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The map label for this gene is tdh [H]

Identifier: 183222399

GI number: 183222399

Start: 3165809

End: 3166831

Strand: Direct

Name: tdh [H]

Synonym: LEPBI_I3053

Alternate gene names: 183222399

Gene position: 3165809-3166831 (Clockwise)

Preceding gene: 183222398

Following gene: 183222400

Centisome position: 87.95

GC content: 44.38

Gene sequence:

>1023_bases
ATGTTACAACTTGTGTTTCGCAAAAAAGGAATCTTGGATTGGGAAGAAGTGGAACCACCCACAATCACAGGTGAAAACCA
AGCTCTTGTTGAACCAATTGCTATTGCTCGCTGTGATTTGGATTTACCCATCGTGAGAGGTGAAACATTATTCCGTCCAC
CGTTTCCCGTAGGACACGAGTTTGTTGGTCGTATCAAACAAATCTCTGAAGACTTAGAAGGAAAATTCAAAATTGGTGCG
ATTGTGGCTCTCCCCTTCCAAATCTCATGTGGGACATGTCCAACTTGTTTGTCCCACCATTCCAATTCTTGTGAGACTGT
GCCCTACACGTCTGCTTATGGAATGCCACCAGGTGCCCATCATGTTGGTGGTGCTATCACAGAACTCATCAAAGTTCCAT
TCGCAAAACAAATGTTATTTGAACTGGATCCAAATATCAATCCTGTGGGGATTGCCAGTTTCAGTGACAATATTGCCGAA
GCCTGGAAACTTGCTGGCCGTTTTTTAGAACGCAAAAAAGATCCCAAAACATTAGTGGTGGGAGGAAACGCCGGAAGCAT
TGGACTCTACACGGCACTTTACCTCCACCAAACAAAAAAAGCCGAAGTGGTGTATGCCGACACAGACAAAACACGCATTG
AACTCGCTGCTTCCCTTGGGATCCCCGTGAACCATTACACAACATTTCCCAAACCAAATTCAAAATATGATTTGGTATGT
GATGCCTCTGCCACAAAAGAAGGTTGGGAGTTTGCTACAAGGTCTTTGGGACGAAATGCAATTCTAAGTTCTGCCTCCAT
CTTTTGGACCAATCGATTGGAAATTCCCTATTTGGAGATGTACAACCAAGGTGCAGAAATTCAGATTGGCCGAGTGGAAT
CCATTGATTCGATGCATGCCTTGTATCCAGAGATCCAAAGTGGAGTGTTTACCCCAGAAAAAATCGTGACGAAAACGGTT
TCCTTTGCCGAAGCCAAAGAAGCTTGGATGGAAGAGTCGATCAAACTCGTGGTCACTCGTTAA

Upstream 100 bases:

>100_bases
GAAAATCAAATGCCCCATCTCCCAGAATGGTTCCGTAAATTTTAGTTGATGGGAAAATCCAAGGTTCAATAAGTAGACCG
AACGGTATACAGAGGATCAA

Downstream 100 bases:

>100_bases
ACATTGGATTGGAATCAATTTTGAGAAAACATTTCGATAGAAATCGCGAAACTAAACTTTCTTCTAAGAGGAAATGGAAT
CTCCTTTTCCATTGTGGAAT

Product: putative L-threonine 3-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MLQLVFRKKGILDWEEVEPPTITGENQALVEPIAIARCDLDLPIVRGETLFRPPFPVGHEFVGRIKQISEDLEGKFKIGA
IVALPFQISCGTCPTCLSHHSNSCETVPYTSAYGMPPGAHHVGGAITELIKVPFAKQMLFELDPNINPVGIASFSDNIAE
AWKLAGRFLERKKDPKTLVVGGNAGSIGLYTALYLHQTKKAEVVYADTDKTRIELAASLGIPVNHYTTFPKPNSKYDLVC
DASATKEGWEFATRSLGRNAILSSASIFWTNRLEIPYLEMYNQGAEIQIGRVESIDSMHALYPEIQSGVFTPEKIVTKTV
SFAEAKEAWMEESIKLVVTR

Sequences:

>Translated_340_residues
MLQLVFRKKGILDWEEVEPPTITGENQALVEPIAIARCDLDLPIVRGETLFRPPFPVGHEFVGRIKQISEDLEGKFKIGA
IVALPFQISCGTCPTCLSHHSNSCETVPYTSAYGMPPGAHHVGGAITELIKVPFAKQMLFELDPNINPVGIASFSDNIAE
AWKLAGRFLERKKDPKTLVVGGNAGSIGLYTALYLHQTKKAEVVYADTDKTRIELAASLGIPVNHYTTFPKPNSKYDLVC
DASATKEGWEFATRSLGRNAILSSASIFWTNRLEIPYLEMYNQGAEIQIGRVESIDSMHALYPEIQSGVFTPEKIVTKTV
SFAEAKEAWMEESIKLVVTR
>Mature_340_residues
MLQLVFRKKGILDWEEVEPPTITGENQALVEPIAIARCDLDLPIVRGETLFRPPFPVGHEFVGRIKQISEDLEGKFKIGA
IVALPFQISCGTCPTCLSHHSNSCETVPYTSAYGMPPGAHHVGGAITELIKVPFAKQMLFELDPNINPVGIASFSDNIAE
AWKLAGRFLERKKDPKTLVVGGNAGSIGLYTALYLHQTKKAEVVYADTDKTRIELAASLGIPVNHYTTFPKPNSKYDLVC
DASATKEGWEFATRSLGRNAILSSASIFWTNRLEIPYLEMYNQGAEIQIGRVESIDSMHALYPEIQSGVFTPEKIVTKTV
SFAEAKEAWMEESIKLVVTR

Specific function: Unknown

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI226510992, Length=229, Percent_Identity=30.1310043668122, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR004627
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.103 [H]

Molecular weight: Translated: 37543; Mature: 37543

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQLVFRKKGILDWEEVEPPTITGENQALVEPIAIARCDLDLPIVRGETLFRPPFPVGHE
CEEEEEECCCCCCHHHCCCCEECCCCCHHHCHHEEEEECCCCEEECCCCEECCCCCCCHH
FVGRIKQISEDLEGKFKIGAIVALPFQISCGTCPTCLSHHSNSCETVPYTSAYGMPPGAH
HHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCH
HVGGAITELIKVPFAKQMLFELDPNINPVGIASFSDNIAEAWKLAGRFLERKKDPKTLVV
HHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEE
GGNAGSIGLYTALYLHQTKKAEVVYADTDKTRIELAASLGIPVNHYTTFPKPNSKYDLVC
ECCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
DASATKEGWEFATRSLGRNAILSSASIFWTNRLEIPYLEMYNQGAEIQIGRVESIDSMHA
CCCCCCHHHHHHHHHCCCHHHHCCCEEEEECCCCCCHHHHHCCCCEEEECCHHCHHHHHH
LYPEIQSGVFTPEKIVTKTVSFAEAKEAWMEESIKLVVTR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEC
>Mature Secondary Structure
MLQLVFRKKGILDWEEVEPPTITGENQALVEPIAIARCDLDLPIVRGETLFRPPFPVGHE
CEEEEEECCCCCCHHHCCCCEECCCCCHHHCHHEEEEECCCCEEECCCCEECCCCCCCHH
FVGRIKQISEDLEGKFKIGAIVALPFQISCGTCPTCLSHHSNSCETVPYTSAYGMPPGAH
HHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCCCCCH
HVGGAITELIKVPFAKQMLFELDPNINPVGIASFSDNIAEAWKLAGRFLERKKDPKTLVV
HHHHHHHHHHHCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEE
GGNAGSIGLYTALYLHQTKKAEVVYADTDKTRIELAASLGIPVNHYTTFPKPNSKYDLVC
ECCCCCHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEE
DASATKEGWEFATRSLGRNAILSSASIFWTNRLEIPYLEMYNQGAEIQIGRVESIDSMHA
CCCCCCHHHHHHHHHCCCHHHHCCCEEEEECCCCCCHHHHHCCCCEEEECCHHCHHHHHH
LYPEIQSGVFTPEKIVTKTVSFAEAKEAWMEESIKLVVTR
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA