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The map label for this gene is gcp [H]

Identifier: 183220709

GI number: 183220709

Start: 1375238

End: 1376263

Strand: Direct

Name: gcp [H]

Synonym: LEPBI_I1319

Alternate gene names: 183220709

Gene position: 1375238-1376263 (Clockwise)

Preceding gene: 183220708

Following gene: 183220710

Centisome position: 38.2

GC content: 40.84

Gene sequence:

>1026_bases
ATGGTCTACGGATTAGGCATTGAATCCAGTTGCGATGAAACATCCATTGCCATTGTTAGAGATGGCAATGAAGTTGTATC
ATTAAAAGTGTATAGCCAAATTGAAACCCATTCCCCTTACAGGGGGGTGGTTCCAGAAATTGCCTCACGTGCCCATTTGG
AAAAAATCAATTCTCTTCTTGCTGTTTGTATGGAAGAAGCAAAGATCCAATTTTTGGAACTCAAATACATTGCAGTTACG
GGATACCCAGGGCTTGTAGGTTCACTGATGATTGGTGCACAATTGGCTAGATGTATCTCACTTGTACACTCCATTCCCAT
TGTTCTCGTGAACCACTTGGAAGCGCACCTAACTGTGATAGGACTCGAAAATGAATTGCCCGCATTTCCTTGGTTAGGCG
TTCTTTTGTCTGGGGGAAACTCTTCGATTTATATTTACAAAGGATTTGGAGATTTGCAGTTACTTGCAGACACAAATGAT
GATTCTTTAGGGGAAGCATTTGATAAAGTCAGCGCTGTCCTAGGTTTACCGTATCCGGGAGGTCCCTACATTGAAAAAGA
AGCTTTGGAGTACAAACGACCAAAGGGAGAGAAAAACCCATTTCCCAAATTACTCAAAGAGGATGGGCCAGAAAAAATCC
GATTTTCGTATAGTGGTTTAAAAACTGCCGTTCTTTATTACTTAAAATCCCTAACAGAACCACCTCCCATTCAGAAAATC
TCCTTTTACTTTCAACAAACTGCCTTTGAGCTCGTTGTCCGAAATATCAAAAAGGCGATTCAAAAAACCAATATCAAAAC
AGTCGTGGCCGCTGGGGGAGTGCTTGCCAACGAAACACTTCGATCTGTACTTTTGGCTGAATCGAAAACTGCTCCTTTCC
AACTGTATTACCCGCAAAAAAAAATTTACTGCACAGATAACGGAGCGATGGTGGCATGTCTTGGATACCATCTTTGGAAA
GAAAAAAAATTTGTAGGACTCGATTTTAAAGTGAGTCCGAAACGAAACTTTGAACAAATAATATGA

Upstream 100 bases:

>100_bases
GATTTTTTTATTCAATGAAATGAGAATGGGTACTTCCCAAACCAAACCTAGACTAGATTTGGACATCCAGTTATCCGAGG
CTATCAACCTCTTAAAATAA

Downstream 100 bases:

>100_bases
AACTAAAATTAACTTGGATCCCGAACACATTAACACTTGGAAACCTCACTTTAGGGTTTGTTTCCATGCTCCTTGTTGCA
GAAACAAATCCTTCCCAACC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MVYGLGIESSCDETSIAIVRDGNEVVSLKVYSQIETHSPYRGVVPEIASRAHLEKINSLLAVCMEEAKIQFLELKYIAVT
GYPGLVGSLMIGAQLARCISLVHSIPIVLVNHLEAHLTVIGLENELPAFPWLGVLLSGGNSSIYIYKGFGDLQLLADTND
DSLGEAFDKVSAVLGLPYPGGPYIEKEALEYKRPKGEKNPFPKLLKEDGPEKIRFSYSGLKTAVLYYLKSLTEPPPIQKI
SFYFQQTAFELVVRNIKKAIQKTNIKTVVAAGGVLANETLRSVLLAESKTAPFQLYYPQKKIYCTDNGAMVACLGYHLWK
EKKFVGLDFKVSPKRNFEQII

Sequences:

>Translated_341_residues
MVYGLGIESSCDETSIAIVRDGNEVVSLKVYSQIETHSPYRGVVPEIASRAHLEKINSLLAVCMEEAKIQFLELKYIAVT
GYPGLVGSLMIGAQLARCISLVHSIPIVLVNHLEAHLTVIGLENELPAFPWLGVLLSGGNSSIYIYKGFGDLQLLADTND
DSLGEAFDKVSAVLGLPYPGGPYIEKEALEYKRPKGEKNPFPKLLKEDGPEKIRFSYSGLKTAVLYYLKSLTEPPPIQKI
SFYFQQTAFELVVRNIKKAIQKTNIKTVVAAGGVLANETLRSVLLAESKTAPFQLYYPQKKIYCTDNGAMVACLGYHLWK
EKKFVGLDFKVSPKRNFEQII
>Mature_341_residues
MVYGLGIESSCDETSIAIVRDGNEVVSLKVYSQIETHSPYRGVVPEIASRAHLEKINSLLAVCMEEAKIQFLELKYIAVT
GYPGLVGSLMIGAQLARCISLVHSIPIVLVNHLEAHLTVIGLENELPAFPWLGVLLSGGNSSIYIYKGFGDLQLLADTND
DSLGEAFDKVSAVLGLPYPGGPYIEKEALEYKRPKGEKNPFPKLLKEDGPEKIRFSYSGLKTAVLYYLKSLTEPPPIQKI
SFYFQQTAFELVVRNIKKAIQKTNIKTVVAAGGVLANETLRSVLLAESKTAPFQLYYPQKKIYCTDNGAMVACLGYHLWK
EKKFVGLDFKVSPKRNFEQII

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=329, Percent_Identity=29.1793313069909, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI8923380, Length=329, Percent_Identity=23.1003039513678, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1789445, Length=331, Percent_Identity=36.8580060422961, Blast_Score=219, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17557464, Length=171, Percent_Identity=33.9181286549708, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71995670, Length=329, Percent_Identity=26.4437689969605, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320099, Length=362, Percent_Identity=25.9668508287293, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322891, Length=344, Percent_Identity=22.9651162790698, Blast_Score=77, Evalue=4e-15,
Organism=Drosophila melanogaster, GI20129063, Length=367, Percent_Identity=30.5177111716621, Blast_Score=148, Evalue=5e-36,
Organism=Drosophila melanogaster, GI21357207, Length=341, Percent_Identity=25.2199413489736, Blast_Score=108, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 37753; Mature: 37753

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVYGLGIESSCDETSIAIVRDGNEVVSLKVYSQIETHSPYRGVVPEIASRAHLEKINSLL
CEEECCCCCCCCCCEEEEEECCCEEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AVCMEEAKIQFLELKYIAVTGYPGLVGSLMIGAQLARCISLVHSIPIVLVNHLEAHLTVI
HHHHHHHCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEE
GLENELPAFPWLGVLLSGGNSSIYIYKGFGDLQLLADTNDDSLGEAFDKVSAVLGLPYPG
EECCCCCCCCCEEHEEECCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
GPYIEKEALEYKRPKGEKNPFPKLLKEDGPEKIRFSYSGLKTAVLYYLKSLTEPPPIQKI
CCCCCHHHHHHCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHH
SFYFQQTAFELVVRNIKKAIQKTNIKTVVAAGGVLANETLRSVLLAESKTAPFQLYYPQK
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCE
KIYCTDNGAMVACLGYHLWKEKKFVGLDFKVSPKRNFEQII
EEEECCCCCEEEEHHHHHHHCCEEEECEEEECCCCCHHHCC
>Mature Secondary Structure
MVYGLGIESSCDETSIAIVRDGNEVVSLKVYSQIETHSPYRGVVPEIASRAHLEKINSLL
CEEECCCCCCCCCCEEEEEECCCEEEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHH
AVCMEEAKIQFLELKYIAVTGYPGLVGSLMIGAQLARCISLVHSIPIVLVNHLEAHLTVI
HHHHHHHCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEE
GLENELPAFPWLGVLLSGGNSSIYIYKGFGDLQLLADTNDDSLGEAFDKVSAVLGLPYPG
EECCCCCCCCCEEHEEECCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCC
GPYIEKEALEYKRPKGEKNPFPKLLKEDGPEKIRFSYSGLKTAVLYYLKSLTEPPPIQKI
CCCCCHHHHHHCCCCCCCCCCHHHHHCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHH
SFYFQQTAFELVVRNIKKAIQKTNIKTVVAAGGVLANETLRSVLLAESKTAPFQLYYPQK
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHCCCCCCEEEECCCE
KIYCTDNGAMVACLGYHLWKEKKFVGLDFKVSPKRNFEQII
EEEECCCCCEEEEHHHHHHHCCEEEECEEEECCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA