Click here to switch to the map view.

The map label for this gene is ybbO [C]

Identifier: 183221431

GI number: 183221431

Start: 2132226

End: 2132984

Strand: Reverse

Name: ybbO [C]

Synonym: LEPBI_I2049

Alternate gene names: 183221431

Gene position: 2132984-2132226 (Counterclockwise)

Preceding gene: 183221445

Following gene: 183221430

Centisome position: 59.25

GC content: 38.34

Gene sequence:

>759_bases
ATGGAATTAAAAAATAAACGTATCGTAGTCACTGGAGCAGGTTCTGGTATTGGAAAAGAAACCGTCTTACAGATGTTAAA
ACATGGGAATGTAAAAATTTTAGCTTGTGACTTAAACGAAAAAAATGTGGTTTCTCATCCCAATGTAATTCCGTATAAAT
GTGATGTATCGAAACCAGAATCCTTAGATAAACTGATAAAGGATGCAGATAAAAAATTGGGTGGCATTGATATCTTTTTT
GCCAACGCAGGATTTGCTTATTACGAAATCATTCCTGATGCCAATTGGGATCGAATCGATCGTATCTTTCGAACCAATGT
ATTTTCTCCATTATATACCCTTGTGACTTTGAACAGGCAAAGGACCACTCCTTGTCTTTTTGTCGTGACTGCCTCTGCCA
TGAGTCACTTGCCACTGCCAGGATATGCCATGTATTCGGCAACGAAAGCAGCCGTTCGGTCCTTTCTTGATGCCTACCAA
TGTGAATTGAGACCTGGAAATCGAACGATGATCGTGTACCCGATTGCGACTAGGACACAATTTTTTGACTCTGCAGGGAA
AAAAGTCCCTATTCCGTTTCCAAGCCAAACGGCCGAAACAGTAGCAAAACAAATTGTGAAAGGAATCTTAAGCGACAAAA
AAGAGGTTTTCCCTTCCTTTTTATTTCGTTTCATCCAAATCTTGGACCGATTTTTATTTTTCCCTTTGAAAATTTACCAA
AAAATGGAAGCAGTAAAATTGAATTCGCATAAATCTTAA

Upstream 100 bases:

>100_bases
ATACTAGCTTCGTAAAGAGATTTTTCCTGAATTAGGAAAAAAGTTAGATATCTTATTAAAAAAAACTTTCAACAGAAGTC
CAGTTCGTTAGGTTTCAACA

Downstream 100 bases:

>100_bases
GTATACTGCATAGTGGATACTATGCAGTCTTCTCAGGAAGGATCATTGCCTCAAATAACAGCTTCGACAGACGATCATTT
GAATGTCGAAGCAGATCTTT

Product: putative short-chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MELKNKRIVVTGAGSGIGKETVLQMLKHGNVKILACDLNEKNVVSHPNVIPYKCDVSKPESLDKLIKDADKKLGGIDIFF
ANAGFAYYEIIPDANWDRIDRIFRTNVFSPLYTLVTLNRQRTTPCLFVVTASAMSHLPLPGYAMYSATKAAVRSFLDAYQ
CELRPGNRTMIVYPIATRTQFFDSAGKKVPIPFPSQTAETVAKQIVKGILSDKKEVFPSFLFRFIQILDRFLFFPLKIYQ
KMEAVKLNSHKS

Sequences:

>Translated_252_residues
MELKNKRIVVTGAGSGIGKETVLQMLKHGNVKILACDLNEKNVVSHPNVIPYKCDVSKPESLDKLIKDADKKLGGIDIFF
ANAGFAYYEIIPDANWDRIDRIFRTNVFSPLYTLVTLNRQRTTPCLFVVTASAMSHLPLPGYAMYSATKAAVRSFLDAYQ
CELRPGNRTMIVYPIATRTQFFDSAGKKVPIPFPSQTAETVAKQIVKGILSDKKEVFPSFLFRFIQILDRFLFFPLKIYQ
KMEAVKLNSHKS
>Mature_252_residues
MELKNKRIVVTGAGSGIGKETVLQMLKHGNVKILACDLNEKNVVSHPNVIPYKCDVSKPESLDKLIKDADKKLGGIDIFF
ANAGFAYYEIIPDANWDRIDRIFRTNVFSPLYTLVTLNRQRTTPCLFVVTASAMSHLPLPGYAMYSATKAAVRSFLDAYQ
CELRPGNRTMIVYPIATRTQFFDSAGKKVPIPFPSQTAETVAKQIVKGILSDKKEVFPSFLFRFIQILDRFLFFPLKIYQ
KMEAVKLNSHKS

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4503817, Length=236, Percent_Identity=30.0847457627119, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40807363, Length=249, Percent_Identity=25.7028112449799, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI210032110, Length=240, Percent_Identity=24.1666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786701, Length=265, Percent_Identity=27.1698113207547, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=252, Percent_Identity=28.5714285714286, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17567345, Length=236, Percent_Identity=22.4576271186441, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323458, Length=217, Percent_Identity=31.7972350230415, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322067, Length=283, Percent_Identity=25.0883392226148, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI21355631, Length=256, Percent_Identity=30.078125, Blast_Score=94, Evalue=7e-20,
Organism=Drosophila melanogaster, GI281364892, Length=238, Percent_Identity=27.3109243697479, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28571526, Length=198, Percent_Identity=30.8080808080808, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28421; Mature: 28421

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKNKRIVVTGAGSGIGKETVLQMLKHGNVKILACDLNEKNVVSHPNVIPYKCDVSKPE
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCH
SLDKLIKDADKKLGGIDIFFANAGFAYYEIIPDANWDRIDRIFRTNVFSPLYTLVTLNRQ
HHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RTTPCLFVVTASAMSHLPLPGYAMYSATKAAVRSFLDAYQCELRPGNRTMIVYPIATRTQ
CCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCHHHH
FFDSAGKKVPIPFPSQTAETVAKQIVKGILSDKKEVFPSFLFRFIQILDRFLFFPLKIYQ
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMEAVKLNSHKS
HHHHHHCCCCCC
>Mature Secondary Structure
MELKNKRIVVTGAGSGIGKETVLQMLKHGNVKILACDLNEKNVVSHPNVIPYKCDVSKPE
CCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEEECCCCCH
SLDKLIKDADKKLGGIDIFFANAGFAYYEIIPDANWDRIDRIFRTNVFSPLYTLVTLNRQ
HHHHHHHHHHHHCCCEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
RTTPCLFVVTASAMSHLPLPGYAMYSATKAAVRSFLDAYQCELRPGNRTMIVYPIATRTQ
CCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEECCHHHH
FFDSAGKKVPIPFPSQTAETVAKQIVKGILSDKKEVFPSFLFRFIQILDRFLFFPLKIYQ
HHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMEAVKLNSHKS
HHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]