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The map label for this gene is mreC [H]

Identifier: 18311124

GI number: 18311124

Start: 2453680

End: 2454531

Strand: Reverse

Name: mreC [H]

Synonym: CPE2142

Alternate gene names: 18311124

Gene position: 2454531-2453680 (Counterclockwise)

Preceding gene: 18311125

Following gene: 18311123

Centisome position: 80.97

GC content: 30.28

Gene sequence:

>852_bases
ATGAAATTCTTCAAGAATAAACTGGCAGTAACTGTTATAGTACTGTCAGTTGCCTTTTTAGGAATAATTATATTTACTGT
TAAGAGTGATTCTAAAAATCCAATTTCAGGTGGAGTTGGTACTGTTTTAAACCCTGTGCAGAAGGTTGTATACACAATAA
GTGATAAAGTTCATGATGTCTTTGATTTCTTCTATAATTTTTCAGATGTTAAGAATGAAAATAATGATTTAAAAAAGAAA
AATTTAGAATTAGAAAATCAATTAGTTGAATACAATGAGTTAAAGCGTCAAAATGATGTTTTAAGAGGAATAGTTGATTT
TTCTAAGGAAAATAATCAATATAAATATATCGGTACAAACATAATAGGAAAAAGCGGAAATAGCTTTGTAGAAGGTTACA
CTATTGATAAAGGATCAAGTGAAGGGATTAAAAAAGATTACATAGTGATTTCTCCAGAAGGATTAGTGGGAGTTGTAACA
GAAGTTCACTCAAACTGGTCAAAAATACAGACTTTATTAAATGAAAACGTAGCTGTTGCGGCAACTATTGAAGGAGATAG
CAATTCAGGAGACGGAATAGTTAAAGGATATAGAAATGGTAGTGAGATGCAAGCAGAGATAACTAACTTACCTATGAATT
CTACAATAAAAGAAGGTGAGACAGTAGTTACTTCAGGCCTTGGAGGATATTATCCTAAAGGAATAAGAATTGGTGAAGTA
ACATCAGTACAATCAGATGATGTTAAAGTTATGAAAACCGCTATATTAAAAACATATGTTGATTTTAATAATTTACAAGA
ATTATTTGTAGTTGTACCACCATCAGAGAGAGATGGTATAGTTAAGTATTAG

Upstream 100 bases:

>100_bases
TGTTCATATAGCAGAATCACCTCTTGACTGTGTTGCACTAGGTACAGGAAAAGCTTTAGATAAGTTTGATTTAATAGTTA
AACAACAAAGAGGATAGAAT

Downstream 100 bases:

>100_bases
AAAAGAGGGAGTAAAGTGAAAAGATTAATACTAATATTAATATGTCTTTTACTATTTATAGTAGATAATACTCTGGTACC
TTTTTTCTCTATAAAAGGTG

Product: rod shape-determining protein MreC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKFFKNKLAVTVIVLSVAFLGIIIFTVKSDSKNPISGGVGTVLNPVQKVVYTISDKVHDVFDFFYNFSDVKNENNDLKKK
NLELENQLVEYNELKRQNDVLRGIVDFSKENNQYKYIGTNIIGKSGNSFVEGYTIDKGSSEGIKKDYIVISPEGLVGVVT
EVHSNWSKIQTLLNENVAVAATIEGDSNSGDGIVKGYRNGSEMQAEITNLPMNSTIKEGETVVTSGLGGYYPKGIRIGEV
TSVQSDDVKVMKTAILKTYVDFNNLQELFVVVPPSERDGIVKY

Sequences:

>Translated_283_residues
MKFFKNKLAVTVIVLSVAFLGIIIFTVKSDSKNPISGGVGTVLNPVQKVVYTISDKVHDVFDFFYNFSDVKNENNDLKKK
NLELENQLVEYNELKRQNDVLRGIVDFSKENNQYKYIGTNIIGKSGNSFVEGYTIDKGSSEGIKKDYIVISPEGLVGVVT
EVHSNWSKIQTLLNENVAVAATIEGDSNSGDGIVKGYRNGSEMQAEITNLPMNSTIKEGETVVTSGLGGYYPKGIRIGEV
TSVQSDDVKVMKTAILKTYVDFNNLQELFVVVPPSERDGIVKY
>Mature_283_residues
MKFFKNKLAVTVIVLSVAFLGIIIFTVKSDSKNPISGGVGTVLNPVQKVVYTISDKVHDVFDFFYNFSDVKNENNDLKKK
NLELENQLVEYNELKRQNDVLRGIVDFSKENNQYKYIGTNIIGKSGNSFVEGYTIDKGSSEGIKKDYIVISPEGLVGVVT
EVHSNWSKIQTLLNENVAVAATIEGDSNSGDGIVKGYRNGSEMQAEITNLPMNSTIKEGETVVTSGLGGYYPKGIRIGEV
TSVQSDDVKVMKTAILKTYVDFNNLQELFVVVPPSERDGIVKY

Specific function: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins [H]

COG id: COG1792

COG function: function code M; Cell shape-determining protein

Gene ontology:

Cell location: Inner Membrane-Anchored [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mreC family [H]

Homologues:

Organism=Escherichia coli, GI1789648, Length=243, Percent_Identity=27.5720164609054, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007221
- InterPro:   IPR005223 [H]

Pfam domain/function: PF04085 MreC [H]

EC number: NA

Molecular weight: Translated: 31245; Mature: 31245

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFFKNKLAVTVIVLSVAFLGIIIFTVKSDSKNPISGGVGTVLNPVQKVVYTISDKVHDV
CCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FDFFYNFSDVKNENNDLKKKNLELENQLVEYNELKRQNDVLRGIVDFSKENNQYKYIGTN
HHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECE
IIGKSGNSFVEGYTIDKGSSEGIKKDYIVISPEGLVGVVTEVHSNWSKIQTLLNENVAVA
EECCCCCCEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCEEEE
ATIEGDSNSGDGIVKGYRNGSEMQAEITNLPMNSTIKEGETVVTSGLGGYYPKGIRIGEV
EEEECCCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEECCC
TSVQSDDVKVMKTAILKTYVDFNNLQELFVVVPPSERDGIVKY
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MKFFKNKLAVTVIVLSVAFLGIIIFTVKSDSKNPISGGVGTVLNPVQKVVYTISDKVHDV
CCCHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
FDFFYNFSDVKNENNDLKKKNLELENQLVEYNELKRQNDVLRGIVDFSKENNQYKYIGTN
HHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECE
IIGKSGNSFVEGYTIDKGSSEGIKKDYIVISPEGLVGVVTEVHSNWSKIQTLLNENVAVA
EECCCCCCEEEEEEECCCCCCCCCCCEEEECCCCHHHHHHHHHCCHHHHHHHHCCCEEEE
ATIEGDSNSGDGIVKGYRNGSEMQAEITNLPMNSTIKEGETVVTSGLGGYYPKGIRIGEV
EEEECCCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCEEECCC
TSVQSDDVKVMKTAILKTYVDFNNLQELFVVVPPSERDGIVKY
CCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 1400224; 9384377 [H]