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The map label for this gene is sasA [H]

Identifier: 183222148

GI number: 183222148

Start: 2888278

End: 2890308

Strand: Direct

Name: sasA [H]

Synonym: LEPBI_I2791

Alternate gene names: 183222148

Gene position: 2888278-2890308 (Clockwise)

Preceding gene: 183222147

Following gene: 183222149

Centisome position: 80.24

GC content: 33.53

Gene sequence:

>2031_bases
ATGGATTTGAAACGTTGGGTTTTTATCTTTTCTCTTCTCAGTTTTTACACTAGTGGAAGCCTTCATGCGGAAAATTTACC
GATTTCAAAACAAGGAGTCATCGATCTATCTCAAGTCAATTTTATAGAACAAACGTCAATTCCTTTGGCGGGAGATTGGG
AATTTCAATGGAACGAGTTCACCTCTCCCCTATCAAACGATACAGACGCGTTCACCTTTAACCAAATTCAAAAAGCAAAA
CAAAATCATTCTACGAACTACCTAGCGACTGGGAAACGATGGAAAGAAATACACTCTGGCGTTGGATTTGCTACTTACCA
ATTAAGAATTATTTTCCCAGAAGGATCGAACCAGCAAATTTTTAGTATACGTTTTTTCCAAACAGGCGGTGCCGCTATGC
GCGTGTTTGTCGACGGGAAGGAATCTCTTTCACTAGGTAAAGTTGGTACAGACAAACTAACCATGGAACCAACCAGGCGT
TCTGGAATTTTAATCCTTCCTCATCCAAAAAAAGTTACAAACATACTAGTACATATTTCAAATTTTCATCATGATGATGG
CTCATTTTGGTATGCACCAAAGATTGGACTTTACCAAGATATACAAAACAATCTTATCAAAGAAATCGCATTAGATTCGC
TGTTATCTGGCGCTTTATTCTTTATGGCATTTTATCACTTTGTTTTATTCTTTTTCAGGAGAACTAGAAAATTAATTTTA
TATTTTGGATTATTTTGCCTCACAACTGCTTTTCATTCACTTTCTTTGAATGGCGATGTCCTATATTATATTTATCACGC
GATTCCTTATCATTTTGCTTTTGCTCTATCGCTCATTTTTTATTTAGCAATGCCATTTTATCTTTATTTTTTATTCCAAT
TTTTTCCAAATCAGTTTTCAAAAAGAGTTATTAATATTTATTCTACAATCTCTTTTGTTTTGTTTTCTTTTGTTCTTTTG
ACTCCTACAGAGATAGGATCGAAAACAACTTTCATCGGGCTTGTTTTCACAAATTCGGGTTTACTCTATTCGACAATTTG
TCTAACAAGAAGTGCGATCAAAAAGCAACAACTTGCTGTAAGTTTATTATTAATCCAATTGTTTTTACTATTAAGTGCGA
TTAACGATACCTTATATTTATATGGAATCTTTCATCAAACTCTTATTTTAAAATATTCATATTTAACTACTGTATTGTTC
CAATCACTACTTCTTGCCTCATACTTTACTAAAATGTTCATTAAAAATGAAACTTTGAAAAATGAACTCGCAACATTAAA
CGAATCATTAGAAAAAACCATTATAGTGAGAACAAAAGAATACAAAGAAGCCAAACAAATTGCGGAGGATGCGAATCAAT
GGAAAGATAAGTTTATATCACTTGTAGCACATGACTTACGATCTCCACTTAGCACTGTGTATTCGGCACTCACTCTAACC
ACCGACAAAGAAACAACTGAAGACGACAAAACACATATTCTAAATCAAGTATTTGCGATTTTAGAAAATGCAATGTCAAC
GATTGAACATTTATTAAATTTAAATCGGTTCCAAATAGACAAAGGACAAATACACTTACAGATCACACAAATCACTGTGA
ACGACCACTTAAAACAAGTTGTTGATACTTTCACTTTTGAAATTCAAAAAAAATCTTTGTCCATCGTGAATTTGATAGCT
GATTCGGCCAAAGTGTTTGCAGATTCTTCGATTTTTCTTGAGATACTTCGAAATTTAATAGCAAATGCGATCAAATTTAG
CCACCCAAAAGGTAAAATCCAAATGGACTTTTTAGAAACTAACGACAGTTTTATAATTTCAATTAAGGACGAAGGTACTG
GAATTCCGATCGAACGCCAAAAGGATTTATTCATTGAGCCAATGTCTTCACCTGGAACTTTAGGTGAAAAAGGTTTTGGG
ATAGGACTGAAACTTTGTTTTGAATTAATGAGATTACATCATGGAAATATCCAAGTGGAATCGGAATCCAATTCAGGAAG
TCGATTCCTTTTGATATTTCCGAAGAAATGA

Upstream 100 bases:

>100_bases
AAGGGACTTGTACAACTTCCGTAAGGATCGATCAAATATTCCTTTGAATCTAAGAGAGGAAATCTAAAGTTGGTTCAGGA
TATTTGTCTTCTGGACCAAA

Downstream 100 bases:

>100_bases
ACTACTAATCAATCTAGAGACACTTAATTTTCGTTAGCTTTTATTTTCAGCAATATGAATGATTCATATTCATTAAATAC
CAAAAGTAACAAATCTCAGA

Product: putative signal peptide

Products: NA

Alternate protein names: Synechococcus adaptive sensor protein A [H]

Number of amino acids: Translated: 676; Mature: 676

Protein sequence:

>676_residues
MDLKRWVFIFSLLSFYTSGSLHAENLPISKQGVIDLSQVNFIEQTSIPLAGDWEFQWNEFTSPLSNDTDAFTFNQIQKAK
QNHSTNYLATGKRWKEIHSGVGFATYQLRIIFPEGSNQQIFSIRFFQTGGAAMRVFVDGKESLSLGKVGTDKLTMEPTRR
SGILILPHPKKVTNILVHISNFHHDDGSFWYAPKIGLYQDIQNNLIKEIALDSLLSGALFFMAFYHFVLFFFRRTRKLIL
YFGLFCLTTAFHSLSLNGDVLYYIYHAIPYHFAFALSLIFYLAMPFYLYFLFQFFPNQFSKRVINIYSTISFVLFSFVLL
TPTEIGSKTTFIGLVFTNSGLLYSTICLTRSAIKKQQLAVSLLLIQLFLLLSAINDTLYLYGIFHQTLILKYSYLTTVLF
QSLLLASYFTKMFIKNETLKNELATLNESLEKTIIVRTKEYKEAKQIAEDANQWKDKFISLVAHDLRSPLSTVYSALTLT
TDKETTEDDKTHILNQVFAILENAMSTIEHLLNLNRFQIDKGQIHLQITQITVNDHLKQVVDTFTFEIQKKSLSIVNLIA
DSAKVFADSSIFLEILRNLIANAIKFSHPKGKIQMDFLETNDSFIISIKDEGTGIPIERQKDLFIEPMSSPGTLGEKGFG
IGLKLCFELMRLHHGNIQVESESNSGSRFLLIFPKK

Sequences:

>Translated_676_residues
MDLKRWVFIFSLLSFYTSGSLHAENLPISKQGVIDLSQVNFIEQTSIPLAGDWEFQWNEFTSPLSNDTDAFTFNQIQKAK
QNHSTNYLATGKRWKEIHSGVGFATYQLRIIFPEGSNQQIFSIRFFQTGGAAMRVFVDGKESLSLGKVGTDKLTMEPTRR
SGILILPHPKKVTNILVHISNFHHDDGSFWYAPKIGLYQDIQNNLIKEIALDSLLSGALFFMAFYHFVLFFFRRTRKLIL
YFGLFCLTTAFHSLSLNGDVLYYIYHAIPYHFAFALSLIFYLAMPFYLYFLFQFFPNQFSKRVINIYSTISFVLFSFVLL
TPTEIGSKTTFIGLVFTNSGLLYSTICLTRSAIKKQQLAVSLLLIQLFLLLSAINDTLYLYGIFHQTLILKYSYLTTVLF
QSLLLASYFTKMFIKNETLKNELATLNESLEKTIIVRTKEYKEAKQIAEDANQWKDKFISLVAHDLRSPLSTVYSALTLT
TDKETTEDDKTHILNQVFAILENAMSTIEHLLNLNRFQIDKGQIHLQITQITVNDHLKQVVDTFTFEIQKKSLSIVNLIA
DSAKVFADSSIFLEILRNLIANAIKFSHPKGKIQMDFLETNDSFIISIKDEGTGIPIERQKDLFIEPMSSPGTLGEKGFG
IGLKLCFELMRLHHGNIQVESESNSGSRFLLIFPKK
>Mature_676_residues
MDLKRWVFIFSLLSFYTSGSLHAENLPISKQGVIDLSQVNFIEQTSIPLAGDWEFQWNEFTSPLSNDTDAFTFNQIQKAK
QNHSTNYLATGKRWKEIHSGVGFATYQLRIIFPEGSNQQIFSIRFFQTGGAAMRVFVDGKESLSLGKVGTDKLTMEPTRR
SGILILPHPKKVTNILVHISNFHHDDGSFWYAPKIGLYQDIQNNLIKEIALDSLLSGALFFMAFYHFVLFFFRRTRKLIL
YFGLFCLTTAFHSLSLNGDVLYYIYHAIPYHFAFALSLIFYLAMPFYLYFLFQFFPNQFSKRVINIYSTISFVLFSFVLL
TPTEIGSKTTFIGLVFTNSGLLYSTICLTRSAIKKQQLAVSLLLIQLFLLLSAINDTLYLYGIFHQTLILKYSYLTTVLF
QSLLLASYFTKMFIKNETLKNELATLNESLEKTIIVRTKEYKEAKQIAEDANQWKDKFISLVAHDLRSPLSTVYSALTLT
TDKETTEDDKTHILNQVFAILENAMSTIEHLLNLNRFQIDKGQIHLQITQITVNDHLKQVVDTFTFEIQKKSLSIVNLIA
DSAKVFADSSIFLEILRNLIANAIKFSHPKGKIQMDFLETNDSFIISIKDEGTGIPIERQKDLFIEPMSSPGTLGEKGFG
IGLKLCFELMRLHHGNIQVESESNSGSRFLLIFPKK

Specific function: May be involved in signal transduction. Participates in the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with kaiC. Required for robustness of the circadian rhythm of gene expression an

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=27.9166666666667, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788713, Length=227, Percent_Identity=23.7885462555066, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1789149, Length=277, Percent_Identity=26.7148014440433, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788549, Length=220, Percent_Identity=27.2727272727273, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786912, Length=311, Percent_Identity=22.508038585209, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790436, Length=248, Percent_Identity=27.8225806451613, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=241, Percent_Identity=26.9709543568465, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081816, Length=267, Percent_Identity=22.0973782771536, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790551, Length=227, Percent_Identity=27.7533039647577, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI48994928, Length=245, Percent_Identity=27.3469387755102, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=227, Percent_Identity=23.7885462555066, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788393, Length=224, Percent_Identity=20.0892857142857, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011649
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF07689 KaiB [H]

EC number: 2.7.3.- [C]

Molecular weight: Translated: 77322; Mature: 77322

Theoretical pI: Translated: 8.79; Mature: 8.79

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLKRWVFIFSLLSFYTSGSLHAENLPISKQGVIDLSQVNFIEQTSIPLAGDWEFQWNEF
CCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEHHHCCHHHHCCCCCCCCCCCCCHHH
TSPLSNDTDAFTFNQIQKAKQNHSTNYLATGKRWKEIHSGVGFATYQLRIIFPEGSNQQI
CCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCEEEEEEEEEEECCCCCEE
FSIRFFQTGGAAMRVFVDGKESLSLGKVGTDKLTMEPTRRSGILILPHPKKVTNILVHIS
EEEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEECCCHHHHHHHEEEE
NFHHDDGSFWYAPKIGLYQDIQNNLIKEIALDSLLSGALFFMAFYHFVLFFFRRTRKLIL
CEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFGLFCLTTAFHSLSLNGDVLYYIYHAIPYHFAFALSLIFYLAMPFYLYFLFQFFPNQFS
HHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRVINIYSTISFVLFSFVLLTPTEIGSKTTFIGLVFTNSGLLYSTICLTRSAIKKQQLAV
HHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
SLLLIQLFLLLSAINDTLYLYGIFHQTLILKYSYLTTVLFQSLLLASYFTKMFIKNETLK
HHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NELATLNESLEKTIIVRTKEYKEAKQIAEDANQWKDKFISLVAHDLRSPLSTVYSALTLT
HHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TDKETTEDDKTHILNQVFAILENAMSTIEHLLNLNRFQIDKGQIHLQITQITVNDHLKQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEEEEHHHHHHHH
VDTFTFEIQKKSLSIVNLIADSAKVFADSSIFLEILRNLIANAIKFSHPKGKIQMDFLET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
NDSFIISIKDEGTGIPIERQKDLFIEPMSSPGTLGEKGFGIGLKLCFELMRLHHGNIQVE
CCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
SESNSGSRFLLIFPKK
ECCCCCCEEEEEECCC
>Mature Secondary Structure
MDLKRWVFIFSLLSFYTSGSLHAENLPISKQGVIDLSQVNFIEQTSIPLAGDWEFQWNEF
CCHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCEEHHHCCHHHHCCCCCCCCCCCCCHHH
TSPLSNDTDAFTFNQIQKAKQNHSTNYLATGKRWKEIHSGVGFATYQLRIIFPEGSNQQI
CCCCCCCCCCHHHHHHHHHHHCCCCCEEECCHHHHHHHCCCCEEEEEEEEEEECCCCCEE
FSIRFFQTGGAAMRVFVDGKESLSLGKVGTDKLTMEPTRRSGILILPHPKKVTNILVHIS
EEEEEEECCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEECCCHHHHHHHEEEE
NFHHDDGSFWYAPKIGLYQDIQNNLIKEIALDSLLSGALFFMAFYHFVLFFFRRTRKLIL
CEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YFGLFCLTTAFHSLSLNGDVLYYIYHAIPYHFAFALSLIFYLAMPFYLYFLFQFFPNQFS
HHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRVINIYSTISFVLFSFVLLTPTEIGSKTTFIGLVFTNSGLLYSTICLTRSAIKKQQLAV
HHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHH
SLLLIQLFLLLSAINDTLYLYGIFHQTLILKYSYLTTVLFQSLLLASYFTKMFIKNETLK
HHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
NELATLNESLEKTIIVRTKEYKEAKQIAEDANQWKDKFISLVAHDLRSPLSTVYSALTLT
HHHHHHHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEE
TDKETTEDDKTHILNQVFAILENAMSTIEHLLNLNRFQIDKGQIHLQITQITVNDHLKQV
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEEEEEEEEHHHHHHHH
VDTFTFEIQKKSLSIVNLIADSAKVFADSSIFLEILRNLIANAIKFSHPKGKIQMDFLET
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
NDSFIISIKDEGTGIPIERQKDLFIEPMSSPGTLGEKGFGIGLKLCFELMRLHHGNIQVE
CCCEEEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEE
SESNSGSRFLLIFPKK
ECCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Phosphotransferases with a nitrogenous group as acceptor [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA