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The map label for this gene is kefG [H]

Identifier: 183221506

GI number: 183221506

Start: 2216691

End: 2217236

Strand: Reverse

Name: kefG [H]

Synonym: LEPBI_I2124

Alternate gene names: 183221506

Gene position: 2217236-2216691 (Counterclockwise)

Preceding gene: 183221508

Following gene: 183221505

Centisome position: 61.6

GC content: 37.73

Gene sequence:

>546_bases
ATGGCAAAGATTCTCATTTTACTCGTCCATCCAAATCTGGAACGTTCCAAAGCAAATCAAATGTTATTAGATTCCTTACC
AGTTTCTGACAATATCACATTACGAGATTTATACGAATTATACCCTCATTTTACTATCAATGTGAAAGAAGAACAAACTC
TCTTACAAAACCATGATGTCATTTTATTCCAACATCCATTTTATTGGTACAGTTGTCCACCGCTCATGAAACAATGGATC
GATGCCGTCTTAGAAGATGGTTGGGCCTATGGTAAAAATGGGAATGCTTTGAAAGGTAAAAAATGGATCCAAGCGATTTC
CACTGGAGGTTCCGAAAAGGCCTATCAAAAAGATGGATTCCATGGTCATTTGATTGATGCGTTTCTTTTGCCGTTCCAAA
GGACCGCAGAACTTTGCCAGATGGAATACCAAAAACCATTTTTAGTCCAAGGTACATTCCAATTGAAAGAAGAGGAGTTC
CAAAAAGAATCCATCCGTTATCGAAATTTCATTCTCTCTCATTTAGAGGAGGTTTACAATGGGTGA

Upstream 100 bases:

>100_bases
TTTTCACTCATGACTAAACTGGTTTTTTTTTGAAAATGGTCAATTGAAATCAGGATTTTATGGTTTGCCTCTCATTTTAT
CCTTTGTTCTTTGCACTTGT

Downstream 100 bases:

>100_bases
AGTTAATTTTTTCATTCAGGCCATCATCTATCTCACAAGTGCCATCATCATTGTTCCAATCGCCAATCGTTTGGGTCTTG
GTTCCGTGCTTGGTTATTTG

Product: NAD(P)H dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MAKILILLVHPNLERSKANQMLLDSLPVSDNITLRDLYELYPHFTINVKEEQTLLQNHDVILFQHPFYWYSCPPLMKQWI
DAVLEDGWAYGKNGNALKGKKWIQAISTGGSEKAYQKDGFHGHLIDAFLLPFQRTAELCQMEYQKPFLVQGTFQLKEEEF
QKESIRYRNFILSHLEEVYNG

Sequences:

>Translated_181_residues
MAKILILLVHPNLERSKANQMLLDSLPVSDNITLRDLYELYPHFTINVKEEQTLLQNHDVILFQHPFYWYSCPPLMKQWI
DAVLEDGWAYGKNGNALKGKKWIQAISTGGSEKAYQKDGFHGHLIDAFLLPFQRTAELCQMEYQKPFLVQGTFQLKEEEF
QKESIRYRNFILSHLEEVYNG
>Mature_180_residues
AKILILLVHPNLERSKANQMLLDSLPVSDNITLRDLYELYPHFTINVKEEQTLLQNHDVILFQHPFYWYSCPPLMKQWID
AVLEDGWAYGKNGNALKGKKWIQAISTGGSEKAYQKDGFHGHLIDAFLLPFQRTAELCQMEYQKPFLVQGTFQLKEEEFQ
KESIRYRNFILSHLEEVYNG

Specific function: Required for full activity of kefB [H]

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily [H]

Homologues:

Organism=Homo sapiens, GI156564357, Length=105, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1789750, Length=175, Percent_Identity=38.8571428571429, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786231, Length=178, Percent_Identity=37.6404494382022, Blast_Score=135, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003680 [H]

Pfam domain/function: PF02525 Flavodoxin_2 [H]

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21208; Mature: 21076

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILILLVHPNLERSKANQMLLDSLPVSDNITLRDLYELYPHFTINVKEEQTLLQNHDV
CCEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEECHHHHHHHCCCE
ILFQHPFYWYSCPPLMKQWIDAVLEDGWAYGKNGNALKGKKWIQAISTGGSEKAYQKDGF
EEEECCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCC
HGHLIDAFLLPFQRTAELCQMEYQKPFLVQGTFQLKEEEFQKESIRYRNFILSHLEEVYN
CHHHHHHHHCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
G
C
>Mature Secondary Structure 
AKILILLVHPNLERSKANQMLLDSLPVSDNITLRDLYELYPHFTINVKEEQTLLQNHDV
CEEEEEEECCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEECHHHHHHHCCCE
ILFQHPFYWYSCPPLMKQWIDAVLEDGWAYGKNGNALKGKKWIQAISTGGSEKAYQKDGF
EEEECCCCEECCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHCCCC
HGHLIDAFLLPFQRTAELCQMEYQKPFLVQGTFQLKEEEFQKESIRYRNFILSHLEEVYN
CHHHHHHHHCCHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA