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The map label for this gene is 18311558

Identifier: 18311558

GI number: 18311558

Start: 2952091

End: 2952708

Strand: Reverse

Name: 18311558

Synonym: CPE2576

Alternate gene names: NA

Gene position: 2952708-2952091 (Counterclockwise)

Preceding gene: 18311559

Following gene: 18311557

Centisome position: 97.4

GC content: 30.74

Gene sequence:

>618_bases
ATGAGATTAGGAAGAGATTTTTATAATAGAGATACAGTAACTGTAGCTAAAGAGCTTTTAGGAAAAGTTTTAGTTAGAAA
TATTAATGGAGTTACTTTAAAAGGAAAGATTGTGGAGACGGAAGCTTATATAGGAGCTATAGATAAAGCTTCTCATGCTT
ACGGTGGCAAGAGAACTAATAGAACAGAAACTCTTTATGCAGATCCGGGAACTGTATATGTTTATATAATTTATGGAATG
TATCACTGCTTAAATCTAATAAGTGAAGAAAAAGACGTGGCAGGAGGAGTACTTATAAGAGGAATTGAACCTTTAGAGGG
AATAGAAGAAATGAGTAAATTAAGATATAAGAAGAGTTATGAAGAGTTATCAAACTATGAAAAGAAAAATTTTTCTAATG
GTCCATCAAAATTATGCATGGCTTTAGGAATAGATAAGGGGGAGAATGGCATAAATACTATTAGTAGCGAAGAGATTTAT
GTTGAAGATGACTCCTTAATTAAAAAGGATTTTTCTATTGTTGAAGCAAAGAGAATAGGCATAGATTATGCTGAGGAAGC
TAGGGATTTTTTATGGAGATTTTATATTAAGGATAATAAATTTGTCTCTAAAAAATAA

Upstream 100 bases:

>100_bases
ATGAAACTGAGAAGTTATTGTATAGAATTATAATTAGTAAGTAAAGATAAAATTGTATAACTAATAGTTTTATAAAAGAG
AATTATAGAAGAGGTGCTTT

Downstream 100 bases:

>100_bases
TAAATAGTATTTTCTTTAAATCTTAATATAATATCTGCGCTACAATAGTTATTTTGTGGGGGAGTTTTTTATGGCTATAA
AGGATGCTAACAAGCAATAT

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MRLGRDFYNRDTVTVAKELLGKVLVRNINGVTLKGKIVETEAYIGAIDKASHAYGGKRTNRTETLYADPGTVYVYIIYGM
YHCLNLISEEKDVAGGVLIRGIEPLEGIEEMSKLRYKKSYEELSNYEKKNFSNGPSKLCMALGIDKGENGINTISSEEIY
VEDDSLIKKDFSIVEAKRIGIDYAEEARDFLWRFYIKDNKFVSKK

Sequences:

>Translated_205_residues
MRLGRDFYNRDTVTVAKELLGKVLVRNINGVTLKGKIVETEAYIGAIDKASHAYGGKRTNRTETLYADPGTVYVYIIYGM
YHCLNLISEEKDVAGGVLIRGIEPLEGIEEMSKLRYKKSYEELSNYEKKNFSNGPSKLCMALGIDKGENGINTISSEEIY
VEDDSLIKKDFSIVEAKRIGIDYAEEARDFLWRFYIKDNKFVSKK
>Mature_205_residues
MRLGRDFYNRDTVTVAKELLGKVLVRNINGVTLKGKIVETEAYIGAIDKASHAYGGKRTNRTETLYADPGTVYVYIIYGM
YHCLNLISEEKDVAGGVLIRGIEPLEGIEEMSKLRYKKSYEELSNYEKKNFSNGPSKLCMALGIDKGENGINTISSEEIY
VEDDSLIKKDFSIVEAKRIGIDYAEEARDFLWRFYIKDNKFVSKK

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=205, Percent_Identity=43.9024390243902, Blast_Score=154, Evalue=6e-38,
Organism=Homo sapiens, GI62632765, Length=205, Percent_Identity=43.9024390243902, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI62632771, Length=205, Percent_Identity=43.9024390243902, Blast_Score=153, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.-

Molecular weight: Translated: 23310; Mature: 23310

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGRDFYNRDTVTVAKELLGKVLVRNINGVTLKGKIVETEAYIGAIDKASHAYGGKRTN
CCCCCCHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCCCC
RTETLYADPGTVYVYIIYGMYHCLNLISEEKDVAGGVLIRGIEPLEGIEEMSKLRYKKSY
CCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
EELSNYEKKNFSNGPSKLCMALGIDKGENGINTISSEEIYVEDDSLIKKDFSIVEAKRIG
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHC
IDYAEEARDFLWRFYIKDNKFVSKK
CCHHHHHHHHHHHEEEECCEEECCC
>Mature Secondary Structure
MRLGRDFYNRDTVTVAKELLGKVLVRNINGVTLKGKIVETEAYIGAIDKASHAYGGKRTN
CCCCCCHHCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEHHHHHHHHHHHHHHCCCCCCC
RTETLYADPGTVYVYIIYGMYHCLNLISEEKDVAGGVLIRGIEPLEGIEEMSKLRYKKSY
CCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHH
EELSNYEKKNFSNGPSKLCMALGIDKGENGINTISSEEIYVEDDSLIKKDFSIVEAKRIG
HHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHC
IDYAEEARDFLWRFYIKDNKFVSKK
CCHHHHHHHHHHHEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA