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The map label for this gene is tldD [C]

Identifier: 183221094

GI number: 183221094

Start: 1781064

End: 1782449

Strand: Direct

Name: tldD [C]

Synonym: LEPBI_I1708

Alternate gene names: 183221094

Gene position: 1781064-1782449 (Clockwise)

Preceding gene: 183221093

Following gene: 183221095

Centisome position: 49.48

GC content: 44.3

Gene sequence:

>1386_bases
ATGCGTGACCTATTAAAAGAATGTTTATCCGAAGAATCTGGATTCGTAGAATTACGTTATCACCATAAAGAAAGTCGTTC
CTTTTTTGCGGAACGAGGTCGAGTAGAATCCACTGCCCTACGGAAACGAACTGGTGTTGGTGTCAGGGTTCTCGAATCGG
GTACTTGGGGTTTTGCATCCACTAGCGAAATTTCGAAAGCCTCCATCCAAAATGCCATTCAAATCGCCAAAAAAGCAGCA
CGGCTATCTTCTGCTCTTAGAAAAGAGAAAATCCCAAATCTACCGAAGGCAAATTTTGCGATCGGAGATTTTATCGGCAA
AGGGATCGAAGACTTTCGTGGTCGGTCTGTAGAAGAAAAATTAAAAATGGTTCTCGACATTCAAAACGAAGCTGTAAAAC
AATCCACCAAACTGCAGTCAGTTGGTTGTGGGTATTCTGAAATTTATGAAGAAAAAGCCATTGTCACGACAGATGGTGCT
GATAGTTTTTTTAGTTTGGTACGACCAGAATTTCGAGTCTCTGCCGTCGCAAAAGATGATGGGAAACTGGAATCAGGCTC
GCATTCCATTGGTGTGACGGGTGGTTGGGACTGTCTCTTTCGTTCCCAATCTGCCACGGAAATTTCAGAAGAAGCATGTA
AAACCGCAGTCGATTTGTTAACTAGCGAACTTCCCGATGGTGGTCTTTCTACTGTCATCCTTTCGCCATCGATTGTGGGA
CTTCTTGTCCATGAAGCCATTGGGCATACTGTGGAAGCTGATTTTGTGTTATCAGGCTCTGTGGCCCAAGGCAAAATTGG
CCACCGTGTTGGATCCGACTTGGTTACGTTATGCGACTCAGGTAATTCTGAGTTTTATGAAGGAGCTGGAGGAACCATTC
CTGTGGACGATGAGGGGATCATTCCTACCAATACTGTCATCATTAAAAATGGAATCCTAACATCCTACCTTCATAATCGA
GAGACTGCGGAACGATTTGGTGTGGCTCCAACGGGATCTGCAAGGGCCTGGGAGTATGGGGACGTCCCATTGATTCGGAT
GCGTAATACCTTTTTGTTACCAGGAAATTCCAGTTTAGAAGAAATGATCGCTAGTACCAAAGATGGGTATTATTTAGATG
GTGCCAAAAACGGCCAAGCAGATGCCACAGGTGAGTTTATGTTTGCCGTTCAAAAAGCCTATCGCATTCAAAATGGGAAG
GTCACTCATTTGTTAAAAGGTGTGACCGTTTCAGGACTTGCGTTTGATGTCTTACAAAATGTAGATATGGTGTCGAAAGA
ATTTAAGTGGGATTTAGGTTCGGGCCACTGCGGGAAAGGCCAACCTGCGAAAGTAGATGCCGGTGGACCATATGTTCGAA
CTAAAGTGTTGTTAGGTGGTAAATGA

Upstream 100 bases:

>100_bases
AAGGCAGATGGTTACCCAGGATCCTACTTGATTTTTTTGATTCCAAGATCAAATCCTAACCCTAAAAAATACCAAGGAAC
GAAACGAAGGACGGTGTACA

Downstream 100 bases:

>100_bases
TGGATCGTGGTGCGATAGAAAAACGATTGAATCACCAAAAAGATTTACTTTCGAATTTAGTAAAGAAAGCCAAGTCAAAT
GGAATGGATCAAGTAGAGAT

Product: putative protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MRDLLKECLSEESGFVELRYHHKESRSFFAERGRVESTALRKRTGVGVRVLESGTWGFASTSEISKASIQNAIQIAKKAA
RLSSALRKEKIPNLPKANFAIGDFIGKGIEDFRGRSVEEKLKMVLDIQNEAVKQSTKLQSVGCGYSEIYEEKAIVTTDGA
DSFFSLVRPEFRVSAVAKDDGKLESGSHSIGVTGGWDCLFRSQSATEISEEACKTAVDLLTSELPDGGLSTVILSPSIVG
LLVHEAIGHTVEADFVLSGSVAQGKIGHRVGSDLVTLCDSGNSEFYEGAGGTIPVDDEGIIPTNTVIIKNGILTSYLHNR
ETAERFGVAPTGSARAWEYGDVPLIRMRNTFLLPGNSSLEEMIASTKDGYYLDGAKNGQADATGEFMFAVQKAYRIQNGK
VTHLLKGVTVSGLAFDVLQNVDMVSKEFKWDLGSGHCGKGQPAKVDAGGPYVRTKVLLGGK

Sequences:

>Translated_461_residues
MRDLLKECLSEESGFVELRYHHKESRSFFAERGRVESTALRKRTGVGVRVLESGTWGFASTSEISKASIQNAIQIAKKAA
RLSSALRKEKIPNLPKANFAIGDFIGKGIEDFRGRSVEEKLKMVLDIQNEAVKQSTKLQSVGCGYSEIYEEKAIVTTDGA
DSFFSLVRPEFRVSAVAKDDGKLESGSHSIGVTGGWDCLFRSQSATEISEEACKTAVDLLTSELPDGGLSTVILSPSIVG
LLVHEAIGHTVEADFVLSGSVAQGKIGHRVGSDLVTLCDSGNSEFYEGAGGTIPVDDEGIIPTNTVIIKNGILTSYLHNR
ETAERFGVAPTGSARAWEYGDVPLIRMRNTFLLPGNSSLEEMIASTKDGYYLDGAKNGQADATGEFMFAVQKAYRIQNGK
VTHLLKGVTVSGLAFDVLQNVDMVSKEFKWDLGSGHCGKGQPAKVDAGGPYVRTKVLLGGK
>Mature_461_residues
MRDLLKECLSEESGFVELRYHHKESRSFFAERGRVESTALRKRTGVGVRVLESGTWGFASTSEISKASIQNAIQIAKKAA
RLSSALRKEKIPNLPKANFAIGDFIGKGIEDFRGRSVEEKLKMVLDIQNEAVKQSTKLQSVGCGYSEIYEEKAIVTTDGA
DSFFSLVRPEFRVSAVAKDDGKLESGSHSIGVTGGWDCLFRSQSATEISEEACKTAVDLLTSELPDGGLSTVILSPSIVG
LLVHEAIGHTVEADFVLSGSVAQGKIGHRVGSDLVTLCDSGNSEFYEGAGGTIPVDDEGIIPTNTVIIKNGILTSYLHNR
ETAERFGVAPTGSARAWEYGDVPLIRMRNTFLLPGNSSLEEMIASTKDGYYLDGAKNGQADATGEFMFAVQKAYRIQNGK
VTHLLKGVTVSGLAFDVLQNVDMVSKEFKWDLGSGHCGKGQPAKVDAGGPYVRTKVLLGGK

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=452, Percent_Identity=31.1946902654867, Blast_Score=195, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 49643; Mature: 49643

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDLLKECLSEESGFVELRYHHKESRSFFAERGRVESTALRKRTGVGVRVLESGTWGFAS
CHHHHHHHHCCCCCEEEEEEECHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCC
TSEISKASIQNAIQIAKKAARLSSALRKEKIPNLPKANFAIGDFIGKGIEDFRGRSVEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHCCCCHHHH
LKMVLDIQNEAVKQSTKLQSVGCGYSEIYEEKAIVTTDGADSFFSLVRPEFRVSAVAKDD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCHHHHHHHHCCCCEEEEEECCC
GKLESGSHSIGVTGGWDCLFRSQSATEISEEACKTAVDLLTSELPDGGLSTVILSPSIVG
CCCCCCCCEECCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHH
LLVHEAIGHTVEADFVLSGSVAQGKIGHRVGSDLVTLCDSGNSEFYEGAGGTIPVDDEGI
HHHHHHHCCCEEECEEEECCCCCCCHHHHHCHHHHHHHCCCCCCEECCCCCCCCCCCCCC
IPTNTVIIKNGILTSYLHNRETAERFGVAPTGSARAWEYGDVPLIRMRNTFLLPGNSSLE
CCCCEEEEECCHHHHHHHCHHHHHHHCCCCCCCCCCEECCCCCEEEECCEEEECCCCHHH
EMIASTKDGYYLDGAKNGQADATGEFMFAVQKAYRIQNGKVTHLLKGVTVSGLAFDVLQN
HHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHHH
VDMVSKEFKWDLGSGHCGKGQPAKVDAGGPYVRTKVLLGGK
HHHHHHHHCCCCCCCCCCCCCCCEECCCCCEEEEEEEECCC
>Mature Secondary Structure
MRDLLKECLSEESGFVELRYHHKESRSFFAERGRVESTALRKRTGVGVRVLESGTWGFAS
CHHHHHHHHCCCCCEEEEEEECHHHHHHHHHCCCCHHHHHHHHCCCCEEEEECCCCCCCC
TSEISKASIQNAIQIAKKAARLSSALRKEKIPNLPKANFAIGDFIGKGIEDFRGRSVEEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHCCCCHHHH
LKMVLDIQNEAVKQSTKLQSVGCGYSEIYEEKAIVTTDGADSFFSLVRPEFRVSAVAKDD
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCEEEECCHHHHHHHHCCCCEEEEEECCC
GKLESGSHSIGVTGGWDCLFRSQSATEISEEACKTAVDLLTSELPDGGLSTVILSPSIVG
CCCCCCCCEECCCCCHHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHH
LLVHEAIGHTVEADFVLSGSVAQGKIGHRVGSDLVTLCDSGNSEFYEGAGGTIPVDDEGI
HHHHHHHCCCEEECEEEECCCCCCCHHHHHCHHHHHHHCCCCCCEECCCCCCCCCCCCCC
IPTNTVIIKNGILTSYLHNRETAERFGVAPTGSARAWEYGDVPLIRMRNTFLLPGNSSLE
CCCCEEEEECCHHHHHHHCHHHHHHHCCCCCCCCCCEECCCCCEEEECCEEEECCCCHHH
EMIASTKDGYYLDGAKNGQADATGEFMFAVQKAYRIQNGKVTHLLKGVTVSGLAFDVLQN
HHHHCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEHHHCCCCHHHHHHHHHHH
VDMVSKEFKWDLGSGHCGKGQPAKVDAGGPYVRTKVLLGGK
HHHHHHHHCCCCCCCCCCCCCCCEECCCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]