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The map label for this gene is hfq

Identifier: 183219897

GI number: 183219897

Start: 474353

End: 474604

Strand: Direct

Name: hfq

Synonym: LEPBI_I0479

Alternate gene names: 183219897

Gene position: 474353-474604 (Clockwise)

Preceding gene: 183219896

Following gene: 183219898

Centisome position: 13.18

GC content: 36.51

Gene sequence:

>252_bases
ATGTCGGCAAAAAATAACATCCAAGACCAACTTTTAAATACAGCAAGAAAAGAGAAAATTGATCTCACCATCTACCTGTT
AAATGGAGTGCCCTTAAAAGGAAAGGTTGTCAGTTTTGACAATTTCACCATCATTTTAGAAAACGAAAACAAACAGAATT
TGGTCTATAAACATGCCATTTCGACTATCATCCCAGCAAAACCAATCAAACTTCATAGCGAGGAAACTCCAAAGGAAGCG
GGTGGAGTATAA

Upstream 100 bases:

>100_bases
GTTCAAAAAAGAATCATTCCTTTCGCCCATTTCTTATGATGCCGCTGTCCAATTGTATACAAATATAGAACAAAGATAGA
GAGAACACTCGGGATTTCCA

Downstream 100 bases:

>100_bases
TTCTTTTCTAGTTTTCCTCTTTTTCCCTTTCTAAATTCTGGTTCCAAACCCTATGGCGAAATTACCAAAAGAAACCCCTG
TGGTTCTGATTATGGCGGGA

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 82

Protein sequence:

>83_residues
MSAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAISTIIPAKPIKLHSEETPKEA
GGV

Sequences:

>Translated_83_residues
MSAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAISTIIPAKPIKLHSEETPKEA
GGV
>Mature_82_residues
SAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAISTIIPAKPIKLHSEETPKEAG
GV

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family

Homologues:

Organism=Escherichia coli, GI1790614, Length=82, Percent_Identity=45.1219512195122, Blast_Score=82, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFQ_LEPBA (B0SBH9)

Other databases:

- EMBL:   CP000777
- RefSeq:   YP_001961578.1
- ProteinModelPortal:   B0SBH9
- SMR:   B0SBH9
- GeneID:   6389894
- GenomeReviews:   CP000777_GR
- KEGG:   lbf:LBF_0461
- HOGENOM:   HBG645207
- OMA:   PYLNVLR
- ProtClustDB:   CLSK573953
- BioCyc:   LBIF355278:LBF_0461-MONOMER
- HAMAP:   MF_00436
- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163
- TIGRFAMs:   TIGR02383

Pfam domain/function: PF01423 LSM; SSF50182 Sm_like_riboprot

EC number: NA

Molecular weight: Translated: 9258; Mature: 9127

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAI
CCCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCEEEEEECCCCCCCHHHHHH
STIIPAKPIKLHSEETPKEAGGV
HHHCCCCCEEECCCCCCCCCCCC
>Mature Secondary Structure 
SAKNNIQDQLLNTARKEKIDLTIYLLNGVPLKGKVVSFDNFTIILENENKQNLVYKHAI
CCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCEEEECCCEEEEEECCCCCCCHHHHHH
STIIPAKPIKLHSEETPKEAGGV
HHHCCCCCEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA