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The map label for this gene is lepB1 [H]

Identifier: 183219683

GI number: 183219683

Start: 251371

End: 251970

Strand: Reverse

Name: lepB1 [H]

Synonym: LEPBI_I0258

Alternate gene names: 183219683

Gene position: 251970-251371 (Counterclockwise)

Preceding gene: 183219687

Following gene: 183219682

Centisome position: 7.0

GC content: 39.83

Gene sequence:

>600_bases
ATGGAAACAGAAACTAAAGGCCCCCAATGGTGGTTCAAAATCAAACGATACATGAGAAGAAGCCTTTATGTCTTCCTCTT
TCTCTGTTTTTTACTTTTTGTCCGGGTCTTTTTATTCCAAATCTATTCCGTCCAAGGCAATTCGATGTACCCGACCTTAG
AACACGGGTCTGTGGTCTTTGTTTGGAAAGCAGGATTTGCCATCTCAGCCAAATTTTTTGGAACGGAACTATTATACACA
GAGCCAAACATCAATAAATTGGATTTAGTGCTTTTTGTGAGCCAGGAAGATGAACTAGTCGTCAAACGAGTGATAGGTTT
GCCTGGTGAATTTTATTCGATTGAGGCAGGTCGAGTTCTCATCGACGCAAAAGAATTATTAGAAAATTATTTACCAAAAG
GCACTTATACCAGTGAGCCTTCCACTTCCGTATTTTTAAATCGCCATCATTCCCCGTTTCTTGCCATGGACAAACAAGGG
AGGATTCCTCCAGGATATTTTCTCTTGCTTGGTGACAATCGTCAGTATTCTACTGACTCTAGATCCTTTGGTCTAGTGCC
CGTGGAAAAAATCAAAGGAAAGGTAATCTTTTATTTTTAA

Upstream 100 bases:

>100_bases
GACATAGACTTCTCTAGGCTTCAGATTTACGGAAACTTCCTTTTCCATTCTTTGGAAAGGGGAAAAATGCACGAATGATT
TTTATCGTTTTTTGATGGAT

Downstream 100 bases:

>100_bases
CAATGACAGAATACAAACTTCGTTTTCAGTACATCTTCTATTTTATCTTATCCTTATTTGCCGTTTTGTTTTTCCGAGTG
GTGTATCTCACCTACTTTAA

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
METETKGPQWWFKIKRYMRRSLYVFLFLCFLLFVRVFLFQIYSVQGNSMYPTLEHGSVVFVWKAGFAISAKFFGTELLYT
EPNINKLDLVLFVSQEDELVVKRVIGLPGEFYSIEAGRVLIDAKELLENYLPKGTYTSEPSTSVFLNRHHSPFLAMDKQG
RIPPGYFLLLGDNRQYSTDSRSFGLVPVEKIKGKVIFYF

Sequences:

>Translated_199_residues
METETKGPQWWFKIKRYMRRSLYVFLFLCFLLFVRVFLFQIYSVQGNSMYPTLEHGSVVFVWKAGFAISAKFFGTELLYT
EPNINKLDLVLFVSQEDELVVKRVIGLPGEFYSIEAGRVLIDAKELLENYLPKGTYTSEPSTSVFLNRHHSPFLAMDKQG
RIPPGYFLLLGDNRQYSTDSRSFGLVPVEKIKGKVIFYF
>Mature_199_residues
METETKGPQWWFKIKRYMRRSLYVFLFLCFLLFVRVFLFQIYSVQGNSMYPTLEHGSVVFVWKAGFAISAKFFGTELLYT
EPNINKLDLVLFVSQEDELVVKRVIGLPGEFYSIEAGRVLIDAKELLENYLPKGTYTSEPSTSVFLNRHHSPFLAMDKQG
RIPPGYFLLLGDNRQYSTDSRSFGLVPVEKIKGKVIFYF

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 23116; Mature: 23116

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00501 SPASE_I_1 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METETKGPQWWFKIKRYMRRSLYVFLFLCFLLFVRVFLFQIYSVQGNSMYPTLEHGSVVF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEE
VWKAGFAISAKFFGTELLYTEPNINKLDLVLFVSQEDELVVKRVIGLPGEFYSIEAGRVL
EEECCEEEEEEECCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEECCEEE
IDAKELLENYLPKGTYTSEPSTSVFLNRHHSPFLAMDKQGRIPPGYFLLLGDNRQYSTDS
EEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCC
RSFGLVPVEKIKGKVIFYF
CCCCCEEHHHHCCEEEEEC
>Mature Secondary Structure
METETKGPQWWFKIKRYMRRSLYVFLFLCFLLFVRVFLFQIYSVQGNSMYPTLEHGSVVF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEE
VWKAGFAISAKFFGTELLYTEPNINKLDLVLFVSQEDELVVKRVIGLPGEFYSIEAGRVL
EEECCEEEEEEECCEEEEEECCCCCEEEEEEEECCCCHHHHHHHHCCCCCEEEEECCEEE
IDAKELLENYLPKGTYTSEPSTSVFLNRHHSPFLAMDKQGRIPPGYFLLLGDNRQYSTDS
EEHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEECCCCCCCCCEEEEEECCCCCCCCC
RSFGLVPVEKIKGKVIFYF
CCCCCEEHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]