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The map label for this gene is tal

Identifier: 183220853

GI number: 183220853

Start: 1527745

End: 1528389

Strand: Reverse

Name: tal

Synonym: LEPBI_I1466

Alternate gene names: 183220853

Gene position: 1528389-1527745 (Counterclockwise)

Preceding gene: 183220854

Following gene: 183220849

Centisome position: 42.46

GC content: 41.86

Gene sequence:

>645_bases
ATGAATTTATTTTTAGACACAGCCAACATTGACGAAATCAAAAAAGTCCATGAATTAGGCTTACTTGACGGTATCACGAC
AAACCCTTCCATCATTGCAAAATCAGGCCGAAAATTCACAGAAGTCATCAAAGAAATCTGTAGTTTTGTAAAAGGTCCTG
TAAGTGCCGAGGTACTTGCGACCGATGCGCCGACCATGATCAAAGAAGGATTAGAACTTTCTAAAATTGCAGAAAACGTT
GTAGTCAAAGTCCCTCTCATCCCTGAAGGCATGAAAGCAGTGAAAGCATTTGCAGAACAAGGGATCCAAACAAACGTTAC
ACTTTGTTTCACAGCAAACCAAGCCTTACTTGCAGCAAAAGCTGGTGCAACCTTTATCTCTCCCTTCGTAGGACGATTGG
ATGATGTGGGATACGATGGTTTGGAACTCATTTCTGAGATCCGAGAAATTTACGACAACTACGGAATTGAAACTCAAATC
CTTGCGGCATCTGTTCGCCACCCCATTCACTTCAAAGAAGTGGCATTACGCGGAGCGGATTGTGTGACACTTCCTTATTC
GGTATTTGAAATGTTATTCAAACACCCACTCACAGACAGTGGACTTGCTAAGTTTGTCGAAGACTCCAAAAAACTAAACT
GGTAA

Upstream 100 bases:

>100_bases
TTTCTTCAGTGTTCAGGAAACAAAAACCTTGCGGGATTTAATCCCGTAGTTACCTTGTCTCGTGAGGCTTGGTTCTAAAT
CACCAAGCATACGAGGCAAA

Downstream 100 bases:

>100_bases
AACCTAAAACCACACCACCGGATACTTCCGGTGGTGTACCAGATTGTTCACGACTAACGCATTACAAAGTAATACAAGAA
CACCTACCATAACGGGAAAA

Product: putative translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MNLFLDTANIDEIKKVHELGLLDGITTNPSIIAKSGRKFTEVIKEICSFVKGPVSAEVLATDAPTMIKEGLELSKIAENV
VVKVPLIPEGMKAVKAFAEQGIQTNVTLCFTANQALLAAKAGATFISPFVGRLDDVGYDGLELISEIREIYDNYGIETQI
LAASVRHPIHFKEVALRGADCVTLPYSVFEMLFKHPLTDSGLAKFVEDSKKLNW

Sequences:

>Translated_214_residues
MNLFLDTANIDEIKKVHELGLLDGITTNPSIIAKSGRKFTEVIKEICSFVKGPVSAEVLATDAPTMIKEGLELSKIAENV
VVKVPLIPEGMKAVKAFAEQGIQTNVTLCFTANQALLAAKAGATFISPFVGRLDDVGYDGLELISEIREIYDNYGIETQI
LAASVRHPIHFKEVALRGADCVTLPYSVFEMLFKHPLTDSGLAKFVEDSKKLNW
>Mature_214_residues
MNLFLDTANIDEIKKVHELGLLDGITTNPSIIAKSGRKFTEVIKEICSFVKGPVSAEVLATDAPTMIKEGLELSKIAENV
VVKVPLIPEGMKAVKAFAEQGIQTNVTLCFTANQALLAAKAGATFISPFVGRLDDVGYDGLELISEIREIYDNYGIETQI
LAASVRHPIHFKEVALRGADCVTLPYSVFEMLFKHPLTDSGLAKFVEDSKKLNW

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=173, Percent_Identity=33.5260115606936, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI87081788, Length=210, Percent_Identity=33.8095238095238, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI1790382, Length=210, Percent_Identity=34.7619047619048, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786189, Length=171, Percent_Identity=30.4093567251462, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788807, Length=196, Percent_Identity=28.0612244897959, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI25153750, Length=180, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6321480, Length=200, Percent_Identity=32, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549185, Length=172, Percent_Identity=30.2325581395349, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_LEPBA (B0SGW0)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001962505.1
- ProteinModelPortal:   B0SGW0
- SMR:   B0SGW0
- GeneID:   6387186
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_1413
- HOGENOM:   HBG533000
- OMA:   IHKNIVI
- ProtClustDB:   PRK01362
- BioCyc:   LBIF355278:LBF_1413-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23382; Mature: 23382

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLFLDTANIDEIKKVHELGLLDGITTNPSIIAKSGRKFTEVIKEICSFVKGPVSAEVLA
CCEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEE
TDAPTMIKEGLELSKIAENVVVKVPLIPEGMKAVKAFAEQGIQTNVTLCFTANQALLAAK
CCCHHHHHHCCHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
AGATFISPFVGRLDDVGYDGLELISEIREIYDNYGIETQILAASVRHPIHFKEVALRGAD
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHCCCC
CVTLPYSVFEMLFKHPLTDSGLAKFVEDSKKLNW
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLFLDTANIDEIKKVHELGLLDGITTNPSIIAKSGRKFTEVIKEICSFVKGPVSAEVLA
CCEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEE
TDAPTMIKEGLELSKIAENVVVKVPLIPEGMKAVKAFAEQGIQTNVTLCFTANQALLAAK
CCCHHHHHHCCHHHHHHHHHEEECCCCCHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHH
AGATFISPFVGRLDDVGYDGLELISEIREIYDNYGIETQILAASVRHPIHFKEVALRGAD
CCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHCCCC
CVTLPYSVFEMLFKHPLTDSGLAKFVEDSKKLNW
EEECCHHHHHHHHHCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA