BacMap

Definition	Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence.
Accession	NC_010602
Length	3,599,677

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The map label for this gene is ftsH [H]

Identifier: 183219658

GI number: 183219658

Start: 223900

End: 225852

Strand: Reverse

Name: ftsH [H]

Synonym: LEPBI_I0233

Alternate gene names: 183219658

Gene position: 225852-223900 (Counterclockwise)

Preceding gene: 183219659

Following gene: 183219657

Centisome position: 6.27

GC content: 43.63

Gene sequence:

>1953_bases
ATGAATAAAAACATCAAAACCGTATTCCTATTTTTACTCGTATTCCTTGTCATTTTGGCAACGGTTTACAAGGGCCAAGA
CTTTGCCGGTAAACCCGACGAAATCAGTTATTCCGATTTTTTGAATATGGTCGAACCCATTGAGGGGAAAAAACCCATAG
GGAAAATCACTTCCAAAGATGGGAAAGATTTATCCACAAAACAACAAATCATCATCGATAAAGAACTCATCGAAGGTTGG
TACATTCCAGAAATTAGTAAGGACAATAAACCAAAACCATTCAAAACCAACGTAGCACAGGTGAACGATGATTTGGTGAC
GAAACTTCGTAAGTCCAGACTCAGTTTCACTGCCAAGTCCACAGAAGAAAATAAATTTTGGAGTGTGGTTTCAGGCATCA
TCCCTTGGTTATTTGCACTGGGAATCATTTGGTTCATCATGATGCGCCAACTCCAAGCATCGGGTAACAAAGCATTTACG
TTTGGTAAGTCTCGTGCCAAAATGAATGTAGACCCAAAAGTCAAAGTCACATTCAATGATGTGGCGGGATGTGATGAAGC
AAAAGTAGAACTTCTCGAAATCATTGAATTCTTAAAAGACCCAAAAAAATTCCAAGCCATTGGTGCAAGGATTCCAAAGG
GCGTTCTCCTTGTGGGCCCTCCAGGAACTGGTAAAACCTTACTCGCAAAAGCAGTCGCTGGTGAAGCTGGTGTTCCTTTT
TTCTCCATCTCTGGTTCTGACTTCGTAGAAATGTTTGTGGGTGTGGGTGCATCGCGCGTGCGAGACCTCTTTGACCAAGG
AAAGAAGAATGCACCTTGTATCATTTTCATCGATGAGATTGATGCGGTAGGTCGCCTTCGTGGTGCAGGCCTCGGTGGTG
GACATGATGAAAGAGAACAAACCCTCAATCAGATGTTAGTCGAGATGGATGGATTCGAAATGAACGAAGGTGTCATTGTG
ATGGCGGCAACAAACCGCGCGGATGTCCTTGACCCAGCCCTCCTCCGACCAGGTCGTTTTGACAGACAAGTGATCGTGGA
CCTTCCTGACTTAAAAGGCCGTGAAGAGATTTTGGCCGTTCACTCCAAAAAAGTACCTTTAGTTTCTGATATTTCTCTCA
ATTCCATTGCTCGTGGGACTCCAGGTTTTACGGGAGCTGACCTTGCCAACCTGATCAATGAAGCGGCCCTCCTTGCGGCA
CGTCGTAACAAAAAACGTGTGACCCAAGAAGAACTCGAAGAAGCACGCGATAAAGTGATGATGGGACCAGAAAGAAAGTC
CATGTTCATCTCTGACAAAGAGAAAGAGATGACAGCCTACCATGAAGCAGGCCATGCCCTTCTTGGCACCTTACTGCCAT
ATACAGAACCCGTTCACAAAGTTACCATCATCCCACGTGGTCGTGCACTTGGTCTTACCCAATCCCTTCCCGTGGAAGAC
AGACATTCTTATCGTAAGAACTATTGTTTGGATCGGATTGTGATGTCTATGGGTGGATACATTGCCGAAGAACTGATCTT
TGGTGATCCTTCGAATGGTTCTTCTAATGATATCCAACAAGCAACAAACATTGCACGTCGTATGGTATGTGAATGGGGTA
TGTCTGAAAAACTAGGAACCATTCATTACGGATCTGGGGAAACTTCTCCTTTTATGGGAAGGGACTATGGTCATACAAGT
AAACCTTACTCGGAAGAATTTGCGGCAATGATTGACCAAGAAGTAAAACGTATCATACAAACTTGTCTCGACAAAGGTCG
TGACTTAGTGAAGAAAAACCAAAAAAAATTGGATGCCATTGCGAAAGCTCTTCTTGCAAAAGAAACCATTGATGCACAGG
AACTCATGGACATTGTCCAACCTTCTTTTGATAAATTCTCTGCTTCAAAATCAGGGATTGGATCCAAAAAAGGAAAAGGT
ACTTCAGCAACCAAACCAGCTTACTCGGCTTAA

Upstream 100 bases:

>100_bases
TGACGCCGAAGCGGCGATTCGTTCCATATCCATGGGGGATATTGACGAAGTGATTCAGAAATATCACCTTTGATTTTAGT
CTAATCATCGGAAGTCTTAC

Downstream 100 bases:

>100_bases
TGAAGTATTGGCTCTTTAAAACAGAACCAGATGTTTTTTCGATCGATGACCTAATCCGAGAAAAACTCTCGTATTGGGAA
GGGGTCAGAAATTACCAAGC

Product: cell division protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 650

Protein sequence:

>650_residues
MNKNIKTVFLFLLVFLVILATVYKGQDFAGKPDEISYSDFLNMVEPIEGKKPIGKITSKDGKDLSTKQQIIIDKELIEGW
YIPEISKDNKPKPFKTNVAQVNDDLVTKLRKSRLSFTAKSTEENKFWSVVSGIIPWLFALGIIWFIMMRQLQASGNKAFT
FGKSRAKMNVDPKVKVTFNDVAGCDEAKVELLEIIEFLKDPKKFQAIGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPF
FSISGSDFVEMFVGVGASRVRDLFDQGKKNAPCIIFIDEIDAVGRLRGAGLGGGHDEREQTLNQMLVEMDGFEMNEGVIV
MAATNRADVLDPALLRPGRFDRQVIVDLPDLKGREEILAVHSKKVPLVSDISLNSIARGTPGFTGADLANLINEAALLAA
RRNKKRVTQEELEEARDKVMMGPERKSMFISDKEKEMTAYHEAGHALLGTLLPYTEPVHKVTIIPRGRALGLTQSLPVED
RHSYRKNYCLDRIVMSMGGYIAEELIFGDPSNGSSNDIQQATNIARRMVCEWGMSEKLGTIHYGSGETSPFMGRDYGHTS
KPYSEEFAAMIDQEVKRIIQTCLDKGRDLVKKNQKKLDAIAKALLAKETIDAQELMDIVQPSFDKFSASKSGIGSKKGKG
TSATKPAYSA

Sequences:

>Translated_650_residues
MNKNIKTVFLFLLVFLVILATVYKGQDFAGKPDEISYSDFLNMVEPIEGKKPIGKITSKDGKDLSTKQQIIIDKELIEGW
YIPEISKDNKPKPFKTNVAQVNDDLVTKLRKSRLSFTAKSTEENKFWSVVSGIIPWLFALGIIWFIMMRQLQASGNKAFT
FGKSRAKMNVDPKVKVTFNDVAGCDEAKVELLEIIEFLKDPKKFQAIGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPF
FSISGSDFVEMFVGVGASRVRDLFDQGKKNAPCIIFIDEIDAVGRLRGAGLGGGHDEREQTLNQMLVEMDGFEMNEGVIV
MAATNRADVLDPALLRPGRFDRQVIVDLPDLKGREEILAVHSKKVPLVSDISLNSIARGTPGFTGADLANLINEAALLAA
RRNKKRVTQEELEEARDKVMMGPERKSMFISDKEKEMTAYHEAGHALLGTLLPYTEPVHKVTIIPRGRALGLTQSLPVED
RHSYRKNYCLDRIVMSMGGYIAEELIFGDPSNGSSNDIQQATNIARRMVCEWGMSEKLGTIHYGSGETSPFMGRDYGHTS
KPYSEEFAAMIDQEVKRIIQTCLDKGRDLVKKNQKKLDAIAKALLAKETIDAQELMDIVQPSFDKFSASKSGIGSKKGKG
TSATKPAYSA
>Mature_650_residues
MNKNIKTVFLFLLVFLVILATVYKGQDFAGKPDEISYSDFLNMVEPIEGKKPIGKITSKDGKDLSTKQQIIIDKELIEGW
YIPEISKDNKPKPFKTNVAQVNDDLVTKLRKSRLSFTAKSTEENKFWSVVSGIIPWLFALGIIWFIMMRQLQASGNKAFT
FGKSRAKMNVDPKVKVTFNDVAGCDEAKVELLEIIEFLKDPKKFQAIGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPF
FSISGSDFVEMFVGVGASRVRDLFDQGKKNAPCIIFIDEIDAVGRLRGAGLGGGHDEREQTLNQMLVEMDGFEMNEGVIV
MAATNRADVLDPALLRPGRFDRQVIVDLPDLKGREEILAVHSKKVPLVSDISLNSIARGTPGFTGADLANLINEAALLAA
RRNKKRVTQEELEEARDKVMMGPERKSMFISDKEKEMTAYHEAGHALLGTLLPYTEPVHKVTIIPRGRALGLTQSLPVED
RHSYRKNYCLDRIVMSMGGYIAEELIFGDPSNGSSNDIQQATNIARRMVCEWGMSEKLGTIHYGSGETSPFMGRDYGHTS
KPYSEEFAAMIDQEVKRIIQTCLDKGRDLVKKNQKKLDAIAKALLAKETIDAQELMDIVQPSFDKFSASKSGIGSKKGKG
TSATKPAYSA

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins [H]

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family [H]

Homologues:

Organism=Homo sapiens, GI300192933, Length=467, Percent_Identity=47.96573875803, Blast_Score=451, Evalue=1e-126,
Organism=Homo sapiens, GI21327685, Length=456, Percent_Identity=49.1228070175439, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI7657689, Length=456, Percent_Identity=49.1228070175439, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI4507173, Length=578, Percent_Identity=39.2733564013841, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI24497435, Length=285, Percent_Identity=42.8070175438597, Blast_Score=218, Evalue=2e-56,
Organism=Homo sapiens, GI4506209, Length=254, Percent_Identity=42.5196850393701, Blast_Score=213, Evalue=4e-55,
Organism=Homo sapiens, GI21361144, Length=253, Percent_Identity=42.2924901185771, Blast_Score=203, Evalue=4e-52,
Organism=Homo sapiens, GI24430151, Length=254, Percent_Identity=38.9763779527559, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI6005942, Length=230, Percent_Identity=46.5217391304348, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI195539395, Length=245, Percent_Identity=42.0408163265306, Blast_Score=200, Evalue=4e-51,
Organism=Homo sapiens, GI45643123, Length=278, Percent_Identity=39.568345323741, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI89064750, Length=263, Percent_Identity=39.9239543726236, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI45643125, Length=278, Percent_Identity=39.568345323741, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI5729991, Length=263, Percent_Identity=39.9239543726236, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI24430155, Length=263, Percent_Identity=39.9239543726236, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI157671927, Length=225, Percent_Identity=41.3333333333333, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI40806173, Length=270, Percent_Identity=39.6296296296296, Blast_Score=175, Evalue=9e-44,
Organism=Homo sapiens, GI229577436, Length=256, Percent_Identity=40.234375, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI4505725, Length=223, Percent_Identity=40.8071748878924, Blast_Score=169, Evalue=6e-42,
Organism=Homo sapiens, GI153792536, Length=242, Percent_Identity=39.6694214876033, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI24497618, Length=257, Percent_Identity=38.1322957198444, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI194018488, Length=255, Percent_Identity=41.1764705882353, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI5901990, Length=256, Percent_Identity=38.28125, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI14149767, Length=245, Percent_Identity=38.3673469387755, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI62177112, Length=245, Percent_Identity=38.3673469387755, Blast_Score=153, Evalue=6e-37,
Organism=Homo sapiens, GI226371754, Length=240, Percent_Identity=36.25, Blast_Score=143, Evalue=4e-34,
Organism=Homo sapiens, GI11875211, Length=268, Percent_Identity=38.8059701492537, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI40806170, Length=268, Percent_Identity=38.8059701492537, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI7019569, Length=240, Percent_Identity=36.6666666666667, Blast_Score=139, Evalue=1e-32,
Organism=Homo sapiens, GI31377644, Length=276, Percent_Identity=35.5072463768116, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI31742536, Length=226, Percent_Identity=35.8407079646018, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI112789543, Length=226, Percent_Identity=35.8407079646018, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI17865802, Length=232, Percent_Identity=37.5, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI156564401, Length=232, Percent_Identity=35.7758620689655, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI310125282, Length=232, Percent_Identity=35.3448275862069, Blast_Score=127, Evalue=5e-29,
Organism=Homo sapiens, GI310125280, Length=232, Percent_Identity=35.3448275862069, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI64084766, Length=226, Percent_Identity=28.3185840707965, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI116292174, Length=282, Percent_Identity=29.7872340425532, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1789568, Length=635, Percent_Identity=53.2283464566929, Blast_Score=610, Evalue=1e-175,
Organism=Caenorhabditis elegans, GI71994521, Length=464, Percent_Identity=48.4913793103448, Blast_Score=439, Evalue=1e-123,
Organism=Caenorhabditis elegans, GI17554264, Length=439, Percent_Identity=47.8359908883827, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115534323, Length=461, Percent_Identity=46.4208242950108, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17554786, Length=255, Percent_Identity=46.2745098039216, Blast_Score=228, Evalue=9e-60,
Organism=Caenorhabditis elegans, GI25144278, Length=255, Percent_Identity=45.8823529411765, Blast_Score=223, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI25144281, Length=255, Percent_Identity=45.8823529411765, Blast_Score=223, Evalue=3e-58,
