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The map label for this gene is ykhA [H]

Identifier: 183219724

GI number: 183219724

Start: 295693

End: 296202

Strand: Direct

Name: ykhA [H]

Synonym: LEPBI_I0300

Alternate gene names: 183219724

Gene position: 295693-296202 (Clockwise)

Preceding gene: 183219721

Following gene: 183219734

Centisome position: 8.21

GC content: 44.12

Gene sequence:

>510_bases
GTGTCCTCTCCTAATGAATTATCACCCAAGTCACCGCAAGAATCAGCTGTAGAAACTAGACATATCGTTTTGCCTAACGA
TGCCAATCACTACGGAACCGCTTTTGGTGGTGCGATCATGAGTTGGATCGACTTAATAGCTGCCATGTCCGCTCAAAGGC
ATTCGGGAAGGGAAGCAGTTACGGTGAGTATCGATCGAATCAATTTTATCACTCCGATCCAGATTGGTGACCATGTGAAT
CTAAAGGCAATGGTCAATTATGTGGGAACAACTTCGATGGAGGTTGGCGTACAGGTGAACCGCGAAAATCCATATACGGG
TGAGATGGTGAGGGCAACGACCGCTTATCTTTCGTTTGTTGCATTAGATGAAAATAAAAAACCAGCTCCAGTTCCACCTT
TGAAGTTAGAGACGGATCTCGAAAAACGAAGGTTTGCCGAGGGAAAAATGCGAATCGAAATGGCAAAAGAATTTTCTGCA
AAAATCAAAGCCAATCGGAAGATCCTTTAA

Upstream 100 bases:

>100_bases
GTCAGTGATCATTTGCCCTTTACTTCCAAAATTTGTCTAATGTCGGCATGTTTAAAAAAGTCTTTTCGAAACAAAACGTC
AAGACTAAGTTATCCTCATT

Downstream 100 bases:

>100_bases
TCCACGAAACGTTCGTACTCTGCAATTTGTGTTGTACTTTCAACGGAAGGTACAAAGTATTTTTCTCGAACTTTTTTGTA
TTCGGGATCTGCAAAAAAGT

Product: acetyl-CoA hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 169; Mature: 168

Protein sequence:

>169_residues
MSSPNELSPKSPQESAVETRHIVLPNDANHYGTAFGGAIMSWIDLIAAMSAQRHSGREAVTVSIDRINFITPIQIGDHVN
LKAMVNYVGTTSMEVGVQVNRENPYTGEMVRATTAYLSFVALDENKKPAPVPPLKLETDLEKRRFAEGKMRIEMAKEFSA
KIKANRKIL

Sequences:

>Translated_169_residues
MSSPNELSPKSPQESAVETRHIVLPNDANHYGTAFGGAIMSWIDLIAAMSAQRHSGREAVTVSIDRINFITPIQIGDHVN
LKAMVNYVGTTSMEVGVQVNRENPYTGEMVRATTAYLSFVALDENKKPAPVPPLKLETDLEKRRFAEGKMRIEMAKEFSA
KIKANRKIL
>Mature_168_residues
SSPNELSPKSPQESAVETRHIVLPNDANHYGTAFGGAIMSWIDLIAAMSAQRHSGREAVTVSIDRINFITPIQIGDHVNL
KAMVNYVGTTSMEVGVQVNRENPYTGEMVRATTAYLSFVALDENKKPAPVPPLKLETDLEKRRFAEGKMRIEMAKEFSAK
IKANRKIL

Specific function: Unknown

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI22165400, Length=159, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI22165355, Length=159, Percent_Identity=33.3333333333333, Blast_Score=86, Evalue=1e-17,
Organism=Homo sapiens, GI32528284, Length=134, Percent_Identity=35.0746268656716, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI32528286, Length=133, Percent_Identity=34.5864661654135, Blast_Score=84, Evalue=4e-17,
Organism=Homo sapiens, GI32528282, Length=134, Percent_Identity=35.0746268656716, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI75709208, Length=133, Percent_Identity=34.5864661654135, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI18640736, Length=153, Percent_Identity=29.4117647058824, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1787506, Length=124, Percent_Identity=32.258064516129, Blast_Score=65, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 18713; Mature: 18582

Theoretical pI: Translated: 9.42; Mature: 9.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPNELSPKSPQESAVETRHIVLPNDANHYGTAFGGAIMSWIDLIAAMSAQRHSGREAV
CCCCCCCCCCCCCCHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVSIDRINFITPIQIGDHVNLKAMVNYVGTTSMEVGVQVNRENPYTGEMVRATTAYLSFV
EEEECCEEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHEEEE
ALDENKKPAPVPPLKLETDLEKRRFAEGKMRIEMAKEFSAKIKANRKIL
EECCCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SSPNELSPKSPQESAVETRHIVLPNDANHYGTAFGGAIMSWIDLIAAMSAQRHSGREAV
CCCCCCCCCCCCCHHHCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEE
TVSIDRINFITPIQIGDHVNLKAMVNYVGTTSMEVGVQVNRENPYTGEMVRATTAYLSFV
EEEECCEEEEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHHHHEEEE
ALDENKKPAPVPPLKLETDLEKRRFAEGKMRIEMAKEFSAKIKANRKIL
EECCCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8682784; 9384377; 10568751 [H]