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The map label for this gene is cpdC [H]

Identifier: 18311144

GI number: 18311144

Start: 2477982

End: 2480159

Strand: Reverse

Name: cpdC [H]

Synonym: CPE2162

Alternate gene names: 18311144

Gene position: 2480159-2477982 (Counterclockwise)

Preceding gene: 18311145

Following gene: 18311143

Centisome position: 81.81

GC content: 27.92

Gene sequence:

>2178_bases
GTGAGAAAACTAATTAAACCATTAAGTGTAGCTACAATGATGTTCTTATCATTAAATTTATGTTTTTTTAATGGTAAGAT
TGTTAAGGGGGAAGAGATTTCTAATGAAACTAAGGTTACCATCTTAGGAACCTCAGATATACATGGAAGATTTGTTCCTT
GGGAATATTCATCAGATACTGAAAATAAATCAGGAAGTTTATCACAAATATCAACAATTGTTAAAAAGGAGAGAAATGAA
AATCCAAATTTAATTCTTGTAGATGCAGGTGATTCAATTCAAGATAACTTTGTTGAAACTTTTAATAAAGGACCTCACCA
ACCTATGGTTTTAGGTATGAATAAGATGAAATATGATGTTTGGGAAATGGGAAACCATGAATTTAATTTTGGATTAGATG
TGCTTAAACATGTAACAAGTCAATTTGAAGGAAAGGTCTTAGCTGGTAATATCTATAATGATGATGGAACAAGATTTATG
GATGGATATACTATTATAGAAAGAGATGGTATAAAGATAGGTATTATAGGTATGGATACTCCAATGATAAAAGAGTTTGA
AAAACCATATAATATAAAAGGAATTGAATTTAGAGATCCAGTTAAAGAAACAAAAAAGATTATAAAAGAATTAGATGGAA
AAGTTGATGCCATGATTGGAGTTATGCATATGGGATTAGATAATGAAAATGCTATTTCTAATACAGGTGTTACAGATATT
GCCAATCAGTGCCCAGAGCTTACAGCAATTGTAGGGGGACACATGCATAAGTTAGTTAAAAATGAGGTTGTAAATGGAGT
TATTATAACTGAGCCAGGAAAGTATGGACAAGCTGTATCAAAAATAGATTTAACATTTAAAAAAGAAAATGGAAAAAATG
TACTTAAAAATAAAAATGCAGATACTATTTCAGTAGCTAATGTAGAATCAGATAAAGAAATAGAAGATTTATTAAAACCT
TTCCATGAGGAATTGCGTAAAGATGCTAACTCAGTTATTGGAAGACTTGAAGGGGTTAACATGGTAGATGAAGATTACAT
AAAAGGAATACCTACTATACATATAGAAGATACTCCATTAATTGATTTCTTTCATGAAGTAGGAAAATATTATAGTAAAG
CAGATGTAATAGCTTTATCTATAGATAATGATAAGGCTAAGTTAAATGTAGGAGATATAAAAAAGAAAGATATAGCTTAT
AACTATAGATATACTGGTGGAGAAATAAGCGTTTATGAAGTAACTGGAAAAGACTTAAAAAAATATATGGAATGGGCAGC
TGGCTATTTTAATACATTAAATCCAGGAGATATTACTCCAAGTTTTAATCCTAAAAGAAGAGCGTCAAAGTATAGTACTA
ATGATATGTTTGGAGGAATAACTTACAAAATTGATTTACGAGAAAAAGAAGGTAATAGGATTAAAGATGTTAAGTATAAA
GATGGAAGAGAACTTAAGGATACAGATGTTTTAAAGTTAGGAATGAATTCATATAGACTTGGACAATTACAAGGAAAAGG
AGGAATCTTTGAAGGAAAAGAATTTAAAAAACTTTGGGATTCTAAGACAGCTTATGGAGAAGAAGAAGGAACAATAAGAA
ATTTAGCTATAGACTATATTAAAAATGTTAAAAATGGCCTTATAAATACAAAAAAACAAAATAATTGGTGTCTATTAGGA
ATAGATCCAAATTCAGAAAACTATAAAAAGGTTAGAGATTTAGTTAATTCAGGAGAATTAAAAATACCTACATCAGAAGA
CGGAAAATATACTAATATAGCATCAATAAATGAAAAAGATTTACCTTCAGATAATAATACATCTAAAGAAAATGAGGAAA
ATATAAACTTAGATTCTATTAATAATAAAAATAATAATAAGGATCAAGAAGTTAATGAAGAAAGTAAAAAAGATGTGCCT
AAAGTAGAGGAAAACATAGAAAAACAAAAAAATAATAAAGAAAATAATTCAAATGGAGATAATACTTTAGTTAAAGAAGA
TAGTAAATCTAAAGAAGTGAATGAAAAAAATAATGAACAAAATAACATTGAGGAAGTTTCTAAAAAAGAAAATAAACTTC
CTAACACAGGATCTCCTATAGGTGCAGAAGCTATGTCACAAATAGGTATGTTATTATTAGGTGCAGGTGTAATATTAAAA
AAGAAAAATAAAAAATAG

Upstream 100 bases:

>100_bases
TATTCTGAAAACATGTAAATTATATATAAATATTGTAAACAATTTCAGAACAATGTATAATGTTAAGGGTAAAGTTTAAA
ATTTAGGGGGATGAAAAATA

Downstream 100 bases:

>100_bases
ATGCTACTTGGAATAAAGTGGTTAATAATCCTTCTATTTCATAGGTTTATAATCTGAATTATGGTTAATATAATAGTGTA
AGCAAGAGATAAACAAATTT

Product: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase

Products: NA

Alternate protein names: 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase; 5'-nucleotidase [H]

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MRKLIKPLSVATMMFLSLNLCFFNGKIVKGEEISNETKVTILGTSDIHGRFVPWEYSSDTENKSGSLSQISTIVKKERNE
NPNLILVDAGDSIQDNFVETFNKGPHQPMVLGMNKMKYDVWEMGNHEFNFGLDVLKHVTSQFEGKVLAGNIYNDDGTRFM
DGYTIIERDGIKIGIIGMDTPMIKEFEKPYNIKGIEFRDPVKETKKIIKELDGKVDAMIGVMHMGLDNENAISNTGVTDI
ANQCPELTAIVGGHMHKLVKNEVVNGVIITEPGKYGQAVSKIDLTFKKENGKNVLKNKNADTISVANVESDKEIEDLLKP
FHEELRKDANSVIGRLEGVNMVDEDYIKGIPTIHIEDTPLIDFFHEVGKYYSKADVIALSIDNDKAKLNVGDIKKKDIAY
NYRYTGGEISVYEVTGKDLKKYMEWAAGYFNTLNPGDITPSFNPKRRASKYSTNDMFGGITYKIDLREKEGNRIKDVKYK
DGRELKDTDVLKLGMNSYRLGQLQGKGGIFEGKEFKKLWDSKTAYGEEEGTIRNLAIDYIKNVKNGLINTKKQNNWCLLG
IDPNSENYKKVRDLVNSGELKIPTSEDGKYTNIASINEKDLPSDNNTSKENEENINLDSINNKNNNKDQEVNEESKKDVP
KVEENIEKQKNNKENNSNGDNTLVKEDSKSKEVNEKNNEQNNIEEVSKKENKLPNTGSPIGAEAMSQIGMLLLGAGVILK
KKNKK

Sequences:

>Translated_725_residues
MRKLIKPLSVATMMFLSLNLCFFNGKIVKGEEISNETKVTILGTSDIHGRFVPWEYSSDTENKSGSLSQISTIVKKERNE
NPNLILVDAGDSIQDNFVETFNKGPHQPMVLGMNKMKYDVWEMGNHEFNFGLDVLKHVTSQFEGKVLAGNIYNDDGTRFM
DGYTIIERDGIKIGIIGMDTPMIKEFEKPYNIKGIEFRDPVKETKKIIKELDGKVDAMIGVMHMGLDNENAISNTGVTDI
ANQCPELTAIVGGHMHKLVKNEVVNGVIITEPGKYGQAVSKIDLTFKKENGKNVLKNKNADTISVANVESDKEIEDLLKP
FHEELRKDANSVIGRLEGVNMVDEDYIKGIPTIHIEDTPLIDFFHEVGKYYSKADVIALSIDNDKAKLNVGDIKKKDIAY
NYRYTGGEISVYEVTGKDLKKYMEWAAGYFNTLNPGDITPSFNPKRRASKYSTNDMFGGITYKIDLREKEGNRIKDVKYK
DGRELKDTDVLKLGMNSYRLGQLQGKGGIFEGKEFKKLWDSKTAYGEEEGTIRNLAIDYIKNVKNGLINTKKQNNWCLLG
IDPNSENYKKVRDLVNSGELKIPTSEDGKYTNIASINEKDLPSDNNTSKENEENINLDSINNKNNNKDQEVNEESKKDVP
KVEENIEKQKNNKENNSNGDNTLVKEDSKSKEVNEKNNEQNNIEEVSKKENKLPNTGSPIGAEAMSQIGMLLLGAGVILK
KKNKK
>Mature_725_residues
MRKLIKPLSVATMMFLSLNLCFFNGKIVKGEEISNETKVTILGTSDIHGRFVPWEYSSDTENKSGSLSQISTIVKKERNE
NPNLILVDAGDSIQDNFVETFNKGPHQPMVLGMNKMKYDVWEMGNHEFNFGLDVLKHVTSQFEGKVLAGNIYNDDGTRFM
DGYTIIERDGIKIGIIGMDTPMIKEFEKPYNIKGIEFRDPVKETKKIIKELDGKVDAMIGVMHMGLDNENAISNTGVTDI
ANQCPELTAIVGGHMHKLVKNEVVNGVIITEPGKYGQAVSKIDLTFKKENGKNVLKNKNADTISVANVESDKEIEDLLKP
FHEELRKDANSVIGRLEGVNMVDEDYIKGIPTIHIEDTPLIDFFHEVGKYYSKADVIALSIDNDKAKLNVGDIKKKDIAY
NYRYTGGEISVYEVTGKDLKKYMEWAAGYFNTLNPGDITPSFNPKRRASKYSTNDMFGGITYKIDLREKEGNRIKDVKYK
DGRELKDTDVLKLGMNSYRLGQLQGKGGIFEGKEFKKLWDSKTAYGEEEGTIRNLAIDYIKNVKNGLINTKKQNNWCLLG
IDPNSENYKKVRDLVNSGELKIPTSEDGKYTNIASINEKDLPSDNNTSKENEENINLDSINNKNNNKDQEVNEESKKDVP
KVEENIEKQKNNKENNSNGDNTLVKEDSKSKEVNEKNNEQNNIEEVSKKENKLPNTGSPIGAEAMSQIGMLLLGAGVILK
KKNKK

Specific function: Catalyzes the release of inorganic phosphate from 2',3'- cyclic nucleotides through consecutive 2',3'-phosphodiesterase and 3'- (or 2') nucleotidase activities. Also possesses a 5'- nucleotidase activity. Does not catalyze the release of inorganic phospha

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Escherichia coli, GI1790658, Length=596, Percent_Identity=23.993288590604, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1786687, Length=435, Percent_Identity=26.6666666666667, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI19922444, Length=355, Percent_Identity=24.7887323943662, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24641187, Length=485, Percent_Identity=23.5051546391753, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19921980, Length=489, Percent_Identity=23.3128834355828, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24652512, Length=489, Percent_Identity=23.3128834355828, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI161076508, Length=489, Percent_Identity=23.3128834355828, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573524, Length=335, Percent_Identity=24.1791044776119, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19922446, Length=343, Percent_Identity=23.9067055393586, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654424, Length=343, Percent_Identity=23.9067055393586, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR019931
- InterPro:   IPR004843
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.6; =3.1.4.16; =3.1.3.5 [H]

Molecular weight: Translated: 81512; Mature: 81512

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLIKPLSVATMMFLSLNLCFFNGKIVKGEEISNETKVTILGTSDIHGRFVPWEYSSDT
CCHHHHHHHHHHHHHHHHHEEEECCEEEECCCCCCCCEEEEEECCCCCCCEECCCCCCCC
ENKSGSLSQISTIVKKERNENPNLILVDAGDSIQDNFVETFNKGPHQPMVLGMNKMKYDV
CCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEECCCHHEEHH
WEMGNHEFNFGLDVLKHVTSQFEGKVLAGNIYNDDGTRFMDGYTIIERDGIKIGIIGMDT
HHCCCCCCCHHHHHHHHHHHHHCCEEEECEEECCCCCEEECCEEEEEECCEEEEEEECCC
PMIKEFEKPYNIKGIEFRDPVKETKKIIKELDGKVDAMIGVMHMGLDNENAISNTGVTDI
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHH
ANQCPELTAIVGGHMHKLVKNEVVNGVIITEPGKYGQAVSKIDLTFKKENGKNVLKNKNA
HHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHCHHHHEEEEEECCCCCHHHHCCCC
DTISVANVESDKEIEDLLKPFHEELRKDANSVIGRLEGVNMVDEDYIKGIPTIHIEDTPL
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCH
IDFFHEVGKYYSKADVIALSIDNDKAKLNVGDIKKKDIAYNYRYTGGEISVYEVTGKDLK
HHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEECCEEEEEEECCHHHH
KYMEWAAGYFNTLNPGDITPSFNPKRRASKYSTNDMFGGITYKIDLREKEGNRIKDVKYK
HHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEEEECCCCCEECCCCC
DGRELKDTDVLKLGMNSYRLGQLQGKGGIFEGKEFKKLWDSKTAYGEEEGTIRNLAIDYI
CCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KNVKNGLINTKKQNNWCLLGIDPNSENYKKVRDLVNSGELKIPTSEDGKYTNIASINEKD
HHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCEEEEECCCCCC
LPSDNNTSKENEENINLDSINNKNNNKDQEVNEESKKDVPKVEENIEKQKNNKENNSNGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHCCCHHHHHHHHHHCCCCCCCCCC
NTLVKEDSKSKEVNEKNNEQNNIEEVSKKENKLPNTGSPIGAEAMSQIGMLLLGAGVILK
CCEEECCCCCHHCHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
KKNKK
ECCCC
>Mature Secondary Structure
MRKLIKPLSVATMMFLSLNLCFFNGKIVKGEEISNETKVTILGTSDIHGRFVPWEYSSDT
CCHHHHHHHHHHHHHHHHHEEEECCEEEECCCCCCCCEEEEEECCCCCCCEECCCCCCCC
ENKSGSLSQISTIVKKERNENPNLILVDAGDSIQDNFVETFNKGPHQPMVLGMNKMKYDV
CCCCCCHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCEEECCCHHEEHH
WEMGNHEFNFGLDVLKHVTSQFEGKVLAGNIYNDDGTRFMDGYTIIERDGIKIGIIGMDT
HHCCCCCCCHHHHHHHHHHHHHCCEEEECEEECCCCCEEECCEEEEEECCEEEEEEECCC
PMIKEFEKPYNIKGIEFRDPVKETKKIIKELDGKVDAMIGVMHMGLDNENAISNTGVTDI
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCHHHH
ANQCPELTAIVGGHMHKLVKNEVVNGVIITEPGKYGQAVSKIDLTFKKENGKNVLKNKNA
HHCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHCHHHHEEEEEECCCCCHHHHCCCC
DTISVANVESDKEIEDLLKPFHEELRKDANSVIGRLEGVNMVDEDYIKGIPTIHIEDTPL
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEECCCCH
IDFFHEVGKYYSKADVIALSIDNDKAKLNVGDIKKKDIAYNYRYTGGEISVYEVTGKDLK
HHHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCCCEEEEEEEECCEEEEEEECCHHHH
KYMEWAAGYFNTLNPGDITPSFNPKRRASKYSTNDMFGGITYKIDLREKEGNRIKDVKYK
HHHHHHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEEEECCCCCEECCCCC
DGRELKDTDVLKLGMNSYRLGQLQGKGGIFEGKEFKKLWDSKTAYGEEEGTIRNLAIDYI
CCCCCCCCHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KNVKNGLINTKKQNNWCLLGIDPNSENYKKVRDLVNSGELKIPTSEDGKYTNIASINEKD
HHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCEEEEECCCCCC
LPSDNNTSKENEENINLDSINNKNNNKDQEVNEESKKDVPKVEENIEKQKNNKENNSNGD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCHHHHHCCCHHHHHHHHHHCCCCCCCCCC
NTLVKEDSKSKEVNEKNNEQNNIEEVSKKENKLPNTGSPIGAEAMSQIGMLLLGAGVILK
CCEEECCCCCHHCHHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCEEEE
KKNKK
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]