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The map label for this gene is hcr [C]

Identifier: 183222451

GI number: 183222451

Start: 3221584

End: 3222669

Strand: Reverse

Name: hcr [C]

Synonym: LEPBI_I3105

Alternate gene names: 183222451

Gene position: 3222669-3221584 (Counterclockwise)

Preceding gene: 183222453

Following gene: 183222450

Centisome position: 89.53

GC content: 37.57

Gene sequence:

>1086_bases
ATGAAATCATTTCCTTTTATCTACAACGAACCGCGGGAATTCTTAAGTTCCTTACAACCCAAAGAGTGGGCCAATTTTTT
CTTGGGTGAATTGAACCCTAGATTTTCTGTCACAGCCACAAAAGCAAAAGTCATCGAAGTGAAAGAGGAGACTTCCGATT
CCAAAACAATCGTTTTGAAACCAAACTGGTTATGGAAAGGATTTGCATCTGGCCAACATGTGCCAGTGACTGTGGAAATT
GCGGGAAGAAGGGTCACTCGATTTTATTCCTTATCATCTCACCCAAATGACAAGTACCTCCAAATTACCGTAAAACGCCA
GAAAGGTGGTCTTGTTTCAAACTTTATCAATCAGAACATCAAAAAAGGTGACATTCTGGAATTGGGTGAAGCATCCGGTG
ACTTTGTTCTCACAAAAGAGCTACCAAAAGATTTGTTGTTCTTGGCAGGTGGAAGTGGAATCACACCAATCCATTCCATT
CTCAGAAGTTTACAAACGTTAAACTATACTGGAAAAGCGACTCTATTGTATTTTGTAAGATCCTATGATGATATTATCTT
CAAATCATCCTTCGATTCCATGCAAAAGAATTCAAATTGGTTAACAGTTCACTATGTATTTTCTGATATTCCTAAAGAAG
GGTATGCTTCGGGTTTTTTATCAAAAGAGATTTTAGAAACCTATGTTCCAAACTTAAAATCATCCTCCGTTTATGTCTGC
GGACCTTCTCCAATGCAAACGAAAGCATTGTCTTTATTAGAAGGATTACCTGTAAAATCCGAGTTATTCCTCCTTCCTGG
ACAAAATGTAGGCAAAGTGAAAAAAGAAGGAACAGTAGATGTATTTTTAACTTTAAGTCACAAAACCATCCAAGTAAAAG
GGGAACGTTCCATATTAGAAGAGTTAGAAGAACAAGGGATTTATCCGCAAAGTGGATGCCGTATGGGAATTTGCCATACA
TGTGTTTGTAAAAAACAAACAGGTTCCATTACGGATCTTTCAAATGGGGAAACTTCTCAATTGGGCGAAGAAAATATCCA
AATCTGCGTTTCTAGAGCTGAATCCAATTTGGAATTAGAACTATAA

Upstream 100 bases:

>100_bases
AAAAATCCTTCTTTTGGGTTGACATAGTTAACGATGTAAGTTAACACTATTAGATAAATTCGTGAACAAGTGTTCACTTA
AATGCGAAAACGAGGCGAAA

Downstream 100 bases:

>100_bases
CTTTTAATCACAAAGGAAATTGAAATTATCATAGGAAAACAAAATGAGAACAATTAGTAAAAAATTAAACAAAGAAGAAA
TTGAAGCATTCGGAAAAGAA

Product: putative ferredoxin--NAD(+) reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MKSFPFIYNEPREFLSSLQPKEWANFFLGELNPRFSVTATKAKVIEVKEETSDSKTIVLKPNWLWKGFASGQHVPVTVEI
AGRRVTRFYSLSSHPNDKYLQITVKRQKGGLVSNFINQNIKKGDILELGEASGDFVLTKELPKDLLFLAGGSGITPIHSI
LRSLQTLNYTGKATLLYFVRSYDDIIFKSSFDSMQKNSNWLTVHYVFSDIPKEGYASGFLSKEILETYVPNLKSSSVYVC
GPSPMQTKALSLLEGLPVKSELFLLPGQNVGKVKKEGTVDVFLTLSHKTIQVKGERSILEELEEQGIYPQSGCRMGICHT
CVCKKQTGSITDLSNGETSQLGEENIQICVSRAESNLELEL

Sequences:

>Translated_361_residues
MKSFPFIYNEPREFLSSLQPKEWANFFLGELNPRFSVTATKAKVIEVKEETSDSKTIVLKPNWLWKGFASGQHVPVTVEI
AGRRVTRFYSLSSHPNDKYLQITVKRQKGGLVSNFINQNIKKGDILELGEASGDFVLTKELPKDLLFLAGGSGITPIHSI
LRSLQTLNYTGKATLLYFVRSYDDIIFKSSFDSMQKNSNWLTVHYVFSDIPKEGYASGFLSKEILETYVPNLKSSSVYVC
GPSPMQTKALSLLEGLPVKSELFLLPGQNVGKVKKEGTVDVFLTLSHKTIQVKGERSILEELEEQGIYPQSGCRMGICHT
CVCKKQTGSITDLSNGETSQLGEENIQICVSRAESNLELEL
>Mature_361_residues
MKSFPFIYNEPREFLSSLQPKEWANFFLGELNPRFSVTATKAKVIEVKEETSDSKTIVLKPNWLWKGFASGQHVPVTVEI
AGRRVTRFYSLSSHPNDKYLQITVKRQKGGLVSNFINQNIKKGDILELGEASGDFVLTKELPKDLLFLAGGSGITPIHSI
LRSLQTLNYTGKATLLYFVRSYDDIIFKSSFDSMQKNSNWLTVHYVFSDIPKEGYASGFLSKEILETYVPNLKSSSVYVC
GPSPMQTKALSLLEGLPVKSELFLLPGQNVGKVKKEGTVDVFLTLSHKTIQVKGERSILEELEEQGIYPQSGCRMGICHT
CVCKKQTGSITDLSNGETSQLGEENIQICVSRAESNLELEL

Specific function: This is an electron transfer partner for desA3 [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI84875541, Length=239, Percent_Identity=29.2887029288703, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1787098, Length=326, Percent_Identity=27.9141104294479, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1787658, Length=316, Percent_Identity=27.2151898734177, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1788903, Length=203, Percent_Identity=26.1083743842365, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788104, Length=306, Percent_Identity=25.8169934640523, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323510, Length=186, Percent_Identity=31.1827956989247, Blast_Score=80, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6323552, Length=221, Percent_Identity=28.9592760180996, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322146, Length=189, Percent_Identity=25.9259259259259, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40296; Mature: 40296

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSFPFIYNEPREFLSSLQPKEWANFFLGELNPRFSVTATKAKVIEVKEETSDSKTIVLK
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCEEEEC
PNWLWKGFASGQHVPVTVEIAGRRVTRFYSLSSHPNDKYLQITVKRQKGGLVSNFINQNI
CCCEEECCCCCCEEEEEEEECCCEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHCCC
KKGDILELGEASGDFVLTKELPKDLLFLAGGSGITPIHSILRSLQTLNYTGKATLLYFVR
CCCCCEEECCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEH
SYDDIIFKSSFDSMQKNSNWLTVHYVFSDIPKEGYASGFLSKEILETYVPNLKSSSVYVC
HHCHHEEECCHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
GPSPMQTKALSLLEGLPVKSELFLLPGQNVGKVKKEGTVDVFLTLSHKTIQVKGERSILE
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEEEECHHHHHH
ELEEQGIYPQSGCRMGICHTCVCKKQTGSITDLSNGETSQLGEENIQICVSRAESNLELE
HHHHCCCCCCCCCEECCHHHEEECCCCCCEEECCCCCHHHCCHHHHHEEEEECCCCCEEE
L
C
>Mature Secondary Structure
MKSFPFIYNEPREFLSSLQPKEWANFFLGELNPRFSVTATKAKVIEVKEETSDSKTIVLK
CCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCEEEEEEECCCCCCCEEEEC
PNWLWKGFASGQHVPVTVEIAGRRVTRFYSLSSHPNDKYLQITVKRQKGGLVSNFINQNI
CCCEEECCCCCCEEEEEEEECCCEEEEEEEECCCCCCCEEEEEEEECCCCHHHHHHHCCC
KKGDILELGEASGDFVLTKELPKDLLFLAGGSGITPIHSILRSLQTLNYTGKATLLYFVR
CCCCCEEECCCCCCEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEH
SYDDIIFKSSFDSMQKNSNWLTVHYVFSDIPKEGYASGFLSKEILETYVPNLKSSSVYVC
HHCHHEEECCHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
GPSPMQTKALSLLEGLPVKSELFLLPGQNVGKVKKEGTVDVFLTLSHKTIQVKGERSILE
CCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEECCEEEEEECHHHHHH
ELEEQGIYPQSGCRMGICHTCVCKKQTGSITDLSNGETSQLGEENIQICVSRAESNLELE
HHHHCCCCCCCCCEECCHHHEEECCCCCCEEECCCCCHHHCCHHHHHEEEEECCCCCEEE
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]