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The map label for this gene is nuoC [H]

Identifier: 183220688

GI number: 183220688

Start: 1352246

End: 1352767

Strand: Direct

Name: nuoC [H]

Synonym: LEPBI_I1298

Alternate gene names: 183220688

Gene position: 1352246-1352767 (Clockwise)

Preceding gene: 183220687

Following gene: 183220689

Centisome position: 37.57

GC content: 43.3

Gene sequence:

>522_bases
ATGAAAGAAAAACTTACCGAATTCATCACAACCCGATTTGTGGATTGTTTACTCCCGCAAAGGGACATAAACACGAATCT
TTTGTACTTCAGCATCCAAAAAGAAAAACTCCCTGAAGTCGTTCGCACTTTAAAAGACCACCCTGAGTTTGCGTTTTCTT
TTTTGAATGACCTCACTTCCATTGACTGGCTCGGAAAACGAGAACCTAGGTTTGAAGTGATTTACCTCCTTCGCTCCCCA
AAACTTGGTCACTTTCGTTTGCAACTCAGAGTGCCCGTAGGGGAAGGGGAATCGGTTCCAAGCCTTTCCGAAATTTTCCC
TGCTGCCAATTGGCCTGAAAGGGAAGTATTTGATCTTATGGGAATTCCATTTTCAGGTCATCCTAGAATGGAAAGACTCA
TCATGCCTGATAATTTTGTAGGCCACCCACTTCGAAAGGATTATCCATTAGAAGGCCCTGGCCAAGACTATCTCATTGAA
GACCTACTGACCATTCACGTAAAAGAGGATATTACCGGTTAG

Upstream 100 bases:

>100_bases
TACAAAAAAAAGTACAAAGCCAAGGATTGGAAGCACGTCGCCAAGAAGTCATGAGAAAGATCGAAGAGATCAATGAACGT
AACAAACCCCTCGTAGTGGC

Downstream 100 bases:

>100_bases
GCGGTAAACAATCATTATGGTAATGTACGAAAAAACAGCCGAACACTTCGGCCAAAAATTCAAAGACCTACCAGAAGGTC
ATTTACTTGTCAACTTAGGG

Product: NADH-quinone oxidoreductase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MKEKLTEFITTRFVDCLLPQRDINTNLLYFSIQKEKLPEVVRTLKDHPEFAFSFLNDLTSIDWLGKREPRFEVIYLLRSP
KLGHFRLQLRVPVGEGESVPSLSEIFPAANWPEREVFDLMGIPFSGHPRMERLIMPDNFVGHPLRKDYPLEGPGQDYLIE
DLLTIHVKEDITG

Sequences:

>Translated_173_residues
MKEKLTEFITTRFVDCLLPQRDINTNLLYFSIQKEKLPEVVRTLKDHPEFAFSFLNDLTSIDWLGKREPRFEVIYLLRSP
KLGHFRLQLRVPVGEGESVPSLSEIFPAANWPEREVFDLMGIPFSGHPRMERLIMPDNFVGHPLRKDYPLEGPGQDYLIE
DLLTIHVKEDITG
>Mature_173_residues
MKEKLTEFITTRFVDCLLPQRDINTNLLYFSIQKEKLPEVVRTLKDHPEFAFSFLNDLTSIDWLGKREPRFEVIYLLRSP
KLGHFRLQLRVPVGEGESVPSLSEIFPAANWPEREVFDLMGIPFSGHPRMERLIMPDNFVGHPLRKDYPLEGPGQDYLIE
DLLTIHVKEDITG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=152, Percent_Identity=33.5526315789474, Blast_Score=88, Evalue=4e-18,
Organism=Escherichia coli, GI145693162, Length=125, Percent_Identity=40.8, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71990788, Length=113, Percent_Identity=38.0530973451327, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI32563621, Length=113, Percent_Identity=38.0530973451327, Blast_Score=78, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24656494, Length=121, Percent_Identity=37.1900826446281, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- InterPro:   IPR020396
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 20151; Mature: 20151

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKLTEFITTRFVDCLLPQRDINTNLLYFSIQKEKLPEVVRTLKDHPEFAFSFLNDLTS
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
IDWLGKREPRFEVIYLLRSPKLGHFRLQLRVPVGEGESVPSLSEIFPAANWPEREVFDLM
HHHCCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHH
GIPFSGHPRMERLIMPDNFVGHPLRKDYPLEGPGQDYLIEDLLTIHVKEDITG
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHECCCCCC
>Mature Secondary Structure
MKEKLTEFITTRFVDCLLPQRDINTNLLYFSIQKEKLPEVVRTLKDHPEFAFSFLNDLTS
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
IDWLGKREPRFEVIYLLRSPKLGHFRLQLRVPVGEGESVPSLSEIFPAANWPEREVFDLM
HHHCCCCCCCEEEEEEECCCCCCEEEEEEEEECCCCCCCCCHHHHCCCCCCCCHHHHHHH
GIPFSGHPRMERLIMPDNFVGHPLRKDYPLEGPGQDYLIEDLLTIHVKEDITG
CCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA