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The map label for this gene is manA [H]

Identifier: 183222429

GI number: 183222429

Start: 3192356

End: 3193372

Strand: Direct

Name: manA [H]

Synonym: LEPBI_I3083

Alternate gene names: 183222429

Gene position: 3192356-3193372 (Clockwise)

Preceding gene: 183222428

Following gene: 183222435

Centisome position: 88.68

GC content: 41.4

Gene sequence:

>1017_bases
ATGGAAATCATCCCAAAAGTCTTATTTTTTTCCCCCATTTACAAAGAAAAAATCTGGGGTGGTAGAAAACTGGAATCCCT
ATTGGGGCGAAAGATCCCAGAAGGTATCATTGGAGAATCTTGGGAAGTTTCCGTTTACGACACCGATATCTCACCCGTCC
AAAACCCTGAATTTGATAACCTCCCACTCACAGAACTCATCCAAAAAGCACCTAACGAAGTACTCGGAAAACCATTTGCC
AATTCTAGTTTACCCCTACTTGTCAAAGTCATTGATGCCAAAGAAAAACTTTCGGTCCAAGTGCACCCAGATGATGCCTA
TGCATTGAAGTATGATCCCAAATCAAAAGGCAAAAAGGAATGTTGGTACGTTTTGTCCGCAGATCCAGGGGCAGAGTTAG
TCGTTGGTTTTGGTGTCGAAACCAATCGCGAAGGATACGAATCACTCGTAAAACAAAATTTAGGTGAATCGATTCTAAGG
AAATGGAAAGTAAAATCGGGAGATGTATTCCTTCTGAATCCTGGCACCATCCATGCCATTGGTGGTGGTGTGGTCTTACT
CGAGGTGCAACAATCATCTGATTCCACTTACCGAGTTTATGATTATGGCCGAATTGGTGATGATGGTAAACCAAGAGAAC
TCCATTTAGAAAAAGCGTTATCTGTTTTAAATTTTCAAAAATCAAATGGGGAAGAAAAATTATCAAAACAAGTATTATGT
TACCACCCTTTCCCACGTTATTTGTATACTTCAAATGATAAATTTAGACTTGAGTCTTGGGAATTTGACCAGGCACAAAA
CTTCACCTTTACCCCGTTAGCCGAGCCGTCTTGTTTTGGAATCTTTTTTACTGTATCGGGATCGGTATATTTTCCTGAAC
TGCAGCGGACCGTGGGTCCGAATGAAACATTTTTTATGACAGCTACGGGTTTCCAAGAAACCATCTCCGCTTACGCCGCT
CCTGGCACAAAACTAGCCTTTATGTCGGCAGGGACAGATATGGTCAAATACCAATAA

Upstream 100 bases:

>100_bases
ATTCGTTCACTCATTTTAAGAAAAAATTCCTTCGGGTCAAACTTCTCATTCATAAAAATATCCCTTTACGGACGAAGACT
GCCGTCTAAAAAGGCAATTG

Downstream 100 bases:

>100_bases
ACATATCCATTTGGCAAAGTAAATTAAGGAAAAAAAACTTGGGCAGACTGTCTGATTCGAACTAAGGACAATGGATTCAG
AACGAATCCAATCAAAATTT

Product: mannose-6-phosphate isomerase

Products: NA

Alternate protein names: Phosphohexomutase; Phosphomannose isomerase; PMI [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MEIIPKVLFFSPIYKEKIWGGRKLESLLGRKIPEGIIGESWEVSVYDTDISPVQNPEFDNLPLTELIQKAPNEVLGKPFA
NSSLPLLVKVIDAKEKLSVQVHPDDAYALKYDPKSKGKKECWYVLSADPGAELVVGFGVETNREGYESLVKQNLGESILR
KWKVKSGDVFLLNPGTIHAIGGGVVLLEVQQSSDSTYRVYDYGRIGDDGKPRELHLEKALSVLNFQKSNGEEKLSKQVLC
YHPFPRYLYTSNDKFRLESWEFDQAQNFTFTPLAEPSCFGIFFTVSGSVYFPELQRTVGPNETFFMTATGFQETISAYAA
PGTKLAFMSAGTDMVKYQ

Sequences:

>Translated_338_residues
MEIIPKVLFFSPIYKEKIWGGRKLESLLGRKIPEGIIGESWEVSVYDTDISPVQNPEFDNLPLTELIQKAPNEVLGKPFA
NSSLPLLVKVIDAKEKLSVQVHPDDAYALKYDPKSKGKKECWYVLSADPGAELVVGFGVETNREGYESLVKQNLGESILR
KWKVKSGDVFLLNPGTIHAIGGGVVLLEVQQSSDSTYRVYDYGRIGDDGKPRELHLEKALSVLNFQKSNGEEKLSKQVLC
YHPFPRYLYTSNDKFRLESWEFDQAQNFTFTPLAEPSCFGIFFTVSGSVYFPELQRTVGPNETFFMTATGFQETISAYAA
PGTKLAFMSAGTDMVKYQ
>Mature_338_residues
MEIIPKVLFFSPIYKEKIWGGRKLESLLGRKIPEGIIGESWEVSVYDTDISPVQNPEFDNLPLTELIQKAPNEVLGKPFA
NSSLPLLVKVIDAKEKLSVQVHPDDAYALKYDPKSKGKKECWYVLSADPGAELVVGFGVETNREGYESLVKQNLGESILR
KWKVKSGDVFLLNPGTIHAIGGGVVLLEVQQSSDSTYRVYDYGRIGDDGKPRELHLEKALSVLNFQKSNGEEKLSKQVLC
YHPFPRYLYTSNDKFRLESWEFDQAQNFTFTPLAEPSCFGIFFTVSGSVYFPELQRTVGPNETFFMTATGFQETISAYAA
PGTKLAFMSAGTDMVKYQ

Specific function: Unknown

COG id: COG1482

COG function: function code G; Phosphomannose isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR001250
- InterPro:   IPR014628
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01238 PMI_typeI [H]

EC number: =5.3.1.8 [H]

Molecular weight: Translated: 37901; Mature: 37901

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIIPKVLFFSPIYKEKIWGGRKLESLLGRKIPEGIIGESWEVSVYDTDISPVQNPEFDN
CCCCCHHHHHCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
LPLTELIQKAPNEVLGKPFANSSLPLLVKVIDAKEKLSVQVHPDDAYALKYDPKSKGKKE
CCHHHHHHHCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCE
CWYVLSADPGAELVVGFGVETNREGYESLVKQNLGESILRKWKVKSGDVFLLNPGTIHAI
EEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEE
GGGVVLLEVQQSSDSTYRVYDYGRIGDDGKPRELHLEKALSVLNFQKSNGEEKLSKQVLC
CCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHCCEEE
YHPFPRYLYTSNDKFRLESWEFDQAQNFTFTPLAEPSCFGIFFTVSGSVYFPELQRTVGP
ECCCCCEEEECCCCEEEECCCCCCCCCCEECCCCCCCEEEEEEEECCCEECCHHHHHCCC
NETFFMTATGFQETISAYAAPGTKLAFMSAGTDMVKYQ
CCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCEEEC
>Mature Secondary Structure
MEIIPKVLFFSPIYKEKIWGGRKLESLLGRKIPEGIIGESWEVSVYDTDISPVQNPEFDN
CCCCCHHHHHCHHHHHHHCCCHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCC
LPLTELIQKAPNEVLGKPFANSSLPLLVKVIDAKEKLSVQVHPDDAYALKYDPKSKGKKE
CCHHHHHHHCCHHHHCCCCCCCCCCEEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCE
CWYVLSADPGAELVVGFGVETNREGYESLVKQNLGESILRKWKVKSGDVFLLNPGTIHAI
EEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEE
GGGVVLLEVQQSSDSTYRVYDYGRIGDDGKPRELHLEKALSVLNFQKSNGEEKLSKQVLC
CCCEEEEEEECCCCCEEEEEECCCCCCCCCCCEEEHHHHHHHHHHHCCCCHHHHHCCEEE
YHPFPRYLYTSNDKFRLESWEFDQAQNFTFTPLAEPSCFGIFFTVSGSVYFPELQRTVGP
ECCCCCEEEECCCCEEEECCCCCCCCCCEECCCCCCCEEEEEEEECCCEECCHHHHHCCC
NETFFMTATGFQETISAYAAPGTKLAFMSAGTDMVKYQ
CCEEEEEECCHHHHHHHHCCCCCEEEEEECCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8293960; 12397186 [H]