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The map label for this gene is rsmA [H]

Identifier: 183220525

GI number: 183220525

Start: 1173841

End: 1174611

Strand: Reverse

Name: rsmA [H]

Synonym: LEPBI_I1126

Alternate gene names: 183220525

Gene position: 1174611-1173841 (Counterclockwise)

Preceding gene: 183220526

Following gene: 183220524

Centisome position: 32.63

GC content: 41.76

Gene sequence:

>771_bases
GTGGAGTACATTGTCAATGTCGCAAAACCACTGTTTTCTGAGGGAGATGTCACACTCGCAGAAATAGGAATTGGTCTTGG
TACCTTGACGTATCCTATTTTATGTTTAGAGAAAGAAACGGATTTATTTGAAATTGATCATGCTTACATCCAATTGGCAA
AAGATGAGATCTTACCAAAGTTTCCCCATGCCATTCTTCATGCAGGCGACGCATTGGAAAATTTATTCCATATCTATCCG
AAGAAAGTGTTTGTTTTTGGAAATTTGCCTTACCACCTAACTACCGAAATCATAAACACACTCATCATCAATTGCCGTCA
CTTCCAAGGTGGGATCTTTATGGTGCAAAAGGAATTTGCTGAGCGCCTTGTGAAAGAAACCTCTTCCCTTTCTGTTTTTT
TATCTGCTTTCTGTGAGATCAAATTCCTAAAAACAGTCCATAAAAATTGTTTTTTTCCCATTCCTAAAATCCATTCGGCT
TTGCTCCTGCTCACTCCCAAACAAAAGGTCGGAAACAACCAATGGTCCCCCCAATCGAACGAGGGAGTGGAAATTTGGTC
TCGAATGTTACGCACTCTGTTTTGGGGCAAACGCAAACAAATCCAAGTGAGCCTCCGAGAATCGCCTTTTTCAAACGACC
CAATGTTTCGAGACGCCTTGGGAGAAGCCCTCCTCCGTTCCCAAATCCCCCCGACCAAACGACCAGAAGAATTGAACCGT
GAACAATTTCTGAATCTTGGTCAACATTTGCTTGACATTTTGTCAAAATGA

Upstream 100 bases:

>100_bases
CCCTTACTCCACCATCTCACAAATCCAAAGCTTCTTTGAAGAAAAAGGAATCCGAGCCCAAAAAAAATTTGGTCAAAATT
TCCTAATCGACCAAAACATT

Downstream 100 bases:

>100_bases
TGTCAAATCTACCACGCTATGTTCGAAAATTTCAGAGCCCCTCAAATTGTAACCTTTGCCATCCCAGTTTTTTTCCTTCT
CATCGGGATTGAAGTGTACA

Product: putative dimethyladenosine transferase

Products: NA

Alternate protein names: 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase; 16S rRNA dimethyladenosine transferase; 16S rRNA dimethylase; S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEYIVNVAKPLFSEGDVTLAEIGIGLGTLTYPILCLEKETDLFEIDHAYIQLAKDEILPKFPHAILHAGDALENLFHIYP
KKVFVFGNLPYHLTTEIINTLIINCRHFQGGIFMVQKEFAERLVKETSSLSVFLSAFCEIKFLKTVHKNCFFPIPKIHSA
LLLLTPKQKVGNNQWSPQSNEGVEIWSRMLRTLFWGKRKQIQVSLRESPFSNDPMFRDALGEALLRSQIPPTKRPEELNR
EQFLNLGQHLLDILSK

Sequences:

>Translated_256_residues
MEYIVNVAKPLFSEGDVTLAEIGIGLGTLTYPILCLEKETDLFEIDHAYIQLAKDEILPKFPHAILHAGDALENLFHIYP
KKVFVFGNLPYHLTTEIINTLIINCRHFQGGIFMVQKEFAERLVKETSSLSVFLSAFCEIKFLKTVHKNCFFPIPKIHSA
LLLLTPKQKVGNNQWSPQSNEGVEIWSRMLRTLFWGKRKQIQVSLRESPFSNDPMFRDALGEALLRSQIPPTKRPEELNR
EQFLNLGQHLLDILSK
>Mature_256_residues
MEYIVNVAKPLFSEGDVTLAEIGIGLGTLTYPILCLEKETDLFEIDHAYIQLAKDEILPKFPHAILHAGDALENLFHIYP
KKVFVFGNLPYHLTTEIINTLIINCRHFQGGIFMVQKEFAERLVKETSSLSVFLSAFCEIKFLKTVHKNCFFPIPKIHSA
LLLLTPKQKVGNNQWSPQSNEGVEIWSRMLRTLFWGKRKQIQVSLRESPFSNDPMFRDALGEALLRSQIPPTKRPEELNR
EQFLNLGQHLLDILSK

Specific function: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits [H]

COG id: COG0030

COG function: function code J; Dimethyladenosine transferase (rRNA methylation)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786236, Length=250, Percent_Identity=26.8, Blast_Score=68, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25146882, Length=198, Percent_Identity=28.7878787878788, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358017, Length=265, Percent_Identity=26.0377358490566, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023165
- InterPro:   IPR020596
- InterPro:   IPR001737
- InterPro:   IPR020598
- InterPro:   IPR011530 [H]

Pfam domain/function: PF00398 RrnaAD [H]

EC number: =2.1.1.182 [H]

Molecular weight: Translated: 29375; Mature: 29375

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYIVNVAKPLFSEGDVTLAEIGIGLGTLTYPILCLEKETDLFEIDHAYIQLAKDEILPK
CCHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCC
FPHAILHAGDALENLFHIYPKKVFVFGNLPYHLTTEIINTLIINCRHFQGGIFMVQKEFA
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
ERLVKETSSLSVFLSAFCEIKFLKTVHKNCFFPIPKIHSALLLLTPKQKVGNNQWSPQSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCEEEEECCHHHHCCCCCCCCCC
EGVEIWSRMLRTLFWGKRKQIQVSLRESPFSNDPMFRDALGEALLRSQIPPTKRPEELNR
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCH
EQFLNLGQHLLDILSK
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEYIVNVAKPLFSEGDVTLAEIGIGLGTLTYPILCLEKETDLFEIDHAYIQLAKDEILPK
CCHHHHHHHHHHCCCCEEHHHHHCCHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHCCC
FPHAILHAGDALENLFHIYPKKVFVFGNLPYHLTTEIINTLIINCRHFQGGIFMVQKEFA
CCHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHHH
ERLVKETSSLSVFLSAFCEIKFLKTVHKNCFFPIPKIHSALLLLTPKQKVGNNQWSPQSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCEEEEECCHHHHCCCCCCCCCC
EGVEIWSRMLRTLFWGKRKQIQVSLRESPFSNDPMFRDALGEALLRSQIPPTKRPEELNR
CCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCH
EQFLNLGQHLLDILSK
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10993077 [H]