Click here to switch to the map view.

The map label for this gene is frr

Identifier: 183221973

GI number: 183221973

Start: 2705196

End: 2705747

Strand: Reverse

Name: frr

Synonym: LEPBI_I2614

Alternate gene names: 183221973

Gene position: 2705747-2705196 (Counterclockwise)

Preceding gene: 183221974

Following gene: 183221972

Centisome position: 75.17

GC content: 39.31

Gene sequence:

>552_bases
ATGGTAGATGAAATTATAAAATCCATGCAGTCCAAAATGGACAAAACAGTTGATGCCTTAAAAAAAGATTTTGGTACAAT
TCGTACGGGAAAAGCAAACCCTATGATGGTGGAAGATGTGAGAGTGGACTACTACGGAACACTCACTCCCTTAAACCAAC
TTGGTAAAATTGCATGCCCGGAACCGCGCGTGATTCTCATCACTCCTTTTGAAAAAGGAATGTTGAAAGACATCGAAAAA
GCAATTTTTGCAGCAAGTCTTGGACTCACACCGAATAACGATGGCTCCAGCATTCGTATCAATATCCCTGAACTCACGGG
AGAAAGACGAAAAGAGCTCGCAAAAGTGGTGAAACAAAAAGCGGAAGAAAAAAAAGTTGCGATTCGTAACATCCGTCGCG
ATGCCAATGATGAATTGAAAAAACACCAATCAGAAATGTCCCAAGATGAAGTGAAAGGCCACCAAGACAAAATCCAAAAA
ATTACGGATTCTTATATTGCCAAATTGGGAGATTTAGAAAAGGAAAAAGAAAAAGAGATCACAACTCTTTAA

Upstream 100 bases:

>100_bases
ATCATAGTGTTTGATATTTTTAAAGCAGGTAATTTAAGAAAATTGATCGATGGGGAACCAATTGGTACACTCATCTCCAA
TTCAGAGGAAGTGATTCTAG

Downstream 100 bases:

>100_bases
TTTCCTATGAAGTTGCATACGATCCCCGCGCACATTGCTGTCATTATGGACGGAAATGGTAGGTGGGCGGAAAACCAAGG
GAAAAAAAGAACCGAAGGCC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MVDEIIKSMQSKMDKTVDALKKDFGTIRTGKANPMMVEDVRVDYYGTLTPLNQLGKIACPEPRVILITPFEKGMLKDIEK
AIFAASLGLTPNNDGSSIRINIPELTGERRKELAKVVKQKAEEKKVAIRNIRRDANDELKKHQSEMSQDEVKGHQDKIQK
ITDSYIAKLGDLEKEKEKEITTL

Sequences:

>Translated_183_residues
MVDEIIKSMQSKMDKTVDALKKDFGTIRTGKANPMMVEDVRVDYYGTLTPLNQLGKIACPEPRVILITPFEKGMLKDIEK
AIFAASLGLTPNNDGSSIRINIPELTGERRKELAKVVKQKAEEKKVAIRNIRRDANDELKKHQSEMSQDEVKGHQDKIQK
ITDSYIAKLGDLEKEKEKEITTL
>Mature_183_residues
MVDEIIKSMQSKMDKTVDALKKDFGTIRTGKANPMMVEDVRVDYYGTLTPLNQLGKIACPEPRVILITPFEKGMLKDIEK
AIFAASLGLTPNNDGSSIRINIPELTGERRKELAKVVKQKAEEKKVAIRNIRRDANDELKKHQSEMSQDEVKGHQDKIQK
ITDSYIAKLGDLEKEKEKEITTL

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=184, Percent_Identity=27.7173913043478, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI291042689, Length=132, Percent_Identity=31.0606060606061, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=43.956043956044, Blast_Score=160, Evalue=6e-41,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=28.1609195402299, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_LEPBA (B0SDN4)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001963596.1
- ProteinModelPortal:   B0SDN4
- SMR:   B0SDN4
- GeneID:   6388985
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_2534
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- ProtClustDB:   PRK00083
- BioCyc:   LBIF355278:LBF_2534-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20697; Mature: 20697

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDEIIKSMQSKMDKTVDALKKDFGTIRTGKANPMMVEDVRVDYYGTLTPLNQLGKIACP
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHEEECCCCCCCCHHHCCCCCCC
EPRVILITPFEKGMLKDIEKAIFAASLGLTPNNDGSSIRINIPELTGERRKELAKVVKQK
CCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AEEKKVAIRNIRRDANDELKKHQSEMSQDEVKGHQDKIQKITDSYIAKLGDLEKEKEKEI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHC
TTL
CCC
>Mature Secondary Structure
MVDEIIKSMQSKMDKTVDALKKDFGTIRTGKANPMMVEDVRVDYYGTLTPLNQLGKIACP
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEHEEECCCCCCCCHHHCCCCCCC
EPRVILITPFEKGMLKDIEKAIFAASLGLTPNNDGSSIRINIPELTGERRKELAKVVKQK
CCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHH
AEEKKVAIRNIRRDANDELKKHQSEMSQDEVKGHQDKIQKITDSYIAKLGDLEKEKEKEI
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHC
TTL
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA