Click here to switch to the map view.

The map label for this gene is prmA [H]

Identifier: 183220519

GI number: 183220519

Start: 1168374

End: 1169300

Strand: Reverse

Name: prmA [H]

Synonym: LEPBI_I1120

Alternate gene names: 183220519

Gene position: 1169300-1168374 (Counterclockwise)

Preceding gene: 183220520

Following gene: 183220517

Centisome position: 32.48

GC content: 36.68

Gene sequence:

>927_bases
TTGGAATATAGAGAATTAAAAGTCAATTTACCAAAAGAATTATCAGATCCGTTTTACGAACTCCTCGATTCTTTACAATG
TGCTGGTTATTACGAAATTCTGTTTGATGGAGAAGCTCCCAAAGAAAAAGACCAGGGACTCATCCGTGACAACACAAACA
TTCGTATTTATTTACAAACGTATGAAGTGGAAAAAGAATTAAAAATTTTAATTTTTTTAAAACTGTTTGCACCTAACAAT
TCTAACTCGGAATCACGCATCATCGAAACAAGAGATTATGAAGAGGCTTACAAAGAATATTATAAACCTTTCCCCATTGG
GAAAAAACTTTGGGTCATCCCTACTTGGGAAAAACAAGAACCAAATACCATTTCTCTTTGGGAGCCGAATGGTGGAATCC
CTCTATTTATCAATCCAGGTGTTGCCTTCGGAACAGGACATCACGAAACAACGAAACTCATCTTAGAACATTTGGATTCA
TTGTATGAGGAAGGTAAGTTCTCATTTACTTCTGCATGTGATGTGGGAACAGGATCGGGAATTTTATCGATTGGACTTGC
GAAGTTTGGTGTTAGCAAAATTTTTGCTTTGGACATAGACCCCAATGCTGTAAAAGCAGCTTGGTCTAATTGGACAGAAA
ACGAATACCCAAAAGGATTCCAATTCAGTGTGGAAGAATCAGGGATCGACAATCCAAAATTATCCAACCAACACTACGAC
CTAGCAATCGCCAATATCACCTTTGCTGTTTTATCACAAAACATTCGTCATCTGGCAAAAATCAATGCTCCAAGAATTAT
TTTTTCAGGAATCATCACAGAAAAAAAAGATGATTTTTTAAGTTTATTACAGAGTCACTTGCCTGGTAAACTCCTCTATT
CCAAAGAATGGAACGAGTGGTGGGTTCTTGATTGGCAAAGAAATTAA

Upstream 100 bases:

>100_bases
TGTTTTTTAAGGCAGATGTCTCACATGAATATTCCAATCCCACGGATCAGGAAACACTGATGTACTTGGTGATGGACTAT
ACAGACGAAATAGGTTAAAT

Downstream 100 bases:

>100_bases
TCTCGGTTTAAAAACTTAATCAAACTGACTTGATTTCCTTTGTCATTGTATTCAATCCGATCAAAAACAGATTTTGTCAT
AAGAATCCCACGTCCATGTT

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MEYRELKVNLPKELSDPFYELLDSLQCAGYYEILFDGEAPKEKDQGLIRDNTNIRIYLQTYEVEKELKILIFLKLFAPNN
SNSESRIIETRDYEEAYKEYYKPFPIGKKLWVIPTWEKQEPNTISLWEPNGGIPLFINPGVAFGTGHHETTKLILEHLDS
LYEEGKFSFTSACDVGTGSGILSIGLAKFGVSKIFALDIDPNAVKAAWSNWTENEYPKGFQFSVEESGIDNPKLSNQHYD
LAIANITFAVLSQNIRHLAKINAPRIIFSGIITEKKDDFLSLLQSHLPGKLLYSKEWNEWWVLDWQRN

Sequences:

>Translated_308_residues
MEYRELKVNLPKELSDPFYELLDSLQCAGYYEILFDGEAPKEKDQGLIRDNTNIRIYLQTYEVEKELKILIFLKLFAPNN
SNSESRIIETRDYEEAYKEYYKPFPIGKKLWVIPTWEKQEPNTISLWEPNGGIPLFINPGVAFGTGHHETTKLILEHLDS
LYEEGKFSFTSACDVGTGSGILSIGLAKFGVSKIFALDIDPNAVKAAWSNWTENEYPKGFQFSVEESGIDNPKLSNQHYD
LAIANITFAVLSQNIRHLAKINAPRIIFSGIITEKKDDFLSLLQSHLPGKLLYSKEWNEWWVLDWQRN
>Mature_308_residues
MEYRELKVNLPKELSDPFYELLDSLQCAGYYEILFDGEAPKEKDQGLIRDNTNIRIYLQTYEVEKELKILIFLKLFAPNN
SNSESRIIETRDYEEAYKEYYKPFPIGKKLWVIPTWEKQEPNTISLWEPNGGIPLFINPGVAFGTGHHETTKLILEHLDS
LYEEGKFSFTSACDVGTGSGILSIGLAKFGVSKIFALDIDPNAVKAAWSNWTENEYPKGFQFSVEESGIDNPKLSNQHYD
LAIANITFAVLSQNIRHLAKINAPRIIFSGIITEKKDDFLSLLQSHLPGKLLYSKEWNEWWVLDWQRN

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=174, Percent_Identity=32.7586206896552, Blast_Score=85, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 35423; Mature: 35423

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYRELKVNLPKELSDPFYELLDSLQCAGYYEILFDGEAPKEKDQGLIRDNTNIRIYLQT
CCCCEEEECCCHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCEEEEEEE
YEVEKELKILIFLKLFAPNNSNSESRIIETRDYEEAYKEYYKPFPIGKKLWVIPTWEKQE
EECCCCEEEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCCC
PNTISLWEPNGGIPLFINPGVAFGTGHHETTKLILEHLDSLYEEGKFSFTSACDVGTGSG
CCEEEEECCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
ILSIGLAKFGVSKIFALDIDPNAVKAAWSNWTENEYPKGFQFSVEESGIDNPKLSNQHYD
HHHHHHHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEE
LAIANITFAVLSQNIRHLAKINAPRIIFSGIITEKKDDFLSLLQSHLPGKLLYSKEWNEW
EEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHCCCEEEEECCCCEE
WVLDWQRN
EEEEEECC
>Mature Secondary Structure
MEYRELKVNLPKELSDPFYELLDSLQCAGYYEILFDGEAPKEKDQGLIRDNTNIRIYLQT
CCCCEEEECCCHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEECCCCEEEEEEE
YEVEKELKILIFLKLFAPNNSNSESRIIETRDYEEAYKEYYKPFPIGKKLWVIPTWEKQE
EECCCCEEEEEEEEEECCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCEEEEEECCCCCC
PNTISLWEPNGGIPLFINPGVAFGTGHHETTKLILEHLDSLYEEGKFSFTSACDVGTGSG
CCEEEEECCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
ILSIGLAKFGVSKIFALDIDPNAVKAAWSNWTENEYPKGFQFSVEESGIDNPKLSNQHYD
HHHHHHHHHCCEEEEEEECCCCHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEE
LAIANITFAVLSQNIRHLAKINAPRIIFSGIITEKKDDFLSLLQSHLPGKLLYSKEWNEW
EEEHHHHHHHHHHHHHHHHHCCCCEEEEEHHHCCCCHHHHHHHHHHCCCEEEEECCCCEE
WVLDWQRN
EEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA