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The map label for this gene is glpD [H]

Identifier: 183220159

GI number: 183220159

Start: 763850

End: 765457

Strand: Direct

Name: glpD [H]

Synonym: LEPBI_I0747

Alternate gene names: 183220159

Gene position: 763850-765457 (Clockwise)

Preceding gene: 183220158

Following gene: 183220160

Centisome position: 21.22

GC content: 39.49

Gene sequence:

>1608_bases
TTGAGTTTAAAATTGGATCGTTTCATTGAATCCTATCAGGGAGAATCTTTCGATGTGACCATCATTGGCGGTGGGATCAC
TGGTGCTACACTCGCGTATGAAGTGGCAAGTCGCGGAGGATCCGTTTGTCTTGTTGAAAAAAAAGACTTTGGCGGAGCCA
CATCAGCTGCCACTGGAAAACTCATCCATGGTGGCCTTCGGTATCTAAAACAATTTGAAATTGGCCTTGTCAGAGAAGCA
TTAAAAGAAAGAAGGAATTTGTCAAACATTGCACCTAACTTAGTTTATCCGTATCCTATGATTTTGCCAAAACCTGGGAT
CATAGCGAGGATGGGACTTCTAGTGTATGATCTTTTGTCTTTTGATAAAGGTTGGACTTGGGACAAATCTAAAAAGATTC
CGAACCACAAGTATCTCAAGCGAGAAGGGCTCAAGAAATTGAATTTAGGAGATTATGAAGATGCTGCTTACTTTTATGAT
GCCATTTGTTTGAGCCCCGAACGATTGACTCTTAGTTTTTTGAAGTCCGCCGTATTGTATGGTGCCAAGATTTCCAATTA
TACGGAAGTGAGAGACCTCTTATGGGATGGAGATAGAGTGGTGGGGGTTCATGTAATGGATTCCATTTCTAATCGAGAAT
ATAAAATCCATTCGAAAGTCACGATCAACGCATCGGGACCTTGGACACAAGATATATTGGCAAAGTCAAAAAAAACAGAA
ACAGTTTTCCCCAAAAAAAGATCGGAAGGGATTTATCTCATCACAAAACAACTCTCTCCCATTATGACTCTGTTTGTCGG
TGAAAAAGGTCATTTTAGTTTTGCACCTTGGCGGGGTCATTCCATGATTGGCCCAACAGAAAAGTCTTACTTTGGTAAGG
TGGAAGATTGGAAGCTGACACGAGAAAGTATCCTTGAGTTTATTGATTACATCAATGAAACTTCACACCTTAATGAAAAA
CTCAAAATGGAGGATGTGATCGCTTCGTATGGAGGTTTACGGCCACTTGCTGAAACAGGCGATGATACGTATTCTGCTTC
TCGCAAATCTGAATTGTATGACCATGAAAAAGATGGAATCAAAGGACTCATCACTGCAGCTGGCGGGAAGTTTACCACAA
GCCGGCATTTTGCAGAATCCATATTTCGTTCCATTCGTAAAAAACTAAATCAAAAAATGAACCCAAGTATTTCCGCAAAA
CAGCACTTATATGGAAGTGGAATTTTAGACATTGAAAGTTTTATCTCTGAATCAAAAGATAAACACAAAGAGTTCTCAGA
AAAAACGATCGATTATCTCATCCGTCATTATGGGTTAGAGTATGAAACGATACTTTCTTTGGTAAAAGAAAATCCGTATT
TGGGAAAGGTTCTTAACGAAGATGGTGAGATCCTAGCGGAAGTGGTTTATGCCATACGGTTCGAAATGGCAAAATCATTG
TCTGATATTTTTTTAAGAAGGACCGGTCTTGGAACGCTTGGTATCCTACCAAAAGAAAAAATGGATCAAATCATCCAAAC
CGCAGCAAAGGAATGGAACTGGTCTCAAACAGAATTGGAAAAAGAATCGAAAAAGATCCAAGATGTTTTGGAATTACCTA
AACTTTAG

Upstream 100 bases:

