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The map label for this gene is pdtaS [H]

Identifier: 183221956

GI number: 183221956

Start: 2683764

End: 2685311

Strand: Direct

Name: pdtaS [H]

Synonym: LEPBI_I2597

Alternate gene names: 183221956

Gene position: 2683764-2685311 (Clockwise)

Preceding gene: 183221949

Following gene: 183221958

Centisome position: 74.56

GC content: 37.34

Gene sequence:

>1548_bases
GTGAAAGTTCGAAATCGTAATCTAGATCCAGAACGCATAGCAGACTTCGAAAGTTTCCGAAGTGGGATCCTCGAACTCAT
TGTCAAAAATAAACCCTTATCAGAAATTTTAAACGAAATCGTATTCGGAATTGAAACACTGAATCCTACGATGGTCTGCA
CCATTGTTCTCATAGAGGATTCCAAAATCAAAATTGGAGCGGCCCCATCCCTACCTAAAGATTACAACGATACCATCGAA
GGAGTCACCATCGGACCTGAAGTTGGTTCTTGTGGAACGGCAGCATACACAGGAAAACGAGTCATCGTCGAGGACATCAA
CAAAAGCCATTTATGGAAAAACTACAAGGAGATCGCTCTCAAAGTAGGACTTCTTGCTTGTTGGTCGGAACCAATTCGCT
CTCATGGAGATACCGTTGTTGGTACTTTTGCGATCTACCATCATCAAATTGCAAGCCCAAGTGAATTTGATATCTTTATC
ATTTCTGAAACTGCGGACCTTGTGAGCATTGCCATCGATAAATCCACGACTTCCTCCAAACTCACAGAAAGTGAAAAACG
TTTCAGGGATTTTTTTGAAAAAAACTCTTCGATGATCCTCATCATCGAACCAATCACAGGCGACATTTATGATGCCAATG
AAGCAGCAGTTTTATTTTATGGTTTCCCACATGAACAAATCATCAAAATGAACATTGATTCGATCAATGTAATGAATCAA
GATGATTTAAAAAAAGAAAGATTATTGGCAATTGCGGAAAACAAAAGTTTTTTTACCTTCACACACAAATTAGCAGATGG
GCAAACCAAACAGGTGGAAGTGTATTCGACACCGATTGAATCCAACAACCGCCCTCTGCTTTTTTCGATCATTCATGATG
TAACAGAACGAAAAATCGCAGAAGAAAAGGTAAATGCACTACTTTCCGAAAAGGAAATGATCCTAAGAGAAGTACATCAT
CGTATCAAAAACAATATGACGATTCTCAATAATCTTTTACAATTACAAGCAAGTGCAAACGAAAGTGAAGAAGTACGAAA
TTCTCTAAAAGAAGCAACCAGTCGAATCAAAACAATGTCTCTACTCTACGACAAATTGTATTCAGGAAAAATAAACCAGG
AACTAAGCCTGTATGAGTATCTAGTACCTTTAACCAATGAAATCCTTTCCTTATTTCCATATCCTGTGCAGTTACAAATG
AAAGTAGAAAACATCATGATGGCTTCGGAGCAACTTCAAGCGATTGGAATCATCACAAACGAACTTTTGACCAATAGTTT
GAAGTATGCAAGAAACACTGCACACGAATTGGAAATTCGTGTAAATGCTTGGTTAAACGATTCCATTTTTTATCTCATCA
TCTGTGACAATGGAAATGGTTTTCATCTCAACGATTCAAATGAAGAAACCAATGGATTTGGTTTGAATTTGGTAAAAATG
TTAACCAAACAATTTAAAGGTAATCTATCTTTTAATGGAGAGAAAGGTGCCGAGTACCAATTCAAATTTCCACTAACTTT
ATCCAATCACAATTCAAACAGACTTTAG

Upstream 100 bases:

