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The map label for this gene is yogA [H]

Identifier: 183222463

GI number: 183222463

Start: 3230688

End: 3231935

Strand: Reverse

Name: yogA [H]

Synonym: LEPBI_I3117

Alternate gene names: 183222463

Gene position: 3231935-3230688 (Counterclockwise)

Preceding gene: 183222464

Following gene: 183222462

Centisome position: 89.78

GC content: 44.71

Gene sequence:

>1248_bases
ATGAGCAACGTAGAAATCGTACCAGTAGGGGAACTACCTCCTATTGGAGTCGTGCCAAAAAAAATGCACGCACAGGTCAT
TCGCCCGGAACGTTACGGCGAACCGAAAACTTCTTTCCAATCAGAAGTCATTGATGTTCCGGAGATCGGTCCGAACGAAG
TTCTCGTGGCCACTATGGCTGCTGGGGTAAACTATAACAATGTTTGGGCGGCCTTAGGTTACCCTGTTGATGTCATTGCG
GCACGTAATAAAAAAGGGGAACCTGAAAAGTTTCACATTGGTGGCTCTGACGCATCTGGTATCGTTTACAAAGTTGGTTC
TGAAGTTAAAAATGTAAAAGTGGGGGACGAAGTAGTTGTCCACTGTGCGATGTGGGATCCGAAAGACCCATGGGTTCTTT
CTGGAAAAGACCCAATGTATGCACCTTCACAAATCATCTGGGGATACGAATCAAACTGGGGATCCTTTGCACAGTTTTGC
AAAGTGCAAGACCACCAGTGCCTACCACGTCCTCAACACCTAACATGGGAAGCATCTGCAGCCTATATGTTAGTTGCTGC
AACCGCCTACAGAATGTTACACCACTGGAAACCGAACGATGTAAAACCTGGTGATGTTGTTTTGATATGGGGTGGAGCTG
GTGGACTCGGTGCTATGGCAATCCAAATCGTAAAAGCAGCTGGTGGAATTCCAATCGCAGTTGTATCATCTGATGATAAA
ATTGAATTCTGTAAAAACTTAGGTGCTACTGGTGTCATCAACCGTAATAAGTTCAAACATTGGGGTGCTCTCACTTCTGA
AATCAACAAACCAGAAGCTTTTGTTGAGTGGACCAAACAAGCACGTGAGTTTGGAAAAGCAATTTGGGACATCGCAGGCA
AAGGCAAAAATCCACAAATCGTTTTTGAACACCCAGGCGAAACAACACTTCCTACTTCTGTATTTGTATGTGAAACTGGT
GGTATGGTTGTGATATGTGCGGGAACAACAGGTTTCAATGCAACGGGTGATTTACGTTACCTTTGGATGAGACAAAAACG
TCTGCAAGGTTCTCACTTCGCAAACGATGACAACTGCCGTGACCTCAACCAATTGGTGATTGATAAAAAAGTGGATCCAG
TATTGGCTCAAACGTTTACTTTCGATCAAACAGGTGAATGCCACCAATTGATGCGTGAAAACAAACACCCAGCAGGAAAC
ATGTCAATCCTCGTTGGTGCAAAAACGACAGGTTTGGGAAAGAAGTAA

Upstream 100 bases:

>100_bases
ACATTTGCCTTCTCGATGGAGTGGGGAAGCGATTGACATTTCATGCCTTTTTTAAAACGTTCTAAGAAACTGTATAAATC
TTAATCGTAAAAGGTAATCT

Downstream 100 bases:

>100_bases
TTTCATTCCGAACGTGTATTTAGAGTACATGTCCCCGCCCGTATCGAACTGGGTGGGGTTATCCACCCGCCACCCAATGG
CTCCATTTACCACACAACAT

Product: alcohol dehydrogenase

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MSNVEIVPVGELPPIGVVPKKMHAQVIRPERYGEPKTSFQSEVIDVPEIGPNEVLVATMAAGVNYNNVWAALGYPVDVIA
ARNKKGEPEKFHIGGSDASGIVYKVGSEVKNVKVGDEVVVHCAMWDPKDPWVLSGKDPMYAPSQIIWGYESNWGSFAQFC
KVQDHQCLPRPQHLTWEASAAYMLVAATAYRMLHHWKPNDVKPGDVVLIWGGAGGLGAMAIQIVKAAGGIPIAVVSSDDK
IEFCKNLGATGVINRNKFKHWGALTSEINKPEAFVEWTKQAREFGKAIWDIAGKGKNPQIVFEHPGETTLPTSVFVCETG
GMVVICAGTTGFNATGDLRYLWMRQKRLQGSHFANDDNCRDLNQLVIDKKVDPVLAQTFTFDQTGECHQLMRENKHPAGN
MSILVGAKTTGLGKK

Sequences:

>Translated_415_residues
MSNVEIVPVGELPPIGVVPKKMHAQVIRPERYGEPKTSFQSEVIDVPEIGPNEVLVATMAAGVNYNNVWAALGYPVDVIA
ARNKKGEPEKFHIGGSDASGIVYKVGSEVKNVKVGDEVVVHCAMWDPKDPWVLSGKDPMYAPSQIIWGYESNWGSFAQFC
KVQDHQCLPRPQHLTWEASAAYMLVAATAYRMLHHWKPNDVKPGDVVLIWGGAGGLGAMAIQIVKAAGGIPIAVVSSDDK
IEFCKNLGATGVINRNKFKHWGALTSEINKPEAFVEWTKQAREFGKAIWDIAGKGKNPQIVFEHPGETTLPTSVFVCETG
GMVVICAGTTGFNATGDLRYLWMRQKRLQGSHFANDDNCRDLNQLVIDKKVDPVLAQTFTFDQTGECHQLMRENKHPAGN
MSILVGAKTTGLGKK
>Mature_414_residues
SNVEIVPVGELPPIGVVPKKMHAQVIRPERYGEPKTSFQSEVIDVPEIGPNEVLVATMAAGVNYNNVWAALGYPVDVIAA
RNKKGEPEKFHIGGSDASGIVYKVGSEVKNVKVGDEVVVHCAMWDPKDPWVLSGKDPMYAPSQIIWGYESNWGSFAQFCK
VQDHQCLPRPQHLTWEASAAYMLVAATAYRMLHHWKPNDVKPGDVVLIWGGAGGLGAMAIQIVKAAGGIPIAVVSSDDKI
EFCKNLGATGVINRNKFKHWGALTSEINKPEAFVEWTKQAREFGKAIWDIAGKGKNPQIVFEHPGETTLPTSVFVCETGG
MVVICAGTTGFNATGDLRYLWMRQKRLQGSHFANDDNCRDLNQLVIDKKVDPVLAQTFTFDQTGECHQLMRENKHPAGNM
SILVGAKTTGLGKK

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790485, Length=387, Percent_Identity=25.3229974160207, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17507255, Length=396, Percent_Identity=23.989898989899, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=248, Percent_Identity=28.2258064516129, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17562876, Length=255, Percent_Identity=29.0196078431373, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323729, Length=241, Percent_Identity=29.045643153527, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 45375; Mature: 45243

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVEIVPVGELPPIGVVPKKMHAQVIRPERYGEPKTSFQSEVIDVPEIGPNEVLVATMA
CCCCEEEECCCCCCCCCCCCHHHHEEECHHHCCCCCCCHHHHCCCCCCCCCCCEEEEEEE
AGVNYNNVWAALGYPVDVIAARNKKGEPEKFHIGGSDASGIVYKVGSEVKNVKVGDEVVV
CCCCCCCEEEECCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCCEECCCEEEE
HCAMWDPKDPWVLSGKDPMYAPSQIIWGYESNWGSFAQFCKVQDHQCLPRPQHLTWEASA
EEEECCCCCCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCEEEECCH
AYMLVAATAYRMLHHWKPNDVKPGDVVLIWGGAGGLGAMAIQIVKAAGGIPIAVVSSDDK
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCH
IEFCKNLGATGVINRNKFKHWGALTSEINKPEAFVEWTKQAREFGKAIWDIAGKGKNPQI
HHHHHCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VFEHPGETTLPTSVFVCETGGMVVICAGTTGFNATGDLRYLWMRQKRLQGSHFANDDNCR
EEECCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCHH
DLNQLVIDKKVDPVLAQTFTFDQTGECHQLMRENKHPAGNMSILVGAKTTGLGKK
HHHHHHHCCCCCHHHHHEECCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure 
SNVEIVPVGELPPIGVVPKKMHAQVIRPERYGEPKTSFQSEVIDVPEIGPNEVLVATMA
CCCEEEECCCCCCCCCCCCHHHHEEECHHHCCCCCCCHHHHCCCCCCCCCCCEEEEEEE
AGVNYNNVWAALGYPVDVIAARNKKGEPEKFHIGGSDASGIVYKVGSEVKNVKVGDEVVV
CCCCCCCEEEECCCCEEEEEECCCCCCCCEEEECCCCCCCEEEEECCCCCCEECCCEEEE
HCAMWDPKDPWVLSGKDPMYAPSQIIWGYESNWGSFAQFCKVQDHQCLPRPQHLTWEASA
EEEECCCCCCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCEEEECCH
AYMLVAATAYRMLHHWKPNDVKPGDVVLIWGGAGGLGAMAIQIVKAAGGIPIAVVSSDDK
HHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCH
IEFCKNLGATGVINRNKFKHWGALTSEINKPEAFVEWTKQAREFGKAIWDIAGKGKNPQI
HHHHHCCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
VFEHPGETTLPTSVFVCETGGMVVICAGTTGFNATGDLRYLWMRQKRLQGSHFANDDNCR
EEECCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCEEEEEEHHHHCCCCCCCCCCCHH
DLNQLVIDKKVDPVLAQTFTFDQTGECHQLMRENKHPAGNMSILVGAKTTGLGKK
HHHHHHHCCCCCHHHHHEECCCCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]