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The map label for this gene is ydcR [H]

Identifier: 183220841

GI number: 183220841

Start: 1515789

End: 1517216

Strand: Reverse

Name: ydcR [H]

Synonym: LEPBI_I1453

Alternate gene names: 183220841

Gene position: 1517216-1515789 (Counterclockwise)

Preceding gene: 183220845

Following gene: 183220840

Centisome position: 42.15

GC content: 36.13

Gene sequence:

>1428_bases
ATGAATCTCACTATAGGTATACAGATGGAAAAAACAAAATACCAACAACTTGCATCTGATCTCAAAAAAGAAATTGAATC
CGGATATTATTCTGAAAACGAAAAGATCCCATCTCTTCGCGAAATCCAATCTTTAAAATCATGTAGTTTATCAACAGCCA
AAGAAGCCTACCGAATTTTGGAAGAAGAAGGTTATCTTTATGCTCAAAACAAATCAGGCTATTATGTACAGAAACAAATC
AGTTCGGTGATCTTTGGTCCTCAAAATCAATTTTATGAATCGGTAGAAGCCGATGATCGAATCCAACAAATCATGAATAC
TGTCATGGATCCAAAACTTTTATCCTTTGGAGCCGCTATCCCATCTGAAACGTATTTACCTATTCAGGAATTGAATACTG
CATTCAAAAGAGCATTTTTACACAAAGATATCTTTAGTTATGGGGACTTACAAGGGAATCCAAATTTACGAGAATGGATC
GCCAAACGAACATCCCTTTTTGGATACCGAGTGATTTCTAAACAAATCCAAATCACTTCAGGTTGCACAGAAGCAATCAC
CTACTCTTTGTTTGCTGTGACTGAACCTGGCGATACCGTGATTGTTCCTTCTCCCATTTATGTAGGGCTCTTCCAAATCC
TAGAAACACTAAAATTAAAAGTAGTAGAAATTCCTTATAGAAGTGGTGAAGGAATAAATAGTACCGAATTTGAAAAACTC
ATCAAACGACACAAACCAAAGGTATTTTTATTTGCCGCAAACTTCAATAACCCCAATGGAATTTTATTTAGTGACCAAAC
AAAACAAAACTTAGCGAATATCTCCTACCAATACGGAATCCATCTCGTAGAAGATGATATTTATGGGGATTTGTACTTTG
ATGGGAGTCGACCAAAACCCTTGGTGAGTTTTTTCCCAGAAGGAAAGAATGGTCCGAGATCATTTTTATGTTCTTCCTTT
TCCAAAACACTTTCACCTGGATTACGGATTGGTTGGGTCTCTTCCAAAACGGGGATTTCTGCCTTATCCAAAATTTCGAG
AGCATTTAAAATCGCAGAAAACCATCCGACTCAAATATGTATTTTGGAATTTTTAAAACGCCAAACATACGAAAGGCATT
TAAAATATTTACGACGAGAATACAAATCACTTTGCCAGGACTATATCCAATTACTTGTCAAAGAAAGTGAAGGAAACATA
AAAATCACAAAACCAGACGGTGGTTTTGTCCTATGGATTGAATCAGCGTTAGATGGTGATAAATTACTTTTGGATGCAAA
AAAAATGGGCATAGCGATTGCACCAGGATCCTTATTTGGACTTTCTAAACATTGGAACCAATTCTTTCGTTTGAATGTTT
CCGTAGGAAGCTCACCTAAAATCAGGGAGAAACTCAGTTTGTTTGCAAAACGATTCTTAAAAAAATAG

Upstream 100 bases:

>100_bases
AGGAACGAATGTGTTTCGTTCTTTTTGCCAAAAATAGATTTGTCAGATTAGATTCCATGTATATAAATTATCAATCAAAT
GGACATCTGTCCATATACAG

Downstream 100 bases:

>100_bases
AATTTCAAAACTAACTTTTTAGTTGCTGTCAAACCAAACCTTGAACACCGTTAGGATATGTCTGACACCACTCGCAAGTA
TTTGGAAACATCCCAAATCA

Product: putative bifunctional protein: transcriptional regulator/amino transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 475; Mature: 475

Protein sequence:

>475_residues
MNLTIGIQMEKTKYQQLASDLKKEIESGYYSENEKIPSLREIQSLKSCSLSTAKEAYRILEEEGYLYAQNKSGYYVQKQI
SSVIFGPQNQFYESVEADDRIQQIMNTVMDPKLLSFGAAIPSETYLPIQELNTAFKRAFLHKDIFSYGDLQGNPNLREWI
AKRTSLFGYRVISKQIQITSGCTEAITYSLFAVTEPGDTVIVPSPIYVGLFQILETLKLKVVEIPYRSGEGINSTEFEKL
IKRHKPKVFLFAANFNNPNGILFSDQTKQNLANISYQYGIHLVEDDIYGDLYFDGSRPKPLVSFFPEGKNGPRSFLCSSF
SKTLSPGLRIGWVSSKTGISALSKISRAFKIAENHPTQICILEFLKRQTYERHLKYLRREYKSLCQDYIQLLVKESEGNI
KITKPDGGFVLWIESALDGDKLLLDAKKMGIAIAPGSLFGLSKHWNQFFRLNVSVGSSPKIREKLSLFAKRFLKK

Sequences:

>Translated_475_residues
MNLTIGIQMEKTKYQQLASDLKKEIESGYYSENEKIPSLREIQSLKSCSLSTAKEAYRILEEEGYLYAQNKSGYYVQKQI
SSVIFGPQNQFYESVEADDRIQQIMNTVMDPKLLSFGAAIPSETYLPIQELNTAFKRAFLHKDIFSYGDLQGNPNLREWI
AKRTSLFGYRVISKQIQITSGCTEAITYSLFAVTEPGDTVIVPSPIYVGLFQILETLKLKVVEIPYRSGEGINSTEFEKL
IKRHKPKVFLFAANFNNPNGILFSDQTKQNLANISYQYGIHLVEDDIYGDLYFDGSRPKPLVSFFPEGKNGPRSFLCSSF
SKTLSPGLRIGWVSSKTGISALSKISRAFKIAENHPTQICILEFLKRQTYERHLKYLRREYKSLCQDYIQLLVKESEGNI
KITKPDGGFVLWIESALDGDKLLLDAKKMGIAIAPGSLFGLSKHWNQFFRLNVSVGSSPKIREKLSLFAKRFLKK
>Mature_475_residues
MNLTIGIQMEKTKYQQLASDLKKEIESGYYSENEKIPSLREIQSLKSCSLSTAKEAYRILEEEGYLYAQNKSGYYVQKQI
SSVIFGPQNQFYESVEADDRIQQIMNTVMDPKLLSFGAAIPSETYLPIQELNTAFKRAFLHKDIFSYGDLQGNPNLREWI
AKRTSLFGYRVISKQIQITSGCTEAITYSLFAVTEPGDTVIVPSPIYVGLFQILETLKLKVVEIPYRSGEGINSTEFEKL
IKRHKPKVFLFAANFNNPNGILFSDQTKQNLANISYQYGIHLVEDDIYGDLYFDGSRPKPLVSFFPEGKNGPRSFLCSSF
SKTLSPGLRIGWVSSKTGISALSKISRAFKIAENHPTQICILEFLKRQTYERHLKYLRREYKSLCQDYIQLLVKESEGNI
KITKPDGGFVLWIESALDGDKLLLDAKKMGIAIAPGSLFGLSKHWNQFFRLNVSVGSSPKIREKLSLFAKRFLKK

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=282, Percent_Identity=25.886524822695, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI33469970, Length=282, Percent_Identity=25.886524822695, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI4507369, Length=208, Percent_Identity=27.4038461538462, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1787710, Length=450, Percent_Identity=34.2222222222222, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1790797, Length=461, Percent_Identity=30.8026030368764, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1788722, Length=344, Percent_Identity=23.546511627907, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=308, Percent_Identity=24.3506493506494, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=282, Percent_Identity=25.886524822695, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321000, Length=268, Percent_Identity=25.7462686567164, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=284, Percent_Identity=23.5915492957746, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54002; Mature: 54002

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTIGIQMEKTKYQQLASDLKKEIESGYYSENEKIPSLREIQSLKSCSLSTAKEAYRIL
CCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
EEEGYLYAQNKSGYYVQKQISSVIFGPQNQFYESVEADDRIQQIMNTVMDPKLLSFGAAI
HHCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCC
PSETYLPIQELNTAFKRAFLHKDIFSYGDLQGNPNLREWIAKRTSLFGYRVISKQIQITS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECC
GCTEAITYSLFAVTEPGDTVIVPSPIYVGLFQILETLKLKVVEIPYRSGEGINSTEFEKL
CHHHHHEEEEEEEECCCCEEEECCHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHH
IKRHKPKVFLFAANFNNPNGILFSDQTKQNLANISYQYGIHLVEDDIYGDLYFDGSRPKP
HHHCCCCEEEEEEECCCCCCEEECCHHHHHHHHCCHHHCCEEEECCCEEEEEECCCCCCC
LVSFFPEGKNGPRSFLCSSFSKTLSPGLRIGWVSSKTGISALSKISRAFKIAENHPTQIC
HHEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
ILEFLKRQTYERHLKYLRREYKSLCQDYIQLLVKESEGNIKITKPDGGFVLWIESALDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCC
KLLLDAKKMGIAIAPGSLFGLSKHWNQFFRLNVSVGSSPKIREKLSLFAKRFLKK
CEEEEHHHCCEEECCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNLTIGIQMEKTKYQQLASDLKKEIESGYYSENEKIPSLREIQSLKSCSLSTAKEAYRIL
CCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
EEEGYLYAQNKSGYYVQKQISSVIFGPQNQFYESVEADDRIQQIMNTVMDPKLLSFGAAI
HHCCEEEEECCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCC
PSETYLPIQELNTAFKRAFLHKDIFSYGDLQGNPNLREWIAKRTSLFGYRVISKQIQITS
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECC
GCTEAITYSLFAVTEPGDTVIVPSPIYVGLFQILETLKLKVVEIPYRSGEGINSTEFEKL
CHHHHHEEEEEEEECCCCEEEECCHHHHHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHH
IKRHKPKVFLFAANFNNPNGILFSDQTKQNLANISYQYGIHLVEDDIYGDLYFDGSRPKP
HHHCCCCEEEEEEECCCCCCEEECCHHHHHHHHCCHHHCCEEEECCCEEEEEECCCCCCC
LVSFFPEGKNGPRSFLCSSFSKTLSPGLRIGWVSSKTGISALSKISRAFKIAENHPTQIC
HHEECCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHH
ILEFLKRQTYERHLKYLRREYKSLCQDYIQLLVKESEGNIKITKPDGGFVLWIESALDGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEEECCCCCC
KLLLDAKKMGIAIAPGSLFGLSKHWNQFFRLNVSVGSSPKIREKLSLFAKRFLKK
CEEEEHHHCCEEECCCHHHHHHHHCCEEEEEEEECCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]