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The map label for this gene is rfbB [H]

Identifier: 183221399

GI number: 183221399

Start: 2098393

End: 2099673

Strand: Reverse

Name: rfbB [H]

Synonym: LEPBI_I2017

Alternate gene names: 183221399

Gene position: 2099673-2098393 (Counterclockwise)

Preceding gene: 183221400

Following gene: 183221398

Centisome position: 58.33

GC content: 36.46

Gene sequence:

>1281_bases
ATGAGTGATGTAGTTTTACGAATAGATAATATCTCCAAACAATACAGATTGGGTCAAATAAGCACAGGTTCTTTGGCTCA
TGATTTAAACCGATGGTGGAAACTTCTCCGCGGGAAAGAAGATCCTTATTTGCAAGTAGGGCAATTTAATGACCGAAGTG
TTGCTAGTGATAGCGAATACGTATGGTCGTTAAAAAATGTTAGTTTTGATGTAAAACGTGGAGATGTTGTTGGCATTATC
GGTAAGAATGGTGCTGGAAAATCGACTCTTTTGAAAATATTATCCCAGGTCACTTCGCCTACACAGGGTAGTGTTAAAAT
TAAAGGTCGTGTTGCTGCATTGTTAGAAGTTGGAACTGGATTTCATCCTGACCTTACAGGTCGCGAGAATGTGTTTCTGA
ATGGGGCTATACTTGGAATGACCTCGGCAGAGATTAAAAGTAAATTTGATGAAATCATAAACTTTAGCGGAGTTGAAAAA
TACATAGATACTCCTGTAAAAAGATATTCTTCTGGAATGATGGTTCGTTTGGGATTTGCTGTTGCAGCACATTTGGAGCC
GGAGATTTTGATTGTTGATGAAGTGTTGGCTGTCGGTGATGCCGAGTTTCAAAAGAAATGTTTAGGTAAAATCCAAAATG
TTTCCAGCGAAGGAAGAACAGTTCTTTTTGTTAGTCACAATATGCAAGCACTTCAAGCAATTTGTAAACGAGGCATTTTG
CTAAAACATGGAATGGTCGAAGAAAATAGTGATATTGATGTTTGCATTCAAAAATACACTGGTCTCTTTCAAGAAGCAAA
TTTAGAAAATTTAGCAATTAATGATCGATTGGGTCGCACGAATAGCAATGGAAATGCTTTGTTTACGAGTGTGAGTCCTC
GAACGGGAAACCAACATTCTTGGAGCTTTGATTCAAAAGTTGATGTTTATTTAGATTTTACTTTAAATATTCGGGAACAT
TGTGATGGACTATCATTTTATTTTGCATTAATCGAACCTCTGGCAATGAGTGTGATTACAAATTATAAAACATGTATGAC
AGAACATTCTCCAAAGGTTGGGGAGCCATTCCATTTTTCCTTAAAGATTCCTAAAAATTCTCTTCGTGTTGGACAATATT
TAATGTACATTGCAATTGGAGATAAGGATCTAAGGAAATGGTATGACGTCATTGATAATAACATAAATTTACCAGCGCTT
AGTATCACTTCTTCCGAACTGGATCCACATCACAATATGGGTTTAGTGAGTCTCCCATTTGAATTGAAGATAGAAAAATA
A

Upstream 100 bases:

>100_bases
GTCGTTTTAGTTTTTCTTTCAATAATCATTTTCAATCGAGTTGAGAGATCATTTATCGATACTGTTTAGAGTCAGTGTTG
AGTTTTAGGAAACAAAATTC

Downstream 100 bases:

>100_bases
CTAATTTATTCTGCTAAAGGTGTTAATTTGTTTTTAATTAAAAGAATAGTAAATAAACTTCAAAGTGAAAACTACTTTCG
TTCTTATTCCCAAGAAGGAG

Product: ABC transporter ATP binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MSDVVLRIDNISKQYRLGQISTGSLAHDLNRWWKLLRGKEDPYLQVGQFNDRSVASDSEYVWSLKNVSFDVKRGDVVGII
GKNGAGKSTLLKILSQVTSPTQGSVKIKGRVAALLEVGTGFHPDLTGRENVFLNGAILGMTSAEIKSKFDEIINFSGVEK
YIDTPVKRYSSGMMVRLGFAVAAHLEPEILIVDEVLAVGDAEFQKKCLGKIQNVSSEGRTVLFVSHNMQALQAICKRGIL
LKHGMVEENSDIDVCIQKYTGLFQEANLENLAINDRLGRTNSNGNALFTSVSPRTGNQHSWSFDSKVDVYLDFTLNIREH
CDGLSFYFALIEPLAMSVITNYKTCMTEHSPKVGEPFHFSLKIPKNSLRVGQYLMYIAIGDKDLRKWYDVIDNNINLPAL
SITSSELDPHHNMGLVSLPFELKIEK