Organism=Caenorhabditis elegans, GI17563248, Length=256, Percent_Identity=43.359375, Blast_Score=214, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17532375, Length=290, Percent_Identity=37.5862068965517, Blast_Score=208, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI17508701, Length=314, Percent_Identity=36.3057324840764, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI17563250, Length=309, Percent_Identity=37.5404530744337, Blast_Score=201, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI71987372, Length=282, Percent_Identity=37.9432624113475, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71987364, Length=282, Percent_Identity=37.9432624113475, Blast_Score=195, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=253, Percent_Identity=40.7114624505929, Blast_Score=191, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17531535, Length=268, Percent_Identity=38.8059701492537, Blast_Score=186, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17554784, Length=251, Percent_Identity=39.8406374501992, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17508053, Length=230, Percent_Identity=40.8695652173913, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17537217, Length=231, Percent_Identity=42.4242424242424, Blast_Score=169, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI133931034, Length=242, Percent_Identity=40.495867768595, Blast_Score=158, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI193206114, Length=242, Percent_Identity=40.495867768595, Blast_Score=158, Evalue=9e-39,
Organism=Caenorhabditis elegans, GI193206116, Length=242, Percent_Identity=40.495867768595, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25153574, Length=235, Percent_Identity=37.8723404255319, Blast_Score=151, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=47.2727272727273, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=47.2727272727273, Blast_Score=146, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI193209502, Length=238, Percent_Identity=37.8151260504202, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25146157, Length=235, Percent_Identity=40.8510638297872, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI17562804, Length=236, Percent_Identity=37.2881355932203, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI86561515, Length=235, Percent_Identity=36.1702127659575, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI32563584, Length=257, Percent_Identity=35.7976653696498, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17508421, Length=257, Percent_Identity=35.7976653696498, Blast_Score=128, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI133901658, Length=219, Percent_Identity=35.1598173515982, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI133901662, Length=216, Percent_Identity=35.6481481481481, Blast_Score=127, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17560432, Length=229, Percent_Identity=37.117903930131, Blast_Score=117, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17541226, Length=235, Percent_Identity=34.468085106383, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17541224, Length=235, Percent_Identity=34.468085106383, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71990294, Length=198, Percent_Identity=29.2929292929293, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323736, Length=521, Percent_Identity=47.6007677543186, Blast_Score=473, Evalue=1e-134,
Organism=Saccharomyces cerevisiae, GI6320854, Length=542, Percent_Identity=46.1254612546125, Blast_Score=458, Evalue=1e-129,
Organism=Saccharomyces cerevisiae, GI6325281, Length=512, Percent_Identity=43.75, Blast_Score=430, Evalue=1e-121,
Organism=Saccharomyces cerevisiae, GI6322704, Length=256, Percent_Identity=44.140625, Blast_Score=216, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6321390, Length=245, Percent_Identity=44.0816326530612, Blast_Score=216, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6324691, Length=270, Percent_Identity=43.3333333333333, Blast_Score=206, Evalue=1e-53,
Organism=Saccharomyces cerevisiae, GI6320077, Length=262, Percent_Identity=41.6030534351145, Blast_Score=204, Evalue=4e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=254, Percent_Identity=38.9763779527559, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324833, Length=246, Percent_Identity=42.6829268292683, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6320602, Length=252, Percent_Identity=42.0634920634921, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322994, Length=291, Percent_Identity=34.3642611683849, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324000, Length=262, Percent_Identity=39.6946564885496, Blast_Score=171, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6321709, Length=267, Percent_Identity=37.0786516853933, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322651, Length=287, Percent_Identity=35.8885017421603, Blast_Score=166, Evalue=7e-42,
Organism=Saccharomyces cerevisiae, GI6323429, Length=227, Percent_Identity=40.9691629955947, Blast_Score=163, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6325431, Length=251, Percent_Identity=37.8486055776892, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6321465, Length=240, Percent_Identity=37.9166666666667, Blast_Score=131, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=35.1851851851852, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6325183, Length=239, Percent_Identity=35.1464435146443, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320887, Length=254, Percent_Identity=34.6456692913386, Blast_Score=116, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6320583, Length=161, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24665814, Length=505, Percent_Identity=45.1485148514852, Blast_Score=451, Evalue=1e-127,
Organism=Drosophila melanogaster, GI28574878, Length=505, Percent_Identity=45.1485148514852, Blast_Score=451, Evalue=1e-127,
Organism=Drosophila melanogaster, GI24658770, Length=461, Percent_Identity=50.5422993492408, Blast_Score=432, Evalue=1e-121,
Organism=Drosophila melanogaster, GI24639391, Length=452, Percent_Identity=47.1238938053097, Blast_Score=418, Evalue=1e-117,
Organism=Drosophila melanogaster, GI19920408, Length=288, Percent_Identity=42.7083333333333, Blast_Score=219, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24651451, Length=285, Percent_Identity=43.1578947368421, Blast_Score=217, Evalue=2e-56,
Organism=Drosophila melanogaster, GI17137738, Length=254, Percent_Identity=42.9133858267717, Blast_Score=211, Evalue=1e-54,
Organism=Drosophila melanogaster, GI45554047, Length=165, Percent_Identity=60.6060606060606, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI161076486, Length=244, Percent_Identity=40.1639344262295, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17137560, Length=244, Percent_Identity=40.1639344262295, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI161076488, Length=244, Percent_Identity=40.1639344262295, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24649446, Length=309, Percent_Identity=36.2459546925566, Blast_Score=201, Evalue=2e-51,
Organism=Drosophila melanogaster, GI17738151, Length=249, Percent_Identity=40.9638554216867, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI281365776, Length=232, Percent_Identity=43.1034482758621, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24660075, Length=232, Percent_Identity=43.1034482758621, Blast_Score=194, Evalue=1e-49,
Organism=Drosophila melanogaster, GI45552965, Length=232, Percent_Identity=43.1034482758621, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24640100, Length=245, Percent_Identity=42.0408163265306, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI18860063, Length=244, Percent_Identity=40.9836065573771, Blast_Score=187, Evalue=3e-47,
Organism=Drosophila melanogaster, GI281361487, Length=265, Percent_Identity=38.1132075471698, Blast_Score=186, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24652279, Length=206, Percent_Identity=42.2330097087379, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24663015, Length=245, Percent_Identity=39.5918367346939, Blast_Score=181, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19921202, Length=227, Percent_Identity=40.5286343612335, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24656825, Length=247, Percent_Identity=39.6761133603239, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI24656820, Length=247, Percent_Identity=39.6761133603239, Blast_Score=168, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281363136, Length=239, Percent_Identity=38.0753138075314, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI78707192, Length=239, Percent_Identity=38.0753138075314, Blast_Score=150, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24644145, Length=249, Percent_Identity=36.9477911646586, Blast_Score=149, Evalue=8e-36,
Organism=Drosophila melanogaster, GI21355121, Length=212, Percent_Identity=36.7924528301887, Blast_Score=143, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281360136, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI24644411, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281360144, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281360140, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI281360142, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI21357333, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI281360146, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI281360138, Length=253, Percent_Identity=35.9683794466403, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI18859657, Length=235, Percent_Identity=37.8723404255319, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28571849, Length=234, Percent_Identity=39.3162393162393, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28571847, Length=234, Percent_Identity=39.3162393162393, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573010, Length=237, Percent_Identity=36.2869198312236, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20129529, Length=293, Percent_Identity=32.7645051194539, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI24581396, Length=234, Percent_Identity=39.3162393162393, Blast_Score=133, Evalue=5e-31,
Organism=Drosophila melanogaster, GI20129423, Length=266, Percent_Identity=33.4586466165414, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17864540, Length=240, Percent_Identity=35.4166666666667, Blast_Score=126, Evalue=6e-29,
Organism=Drosophila melanogaster, GI24639486, Length=208, Percent_Identity=36.5384615384615, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR011546
- InterPro:   IPR000642 [H]

