Click here to switch to the map view.

The map label for this gene is ubiB [C]

Identifier: 18311510

GI number: 18311510

Start: 2895589

End: 2897202

Strand: Reverse

Name: ubiB [C]

Synonym: CPE2528

Alternate gene names: 18311510

Gene position: 2897202-2895589 (Counterclockwise)

Preceding gene: 18311511

Following gene: 18311509

Centisome position: 95.57

GC content: 29.49

Gene sequence:

>1614_bases
ATGAGTAAGGGACAGAGTGCAAAAAGGTTGAAAGAAATAGTTAGAGTATTTACTTATTATGGTTTTGACTTTTTAATTTC
ATCAAAATTGCCAAATAGTAAAAAGGTTGAGCCAAGGCCTCAAGCACTTAGAGAGGCTTTAGAAGAATTAGGGGCAACCT
TTGTTAAAATTGGACAAATATTGAGTACAAGGCCAGATTTACTTCCTAAAGCTTATATTGAAGAGTTGGAAAAGTTACAG
GATAATAATGAAATAACAGACTTTCATAAGGTAAAGGAAATATTTTATGAATCTTTTGGGACTGATATAAATACATATTT
CTTAGAATTTAGTGAAACTCCATTAGCTTCAGCATCAATTGCACAGGTTCATAGAGCTCAATTAATAGATGGAAGAGATG
TAGTAGTTAAGGTTCAGCATTATAAAATAGATGAAAAAATGAAGCTTGATTTAAGCATATTAAGAAGACTTAGTAAATTA
ACATCTAGTCATATAGCTAATACCTTAATTAATCCAGTTGAAGCTTTTAAGGAAATTGAAGAGGCTACCTTAAAAGAACT
TGATTTCGAAAAGGAAGCAAAGAATACTAAAAGGTTTAGAGAGCTTAATAAAAATGTAGCCTGTGTTGGAGCACCCATAA
TTATTGATAAGCTTACTTCTAAGAAAATCCTTACCATGGAATATATAGATGGTTGCAAAGTAACAGATTTTAATATTTTA
AAAGAAGAGGGATATGACTTTGAGGACATTGCAAACAAACTAGCAAATTCATTTTTTAAACAGGTATTAGAAGATGGATT
TTTCCATGGTGATCCTCATCCAGGAAATTTATTTATAAGAGAAGGCAAAATATATTTTATAGACTTTGGCTTAGTTGGAA
CTTTAGAAGCAAATTTAAGAAATTGGCTTAATAAGGCTATGATTGCTATGGTTTTAGGGGATATTGATACCTTAGTTGAT
TTTGTAAATGCCATAGGAATAAAAAAAGGAAAAGTTGAATATTCAATATTATATGATGACTTAAAAAATATAGTCTCAAA
ATATATAAATGCATCTTTAAAGACAATAAAGATATCAGATTTATTTAAAGAAATCTTTGAGATTGCAGAACGAAATAATA
TTCAATTTCCAAGAGAATTAGTTGCTTTAGTAAGATCCATAGTTATATTAGAAGGGGTCATAGCTAAAATAGATCCAGAT
TTAGAAATTATGGAATGTATTTATCCTTATGTAAAGGAAAGAAATAAAGAGGAAATGTTAAAAAGTTTAAACAAGGATAA
ACTTTTAACTGAAGCCTATAAGTTTGCTTCTAAGAGCATAGAAATTCCTACTAAATTTTCAGAACTTGTGGATAGCTTAA
CTAAGGGAAGAGCTAAGTTGCAATTTGAAATGAAGGGCTTAGATAAGCCACTTACAGATTTAAATAGAATGGTAAATAGA
GTAGCATTCTCTTTAATAGTTGGATGTATGATTATAGGTTCTTCATTAATAGTTAATGCTAAAACTGGACCTACTTTTCA
AGGGGTTCCTATTTTAGGATTAATAGGCTTTATAGTGTCAGGAATTTTTGGTTTGTGGTTATTGATTTCCATAATAAAAT
CAGGCTTTTTTTAA

Upstream 100 bases:

>100_bases
AGAATTTATAGCTATGTAAATAGCTAAGATGATTAAGCTTTTCAGTGCTTTGTAGAGTTTTTATAGTTTATTATTTTATT
ATCTTATAGGAGGTGAATTT

Downstream 100 bases:

