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The map label for this gene is qor [H]

Identifier: 183221844

GI number: 183221844

Start: 2558230

End: 2559234

Strand: Direct

Name: qor [H]

Synonym: LEPBI_I2475

Alternate gene names: 183221844

Gene position: 2558230-2559234 (Clockwise)

Preceding gene: 183221842

Following gene: 183221850

Centisome position: 71.07

GC content: 37.81

Gene sequence:

>1005_bases
TTGACATACTTACACTGTAAGTCATTTTCGAAATCTGGAGTTTACCCTTTGAAAGTTATCACTTATCGTAATTATGGCCC
ACCTGAAGTATTAAAATTAGAAAATTGGGAGATTCCGAATCCAAAAGAGGATCAAATTCGAGTTCGTATTGTCAATACGG
CTGTGAATTCTGGAGATTGGAGGATGCGTAAACCTGATCCGAAAGTAGTTCGTTTATTCTTCGGATTATTCAAACCAAGA
TCTGTCATTTTAGGGATAAGTTTTGCCGGAATTGTGGATGCAGTGGGGAAAAATGTAAAATCCTTTCAGATTGGTGACAA
GGTTCTTGGTTCCACTGGAATGAAGATGGGAGCATATGCTGAATATACCTGTGTATCTGAAAACGCGGTTGTCTCAAAAC
TACCAGAAAAAATGTCTTTTCCAGAAGGAGCCGCCATATCATTCGGTGGCCTCACTGCAGTAGATTTTATACAAAGATGT
AAAATCCAAACAAACCAAACCATTGTCATTTACGGAGCTTCCAGTTCCGTCGGAACATCGGCCATCCAATTGGCAAAACA
TTTTGGTGCTCACGTAACTGCCGTTTGTAGCCAAGGGAATTTTGAGTTGGTAACATCACTCGGAGCAGACAAAACAATGG
ATTATTCAAATTTTTTTGCTTCAAATGAACAATATGATGTCGTTTTTGAATGTGTCGGAAAAACAGAAATTGAAACAGAT
TTGAAATACCTAAAAAAAGGTGGGCATTTAGTGTTAGTTGGTGCTTCGTTTCGGCAAATGTGGGATTCGATTTGGATTTC
TCTATTCCAACGAATTCAAATTCACATTGGTCCCATCAAAGAAACATTAGAAAATTTAAACTTTTTACTCACTTTGGCAA
ATCTCGGCAAATACAAAGTGGCCATTGATAGAAGTTATCCATTAGAAGAAATGGTAGAAGCACACAGGTATGTTGAAGCA
GGTCATAAAAAGGGAAATGTTGTGATTGATGTTAGCAAGGTTTAA

Upstream 100 bases:

>100_bases
CTGAATTGCTCCTAAAAGTTTGTCAGCATATCTCATTTATCTATCATAAAATTCACTACTGATCGAGACAAAATTTTCAT
TTTTAAGGAAATATATTTCA

Downstream 100 bases:

>100_bases
TACGTATGGAGAAAGCCCACCTAATCTACATTAGACAGGCTTTCGGATACATTAGTTGAATTTGAATGTTGGTGAGTTGT
TTTGTTTTTTAGTGCCCAAG

Product: putative alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTYLHCKSFSKSGVYPLKVITYRNYGPPEVLKLENWEIPNPKEDQIRVRIVNTAVNSGDWRMRKPDPKVVRLFFGLFKPR
SVILGISFAGIVDAVGKNVKSFQIGDKVLGSTGMKMGAYAEYTCVSENAVVSKLPEKMSFPEGAAISFGGLTAVDFIQRC
KIQTNQTIVIYGASSSVGTSAIQLAKHFGAHVTAVCSQGNFELVTSLGADKTMDYSNFFASNEQYDVVFECVGKTEIETD
LKYLKKGGHLVLVGASFRQMWDSIWISLFQRIQIHIGPIKETLENLNFLLTLANLGKYKVAIDRSYPLEEMVEAHRYVEA
GHKKGNVVIDVSKV

Sequences:

>Translated_334_residues
MTYLHCKSFSKSGVYPLKVITYRNYGPPEVLKLENWEIPNPKEDQIRVRIVNTAVNSGDWRMRKPDPKVVRLFFGLFKPR
SVILGISFAGIVDAVGKNVKSFQIGDKVLGSTGMKMGAYAEYTCVSENAVVSKLPEKMSFPEGAAISFGGLTAVDFIQRC
KIQTNQTIVIYGASSSVGTSAIQLAKHFGAHVTAVCSQGNFELVTSLGADKTMDYSNFFASNEQYDVVFECVGKTEIETD
LKYLKKGGHLVLVGASFRQMWDSIWISLFQRIQIHIGPIKETLENLNFLLTLANLGKYKVAIDRSYPLEEMVEAHRYVEA
GHKKGNVVIDVSKV
>Mature_333_residues
TYLHCKSFSKSGVYPLKVITYRNYGPPEVLKLENWEIPNPKEDQIRVRIVNTAVNSGDWRMRKPDPKVVRLFFGLFKPRS
VILGISFAGIVDAVGKNVKSFQIGDKVLGSTGMKMGAYAEYTCVSENAVVSKLPEKMSFPEGAAISFGGLTAVDFIQRCK
IQTNQTIVIYGASSSVGTSAIQLAKHFGAHVTAVCSQGNFELVTSLGADKTMDYSNFFASNEQYDVVFECVGKTEIETDL
KYLKKGGHLVLVGASFRQMWDSIWISLFQRIQIHIGPIKETLENLNFLLTLANLGKYKVAIDRSYPLEEMVEAHRYVEAG
HKKGNVVIDVSKV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=331, Percent_Identity=27.4924471299094, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI13236495, Length=331, Percent_Identity=27.4924471299094, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI47519420, Length=365, Percent_Identity=30.1369863013699, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI194239676, Length=315, Percent_Identity=27.3015873015873, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI22538446, Length=343, Percent_Identity=25.0728862973761, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI22538444, Length=343, Percent_Identity=25.0728862973761, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI24308257, Length=363, Percent_Identity=25.3443526170799, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI18379349, Length=323, Percent_Identity=24.1486068111455, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=335, Percent_Identity=25.9701492537313, Blast_Score=85, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=342, Percent_Identity=26.6081871345029, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71988145, Length=346, Percent_Identity=25.1445086705202, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=338, Percent_Identity=24.8520710059172, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6323961, Length=347, Percent_Identity=24.207492795389, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24581339, Length=354, Percent_Identity=27.683615819209, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581341, Length=354, Percent_Identity=27.683615819209, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 37112; Mature: 36981

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYLHCKSFSKSGVYPLKVITYRNYGPPEVLKLENWEIPNPKEDQIRVRIVNTAVNSGDW
CCEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCC
RMRKPDPKVVRLFFGLFKPRSVILGISFAGIVDAVGKNVKSFQIGDKVLGSTGMKMGAYA
EEECCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCEEECCHHHHCCCCCCCCCCE
EYTCVSENAVVSKLPEKMSFPEGAAISFGGLTAVDFIQRCKIQTNQTIVIYGASSSVGTS
EEEEECCCHHHHHCHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
AIQLAKHFGAHVTAVCSQGNFELVTSLGADKTMDYSNFFASNEQYDVVFECVGKTEIETD
HHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHH
LKYLKKGGHLVLVGASFRQMWDSIWISLFQRIQIHIGPIKETLENLNFLLTLANLGKYKV
HHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHEEEEEECCCCEEE
AIDRSYPLEEMVEAHRYVEAGHKKGNVVIDVSKV
EEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECC
>Mature Secondary Structure 
TYLHCKSFSKSGVYPLKVITYRNYGPPEVLKLENWEIPNPKEDQIRVRIVNTAVNSGDW
CEEEECCCCCCCCCEEEEEEECCCCCCCEEEECCCCCCCCCCCCEEEEEEEEEECCCCC
RMRKPDPKVVRLFFGLFKPRSVILGISFAGIVDAVGKNVKSFQIGDKVLGSTGMKMGAYA
EEECCCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHCCCCCEEECCHHHHCCCCCCCCCCE
EYTCVSENAVVSKLPEKMSFPEGAAISFGGLTAVDFIQRCKIQTNQTIVIYGASSSVGTS
EEEEECCCHHHHHCHHHHCCCCCCEEECCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHH
AIQLAKHFGAHVTAVCSQGNFELVTSLGADKTMDYSNFFASNEQYDVVFECVGKTEIETD
HHHHHHHHCCEEEEEECCCCEEEEEECCCCCCCCHHHHHCCCCCCEEEEEECCCCHHHHH
LKYLKKGGHLVLVGASFRQMWDSIWISLFQRIQIHIGPIKETLENLNFLLTLANLGKYKV
HHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHEEEECHHHHHHHHHHEEEEEECCCCEEE
AIDRSYPLEEMVEAHRYVEAGHKKGNVVIDVSKV
EEECCCCHHHHHHHHHHHHCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]