Sequences:

>Translated_426_residues
MSDVVLRIDNISKQYRLGQISTGSLAHDLNRWWKLLRGKEDPYLQVGQFNDRSVASDSEYVWSLKNVSFDVKRGDVVGII
GKNGAGKSTLLKILSQVTSPTQGSVKIKGRVAALLEVGTGFHPDLTGRENVFLNGAILGMTSAEIKSKFDEIINFSGVEK
YIDTPVKRYSSGMMVRLGFAVAAHLEPEILIVDEVLAVGDAEFQKKCLGKIQNVSSEGRTVLFVSHNMQALQAICKRGIL
LKHGMVEENSDIDVCIQKYTGLFQEANLENLAINDRLGRTNSNGNALFTSVSPRTGNQHSWSFDSKVDVYLDFTLNIREH
CDGLSFYFALIEPLAMSVITNYKTCMTEHSPKVGEPFHFSLKIPKNSLRVGQYLMYIAIGDKDLRKWYDVIDNNINLPAL
SITSSELDPHHNMGLVSLPFELKIEK
>Mature_425_residues
SDVVLRIDNISKQYRLGQISTGSLAHDLNRWWKLLRGKEDPYLQVGQFNDRSVASDSEYVWSLKNVSFDVKRGDVVGIIG
KNGAGKSTLLKILSQVTSPTQGSVKIKGRVAALLEVGTGFHPDLTGRENVFLNGAILGMTSAEIKSKFDEIINFSGVEKY
IDTPVKRYSSGMMVRLGFAVAAHLEPEILIVDEVLAVGDAEFQKKCLGKIQNVSSEGRTVLFVSHNMQALQAICKRGILL
KHGMVEENSDIDVCIQKYTGLFQEANLENLAINDRLGRTNSNGNALFTSVSPRTGNQHSWSFDSKVDVYLDFTLNIREHC
DGLSFYFALIEPLAMSVITNYKTCMTEHSPKVGEPFHFSLKIPKNSLRVGQYLMYIAIGDKDLRKWYDVIDNNINLPALS
ITSSELDPHHNMGLVSLPFELKIEK

Specific function: May form an ATP-driven O-antigen export apparatus, in association with RfbA [H]