>100_bases
TAAATGGTTAATAAAGTAATTAAATACTTGAAAGAAACATAGTTATATTGTATAAATGTATACAATATAATAATTAAAAG
TGAATAATTTAAAAAGAGGT

Product: hypothetical protein

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MSKGQSAKRLKEIVRVFTYYGFDFLISSKLPNSKKVEPRPQALREALEELGATFVKIGQILSTRPDLLPKAYIEELEKLQ
DNNEITDFHKVKEIFYESFGTDINTYFLEFSETPLASASIAQVHRAQLIDGRDVVVKVQHYKIDEKMKLDLSILRRLSKL
TSSHIANTLINPVEAFKEIEEATLKELDFEKEAKNTKRFRELNKNVACVGAPIIIDKLTSKKILTMEYIDGCKVTDFNIL
KEEGYDFEDIANKLANSFFKQVLEDGFFHGDPHPGNLFIREGKIYFIDFGLVGTLEANLRNWLNKAMIAMVLGDIDTLVD
FVNAIGIKKGKVEYSILYDDLKNIVSKYINASLKTIKISDLFKEIFEIAERNNIQFPRELVALVRSIVILEGVIAKIDPD
LEIMECIYPYVKERNKEEMLKSLNKDKLLTEAYKFASKSIEIPTKFSELVDSLTKGRAKLQFEMKGLDKPLTDLNRMVNR
VAFSLIVGCMIIGSSLIVNAKTGPTFQGVPILGLIGFIVSGIFGLWLLISIIKSGFF

Sequences:

>Translated_537_residues
MSKGQSAKRLKEIVRVFTYYGFDFLISSKLPNSKKVEPRPQALREALEELGATFVKIGQILSTRPDLLPKAYIEELEKLQ
DNNEITDFHKVKEIFYESFGTDINTYFLEFSETPLASASIAQVHRAQLIDGRDVVVKVQHYKIDEKMKLDLSILRRLSKL
TSSHIANTLINPVEAFKEIEEATLKELDFEKEAKNTKRFRELNKNVACVGAPIIIDKLTSKKILTMEYIDGCKVTDFNIL
KEEGYDFEDIANKLANSFFKQVLEDGFFHGDPHPGNLFIREGKIYFIDFGLVGTLEANLRNWLNKAMIAMVLGDIDTLVD
FVNAIGIKKGKVEYSILYDDLKNIVSKYINASLKTIKISDLFKEIFEIAERNNIQFPRELVALVRSIVILEGVIAKIDPD
LEIMECIYPYVKERNKEEMLKSLNKDKLLTEAYKFASKSIEIPTKFSELVDSLTKGRAKLQFEMKGLDKPLTDLNRMVNR
VAFSLIVGCMIIGSSLIVNAKTGPTFQGVPILGLIGFIVSGIFGLWLLISIIKSGFF
>Mature_536_residues
SKGQSAKRLKEIVRVFTYYGFDFLISSKLPNSKKVEPRPQALREALEELGATFVKIGQILSTRPDLLPKAYIEELEKLQD
NNEITDFHKVKEIFYESFGTDINTYFLEFSETPLASASIAQVHRAQLIDGRDVVVKVQHYKIDEKMKLDLSILRRLSKLT
SSHIANTLINPVEAFKEIEEATLKELDFEKEAKNTKRFRELNKNVACVGAPIIIDKLTSKKILTMEYIDGCKVTDFNILK
EEGYDFEDIANKLANSFFKQVLEDGFFHGDPHPGNLFIREGKIYFIDFGLVGTLEANLRNWLNKAMIAMVLGDIDTLVDF
VNAIGIKKGKVEYSILYDDLKNIVSKYINASLKTIKISDLFKEIFEIAERNNIQFPRELVALVRSIVILEGVIAKIDPDL
EIMECIYPYVKERNKEEMLKSLNKDKLLTEAYKFASKSIEIPTKFSELVDSLTKGRAKLQFEMKGLDKPLTDLNRMVNRV
AFSLIVGCMIIGSSLIVNAKTGPTFQGVPILGLIGFIVSGIFGLWLLISIIKSGFF

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI41393593, Length=346, Percent_Identity=31.5028901734104, Blast_Score=158, Evalue=1e-38,
Organism=Homo sapiens, GI40254938, Length=286, Percent_Identity=29.020979020979, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI217035081, Length=242, Percent_Identity=28.9256198347107, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI34147522, Length=243, Percent_Identity=25.1028806584362, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI27363457, Length=239, Percent_Identity=23.0125523012552, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI217416386, Length=217, Percent_Identity=23.0414746543779, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI2367309, Length=564, Percent_Identity=27.8368794326241, Blast_Score=179, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17559152, Length=378, Percent_Identity=27.2486772486773, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32565180, Length=294, Percent_Identity=29.5918367346939, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17555620, Length=294, Percent_Identity=27.2108843537415, Blast_Score=85, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323282, Length=248, Percent_Identity=31.4516129032258, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6325148, Length=265, Percent_Identity=28.6792452830189, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6321319, Length=244, Percent_Identity=28.6885245901639, Blast_Score=90, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24662575, Length=283, Percent_Identity=30.3886925795053, Blast_Score=139, Evalue=5e-33,
Organism=Drosophila melanogaster, GI22024280, Length=291, Percent_Identity=28.1786941580756, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI18859849, Length=241, Percent_Identity=26.1410788381743, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 60950; Mature: 60819

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGQSAKRLKEIVRVFTYYGFDFLISSKLPNSKKVEPRPQALREALEELGATFVKIGQI
CCCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSTRPDLLPKAYIEELEKLQDNNEITDFHKVKEIFYESFGTDINTYFLEFSETPLASASI
HHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHH
AQVHRAQLIDGRDVVVKVQHYKIDEKMKLDLSILRRLSKLTSSHIANTLINPVEAFKEIE
HHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EATLKELDFEKEAKNTKRFRELNKNVACVGAPIIIDKLTSKKILTMEYIDGCKVTDFNIL
HHHHHHCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCEEEHHHCCCCCCCCHHHH
KEEGYDFEDIANKLANSFFKQVLEDGFFHGDPHPGNLFIREGKIYFIDFGLVGTLEANLR
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEECCCHHHHHHHHH
NWLNKAMIAMVLGDIDTLVDFVNAIGIKKGKVEYSILYDDLKNIVSKYINASLKTIKISD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCHHHEEEHHH
LFKEIFEIAERNNIQFPRELVALVRSIVILEGVIAKIDPDLEIMECIYPYVKERNKEEML
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHH
KSLNKDKLLTEAYKFASKSIEIPTKFSELVDSLTKGRAKLQFEMKGLDKPLTDLNRMVNR
HHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHEEEEEHHCCCCCHHHHHHHHHH
VAFSLIVGCMIIGSSLIVNAKTGPTFQGVPILGLIGFIVSGIFGLWLLISIIKSGFF
HHHHHHHHHHHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SKGQSAKRLKEIVRVFTYYGFDFLISSKLPNSKKVEPRPQALREALEELGATFVKIGQI
CCCCHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LSTRPDLLPKAYIEELEKLQDNNEITDFHKVKEIFYESFGTDINTYFLEFSETPLASASI
HHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCHHHH
AQVHRAQLIDGRDVVVKVQHYKIDEKMKLDLSILRRLSKLTSSHIANTLINPVEAFKEIE
HHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EATLKELDFEKEAKNTKRFRELNKNVACVGAPIIIDKLTSKKILTMEYIDGCKVTDFNIL
HHHHHHCCCHHHHHHHHHHHHHCCCCEEECCHHHHHHHCCCCEEEHHHCCCCCCCCHHHH
KEEGYDFEDIANKLANSFFKQVLEDGFFHGDPHPGNLFIREGKIYFIDFGLVGTLEANLR
HHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCEEEEEECCCHHHHHHHHH
NWLNKAMIAMVLGDIDTLVDFVNAIGIKKGKVEYSILYDDLKNIVSKYINASLKTIKISD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHCCHHHEEEHHH
LFKEIFEIAERNNIQFPRELVALVRSIVILEGVIAKIDPDLEIMECIYPYVKERNKEEML
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHH
KSLNKDKLLTEAYKFASKSIEIPTKFSELVDSLTKGRAKLQFEMKGLDKPLTDLNRMVNR
HHCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHEEEEEHHCCCCCHHHHHHHHHH
VAFSLIVGCMIIGSSLIVNAKTGPTFQGVPILGLIGFIVSGIFGLWLLISIIKSGFF
HHHHHHHHHHHHCCHHEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA