Click here to switch to the map view.

The map label for this gene is mmgC [H]

Identifier: 183220651

GI number: 183220651

Start: 1304279

End: 1306036

Strand: Direct

Name: mmgC [H]

Synonym: LEPBI_I1259

Alternate gene names: 183220651

Gene position: 1304279-1306036 (Clockwise)

Preceding gene: 183220650

Following gene: 183220652

Centisome position: 36.23

GC content: 43.0

Gene sequence:

>1758_bases
ATGATATCTAATAACTATTTTAATGATAATGATGACTTAATTGATCATTTCGATTCTCTCACACCTTGGAATGCGGTGAT
CGACCAATACGAACAAGGGTTCGAAGATTTTGCCGAATTCCAAAAATCAGGGAAAGAGGAATTAACCTTTGCACCTGGAA
ATTACGAAGATGCCATCGAATTTTACCGTTCCACGTTGGAAGCGGGTGGGGACATTGCAGGAAACGACATCTCTCAAATT
GCCAAACAAATGGATGAAGAGGGACTCAAATACAAAGACGGACAAGTTGGATTCCCTAAATCAATGTTAGATGTTACGGA
AAAAATCAAATCAGCAGGTTTATTACCGTATGGAATCCACAGGCATTACGGTGGACTAGGATTACCTTCTGTCGTACAAT
CGATGTTATCTGAATGTGTTTCTCGTGGAGACGGATCTCTTGCGATCACTCTTGGTTGTATGAACCTTGCCGAAACTGTT
GAACGTTTTGGAACAGAGGAAATGATCCATGAATTTGTTCCCAAAATGGCCGCAGGAGAACTTTGTGGGGCAATGGCTCT
CACAGAACCTAATTACGGTTCTGACCTTCCGAACTTACAAACAAAAGCTGTGAAAGGGGAAGATGGAGTGTGGCGGATCA
CTGGGACAAAACGTTTCATCACCCATGCATGTGGATTTGGTGATGCACCATCCATCATCTTAACTTTGGCACGAACTGGT
TCCACAACCAGTGGCGCTCGTGGTCTCTCTTTCTTCTTAGTTCATTCCAAAGATGTGTTTGTCGCATCCATCGAAAAGAA
AATGGGTCTTCATTGTTCTCCTACTTGCGAAGTGGTATTTGAAAATGCACCAGGCATTCTCATCGGTGAAGAGGGCAAAG
GACTCGTGAAGTATTCCATGGCGATGATGAACCAAGCTCGTCTAAACATTGCCGCACAGGCCATGGGAATTGCAACCGCA
GCGTATTTCGAAGGAAAGAAGTATGCAGAAGAACGAGTCCAATTTGGAAAAACCATTAGTAACATCACCGCAGTGAAAAA
AATGTTGGAGCGGATGGAACGAGAAGTGGCGGCTATGCGTTGTATTCTTTATGAAGCAAGTTTTGCTGTGGACCAATACC
GTTGGAAAGAAGAACGAGGCAAGATGAAAGGCCTCACCGAAAAGGACATCAAAAAAGATGAAACTTTTAAAAAATGGGAA
AAACTTGCCTCACTATTCACTCCACTTTCCAAGTATTACATCACGGAAATGGCAAACGTTGTCGCATACGACGCTCTGCA
AATCCATGGTGGGTCGGGTTACACTGAAGATTATGATGTGGCACGTTTGTATCGAGATGTTCGGATCACAAACATCTATG
AAGGTACCACACAACTCCAAACGGTAGCTTGTATCGGTGGTATTGTTTCCGGAATGACAGAAACTGGAATTTATCGTGAA
TACCTAAAATCGGAAATGGCCGGATTTGTTTCATCCTCCGAGCTAAACGATCTATTCAAACAATTCGAAACAGTTGTGGC
GGAATTTGCAGAAATTGATTCGACTCCGCTTCGCGAAGAGTTGGCATTTGAAGTGGTGGAATCGGCAGCTAGATTTCATA
ACAGTATGTTACTCGAAAGAAGTGTGGGAAGGTCCAAAGTCGAAAGAAGGGCACATAGAAAGTCTCTGACTGAAAGTTAT
ATTTTAGACAGTGCGGCTGTTCTTGCAGCCAACCTAACCAAAATACGTGGAAAGAAAAAAACTCCAGTCACTGCATAA

Upstream 100 bases:

>100_bases
ATTTGACGTTTGTTCAGAAATCAACAAGGGAAAATTATTTGTAATTCTTTTCCCTATATTGAATGGTGAGTGAAAGTCCT
GGTCTGGAGCCAATAATTGT

Downstream 100 bases:

>100_bases
CGATCTTCTGGATGAACCTCTTCTTCCCTGTTACGCTTGTTTTGCGGGGAAAGGAGAGGTTGAAATTTCTGCCAATTTAA
TCGATACTCGAATTTCCTCT

Product: acyl-CoA dehydrogenase family protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MISNNYFNDNDDLIDHFDSLTPWNAVIDQYEQGFEDFAEFQKSGKEELTFAPGNYEDAIEFYRSTLEAGGDIAGNDISQI
AKQMDEEGLKYKDGQVGFPKSMLDVTEKIKSAGLLPYGIHRHYGGLGLPSVVQSMLSECVSRGDGSLAITLGCMNLAETV
ERFGTEEMIHEFVPKMAAGELCGAMALTEPNYGSDLPNLQTKAVKGEDGVWRITGTKRFITHACGFGDAPSIILTLARTG
STTSGARGLSFFLVHSKDVFVASIEKKMGLHCSPTCEVVFENAPGILIGEEGKGLVKYSMAMMNQARLNIAAQAMGIATA
AYFEGKKYAEERVQFGKTISNITAVKKMLERMEREVAAMRCILYEASFAVDQYRWKEERGKMKGLTEKDIKKDETFKKWE
KLASLFTPLSKYYITEMANVVAYDALQIHGGSGYTEDYDVARLYRDVRITNIYEGTTQLQTVACIGGIVSGMTETGIYRE
YLKSEMAGFVSSSELNDLFKQFETVVAEFAEIDSTPLREELAFEVVESAARFHNSMLLERSVGRSKVERRAHRKSLTESY
ILDSAAVLAANLTKIRGKKKTPVTA

Sequences:

>Translated_585_residues
MISNNYFNDNDDLIDHFDSLTPWNAVIDQYEQGFEDFAEFQKSGKEELTFAPGNYEDAIEFYRSTLEAGGDIAGNDISQI
AKQMDEEGLKYKDGQVGFPKSMLDVTEKIKSAGLLPYGIHRHYGGLGLPSVVQSMLSECVSRGDGSLAITLGCMNLAETV
ERFGTEEMIHEFVPKMAAGELCGAMALTEPNYGSDLPNLQTKAVKGEDGVWRITGTKRFITHACGFGDAPSIILTLARTG
STTSGARGLSFFLVHSKDVFVASIEKKMGLHCSPTCEVVFENAPGILIGEEGKGLVKYSMAMMNQARLNIAAQAMGIATA
AYFEGKKYAEERVQFGKTISNITAVKKMLERMEREVAAMRCILYEASFAVDQYRWKEERGKMKGLTEKDIKKDETFKKWE
KLASLFTPLSKYYITEMANVVAYDALQIHGGSGYTEDYDVARLYRDVRITNIYEGTTQLQTVACIGGIVSGMTETGIYRE
YLKSEMAGFVSSSELNDLFKQFETVVAEFAEIDSTPLREELAFEVVESAARFHNSMLLERSVGRSKVERRAHRKSLTESY
ILDSAAVLAANLTKIRGKKKTPVTA
>Mature_585_residues
MISNNYFNDNDDLIDHFDSLTPWNAVIDQYEQGFEDFAEFQKSGKEELTFAPGNYEDAIEFYRSTLEAGGDIAGNDISQI
AKQMDEEGLKYKDGQVGFPKSMLDVTEKIKSAGLLPYGIHRHYGGLGLPSVVQSMLSECVSRGDGSLAITLGCMNLAETV
ERFGTEEMIHEFVPKMAAGELCGAMALTEPNYGSDLPNLQTKAVKGEDGVWRITGTKRFITHACGFGDAPSIILTLARTG
STTSGARGLSFFLVHSKDVFVASIEKKMGLHCSPTCEVVFENAPGILIGEEGKGLVKYSMAMMNQARLNIAAQAMGIATA
AYFEGKKYAEERVQFGKTISNITAVKKMLERMEREVAAMRCILYEASFAVDQYRWKEERGKMKGLTEKDIKKDETFKKWE
KLASLFTPLSKYYITEMANVVAYDALQIHGGSGYTEDYDVARLYRDVRITNIYEGTTQLQTVACIGGIVSGMTETGIYRE
YLKSEMAGFVSSSELNDLFKQFETVVAEFAEIDSTPLREELAFEVVESAARFHNSMLLERSVGRSKVERRAHRKSLTESY
ILDSAAVLAANLTKIRGKKKTPVTA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=365, Percent_Identity=31.2328767123288, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI4557233, Length=417, Percent_Identity=28.7769784172662, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI4501859, Length=368, Percent_Identity=28.2608695652174, Blast_Score=134, Evalue=3e-31,
Organism=Homo sapiens, GI21361497, Length=390, Percent_Identity=29.2307692307692, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI7656849, Length=371, Percent_Identity=28.8409703504043, Blast_Score=126, Evalue=7e-29,
Organism=Homo sapiens, GI4557231, Length=359, Percent_Identity=29.2479108635098, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI187960098, Length=359, Percent_Identity=29.2479108635098, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=26.4705882352941, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=26.7029972752044, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4557235, Length=362, Percent_Identity=28.1767955801105, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI76496475, Length=362, Percent_Identity=28.1767955801105, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI4503943, Length=359, Percent_Identity=23.9554317548747, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI7669494, Length=341, Percent_Identity=24.0469208211144, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI87081958, Length=391, Percent_Identity=28.3887468030691, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1786223, Length=307, Percent_Identity=25.4071661237785, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87082384, Length=301, Percent_Identity=26.2458471760797, Blast_Score=98, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=371, Percent_Identity=30.7277628032345, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17508101, Length=361, Percent_Identity=30.7479224376731, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17569725, Length=426, Percent_Identity=27.9342723004695, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=28.4153005464481, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570075, Length=383, Percent_Identity=27.4151436031332, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=26.6304347826087, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17533517, Length=362, Percent_Identity=25.9668508287293, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI71985184, Length=370, Percent_Identity=26.2162162162162, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI86563383, Length=332, Percent_Identity=26.8072289156627, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI86563381, Length=332, Percent_Identity=26.8072289156627, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71990804, Length=263, Percent_Identity=27.7566539923954, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=346, Percent_Identity=27.4566473988439, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17534353, Length=376, Percent_Identity=24.2021276595745, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17505929, Length=352, Percent_Identity=24.4318181818182, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985192, Length=315, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=27.4261603375527, Blast_Score=82, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI71982178, Length=286, Percent_Identity=26.9230769230769, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21356377, Length=407, Percent_Identity=28.2555282555283, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI24646207, Length=364, Percent_Identity=30.2197802197802, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24666513, Length=400, Percent_Identity=30, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24660351, Length=394, Percent_Identity=29.4416243654822, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI281363737, Length=374, Percent_Identity=28.8770053475936, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21355753, Length=372, Percent_Identity=27.6881720430108, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19920834, Length=424, Percent_Identity=24.5283018867925, Blast_Score=86, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 64837; Mature: 64837

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISNNYFNDNDDLIDHFDSLTPWNAVIDQYEQGFEDFAEFQKSGKEELTFAPGNYEDAIE
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHH
FYRSTLEAGGDIAGNDISQIAKQMDEEGLKYKDGQVGFPKSMLDVTEKIKSAGLLPYGIH
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHH
RHYGGLGLPSVVQSMLSECVSRGDGSLAITLGCMNLAETVERFGTEEMIHEFVPKMAAGE
HHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LCGAMALTEPNYGSDLPNLQTKAVKGEDGVWRITGTKRFITHACGFGDAPSIILTLARTG
HHHHHHCCCCCCCCCCCCCCHHEECCCCCEEEEECCHHHHHHHCCCCCCCHHHEEEECCC
STTSGARGLSFFLVHSKDVFVASIEKKMGLHCSPTCEVVFENAPGILIGEEGKGLVKYSM
CCCCCCCCCEEEEEECCCHHEEEHHHHHCCCCCCCHHEEEECCCCEEECCCCCCHHHHHH
AMMNQARLNIAAQAMGIATAAYFEGKKYAEERVQFGKTISNITAVKKMLERMEREVAAMR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CILYEASFAVDQYRWKEERGKMKGLTEKDIKKDETFKKWEKLASLFTPLSKYYITEMANV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAYDALQIHGGSGYTEDYDVARLYRDVRITNIYEGTTQLQTVACIGGIVSGMTETGIYRE
HHHHHEEEECCCCCCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
YLKSEMAGFVSSSELNDLFKQFETVVAEFAEIDSTPLREELAFEVVESAARFHNSMLLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVGRSKVERRAHRKSLTESYILDSAAVLAANLTKIRGKKKTPVTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MISNNYFNDNDDLIDHFDSLTPWNAVIDQYEQGFEDFAEFQKSGKEELTFAPGNYEDAIE
CCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHH
FYRSTLEAGGDIAGNDISQIAKQMDEEGLKYKDGQVGFPKSMLDVTEKIKSAGLLPYGIH
HHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHH
RHYGGLGLPSVVQSMLSECVSRGDGSLAITLGCMNLAETVERFGTEEMIHEFVPKMAAGE
HHCCCCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
LCGAMALTEPNYGSDLPNLQTKAVKGEDGVWRITGTKRFITHACGFGDAPSIILTLARTG
HHHHHHCCCCCCCCCCCCCCHHEECCCCCEEEEECCHHHHHHHCCCCCCCHHHEEEECCC
STTSGARGLSFFLVHSKDVFVASIEKKMGLHCSPTCEVVFENAPGILIGEEGKGLVKYSM
CCCCCCCCCEEEEEECCCHHEEEHHHHHCCCCCCCHHEEEECCCCEEECCCCCCHHHHHH
AMMNQARLNIAAQAMGIATAAYFEGKKYAEERVQFGKTISNITAVKKMLERMEREVAAMR
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
CILYEASFAVDQYRWKEERGKMKGLTEKDIKKDETFKKWEKLASLFTPLSKYYITEMANV
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAYDALQIHGGSGYTEDYDVARLYRDVRITNIYEGTTQLQTVACIGGIVSGMTETGIYRE
HHHHHEEEECCCCCCCCHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHHHH
YLKSEMAGFVSSSELNDLFKQFETVVAEFAEIDSTPLREELAFEVVESAARFHNSMLLER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SVGRSKVERRAHRKSLTESYILDSAAVLAANLTKIRGKKKTPVTA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]