Pfam domain/function: PF00004 AAA; PF06480 FtsH_ext; PF01434 Peptidase_M41 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 71695; Mature: 71695

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKNIKTVFLFLLVFLVILATVYKGQDFAGKPDEISYSDFLNMVEPIEGKKPIGKITSKD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GKDLSTKQQIIIDKELIEGWYIPEISKDNKPKPFKTNVAQVNDDLVTKLRKSRLSFTAKS
CCCCCCHHHHEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHEEECC
TEENKFWSVVSGIIPWLFALGIIWFIMMRQLQASGNKAFTFGKSRAKMNVDPKVKVTFND
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCEEEEEECC
VAGCDEAKVELLEIIEFLKDPKKFQAIGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPF
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCCCCCE
FSISGSDFVEMFVGVGASRVRDLFDQGKKNAPCIIFIDEIDAVGRLRGAGLGGGHDEREQ
EECCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCCCCHHHHH
TLNQMLVEMDGFEMNEGVIVMAATNRADVLDPALLRPGRFDRQVIVDLPDLKGREEILAV
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHH
HSKKVPLVSDISLNSIARGTPGFTGADLANLINEAALLAARRNKKRVTQEELEEARDKVM
HCCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
MGPERKSMFISDKEKEMTAYHEAGHALLGTLLPYTEPVHKVTIIPRGRALGLTQSLPVED
CCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCCCCCCCHH
RHSYRKNYCLDRIVMSMGGYIAEELIFGDPSNGSSNDIQQATNIARRMVCEWGMSEKLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCE
IHYGSGETSPFMGRDYGHTSKPYSEEFAAMIDQEVKRIIQTCLDKGRDLVKKNQKKLDAI
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AKALLAKETIDAQELMDIVQPSFDKFSASKSGIGSKKGKGTSATKPAYSA
HHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNKNIKTVFLFLLVFLVILATVYKGQDFAGKPDEISYSDFLNMVEPIEGKKPIGKITSKD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCC
GKDLSTKQQIIIDKELIEGWYIPEISKDNKPKPFKTNVAQVNDDLVTKLRKSRLSFTAKS
CCCCCCHHHHEEEHHHHCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHEEECC
TEENKFWSVVSGIIPWLFALGIIWFIMMRQLQASGNKAFTFGKSRAKMNVDPKVKVTFND
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEECCCCEEEEEECC
VAGCDEAKVELLEIIEFLKDPKKFQAIGARIPKGVLLVGPPGTGKTLLAKAVAGEAGVPF
CCCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHCCCCCCCE
FSISGSDFVEMFVGVGASRVRDLFDQGKKNAPCIIFIDEIDAVGRLRGAGLGGGHDEREQ
EECCCHHHHHHHHHCCHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHCCCCCCCCHHHHH
TLNQMLVEMDGFEMNEGVIVMAATNRADVLDPALLRPGRFDRQVIVDLPDLKGREEILAV
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHH
HSKKVPLVSDISLNSIARGTPGFTGADLANLINEAALLAARRNKKRVTQEELEEARDKVM
HCCCCCEEECCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
MGPERKSMFISDKEKEMTAYHEAGHALLGTLLPYTEPVHKVTIIPRGRALGLTQSLPVED
CCCCHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCEECCCCCCCCHH
RHSYRKNYCLDRIVMSMGGYIAEELIFGDPSNGSSNDIQQATNIARRMVCEWGMSEKLGT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCE
IHYGSGETSPFMGRDYGHTSKPYSEEFAAMIDQEVKRIIQTCLDKGRDLVKKNQKKLDAI
EEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
AKALLAKETIDAQELMDIVQPSFDKFSASKSGIGSKKGKGTSATKPAYSA
HHHHHHHHCCCHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA