| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is rsbU [H]
Identifier: 183222048
GI number: 183222048
Start: 2786874
End: 2788958
Strand: Reverse
Name: rsbU [H]
Synonym: LEPBI_I2690
Alternate gene names: 183222048
Gene position: 2788958-2786874 (Counterclockwise)
Preceding gene: 183222049
Following gene: 183222043
Centisome position: 77.48
GC content: 36.16
Gene sequence:
>2085_bases GTGAAACATTATCTCCGTTGGATCACATTCCTTTGGAGTTTGGTACTTTTGACATGTTCAGTGGCAGAAGTACCGCCAGT TGCGGAGAAAGGGCACTTAACTGCCGTTTCATATTTAGCTCAAAACAACCAAATCATTCCTATTGTTGGTGATTGGGAAT ATTACCCAGGGATGTTGTTTTCGCCCTCAGAACTAACTGAAATCAAATCCATACGTGAGCCTCTCTATTTTACAGTTCCA GGCGTTTGGACAAAGTCATTTTTAGAAAAAGGATTTTTGGCAGGTGATGGTTATGGGACCTTTCATGTAGAATTATTACA TGGATTAAAAGGGATTCCACTTTCGATCAAAGTTCCAGAAATGGAATCCGCCTATATATTGTTCGTTGATGGAGAGAGAC TTGCATCCAATGGATATGTTTCCACTTCCTATCAATCAGGGATCCCCGAATACAGACCACAGATCATTGATTTTATACCG AAAGAAAACCAAACTTCATTTTTATTACAAATTTCCAACTACCATCATAGAAAAGGTGGTCCAGCACAGGTCATCATCTT AGGTAGAACCTCCGATATCCATAAACAATACGAATTTCAAATCTTAAGAGATATGTTACTCGTGGGTAGTATCTTATTTA TGGGATTGTATCATATCTTTCTTTATTGGAATCGAAAAAAAGATCCATTTACATATTGGTTTGCTCTCACCTGTATTCTT GTCGCCTTACGAGTGTTTATCACTGGTAACAAATATTTAGTGCAAGTAATTCCTGACCTACCTTGGGAAATCCACCTAAA ACTAAGTTATCTCAGCTTTTTCTTTATCACTCCAATATTTGCAAAATATGTGTATTTATTATTCAAACCATATTTTTCAA GAAGGGTATATGAATTACTTAAGTATGTAGGATATGCTTTTTGTTGCATCGTATTGCTGACGAGATCATCGTTTTATACG TATTTGATGGTGCCATTTCAAATTTTCACCTTACTTGGTGCCATTTATACACTACTTGTTTTATCAAGAGCCATCCGAGA TTCACAACCGGGTTCGCTTATTTTTCTCATTAGTTTTATTGTATTTGTGGCTAGTTTTGTGAATGATATTTTGGTAAACA ATCTCATCATCAATTCACCTCTCACAATTCATTTTGGCATTTTTATGATGTTTTTTGTTCAGTCAATATACATCGCCCGC AATTTTTCAAAAGGATTTGTGGATGCGGAAAATCTCGCAATAGAACTATCCGAAAAAAACCAAACCCTTCAAAAAGTCCA AAATCAAATTACGATTTTAAATGAACGACTCGAAACTAGGGTCAAAGAAAAAACCATCGAATTACAAAGCAAATTGGATC AAATCACCAAGGATATGAAACTTGCCAAATCTATCATCCAAAGTGTAACCAAAGTACCCGAAATGGAACCACATTTGCGT GTGGATATTTTGTACAAACCAACTGCAGATGTGGGTGGTGATATCTTTTTTGTGAAAAGAATCCAAGATTTTTATTATCG GTTTTTTTTGGGAGATGCTACTGGACACGGATTACAAGCCGCTTTGTATTCCATGATGATCCAATCGGAATTTGAAAGAG TGTCCGCTGTGGCAATGCGACCCAATGATCTTTTGTTTTATATGAACCAACATTTTTATGATAAAAATGCTGATTTACAA ATTTATTTTCCAGCTCTTGTGATGGATTTTGATTTTCACCAAAATATCCTTCGTTATGCGGGAGGTGGTGTTCAAAATCA AATCATTCTGAAAAAAAATAACGAATCACTCATTGTAGAAAATACAGGCCCAATCATTGGTATTTTGGAACATTATCGTT ATGGAATCTTTGAATCCAAAGTGGAATCGGGAGACCGGATTTTTCTTTTTACAGACGGACTCTTTGAAGAATTGAATGAG GCAGATGGGATGCAGGCTTGGGATGACCTTATGCAGACAATCCAAAGTACAAATGAGTTACCGTTCCAAGAAATCATTCC ATCCATCCAAACCATGCTTTTCCAGAAAATGAATAAAACCACATGGAAGGATGATTCCACTTTGATCGTGATTGAAATCA CATAA
Upstream 100 bases:
>100_bases GGGGATTTCTCAAAAGTTCGTCCAAAACAAATTTATGTGGGCGAAAACCAAAGAAAGTACATTCCTATCGCCAACCGTCT CTAGAGGATACGAAGGAATC
Downstream 100 bases:
>100_bases TTAAAAAGAAAGTTTTGCTACCATTCCTATCCTATTTGCGACGGGAATGGTATGGTATCGCAGATGTTCACATAAATTGG CCTAATTGAAATAAAGATTA
Product: putative phosphoserine phosphatase
Products: NA
Alternate protein names: Sigma factor sigB regulation protein rsbU [H]
Number of amino acids: Translated: 694; Mature: 694
Protein sequence:
>694_residues MKHYLRWITFLWSLVLLTCSVAEVPPVAEKGHLTAVSYLAQNNQIIPIVGDWEYYPGMLFSPSELTEIKSIREPLYFTVP GVWTKSFLEKGFLAGDGYGTFHVELLHGLKGIPLSIKVPEMESAYILFVDGERLASNGYVSTSYQSGIPEYRPQIIDFIP KENQTSFLLQISNYHHRKGGPAQVIILGRTSDIHKQYEFQILRDMLLVGSILFMGLYHIFLYWNRKKDPFTYWFALTCIL VALRVFITGNKYLVQVIPDLPWEIHLKLSYLSFFFITPIFAKYVYLLFKPYFSRRVYELLKYVGYAFCCIVLLTRSSFYT YLMVPFQIFTLLGAIYTLLVLSRAIRDSQPGSLIFLISFIVFVASFVNDILVNNLIINSPLTIHFGIFMMFFVQSIYIAR NFSKGFVDAENLAIELSEKNQTLQKVQNQITILNERLETRVKEKTIELQSKLDQITKDMKLAKSIIQSVTKVPEMEPHLR VDILYKPTADVGGDIFFVKRIQDFYYRFFLGDATGHGLQAALYSMMIQSEFERVSAVAMRPNDLLFYMNQHFYDKNADLQ IYFPALVMDFDFHQNILRYAGGGVQNQIILKKNNESLIVENTGPIIGILEHYRYGIFESKVESGDRIFLFTDGLFEELNE ADGMQAWDDLMQTIQSTNELPFQEIIPSIQTMLFQKMNKTTWKDDSTLIVIEIT
Sequences:
>Translated_694_residues MKHYLRWITFLWSLVLLTCSVAEVPPVAEKGHLTAVSYLAQNNQIIPIVGDWEYYPGMLFSPSELTEIKSIREPLYFTVP GVWTKSFLEKGFLAGDGYGTFHVELLHGLKGIPLSIKVPEMESAYILFVDGERLASNGYVSTSYQSGIPEYRPQIIDFIP KENQTSFLLQISNYHHRKGGPAQVIILGRTSDIHKQYEFQILRDMLLVGSILFMGLYHIFLYWNRKKDPFTYWFALTCIL VALRVFITGNKYLVQVIPDLPWEIHLKLSYLSFFFITPIFAKYVYLLFKPYFSRRVYELLKYVGYAFCCIVLLTRSSFYT YLMVPFQIFTLLGAIYTLLVLSRAIRDSQPGSLIFLISFIVFVASFVNDILVNNLIINSPLTIHFGIFMMFFVQSIYIAR NFSKGFVDAENLAIELSEKNQTLQKVQNQITILNERLETRVKEKTIELQSKLDQITKDMKLAKSIIQSVTKVPEMEPHLR VDILYKPTADVGGDIFFVKRIQDFYYRFFLGDATGHGLQAALYSMMIQSEFERVSAVAMRPNDLLFYMNQHFYDKNADLQ IYFPALVMDFDFHQNILRYAGGGVQNQIILKKNNESLIVENTGPIIGILEHYRYGIFESKVESGDRIFLFTDGLFEELNE ADGMQAWDDLMQTIQSTNELPFQEIIPSIQTMLFQKMNKTTWKDDSTLIVIEIT >Mature_694_residues MKHYLRWITFLWSLVLLTCSVAEVPPVAEKGHLTAVSYLAQNNQIIPIVGDWEYYPGMLFSPSELTEIKSIREPLYFTVP GVWTKSFLEKGFLAGDGYGTFHVELLHGLKGIPLSIKVPEMESAYILFVDGERLASNGYVSTSYQSGIPEYRPQIIDFIP KENQTSFLLQISNYHHRKGGPAQVIILGRTSDIHKQYEFQILRDMLLVGSILFMGLYHIFLYWNRKKDPFTYWFALTCIL VALRVFITGNKYLVQVIPDLPWEIHLKLSYLSFFFITPIFAKYVYLLFKPYFSRRVYELLKYVGYAFCCIVLLTRSSFYT YLMVPFQIFTLLGAIYTLLVLSRAIRDSQPGSLIFLISFIVFVASFVNDILVNNLIINSPLTIHFGIFMMFFVQSIYIAR NFSKGFVDAENLAIELSEKNQTLQKVQNQITILNERLETRVKEKTIELQSKLDQITKDMKLAKSIIQSVTKVPEMEPHLR VDILYKPTADVGGDIFFVKRIQDFYYRFFLGDATGHGLQAALYSMMIQSEFERVSAVAMRPNDLLFYMNQHFYDKNADLQ IYFPALVMDFDFHQNILRYAGGGVQNQIILKKNNESLIVENTGPIIGILEHYRYGIFESKVESGDRIFLFTDGLFEELNE ADGMQAWDDLMQTIQSTNELPFQEIIPSIQTMLFQKMNKTTWKDDSTLIVIEIT
Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]
COG id: COG2208
COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Contains 1 PP2C-like domain [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR017944 - InterPro: IPR001932 - InterPro: IPR014787 - InterPro: IPR010822 - ProDom: PD685490 [H]
Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]
EC number: =3.1.3.3 [H]
Molecular weight: Translated: 80274; Mature: 80274
Theoretical pI: Translated: 6.57; Mature: 6.57
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.6 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.6 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKHYLRWITFLWSLVLLTCSVAEVPPVAEKGHLTAVSYLAQNNQIIPIVGDWEYYPGMLF CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEE SPSELTEIKSIREPLYFTVPGVWTKSFLEKGFLAGDGYGTFHVELLHGLKGIPLSIKVPE CCHHHHHHHHHHCCCEEECCCHHHHHHHHCCCEECCCCCEEHHHHHHCCCCCCEEEECCC MESAYILFVDGERLASNGYVSTSYQSGIPEYRPQIIDFIPKENQTSFLLQISNYHHRKGG CCCEEEEEEECCCCCCCCEEECCHHCCCCHHCCHHHHHCCCCCCCEEEEEECCCCCCCCC PAQVIILGRTSDIHKQYEFQILRDMLLVGSILFMGLYHIFLYWNRKKDPFTYWFALTCIL CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH VALRVFITGNKYLVQVIPDLPWEIHLKLSYLSFFFITPIFAKYVYLLFKPYFSRRVYELL HHHHHHHCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KYVGYAFCCIVLLTRSSFYTYLMVPFQIFTLLGAIYTLLVLSRAIRDSQPGSLIFLISFI HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH VFVASFVNDILVNNLIINSPLTIHFGIFMMFFVQSIYIARNFSKGFVDAENLAIELSEKN HHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHH QTLQKVQNQITILNERLETRVKEKTIELQSKLDQITKDMKLAKSIIQSVTKVPEMEPHLR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE VDILYKPTADVGGDIFFVKRIQDFYYRFFLGDATGHGLQAALYSMMIQSEFERVSAVAMR EEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEC PNDLLFYMNQHFYDKNADLQIYFPALVMDFDFHQNILRYAGGGVQNQIILKKNNESLIVE CCCEEEEEEHHCCCCCCCEEEEEHHHEEECHHHHHHHHHCCCCCCCEEEEEECCCEEEEE NTGPIIGILEHYRYGIFESKVESGDRIFLFTDGLFEELNEADGMQAWDDLMQTIQSTNEL CCCCEEHHHHHHHHCHHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCC PFQEIIPSIQTMLFQKMNKTTWKDDSTLIVIEIT CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC >Mature Secondary Structure MKHYLRWITFLWSLVLLTCSVAEVPPVAEKGHLTAVSYLAQNNQIIPIVGDWEYYPGMLF CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCCCEE SPSELTEIKSIREPLYFTVPGVWTKSFLEKGFLAGDGYGTFHVELLHGLKGIPLSIKVPE CCHHHHHHHHHHCCCEEECCCHHHHHHHHCCCEECCCCCEEHHHHHHCCCCCCEEEECCC MESAYILFVDGERLASNGYVSTSYQSGIPEYRPQIIDFIPKENQTSFLLQISNYHHRKGG CCCEEEEEEECCCCCCCCEEECCHHCCCCHHCCHHHHHCCCCCCCEEEEEECCCCCCCCC PAQVIILGRTSDIHKQYEFQILRDMLLVGSILFMGLYHIFLYWNRKKDPFTYWFALTCIL CEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH VALRVFITGNKYLVQVIPDLPWEIHLKLSYLSFFFITPIFAKYVYLLFKPYFSRRVYELL HHHHHHHCCCEEEEEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KYVGYAFCCIVLLTRSSFYTYLMVPFQIFTLLGAIYTLLVLSRAIRDSQPGSLIFLISFI HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH VFVASFVNDILVNNLIINSPLTIHFGIFMMFFVQSIYIARNFSKGFVDAENLAIELSEKN HHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCHH QTLQKVQNQITILNERLETRVKEKTIELQSKLDQITKDMKLAKSIIQSVTKVPEMEPHLR HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE VDILYKPTADVGGDIFFVKRIQDFYYRFFLGDATGHGLQAALYSMMIQSEFERVSAVAMR EEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEC PNDLLFYMNQHFYDKNADLQIYFPALVMDFDFHQNILRYAGGGVQNQIILKKNNESLIVE CCCEEEEEEHHCCCCCCCEEEEEHHHEEECHHHHHHHHHCCCCCCCEEEEEECCCEEEEE NTGPIIGILEHYRYGIFESKVESGDRIFLFTDGLFEELNEADGMQAWDDLMQTIQSTNEL CCCCEEHHHHHHHHCHHHHHHCCCCEEEEEECHHHHHHHHCCCHHHHHHHHHHHHCCCCC PFQEIIPSIQTMLFQKMNKTTWKDDSTLIVIEIT CHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]