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The map label for this gene is pfaP [H]

Identifier: 183219875

GI number: 183219875

Start: 451926

End: 452891

Strand: Direct

Name: pfaP [H]

Synonym: LEPBI_I0456

Alternate gene names: 183219875

Gene position: 451926-452891 (Clockwise)

Preceding gene: 183219872

Following gene: 183219876

Centisome position: 12.55

GC content: 43.06

Gene sequence:

>966_bases
ATGGAAAGAAACCAATTTCTTCTCTTTCTCTCCTTTTTGTTCTCCACAATTGCCACAATTCTTGGAATTGCCATTTTGGT
CTCTGGCTCAAGCCTTGCCCGTTTCTCCAGTGGGACCGGTGGTAGTCTTTTCCAGGCCAGTGAAATTGGAGCCGTCGTTT
TACCCATTGTTGGGGAAATCCATTCGGGGGAATCTACCTTTGATTCCACAGGTGCCGACACCGTATTACGCCAATTACGT
GAATTGGATGAAGATACCAATGTTAAAGGTATTCTCATCGAGATCAATTCCCCAGGCGGAACGGTAGCCGCTTCCCAAGA
AATCTTTAATGAACTCTTACATCTGCGAAAATCCAAAAAGATCGTCGTGAGTATGAAAGATGTGGCCGCTTCCGGTGGAT
ACTATATCGCCGCTGCATCCGATTATATCTTTGCGGAAAACGGAACCATCACTGGATCCATTGGAGTCATTTCATTTGCA
CCGAATGTGAAAGGGTTACTGGACCGTTACGGGGTGGGAGTTCGCACTTACAAAGCGGGCAAATACAAAGACATGTATTC
TCCTTTCCGTGATTCCACAAACGAAGAAGACGATATGATTGGCAAACAACTCCAAGACACCTATCGTAAGTTTGTCGAAG
ATGTTGCCAAAGGAAGGAACAAAACTGTAAAATCCATTGAAGAGTTAGCAGAAGGAAAAATATATTCTGGTGAAGATGCC
TTTCGCAATAAACTCGTGGATGATATTGGCGGAAGAAGGGAAGCTCATAAAAAACTTTCTGAACTTTGCCAATACGAAGG
CCTCATTCCTTTATTTGAACAAGAATATTCTCCTTTTGAAAGGATGATTCGATCTCTTGGTGTGAAGTTTTTAGGGGAAG
GTTCCCAAACTTCCAAAATCCGAGCTCTCTTACAATCGCAAGTTCTTGTGATTTTACCTACGGCACTTGGGAAATTGATG
TTATGA

Upstream 100 bases:

>100_bases
TTCGGCTAACCCGTACAATGAAAATAAACTTTTTCTAAAAAAAAGTAAAGAATTATTAAAGTTGACTCGGGTTTTTGCAA
GGTTTTGCTTGTGGGAGTTT

Downstream 100 bases:

>100_bases
GAGATTTTTTCTTTGATTTGGTTGATACTTTGGAATTGGTATTTCTCGACCCACTTCGTTATTCAGAAGAAGTCAAAGAG
ATTCCCTTTGCCATGAGTCC

Product: peptidase PfaP

Products: NA

Alternate protein names: PF-associated peptidase; Periplasmic flagella-associated protein [H]

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MERNQFLLFLSFLFSTIATILGIAILVSGSSLARFSSGTGGSLFQASEIGAVVLPIVGEIHSGESTFDSTGADTVLRQLR
ELDEDTNVKGILIEINSPGGTVAASQEIFNELLHLRKSKKIVVSMKDVAASGGYYIAAASDYIFAENGTITGSIGVISFA
PNVKGLLDRYGVGVRTYKAGKYKDMYSPFRDSTNEEDDMIGKQLQDTYRKFVEDVAKGRNKTVKSIEELAEGKIYSGEDA
FRNKLVDDIGGRREAHKKLSELCQYEGLIPLFEQEYSPFERMIRSLGVKFLGEGSQTSKIRALLQSQVLVILPTALGKLM
L

Sequences:

>Translated_321_residues
MERNQFLLFLSFLFSTIATILGIAILVSGSSLARFSSGTGGSLFQASEIGAVVLPIVGEIHSGESTFDSTGADTVLRQLR
ELDEDTNVKGILIEINSPGGTVAASQEIFNELLHLRKSKKIVVSMKDVAASGGYYIAAASDYIFAENGTITGSIGVISFA
PNVKGLLDRYGVGVRTYKAGKYKDMYSPFRDSTNEEDDMIGKQLQDTYRKFVEDVAKGRNKTVKSIEELAEGKIYSGEDA
FRNKLVDDIGGRREAHKKLSELCQYEGLIPLFEQEYSPFERMIRSLGVKFLGEGSQTSKIRALLQSQVLVILPTALGKLM
L
>Mature_321_residues
MERNQFLLFLSFLFSTIATILGIAILVSGSSLARFSSGTGGSLFQASEIGAVVLPIVGEIHSGESTFDSTGADTVLRQLR
ELDEDTNVKGILIEINSPGGTVAASQEIFNELLHLRKSKKIVVSMKDVAASGGYYIAAASDYIFAENGTITGSIGVISFA
PNVKGLLDRYGVGVRTYKAGKYKDMYSPFRDSTNEEDDMIGKQLQDTYRKFVEDVAKGRNKTVKSIEELAEGKIYSGEDA
FRNKLVDDIGGRREAHKKLSELCQYEGLIPLFEQEYSPFERMIRSLGVKFLGEGSQTSKIRALLQSQVLVILPTALGKLM
L

Specific function: Possible protease. May be involved in export of periplasmic flagella proteins [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1788064, Length=264, Percent_Identity=32.5757575757576, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1787527, Length=161, Percent_Identity=31.055900621118, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142 [H]

Pfam domain/function: PF01343 Peptidase_S49 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 35095; Mature: 35095

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNQFLLFLSFLFSTIATILGIAILVSGSSLARFSSGTGGSLFQASEIGAVVLPIVGEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEHHCCCEEEEHHHHCC
HSGESTFDSTGADTVLRQLRELDEDTNVKGILIEINSPGGTVAASQEIFNELLHLRKSKK
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCE
IVVSMKDVAASGGYYIAAASDYIFAENGTITGSIGVISFAPNVKGLLDRYGVGVRTYKAG
EEEEEHHHHCCCCEEEEEECCEEEECCCEEEECCEEEEECCCHHHHHHHHCCCEEEECCC
KYKDMYSPFRDSTNEEDDMIGKQLQDTYRKFVEDVAKGRNKTVKSIEELAEGKIYSGEDA
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCHH
FRNKLVDDIGGRREAHKKLSELCQYEGLIPLFEQEYSPFERMIRSLGVKFLGEGSQTSKI
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCCCCEECCCCHHHHH
RALLQSQVLVILPTALGKLML
HHHHHCCHHEEEHHHHHHHCC
>Mature Secondary Structure
MERNQFLLFLSFLFSTIATILGIAILVSGSSLARFSSGTGGSLFQASEIGAVVLPIVGEI
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCEEHHCCCEEEEHHHHCC
HSGESTFDSTGADTVLRQLRELDEDTNVKGILIEINSPGGTVAASQEIFNELLHLRKSKK
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCE
IVVSMKDVAASGGYYIAAASDYIFAENGTITGSIGVISFAPNVKGLLDRYGVGVRTYKAG
EEEEEHHHHCCCCEEEEEECCEEEECCCEEEECCEEEEECCCHHHHHHHHCCCEEEECCC
KYKDMYSPFRDSTNEEDDMIGKQLQDTYRKFVEDVAKGRNKTVKSIEELAEGKIYSGEDA
CCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEECCCHH
FRNKLVDDIGGRREAHKKLSELCQYEGLIPLFEQEYSPFERMIRSLGVKFLGEGSQTSKI
HHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHCCCCEECCCCHHHHH
RALLQSQVLVILPTALGKLML
HHHHHCCHHEEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7628708 [H]