>100_bases
TTCTCGCCAGGCGTTCCACGTAAGCTAACTGGCTGTATATGGATTCATATTGACATGTTTTTTTTCGTCGTAATGATCAT
GGTCAAAAGGTGGGGATTTT

Downstream 100 bases:

>100_bases
AATTTCAAAAAATCCAGGGAAACTTGTATCCACCCAACTTGTATCGTCAAAAGAAAGTGAAACGCCTGATAATTTGGATA
GGATCGCAAAACTCATCGCA

Product: putative signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MKVRNRNLDPERIADFESFRSGILELIVKNKPLSEILNEIVFGIETLNPTMVCTIVLIEDSKIKIGAAPSLPKDYNDTIE
GVTIGPEVGSCGTAAYTGKRVIVEDINKSHLWKNYKEIALKVGLLACWSEPIRSHGDTVVGTFAIYHHQIASPSEFDIFI
ISETADLVSIAIDKSTTSSKLTESEKRFRDFFEKNSSMILIIEPITGDIYDANEAAVLFYGFPHEQIIKMNIDSINVMNQ
DDLKKERLLAIAENKSFFTFTHKLADGQTKQVEVYSTPIESNNRPLLFSIIHDVTERKIAEEKVNALLSEKEMILREVHH
RIKNNMTILNNLLQLQASANESEEVRNSLKEATSRIKTMSLLYDKLYSGKINQELSLYEYLVPLTNEILSLFPYPVQLQM
KVENIMMASEQLQAIGIITNELLTNSLKYARNTAHELEIRVNAWLNDSIFYLIICDNGNGFHLNDSNEETNGFGLNLVKM
LTKQFKGNLSFNGEKGAEYQFKFPLTLSNHNSNRL

Sequences:

>Translated_515_residues
MKVRNRNLDPERIADFESFRSGILELIVKNKPLSEILNEIVFGIETLNPTMVCTIVLIEDSKIKIGAAPSLPKDYNDTIE
GVTIGPEVGSCGTAAYTGKRVIVEDINKSHLWKNYKEIALKVGLLACWSEPIRSHGDTVVGTFAIYHHQIASPSEFDIFI
ISETADLVSIAIDKSTTSSKLTESEKRFRDFFEKNSSMILIIEPITGDIYDANEAAVLFYGFPHEQIIKMNIDSINVMNQ
DDLKKERLLAIAENKSFFTFTHKLADGQTKQVEVYSTPIESNNRPLLFSIIHDVTERKIAEEKVNALLSEKEMILREVHH
RIKNNMTILNNLLQLQASANESEEVRNSLKEATSRIKTMSLLYDKLYSGKINQELSLYEYLVPLTNEILSLFPYPVQLQM
KVENIMMASEQLQAIGIITNELLTNSLKYARNTAHELEIRVNAWLNDSIFYLIICDNGNGFHLNDSNEETNGFGLNLVKM
LTKQFKGNLSFNGEKGAEYQFKFPLTLSNHNSNRL
>Mature_515_residues
MKVRNRNLDPERIADFESFRSGILELIVKNKPLSEILNEIVFGIETLNPTMVCTIVLIEDSKIKIGAAPSLPKDYNDTIE
GVTIGPEVGSCGTAAYTGKRVIVEDINKSHLWKNYKEIALKVGLLACWSEPIRSHGDTVVGTFAIYHHQIASPSEFDIFI
ISETADLVSIAIDKSTTSSKLTESEKRFRDFFEKNSSMILIIEPITGDIYDANEAAVLFYGFPHEQIIKMNIDSINVMNQ
DDLKKERLLAIAENKSFFTFTHKLADGQTKQVEVYSTPIESNNRPLLFSIIHDVTERKIAEEKVNALLSEKEMILREVHH
RIKNNMTILNNLLQLQASANESEEVRNSLKEATSRIKTMSLLYDKLYSGKINQELSLYEYLVPLTNEILSLFPYPVQLQM
KVENIMMASEQLQAIGIITNELLTNSLKYARNTAHELEIRVNAWLNDSIFYLIICDNGNGFHLNDSNEETNGFGLNLVKM
LTKQFKGNLSFNGEKGAEYQFKFPLTLSNHNSNRL

Specific function: Member of the two-component regulatory system pdtaR/pdtaS. Autophosphorylates, probably on a histidine residue, and transfers its phosphate group to pdtaR [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=145, Percent_Identity=32.4137931034483, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR022066
- InterPro:   IPR011495
- InterPro:   IPR005467 [H]

Pfam domain/function: PF12282 H_kinase_N; PF02518 HATPase_c; PF07568 HisKA_2 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58370; Mature: 58370

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRNRNLDPERIADFESFRSGILELIVKNKPLSEILNEIVFGIETLNPTMVCTIVLIED
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEC
SKIKIGAAPSLPKDYNDTIEGVTIGPEVGSCGTAAYTGKRVIVEDINKSHLWKNYKEIAL
CEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCHHHCCCEEEEECCCHHHHHHHHHHHHH
KVGLLACWSEPIRSHGDTVVGTFAIYHHQIASPSEFDIFIISETADLVSIAIDKSTTSSK
HHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCHHH
LTESEKRFRDFFEKNSSMILIIEPITGDIYDANEAAVLFYGFPHEQIIKMNIDSINVMNQ
HHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCEEEEEECCCCEEEEEECCEEECCCC
DDLKKERLLAIAENKSFFTFTHKLADGQTKQVEVYSTPIESNNRPLLFSIIHDVTERKIA
HHHHHHHEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHH
EEKVNALLSEKEMILREVHHRIKNNMTILNNLLQLQASANESEEVRNSLKEATSRIKTMS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LLYDKLYSGKINQELSLYEYLVPLTNEILSLFPYPVQLQMKVENIMMASEQLQAIGIITN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
ELLTNSLKYARNTAHELEIRVNAWLNDSIFYLIICDNGNGFHLNDSNEETNGFGLNLVKM
HHHHHHHHHHHCCCEEEEEEEEEEECCCEEEEEEEECCCEEEECCCCCCCCCCCHHHHHH
LTKQFKGNLSFNGEKGAEYQFKFPLTLSNHNSNRL
HHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCC
>Mature Secondary Structure
MKVRNRNLDPERIADFESFRSGILELIVKNKPLSEILNEIVFGIETLNPTMVCTIVLIED
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEEEEC
SKIKIGAAPSLPKDYNDTIEGVTIGPEVGSCGTAAYTGKRVIVEDINKSHLWKNYKEIAL
CEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCHHHCCCEEEEECCCHHHHHHHHHHHHH
KVGLLACWSEPIRSHGDTVVGTFAIYHHQIASPSEFDIFIISETADLVSIAIDKSTTSSK
HHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCEEEEEEECCCCEEEEEECCCCCHHH
LTESEKRFRDFFEKNSSMILIIEPITGDIYDANEAAVLFYGFPHEQIIKMNIDSINVMNQ
HHHHHHHHHHHHHCCCCEEEEEECCCCCEECCCCCEEEEEECCCCEEEEEECCEEECCCC
DDLKKERLLAIAENKSFFTFTHKLADGQTKQVEVYSTPIESNNRPLLFSIIHDVTERKIA
HHHHHHHEEEEECCCCEEEEEEECCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHH
EEKVNALLSEKEMILREVHHRIKNNMTILNNLLQLQASANESEEVRNSLKEATSRIKTMS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LLYDKLYSGKINQELSLYEYLVPLTNEILSLFPYPVQLQMKVENIMMASEQLQAIGIITN
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHH
ELLTNSLKYARNTAHELEIRVNAWLNDSIFYLIICDNGNGFHLNDSNEETNGFGLNLVKM
HHHHHHHHHHHCCCEEEEEEEEEEECCCEEEEEEEECCCEEEECCCCCCCCCCCHHHHHH
LTKQFKGNLSFNGEKGAEYQFKFPLTLSNHNSNRL
HHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]