAAACAACACGGACACGTACATGGTCCAGGTGGACAC
CACCACCACTAA

Upstream 100 bases:

>100_bases
ATTCATAGATATTGATATTTCCAGGGTTCAATTTCTTTGATAACAATATGGTACCAACCTTTTATTCGGTTGCCGTATTT
TTTTCCGTATATAGAGTGTA

Downstream 100 bases:

>100_bases
AAACGAAATCTTTTTCGTTATTTTCCCTCTGAGTCTTCTTTCGGATTGCTTTTTTTAGAAAGGGTTATTACACTGACAGA
AGATTCAGAGTATTGTTGAT

Product: FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MNMSKTISKGMVVGFSYHLKNAQGETLDQSDEPLLYLHGWQNIIPGLEKELEGLVNGDSKNVTVPPEEGYGTYNEALIFQ
VPKTELPAEAELEVGMEFQTDTPEGRMILYLQEVRDADVILNGNHPLAGETLHFDVTIKSIREATDEEKQHGHVHGPGGH
HHH

Sequences:

>Translated_163_residues
MNMSKTISKGMVVGFSYHLKNAQGETLDQSDEPLLYLHGWQNIIPGLEKELEGLVNGDSKNVTVPPEEGYGTYNEALIFQ
VPKTELPAEAELEVGMEFQTDTPEGRMILYLQEVRDADVILNGNHPLAGETLHFDVTIKSIREATDEEKQHGHVHGPGGH
HHH
>Mature_163_residues
MNMSKTISKGMVVGFSYHLKNAQGETLDQSDEPLLYLHGWQNIIPGLEKELEGLVNGDSKNVTVPPEEGYGTYNEALIFQ
VPKTELPAEAELEVGMEFQTDTPEGRMILYLQEVRDADVILNGNHPLAGETLHFDVTIKSIREATDEEKQHGHVHGPGGH
HHH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=144, Percent_Identity=40.9722222222222, Blast_Score=107, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18132; Mature: 18132

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMSKTISKGMVVGFSYHLKNAQGETLDQSDEPLLYLHGWQNIIPGLEKELEGLVNGDSK
CCCHHHHCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCHHHCCCHHHHHHHHHCCCCC
NVTVPPEEGYGTYNEALIFQVPKTELPAEAELEVGMEFQTDTPEGRMILYLQEVRDADVI
CEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEECEEEECCCCCCEEEEEEECCCCCEEE
LNGNHPLAGETLHFDVTIKSIREATDEEKQHGHVHGPGGHHHH
ECCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNMSKTISKGMVVGFSYHLKNAQGETLDQSDEPLLYLHGWQNIIPGLEKELEGLVNGDSK
CCCHHHHCCCEEEEEEEEECCCCCCCCCCCCCCEEEEECCHHHCCCHHHHHHHHHCCCCC
NVTVPPEEGYGTYNEALIFQVPKTELPAEAELEVGMEFQTDTPEGRMILYLQEVRDADVI
CEEECCCCCCCCCCCEEEEEECCCCCCCCCEEEECEEEECCCCCCEEEEEEECCCCCEEE
LNGNHPLAGETLHFDVTIKSIREATDEEKQHGHVHGPGGHHHH
ECCCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]