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The map label for this gene is hupR1 [H]

Identifier: 183221500

GI number: 183221500

Start: 2211725

End: 2212084

Strand: Reverse

Name: hupR1 [H]

Synonym: LEPBI_I2118

Alternate gene names: 183221500

Gene position: 2212084-2211725 (Counterclockwise)

Preceding gene: 183221501

Following gene: 183221498

Centisome position: 61.45

GC content: 37.5

Gene sequence:

>360_bases
TTGAAACCAAAACTACTTTATGTGGATGATGAAGTCATGAATTTACATCTATTCCGAGAAATGTTTCGAAAGGATTTTGA
TGTTTTGATTGCAAGTTCTGGGGAGGAAGCCTTAGAAGAATTGGAAGAATCAAAAGAAATCCAATATGTAATTACCGATA
TGAGAATGCCTGAAATGAATGGACTCGAATTGATTTCAAAAGCGAAAAAGGTTCGTCCAGAAGTGGTGTATTGTTTGTTA
ACCGGTTACGATCTAACCAAAGAAATTGAAAAAGCAATCGAAGCAAAACAAGTGGCTCGTTATTTTGCAAAACCATTTGA
CCCCACAGAGATTCGAACCTTTCTCTCTGCGGGCCAGTAG

Upstream 100 bases:

>100_bases
AATTTTGAAAGAACATTCGGCATCAATTGATGTGGAATCGGAATGGGGGGAGGGGACAAAATTTACGATCCGTCTTCCCA
AATGGAATGAAGGTTAAATT

Downstream 100 bases:

>100_bases
ATCCAATAAGTGTTTTACTTACTTGTTTTTAAACTCAATTTCGACAACTCCGCGTTTGGAACTGTTGATGTTTAACGTTT
TATTGCTTAAGAAACGGAAA

Product: putative two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 119; Mature: 119

Protein sequence:

>119_residues
MKPKLLYVDDEVMNLHLFREMFRKDFDVLIASSGEEALEELEESKEIQYVITDMRMPEMNGLELISKAKKVRPEVVYCLL
TGYDLTKEIEKAIEAKQVARYFAKPFDPTEIRTFLSAGQ

Sequences:

>Translated_119_residues
MKPKLLYVDDEVMNLHLFREMFRKDFDVLIASSGEEALEELEESKEIQYVITDMRMPEMNGLELISKAKKVRPEVVYCLL
TGYDLTKEIEKAIEAKQVARYFAKPFDPTEIRTFLSAGQ
>Mature_119_residues
MKPKLLYVDDEVMNLHLFREMFRKDFDVLIASSGEEALEELEESKEIQYVITDMRMPEMNGLELISKAKKVRPEVVYCLL
TGYDLTKEIEKAIEAKQVARYFAKPFDPTEIRTFLSAGQ

Specific function: Probable member of the two-component regulatory system involved in the regulation of the [NiFe] hydrogenase activity. HupR1 is probably phosphorylated by the sensory component and then acts in conjunction with sigma-54 as a transcriptional activator [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 13855; Mature: 13855

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKLLYVDDEVMNLHLFREMFRKDFDVLIASSGEEALEELEESKEIQYVITDMRMPEMN
CCCCEEEECHHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GLELISKAKKVRPEVVYCLLTGYDLTKEIEKAIEAKQVARYFAKPFDPTEIRTFLSAGQ
HHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKPKLLYVDDEVMNLHLFREMFRKDFDVLIASSGEEALEELEESKEIQYVITDMRMPEMN
CCCCEEEECHHHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCC
GLELISKAKKVRPEVVYCLLTGYDLTKEIEKAIEAKQVARYFAKPFDPTEIRTFLSAGQ
HHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1885559; 8497190; 2007559 [H]