COG id: COG1134

COG function: function code GM; ABC-type polysaccharide/polyol phosphate transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=186, Percent_Identity=28.494623655914, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI153792144, Length=196, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI6005701, Length=188, Percent_Identity=29.2553191489362, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI27477115, Length=217, Percent_Identity=27.6497695852535, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI27262624, Length=256, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI27262626, Length=256, Percent_Identity=25, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI105990541, Length=185, Percent_Identity=29.7297297297297, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI31657092, Length=197, Percent_Identity=28.4263959390863, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI150417984, Length=182, Percent_Identity=26.3736263736264, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI30795238, Length=197, Percent_Identity=24.8730964467005, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI45446740, Length=195, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI47078218, Length=195, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI27881501, Length=197, Percent_Identity=24.8730964467005, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI21536376, Length=193, Percent_Identity=26.9430051813472, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI116734710, Length=195, Percent_Identity=24.6153846153846, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI73747915, Length=212, Percent_Identity=27.8301886792453, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786398, Length=225, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786319, Length=209, Percent_Identity=25.3588516746411, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788761, Length=263, Percent_Identity=23.9543726235741, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788210, Length=221, Percent_Identity=30.7692307692308, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787029, Length=209, Percent_Identity=26.7942583732057, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081709, Length=194, Percent_Identity=24.7422680412371, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789032, Length=205, Percent_Identity=25.8536585365854, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1788897, Length=206, Percent_Identity=26.6990291262136, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1786703, Length=216, Percent_Identity=28.7037037037037, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788225, Length=207, Percent_Identity=26.5700483091787, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48995001, Length=200, Percent_Identity=25.5, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787089, Length=221, Percent_Identity=22.6244343891403, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082267, Length=233, Percent_Identity=22.7467811158798, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI48994943, Length=147, Percent_Identity=29.9319727891156, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787105, Length=214, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081834, Length=211, Percent_Identity=28.436018957346, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081782, Length=202, Percent_Identity=23.2673267326733, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1790525, Length=204, Percent_Identity=25.9803921568627, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87081791, Length=203, Percent_Identity=22.1674876847291, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1786653, Length=232, Percent_Identity=25.4310344827586, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787370, Length=238, Percent_Identity=19.7478991596639, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=199, Percent_Identity=26.6331658291457, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=193, Percent_Identity=25.3886010362694, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI115534520, Length=241, Percent_Identity=24.4813278008299, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71983523, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71983510, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=189, Percent_Identity=26.4550264550265, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24666092, Length=195, Percent_Identity=28.7179487179487, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007184, Length=185, Percent_Identity=25.9459459459459, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221500365, Length=185, Percent_Identity=25.9459459459459, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221512771, Length=191, Percent_Identity=26.1780104712042, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24643674, Length=194, Percent_Identity=23.7113402061856, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24648314, Length=184, Percent_Identity=27.7173913043478, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28573571, Length=193, Percent_Identity=23.3160621761658, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573573, Length=193, Percent_Identity=23.3160621761658, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24650853, Length=265, Percent_Identity=24.5283018867925, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363262, Length=218, Percent_Identity=27.5229357798165, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24650855, Length=265, Percent_Identity=24.5283018867925, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24653245, Length=218, Percent_Identity=27.5229357798165, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 47452; Mature: 47321

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDVVLRIDNISKQYRLGQISTGSLAHDLNRWWKLLRGKEDPYLQVGQFNDRSVASDSEY
CCCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHH
VWSLKNVSFDVKRGDVVGIIGKNGAGKSTLLKILSQVTSPTQGSVKIKGRVAALLEVGTG
EEEECCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECHHEEEEEECCCC
FHPDLTGRENVFLNGAILGMTSAEIKSKFDEIINFSGVEKYIDTPVKRYSSGMMVRLGFA
CCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCEEEEEEE
VAAHLEPEILIVDEVLAVGDAEFQKKCLGKIQNVSSEGRTVLFVSHNMQALQAICKRGIL
HEECCCCCEEEEEHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCEE
LKHGMVEENSDIDVCIQKYTGLFQEANLENLAINDRLGRTNSNGNALFTSVSPRTGNQHS
EECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCC
WSFDSKVDVYLDFTLNIREHCDGLSFYFALIEPLAMSVITNYKTCMTEHSPKVGEPFHFS
CCCCCEEEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LKIPKNSLRVGQYLMYIAIGDKDLRKWYDVIDNNINLPALSITSSELDPHHNMGLVSLPF
EECCCCHHCCCEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEECCE
ELKIEK
EEEECC
>Mature Secondary Structure 
SDVVLRIDNISKQYRLGQISTGSLAHDLNRWWKLLRGKEDPYLQVGQFNDRSVASDSEY
CCEEEEECCCCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHH
VWSLKNVSFDVKRGDVVGIIGKNGAGKSTLLKILSQVTSPTQGSVKIKGRVAALLEVGTG
EEEECCCEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCEEECHHEEEEEECCCC
FHPDLTGRENVFLNGAILGMTSAEIKSKFDEIINFSGVEKYIDTPVKRYSSGMMVRLGFA
CCCCCCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCHHHHHCCHHHHHCCCCEEEEEEE
VAAHLEPEILIVDEVLAVGDAEFQKKCLGKIQNVSSEGRTVLFVSHNMQALQAICKRGIL
HEECCCCCEEEEEHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHCCEE
LKHGMVEENSDIDVCIQKYTGLFQEANLENLAINDRLGRTNSNGNALFTSVSPRTGNQHS
EECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCC
WSFDSKVDVYLDFTLNIREHCDGLSFYFALIEPLAMSVITNYKTCMTEHSPKVGEPFHFS
CCCCCEEEEEEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEE
LKIPKNSLRVGQYLMYIAIGDKDLRKWYDVIDNNINLPALSITSSELDPHHNMGLVSLPF
EECCCCHHCCCEEEEEEEECCHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCEEECCE
ELKIEK
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8626291 [H]