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The map label for this gene is mrp

Identifier: 18311494

GI number: 18311494

Start: 2876762

End: 2877616

Strand: Reverse

Name: mrp

Synonym: CPE2512

Alternate gene names: 18311494

Gene position: 2877616-2876762 (Counterclockwise)

Preceding gene: 18311495

Following gene: 18311493

Centisome position: 94.93

GC content: 33.22

Gene sequence:

>855_bases
ATGGGAAGTTGTGCAAGTTGTGCAAATAAAGACAAATGTAGTTCAGCTAGTAAAGATGGAGGATGTAGTTCATCAGTACC
AGCAAAATTAGGAACTAACTACGGAAATATTAAAAATGTTATAGGTGTTATAAGTGGTAAAGGTGGAGTTGGTAAATCAA
CTGTTACTGGAATATTAGCTACTCAATTAGCTAAAAAAGGCTATAAAGTTGGAGTATTAGATGCTGATATAACAGGACCA
TCAATGCCAAGATTCTTTGGGATAAATGAAAAAAGAGCAGATATAGTTGCCATGGACAGTGAAGGTAAGCAAGTTAAATT
TGTTCCAGTAAAAACTGAGCTAGGAATAAAAGTTATATCAATGAACTTACTTATGGAAGTTGAAGATGATCCTGTAATTT
GGAGAGGCCCAATGGTTACAGGAGTATTAAACCAAATGTTTAAAGATACTGATTGGGAAGAGTTAGACTACTTATTAATA
GATATGCCACCAGGAACAAGTGACATAACATTAACAGTAATGCAAACATTCCCTATAAAGGAATTAGTAATAGTTTCAAC
ACCTCAAGACATGGTATCAATGATAGTTAAAAAACTAGTTACTATGGCTCACAAAATGAATGTTTGTGTAAGAGGAGTAG
TTGAAAATATGGCTTACATAGAGTGTGAGTGTGGTAAGAAGATGAGAGTATTTAGCAAGAAATCTTCAGAAGAGCATGCT
GAATATTTAGGACTTCCTCTAATAGGAGAATTACCAATAAACTTAGACTTAACTGAAGCTTTAGAAAATGGAAAAGCTGA
AGAATATGTGGCTGAAAATCCATTATATTCATTAATCTTTGAAGGATTATATTAG

Upstream 100 bases:

>100_bases
TAGATGGAGTTTATAAGAACTCTTGGGACATCAATGTTTATGATAGTTGGAAAGATGTTCAAAAGGAATGGGATAGATAA
CAGAATGGAGGATTTTTCTT

Downstream 100 bases:

>100_bases
TATAAATAAAAGAATGGACCAAAATAGTTATATTATTTTGGTTCATTCTTTTTTATTTTTTTAATTAAGTTTATTTATAA
AGTAATATAAATTAAAATTT

Product: Mrp protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MGSCASCANKDKCSSASKDGGCSSSVPAKLGTNYGNIKNVIGVISGKGGVGKSTVTGILATQLAKKGYKVGVLDADITGP
SMPRFFGINEKRADIVAMDSEGKQVKFVPVKTELGIKVISMNLLMEVEDDPVIWRGPMVTGVLNQMFKDTDWEELDYLLI
DMPPGTSDITLTVMQTFPIKELVIVSTPQDMVSMIVKKLVTMAHKMNVCVRGVVENMAYIECECGKKMRVFSKKSSEEHA
EYLGLPLIGELPINLDLTEALENGKAEEYVAENPLYSLIFEGLY

Sequences:

>Translated_284_residues
MGSCASCANKDKCSSASKDGGCSSSVPAKLGTNYGNIKNVIGVISGKGGVGKSTVTGILATQLAKKGYKVGVLDADITGP
SMPRFFGINEKRADIVAMDSEGKQVKFVPVKTELGIKVISMNLLMEVEDDPVIWRGPMVTGVLNQMFKDTDWEELDYLLI
DMPPGTSDITLTVMQTFPIKELVIVSTPQDMVSMIVKKLVTMAHKMNVCVRGVVENMAYIECECGKKMRVFSKKSSEEHA
EYLGLPLIGELPINLDLTEALENGKAEEYVAENPLYSLIFEGLY
>Mature_283_residues
GSCASCANKDKCSSASKDGGCSSSVPAKLGTNYGNIKNVIGVISGKGGVGKSTVTGILATQLAKKGYKVGVLDADITGPS
MPRFFGINEKRADIVAMDSEGKQVKFVPVKTELGIKVISMNLLMEVEDDPVIWRGPMVTGVLNQMFKDTDWEELDYLLID
MPPGTSDITLTVMQTFPIKELVIVSTPQDMVSMIVKKLVTMAHKMNVCVRGVVENMAYIECECGKKMRVFSKKSSEEHAE
YLGLPLIGELPINLDLTEALENGKAEEYVAENPLYSLIFEGLY

Specific function: Not Known. [C]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mrp/NBP35 ATP-binding proteins family

Homologues:

Organism=Homo sapiens, GI6912540, Length=246, Percent_Identity=36.5853658536585, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI157384956, Length=232, Percent_Identity=38.7931034482759, Blast_Score=161, Evalue=5e-40,
Organism=Homo sapiens, GI118572611, Length=276, Percent_Identity=34.7826086956522, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI87082045, Length=229, Percent_Identity=41.0480349344978, Blast_Score=166, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI25143050, Length=283, Percent_Identity=37.8091872791519, Blast_Score=169, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6322188, Length=242, Percent_Identity=37.603305785124, Blast_Score=163, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6321347, Length=271, Percent_Identity=31.7343173431734, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24667611, Length=226, Percent_Identity=42.4778761061947, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI221511043, Length=248, Percent_Identity=36.6935483870968, Blast_Score=142, Evalue=2e-34,
Organism=Drosophila melanogaster, GI19921440, Length=277, Percent_Identity=34.6570397111913, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRP_CLOPE (P53381)

Other databases:

- EMBL:   BA000016
- EMBL:   X86509
- RefSeq:   NP_563428.1
- ProteinModelPortal:   P53381
- SMR:   P53381
- GeneID:   990890
- GenomeReviews:   BA000016_GR
- KEGG:   cpe:CPE2512
- NMPDR:   fig|195102.1.peg.2575
- HOGENOM:   HBG586485
- OMA:   VRRAINF
- ProtClustDB:   CLSK883345
- BioCyc:   CPER195102:CPE2512-MONOMER
- InterPro:   IPR019591
- InterPro:   IPR015223
- InterPro:   IPR000808

Pfam domain/function: PF09140 MipZ; PF10609 ParA

EC number: NA

Molecular weight: Translated: 30835; Mature: 30704

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01215 MRP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSCASCANKDKCSSASKDGGCSSSVPAKLGTNYGNIKNVIGVISGKGGVGKSTVTGILA
CCCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCHHHHHEEEECCCCCCHHHHHHHHH
TQLAKKGYKVGVLDADITGPSMPRFFGINEKRADIVAMDSEGKQVKFVPVKTELGIKVIS
HHHHHCCCEEEEEECCCCCCCCCCEECCCCCCCEEEEECCCCCEEEEEEEECCCCEEEEE
MNLLMEVEDDPVIWRGPMVTGVLNQMFKDTDWEELDYLLIDMPPGTSDITLTVMQTFPIK
EEEEEEECCCCEEEECCHHHHHHHHHHCCCCHHHCCEEEEECCCCCCCEEEEEEEECCCE
ELVIVSTPQDMVSMIVKKLVTMAHKMNVCVRGVVENMAYIECECGKKMRVFSKKSSEEHA
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEHHCCCCHHHH
EYLGLPLIGELPINLDLTEALENGKAEEYVAENPLYSLIFEGLY
HHCCCCEECCCCCCCCHHHHHHCCCCHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure 
GSCASCANKDKCSSASKDGGCSSSVPAKLGTNYGNIKNVIGVISGKGGVGKSTVTGILA
CCCCCCCCCHHCCCCCCCCCCCCCCCHHHCCCCCCHHHHHEEEECCCCCCHHHHHHHHH
TQLAKKGYKVGVLDADITGPSMPRFFGINEKRADIVAMDSEGKQVKFVPVKTELGIKVIS
HHHHHCCCEEEEEECCCCCCCCCCEECCCCCCCEEEEECCCCCEEEEEEEECCCCEEEEE
MNLLMEVEDDPVIWRGPMVTGVLNQMFKDTDWEELDYLLIDMPPGTSDITLTVMQTFPIK
EEEEEEECCCCEEEECCHHHHHHHHHHCCCCHHHCCEEEEECCCCCCCEEEEEEEECCCE
ELVIVSTPQDMVSMIVKKLVTMAHKMNVCVRGVVENMAYIECECGKKMRVFSKKSSEEHA
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEHHCCCCHHHH
EYLGLPLIGELPINLDLTEALENGKAEEYVAENPLYSLIFEGLY
HHCCCCEECCCCCCCCHHHHHHCCCCHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11792842; 7559358