>100_bases
CTTCACTTCTATTACGACTCGGACTCTGGGACATTCCAAGTGAAAGAGAGAATTTAATCCAACAAATCAAAGTTTGGTTG
CAGATTGGAGGGAAGTCCTT

Downstream 100 bases:

>100_bases
ATGAGTGATCGAAGAAATTCCATTTTGAAATTGTTGATTCGAAATATTGGATGAAAAGAATTTAGGCTGACAAAGAGATT
TCCTGAATTTACCTTATGGT

Product: putative glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MSLKLDRFIESYQGESFDVTIIGGGITGATLAYEVASRGGSVCLVEKKDFGGATSAATGKLIHGGLRYLKQFEIGLVREA
LKERRNLSNIAPNLVYPYPMILPKPGIIARMGLLVYDLLSFDKGWTWDKSKKIPNHKYLKREGLKKLNLGDYEDAAYFYD
AICLSPERLTLSFLKSAVLYGAKISNYTEVRDLLWDGDRVVGVHVMDSISNREYKIHSKVTINASGPWTQDILAKSKKTE
TVFPKKRSEGIYLITKQLSPIMTLFVGEKGHFSFAPWRGHSMIGPTEKSYFGKVEDWKLTRESILEFIDYINETSHLNEK
LKMEDVIASYGGLRPLAETGDDTYSASRKSELYDHEKDGIKGLITAAGGKFTTSRHFAESIFRSIRKKLNQKMNPSISAK
QHLYGSGILDIESFISESKDKHKEFSEKTIDYLIRHYGLEYETILSLVKENPYLGKVLNEDGEILAEVVYAIRFEMAKSL
SDIFLRRTGLGTLGILPKEKMDQIIQTAAKEWNWSQTELEKESKKIQDVLELPKL

Sequences:

>Translated_535_residues
MSLKLDRFIESYQGESFDVTIIGGGITGATLAYEVASRGGSVCLVEKKDFGGATSAATGKLIHGGLRYLKQFEIGLVREA
LKERRNLSNIAPNLVYPYPMILPKPGIIARMGLLVYDLLSFDKGWTWDKSKKIPNHKYLKREGLKKLNLGDYEDAAYFYD
AICLSPERLTLSFLKSAVLYGAKISNYTEVRDLLWDGDRVVGVHVMDSISNREYKIHSKVTINASGPWTQDILAKSKKTE
TVFPKKRSEGIYLITKQLSPIMTLFVGEKGHFSFAPWRGHSMIGPTEKSYFGKVEDWKLTRESILEFIDYINETSHLNEK
LKMEDVIASYGGLRPLAETGDDTYSASRKSELYDHEKDGIKGLITAAGGKFTTSRHFAESIFRSIRKKLNQKMNPSISAK
QHLYGSGILDIESFISESKDKHKEFSEKTIDYLIRHYGLEYETILSLVKENPYLGKVLNEDGEILAEVVYAIRFEMAKSL
SDIFLRRTGLGTLGILPKEKMDQIIQTAAKEWNWSQTELEKESKKIQDVLELPKL
>Mature_534_residues
SLKLDRFIESYQGESFDVTIIGGGITGATLAYEVASRGGSVCLVEKKDFGGATSAATGKLIHGGLRYLKQFEIGLVREAL
KERRNLSNIAPNLVYPYPMILPKPGIIARMGLLVYDLLSFDKGWTWDKSKKIPNHKYLKREGLKKLNLGDYEDAAYFYDA
ICLSPERLTLSFLKSAVLYGAKISNYTEVRDLLWDGDRVVGVHVMDSISNREYKIHSKVTINASGPWTQDILAKSKKTET
VFPKKRSEGIYLITKQLSPIMTLFVGEKGHFSFAPWRGHSMIGPTEKSYFGKVEDWKLTRESILEFIDYINETSHLNEKL
KMEDVIASYGGLRPLAETGDDTYSASRKSELYDHEKDGIKGLITAAGGKFTTSRHFAESIFRSIRKKLNQKMNPSISAKQ
HLYGSGILDIESFISESKDKHKEFSEKTIDYLIRHYGLEYETILSLVKENPYLGKVLNEDGEILAEVVYAIRFEMAKSLS
DIFLRRTGLGTLGILPKEKMDQIIQTAAKEWNWSQTELEKESKKIQDVLELPKL

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=566, Percent_Identity=29.1519434628975, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI285002231, Length=566, Percent_Identity=29.1519434628975, Blast_Score=179, Evalue=7e-45,
Organism=Escherichia coli, GI2367226, Length=465, Percent_Identity=26.6666666666667, Blast_Score=136, Evalue=4e-33,
Organism=Escherichia coli, GI1788574, Length=388, Percent_Identity=26.5463917525773, Blast_Score=93, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI115534726, Length=548, Percent_Identity=30.8394160583942, Blast_Score=162, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17509253, Length=559, Percent_Identity=29.3381037567084, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=606, Percent_Identity=28.3828382838284, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24586295, Length=577, Percent_Identity=26.3431542461005, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI161077125, Length=581, Percent_Identity=27.8829604130809, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24653942, Length=581, Percent_Identity=27.8829604130809, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24653944, Length=581, Percent_Identity=27.8829604130809, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI20130025, Length=581, Percent_Identity=27.8829604130809, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19921278, Length=580, Percent_Identity=24.6551724137931, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 60541; Mature: 60410

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKLDRFIESYQGESFDVTIIGGGITGATLAYEVASRGGSVCLVEKKDFGGATSAATGK
CCCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
LIHGGLRYLKQFEIGLVREALKERRNLSNIAPNLVYPYPMILPKPGIIARMGLLVYDLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FDKGWTWDKSKKIPNHKYLKREGLKKLNLGDYEDAAYFYDAICLSPERLTLSFLKSAVLY
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
GAKISNYTEVRDLLWDGDRVVGVHVMDSISNREYKIHSKVTINASGPWTQDILAKSKKTE
CCCCCCHHHHHHHHHCCCEEEEEEEHHCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCC
TVFPKKRSEGIYLITKQLSPIMTLFVGEKGHFSFAPWRGHSMIGPTEKSYFGKVEDWKLT
CCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHH
RESILEFIDYINETSHLNEKLKMEDVIASYGGLRPLAETGDDTYSASRKSELYDHEKDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCCCC
KGLITAAGGKFTTSRHFAESIFRSIRKKLNQKMNPSISAKQHLYGSGILDIESFISESKD
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHH
KHKEFSEKTIDYLIRHYGLEYETILSLVKENPYLGKVLNEDGEILAEVVYAIRFEMAKSL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
SDIFLRRTGLGTLGILPKEKMDQIIQTAAKEWNWSQTELEKESKKIQDVLELPKL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLKLDRFIESYQGESFDVTIIGGGITGATLAYEVASRGGSVCLVEKKDFGGATSAATGK
CCCHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHH
LIHGGLRYLKQFEIGLVREALKERRNLSNIAPNLVYPYPMILPKPGIIARMGLLVYDLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FDKGWTWDKSKKIPNHKYLKREGLKKLNLGDYEDAAYFYDAICLSPERLTLSFLKSAVLY
CCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHH
GAKISNYTEVRDLLWDGDRVVGVHVMDSISNREYKIHSKVTINASGPWTQDILAKSKKTE
CCCCCCHHHHHHHHHCCCEEEEEEEHHCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCC
TVFPKKRSEGIYLITKQLSPIMTLFVGEKGHFSFAPWRGHSMIGPTEKSYFGKVEDWKLT
CCCCCCCCCCEEEEECHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHH
RESILEFIDYINETSHLNEKLKMEDVIASYGGLRPLAETGDDTYSASRKSELYDHEKDGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHHCCCCCCC
KGLITAAGGKFTTSRHFAESIFRSIRKKLNQKMNPSISAKQHLYGSGILDIESFISESKD
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHHHH
KHKEFSEKTIDYLIRHYGLEYETILSLVKENPYLGKVLNEDGEILAEVVYAIRFEMAKSL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHH
SDIFLRRTGLGTLGILPKEKMDQIIQTAAKEWNWSQTELEKESKKIQDVLELPKL
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]