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The map label for this gene is tsf

Identifier: 183221975

GI number: 183221975

Start: 2706473

End: 2707069

Strand: Reverse

Name: tsf

Synonym: LEPBI_I2616

Alternate gene names: 183221975

Gene position: 2707069-2706473 (Counterclockwise)

Preceding gene: 183221976

Following gene: 183221974

Centisome position: 75.2

GC content: 43.72

Gene sequence:

>597_bases
ATGGCTGTTAGCTCCGAACAAATCAAAGATCTCCGCGAACGTACGGGCGCGGGAATGATGGACTGCAAAAAAGCCCTCGA
AGAAAAGGGTGGCGATATTGAAAAAGCAGTTACCTATTTAAGAGAAAAAGGTTTAGCGAAAGCGGCAAAACGAGCTGGTC
GCGAAACTGGCGAAGGGAAAGTGATCGCTTATGTTCACGGAACAGGGAAAACAGGAGTTCTAGTGGAACTTAACTGTGAA
ACTGATTTCGTTGCAAACAACGAAGCGTTTGAAGCCCTTGGCAAAGAGATTGCATTGCAAATCACTGCGATGAGCCCACT
GTATGTGAGCGAAGAATCCATTCCCAAGTCTGAAATCGAAAATGAGATGAGTGTGCAAAAAGCACTTCTTGAAAAAGAAG
GGAAAAAGGCAGACCAAATTGAGAAGATCCTTCCTGGTAAAATGAAAAAATACTATGAAGACATTTGTCTCATCCACCAA
AAATCAATCCGTGACAACTCCAAAACCATCAATGACCTGCTCCAAGAGGCCATTGCAAAATTTGGAGAGAACATTACTGT
TGGTAGGTTCTCGAGGTTCCAAGTAGGTGGGAACTAG

Upstream 100 bases:

>100_bases
TCGCAAAAGACATCCCAGTGGATCCAGAAGCTGCTAAAAAAGTAGCAGAAGCTGTCGTAGAAGTTGTAACAGAAGAAAAA
CCAGCAGAAGGTAAAGAGTA

Downstream 100 bases:

>100_bases
TCCGCGTTTCAAACGAATCCTCATTAAAATCTCCGGCGAGGCACTCGCCGGTGAGGGTGAACTTGGTATTGATACCAACA
AAACATTCTCACTTGCCGGA

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MAVSSEQIKDLRERTGAGMMDCKKALEEKGGDIEKAVTYLREKGLAKAAKRAGRETGEGKVIAYVHGTGKTGVLVELNCE
TDFVANNEAFEALGKEIALQITAMSPLYVSEESIPKSEIENEMSVQKALLEKEGKKADQIEKILPGKMKKYYEDICLIHQ
KSIRDNSKTINDLLQEAIAKFGENITVGRFSRFQVGGN

Sequences:

>Translated_198_residues
MAVSSEQIKDLRERTGAGMMDCKKALEEKGGDIEKAVTYLREKGLAKAAKRAGRETGEGKVIAYVHGTGKTGVLVELNCE
TDFVANNEAFEALGKEIALQITAMSPLYVSEESIPKSEIENEMSVQKALLEKEGKKADQIEKILPGKMKKYYEDICLIHQ
KSIRDNSKTINDLLQEAIAKFGENITVGRFSRFQVGGN
>Mature_197_residues
AVSSEQIKDLRERTGAGMMDCKKALEEKGGDIEKAVTYLREKGLAKAAKRAGRETGEGKVIAYVHGTGKTGVLVELNCET
DFVANNEAFEALGKEIALQITAMSPLYVSEESIPKSEIENEMSVQKALLEKEGKKADQIEKILPGKMKKYYEDICLIHQK
SIRDNSKTINDLLQEAIAKFGENITVGRFSRFQVGGN

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI291084500, Length=198, Percent_Identity=34.3434343434343, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI291084502, Length=102, Percent_Identity=46.078431372549, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI291084498, Length=102, Percent_Identity=46.078431372549, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI171846268, Length=102, Percent_Identity=46.078431372549, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI1786366, Length=95, Percent_Identity=46.3157894736842, Blast_Score=93, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17561440, Length=198, Percent_Identity=29.7979797979798, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921466, Length=104, Percent_Identity=39.4230769230769, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_LEPBA (B0SDN6)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963598.1
- ProteinModelPortal:   B0SDN6
- SMR:   B0SDN6
- GeneID:   6387514
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2536
- HOGENOM:   HBG713289
- OMA:   MVELSCE
- ProtClustDB:   PRK12332
- BioCyc:   LBIF355278:LBF_2536-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 21831; Mature: 21700

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSSEQIKDLRERTGAGMMDCKKALEEKGGDIEKAVTYLREKGLAKAAKRAGRETGEGK
CCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VIAYVHGTGKTGVLVELNCETDFVANNEAFEALGKEIALQITAMSPLYVSEESIPKSEIE
EEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHEEEEEECCCEEECCCCCCHHHHH
NEMSVQKALLEKEGKKADQIEKILPGKMKKYYEDICLIHQKSIRDNSKTINDLLQEAIAK
HHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FGENITVGRFSRFQVGGN
HCCCCEECCCEEEECCCC
>Mature Secondary Structure 
AVSSEQIKDLRERTGAGMMDCKKALEEKGGDIEKAVTYLREKGLAKAAKRAGRETGEGK
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
VIAYVHGTGKTGVLVELNCETDFVANNEAFEALGKEIALQITAMSPLYVSEESIPKSEIE
EEEEEECCCCCCEEEEECCCCCCCCCCHHHHHHHHHHEEEEEECCCEEECCCCCCHHHHH
NEMSVQKALLEKEGKKADQIEKILPGKMKKYYEDICLIHQKSIRDNSKTINDLLQEAIAK
HHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
FGENITVGRFSRFQVGGN
HCCCCEECCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA